PubMed

Renal quality outcomes framework and eGFR: impact on secondary care.

Phillips LA, Donovan KL, Phillips AO.

QJM. 2009 Jun;102(6):415-23. Epub 2009 Apr 5.PMID: 19349287 [PubMed - indexed for MEDLINE]Related articles

Further evidence for the association of MMP9 with nephropathy in type 2 diabetes and application of DNA pooling technology to candidate gene screening.

Nair S, Phillips AO, Norton N, Spurlock G, Williams HJ, Craig KJ, Williams JD, Williams NM, Bowen T.

J Nephrol. 2008 May-Jun;21(3):400-5.PMID: 18587729 [PubMed - indexed for MEDLINE]Related articles

Diabetic nephropathy, inflammation, hyaluronan and interstitial fibrosis.

Lewis A, Steadman R, Manley P, Craig K, de la Motte C, Hascall V, Phillips AO.

Histol Histopathol. 2008 Jun;23(6):731-9.PMID: 18366011 [PubMed - indexed for MEDLINE]Related articles

Hyaluronan facilitates transforming growth factor-beta1-mediated fibroblast proliferation.

Meran S, Thomas DW, Stephens P, Enoch S, Martin J, Steadman R, Phillips AO.

J Biol Chem. 2008 Mar 7;283(10):6530-45. Epub 2008 Jan 2.PMID: 18174158 [PubMed - indexed for MEDLINE]Related articlesFree article

Y-box protein-1 controls transforming growth factor-beta1 translation in proximal tubular cells.

Fraser DJ, Phillips AO, Zhang X, van Roeyen CR, Muehlenberg P, En-Nia A, Mertens PR.

Kidney Int. 2008 Mar;73(6):724-32. Epub 2007 Dec 12.PMID: 18075498 [PubMed - indexed for MEDLINE]Related articles

Inhibition of integrin-linked kinase via a siRNA expression plasmid attenuates connective tissue growth factor-induced human proximal tubular epithelial cells to mesenchymal transition.

Liu BC, Li MX, Zhang JD, Liu XC, Zhang XL, Phillips AO.

Am J Nephrol. 2008;28(1):143-51. Epub 2007 Oct 19.PMID: 17951996 [PubMed - indexed for MEDLINE]Related articles

Glucose modulates handling of apoptotic cells by mesangial cells: involvement of TGF-beta1.

Khera TK, Martin J, Riley SG, Steadman R, Phillips AO.

Lab Invest. 2007 Jul;87(7):690-701. Epub 2007 May 28.PMID: 17530031 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptospiral outer membrane protein induces extracellular matrix accumulation through a TGF-beta1/Smad-dependent pathway.

Tian YC, Chen YC, Hung CC, Chang CT, Wu MS, Phillips AO, Yang CW.

J Am Soc Nephrol. 2006 Oct;17(10):2792-8. Epub 2006 Aug 23.PMID: 16928805 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of hyaluronan cable structure and function in renal proximal tubular epithelial cells.

Selbi W, de la Motte CA, Hascall VC, Day AJ, Bowen T, Phillips AO.

Kidney Int. 2006 Oct;70(7):1287-95. Epub 2006 Aug 9.PMID: 16900089 [PubMed - indexed for MEDLINE]Related articles

Overexpression of hyaluronan synthase 2 alters hyaluronan distribution and function in proximal tubular epithelial cells.

Selbi W, Day AJ, Rugg MS, Fülöp C, de la Motte CA, Bowen T, Hascall VC, Phillips AO.

J Am Soc Nephrol. 2006 Jun;17(6):1553-67. Epub 2006 May 10.PMID: 16687630 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose enhances mesangial cell apoptosis.

Khera T, Martin J, Riley S, Steadman R, Phillips AO.

Lab Invest. 2006 Jun;86(6):566-77.PMID: 16585941 [PubMed - indexed for MEDLINE]Related articlesFree article

Butyrate modulates TGF-beta1 generation and function: potential renal benefit for Acacia(sen) SUPERGUM (gum arabic)?

