PubMed

Toll-like Receptor 9 Activation is a Key Mechanism for the Maintenance of Chronic Lung Inflammation.

Ito T, Schaller M, Raymond T, Joshi AD, Coelho AL, Frantz FG, Carson Iv WF, Hogaboam CM, Lukacs NW, Standiford TJ, Phan SH, Chensue SW, Kunkel SL.

Am J Respir Crit Care Med. 2009 Sep 24. [Epub ahead of print]PMID: 19797157 [PubMed - as supplied by publisher]Related articles

Endothelial-mesenchymal transition in bleomycin-induced pulmonary fibrosis.

Hashimoto N, Phan SH, Imaizumi K, Matsuo M, Nakashima H, Kawabe T, Shimokata K, Hasegawa Y.

Am J Respir Cell Mol Biol. 2009 Sep 18. [Epub ahead of print]PMID: 19767450 [PubMed - as supplied by publisher]Related articles

Erythromycin-induced CXCR4 expression on microvascular endothelial cells.

Takagi Y, Hashimoto N, Phan SH, Imaizumi K, Matsuo M, Nakashima H, Hashimoto I, Hayashi Y, Kawabe T, Shimokata K, Hasegawa Y.

Am J Physiol Lung Cell Mol Physiol. 2009 Sep;297(3):L420-31. Epub 2009 Jun 5.PMID: 19502290 [PubMed - indexed for MEDLINE]Related articles

Nkx2.5/Csx Represses Myofibroblast Differentiation.

Hu B, Wu YM, Wu Z, Phan SH.

Am J Respir Cell Mol Biol. 2009 Apr 24. [Epub ahead of print]PMID: 19395679 [PubMed - as supplied by publisher]Related articles

Recent advances in molecular targets and treatment of idiopathic pulmonary fibrosis: focus on TGFbeta signaling and the myofibroblast.

Gharaee-Kermani M, Hu B, Phan SH, Gyetko MR.

Curr Med Chem. 2009;16(11):1400-17. Review.PMID: 19355895 [PubMed - indexed for MEDLINE]Related articles

Notch1 signaling in FIZZ1 induction of myofibroblast differentiation.

Liu T, Hu B, Choi YY, Chung M, Ullenbruch M, Yu H, Lowe JB, Phan SH.

Am J Pathol. 2009 May;174(5):1745-55. Epub 2009 Apr 6.PMID: 19349363 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of stem cell factor and bone marrow-derived fibroblasts in airway remodeling.

Dolgachev VA, Ullenbruch MR, Lukacs NW, Phan SH.

Am J Pathol. 2009 Feb;174(2):390-400. Epub 2009 Jan 15.PMID: 19147822 [PubMed - indexed for MEDLINE]Related articlesFree article

Resident cellular components of the human lung: current knowledge and goals for research on cell phenotyping and function.

Franks TJ, Colby TV, Travis WD, Tuder RM, Reynolds HY, Brody AR, Cardoso WV, Crystal RG, Drake CJ, Engelhardt J, Frid M, Herzog E, Mason R, Phan SH, Randell SH, Rose MC, Stevens T, Serge J, Sunday ME, Voynow JA, Weinstein BM, Whitsett J, Williams MC.

Proc Am Thorac Soc. 2008 Sep 15;5(7):763-6.PMID: 18757314 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of urokinase in idiopathic pulmonary fibrosis