Matsumoto N, Riley S, Fraser D, Al-Assaf S, Ishimura E, Wolever T, Phillips GO, Phillips AO.

Kidney Int. 2006 Jan;69(2):257-65.PMID: 16408114 [PubMed - indexed for MEDLINE]Related articles

The impact of an out-reach clinic on referral of patients with renal impairment.

Craig KJ, Riley SG, Thomas B, Penney M, Donovan KL, Phillips AO.

Nephron Clin Pract. 2005;101(4):c168-73. Epub 2005 Aug 9.PMID: 16103721 [PubMed - indexed for MEDLINE]Related articles

Anemia and diabetes in the absence of nephropathy.

Craig KJ, Williams JD, Riley SG, Smith H, Owens DR, Worthing D, Cavill I, Phillips AO.

Diabetes Care. 2005 May;28(5):1118-23.PMID: 15855576 [PubMed - indexed for MEDLINE]Related articlesFree article

The quest for a model of type II diabetes with nephropathy: the Goto Kakizaki rat.

Janssen U, Vassiliadou A, Riley SG, Phillips AO, Floege J.

J Nephrol. 2004 Nov-Dec;17(6):769-73. Review.PMID: 15593049 [PubMed - indexed for MEDLINE]Related articles

Bone morphogenic protein-7 inhibits monocyte-stimulated TGF-beta1 generation in renal proximal tubular epithelial cells.

Zhang XL, Selbi W, de la Motte C, Hascall V, Phillips AO.

J Am Soc Nephrol. 2005 Jan;16(1):79-89. Epub 2004 Dec 1.PMID: 15574511 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyaluronan attenuates transforming growth factor-beta1-mediated signaling in renal proximal tubular epithelial cells.

Ito T, Williams JD, Fraser D, Phillips AO.

Am J Pathol. 2004 Jun;164(6):1979-88.PMID: 15161634 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyaluronan regulates transforming growth factor-beta1 receptor compartmentalization.

Ito T, Williams JD, Fraser DJ, Phillips AO.

J Biol Chem. 2004 Jun 11;279(24):25326-32. Epub 2004 Apr 14.PMID: 15084590 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiac dysfunction in the Goto-Kakizaki rat. A model of type II diabetes mellitus.

El-Omar MM, Yang ZK, Phillips AO, Shah AM.

Basic Res Cardiol. 2004 Mar;99(2):133-41. Epub 2003 Oct 7.PMID: 14963671 [PubMed - indexed for MEDLINE]Related articles

Hyaluronan and proximal tubular cell migration.

Ito T, Williams JD, Al-Assaf S, Phillips GO, Phillips AO.

Kidney Int. 2004 Mar;65(3):823-33.PMID: 14871402 [PubMed - indexed for MEDLINE]Related articles

The role of renal proximal tubular cells in diabetic nephropathy.

Phillips AO.

Curr Diab Rep. 2003 Dec;3(6):491-6. Review.PMID: 14611746 [PubMed - indexed for MEDLINE]Related articles

Role of connective tissue growth factor in mediating hypertrophy of human proximal tubular cells induced by angiotensin II.

Liu BC, Sun J, Chen Q, Ma KL, Ruan XZ, Phillips AO.

Am J Nephrol. 2003 Nov-Dec;23(6):429-37. Epub 2003 Oct 28.PMID: 14583661 [PubMed - indexed for MEDLINE]Related articles

Regulation of proximal tubular epithelial cell CD44-mediated binding and internalisation of hyaluronan.

Jones SG, Ito T, Phillips AO.

Int J Biochem Cell Biol. 2003 Sep;35(9):1361-77.PMID: 12798349 [PubMed - indexed for MEDLINE]Related articles

Identification and management of diabetic nephropathy in the diabetes clinic.

Craig KJ, Donovan K, Munnery M, Owens DR, Williams JD, Phillips AO.

Diabetes Care. 2003 Jun;26(6):1806-11.PMID: 12766114 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypertension superimposed on type II diabetes in Goto Kakizaki rats induces progressive nephropathy.

Janssen U, Riley SG, Vassiliadou A, Floege J, Phillips AO.

Kidney Int. 2003 Jun;63(6):2162-70.PMID: 12753303 [PubMed - indexed for MEDLINE]Related articles

TGF-beta1-mediated alterations of renal proximal tubular epithelial cell phenotype.

Tian YC, Fraser D, Attisano L, Phillips AO.

Am J Physiol Renal Physiol. 2003 Jul;285(1):F130-42. Epub 2003 Mar 18.PMID: 12644442 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-mediated induction of TGF-beta 1 and MCP-1 in mesothelial cells in vitro is osmolality and polyol pathway dependent.

Wong TY, Phillips AO, Witowski J, Topley N.

Kidney Int. 2003 Apr;63(4):1404-16.PMID: 12631356 [PubMed - indexed for MEDLINE]Related articles

TGF-beta1-mediated inhibition of HK-2 cell migration.

Tian YC, Phillips AO.

J Am Soc Nephrol. 2003 Mar;14(3):631-40.PMID: 12595498 [PubMed - indexed for MEDLINE]Related articlesFree article

TGF-beta1-mediated fibroblast-myofibroblast terminal differentiation-the role of Smad proteins.

Evans RA, Tian YC, Steadman R, Phillips AO.

Exp Cell Res. 2003 Jan 15;282(2):90-100.PMID: 12531695 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of irbesartan in prevention of renal lesion in streptozotocin-induced diabetic rats.

Liu BC, Chen Q, Luo DD, Sun J, Phillips AO, Ruan XZ, Liu NF.

Acta Pharmacol Sin. 2003 Jan;24(1):67-73.PMID: 12511232 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential expression of MCP-1 and its receptor CCR2 in glucose primed human mesangial cells.

Janssen U, Sowa E, Marchand P, Floege J, Phillips AO, Radeke HH.

Nephron. 2002 Dec;92(4):797-806.PMID: 12399623 [PubMed - indexed for MEDLINE]Related articles

Interaction between the transforming growth factor-beta type II receptor/Smad pathway and beta-catenin during transforming growth factor-beta1-mediated adherens junction disassembly.

Tian YC, Phillips AO.

Am J Pathol. 2002 May;160(5):1619-28.PMID: 12000714 [PubMed - indexed for MEDLINE]Related articlesFree article

Goto-Kakizaki rat is protected from proteinuria after induction of anti-Thy1 nephritis.

Riley SG, Evans RA, Davies M, Floege J, Phillips AO.

Am J Kidney Dis. 2002 May;39(5):985-1000.PMID: 11979342 [PubMed - indexed for MEDLINE]Related articles

Diabetic nephropathy: the central role of renal proximal tubular cells in tubulointerstitial injury.

Phillips AO, Steadman R.

Histol Histopathol. 2002 Jan;17(1):247-52. Review.PMID: 11813875 [PubMed - indexed for MEDLINE]Related articles

Translational regulation of renal proximal tubular epithelial cell transforming growth factor-beta1 generation by insulin.

Morrisey K, Evans RA, Wakefield L, Phillips AO.

Am J Pathol. 2001 Nov;159(5):1905-15.PMID: 11696451 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of renal proximal tubular epithelial cell fibroblast growth factor-2 generation by heparin.

Jones SG, Morrisey K, Phillips AO.

Am J Kidney Dis. 2001 Sep;38(3):597-609.PMID: 11532694 [PubMed - indexed for MEDLINE]Related articles

Regulation of renal proximal tubular epithelial cell hyaluronan generation: implications for diabetic nephropathy.

Jones S, Jones S, Phillips AO.

Kidney Int. 2001 May;59(5):1739-49.PMID: 11318944 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of prolonged hyperglycemia with glomerular hypertrophy and renal basement membrane thickening in the Goto Kakizaki model of non-insulin-dependent diabetes mellitus.

Phillips AO, Baboolal K, Riley S, Gröne H, Janssen U, Steadman R, Williams J, Floege J.

Am J Kidney Dis. 2001 Feb;37(2):400-10.PMID: 11157383 [PubMed - indexed for MEDLINE]Related articles

Diabetic nephropathy--where next?

Phillips AO.

QJM. 2000 Oct;93(10):643-6. No abstract available. Erratum in: QJM 2001 Jan;94(1):51. PMID: 11029473 [PubMed - indexed for MEDLINE]Related articlesFree article

Decreased degradation of collagen and fibronectin following exposure of proximal cells to glucose.

Phillips AO, Morrisey K, Steadman R, Williams JD.

Exp Nephrol. 1999 Sep-Dec;7(5-6):449-62.PMID: 10559643 [PubMed - indexed for MEDLINE]Related articles

Augmentation of kidney injury by basic fibroblast growth factor or platelet-derived growth factor does not induce progressive diabetic nephropathy in the Goto Kakizaki model of non-insulin-dependent diabetes.

Riley SG, Steadman R, Williams JD, Floege J, Phillips AO.

J Lab Clin Med. 1999 Sep;134(3):304-12.PMID: 10482316 [PubMed - indexed for MEDLINE]Related articles

Rodent models of nephropathy associated with type II diabetes.

Janssen U, Phillips AO, Floege J.

J Nephrol. 1999 May-Jun;12(3):159-72. Review.PMID: 10440513 [PubMed - indexed for MEDLINE]Related articles

TGF-beta1 stimulates the release of pre-formed bFGF from renal proximal tubular cells.

Jones SG, Morrisey K, Williams JD, Phillips AO.

Kidney Int. 1999 Jul;56(1):83-91.PMID: 10411682 [PubMed - indexed for MEDLINE]Related articlesFree article

Renal proximal tubular cell fibronectin accumulation in response to glucose is polyol pathway dependent

Morrisey K, Steadman R, Williams JD, Phillips AO.

Kidney Int. 1999 Jun;55(6):2548-72.PMID: 10354307 [PubMed - as supplied by publisher]Related articlesFree article

Renal proximal tubular cell fibronectin accumulation in response to glucose is polyol pathway dependent.

Morrisey K, Steadman R, Williams JD, Phillips AO.

Kidney Int. 1999 Jan;55(1):160-7.PMID: 9893124 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetic nephropathy: the modulating influence of glucose on transforming factor beta production.

Phillips AO.

Histol Histopathol. 1998 Apr;13(2):565-74. Review.PMID: 9589909 [PubMed - indexed for MEDLINE]Related articles

Exposure of human renal proximal tubular cells to glucose leads to accumulation of type IV collagen and fibronectin by decreased degradation.

Phillips AO, Steadman R, Morrisey K, Martin J, Eynstone L, Williams JD.

Kidney Int. 1997 Oct;52(4):973-84.PMID: 9328936 [PubMed - indexed for MEDLINE]Related articles

Basic fibroblast growth factor stimulates the release of preformed transforming growth factor beta 1 from human proximal tubular cells in the absence of de novo gene transcription or mRNA translation.

Phillips AO, Topley N, Morrisey K, Williams JD, Steadman R.

Lab Invest. 1997 Apr;76(4):591-600.PMID: 9111519 [PubMed - indexed for MEDLINE]Related articles

Polarity of stimulation and secretion of transforming growth factor-beta 1 by cultured proximal tubular cells.

Phillips AO, Steadman R, Morrisey K, Williams JD.

Am J Pathol. 1997 Mar;150(3):1101-11.PMID: 9060845 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of TGF-beta 1 synthesis in D-glucose primed human proximal tubular cells by IL-1 beta and TNF alpha.

Phillips AO, Topley N, Steadman R, Morrisey K, Williams JD.

Kidney Int. 1996 Nov;50(5):1546-54.PMID: 8914021 [PubMed - indexed for MEDLINE]Related articles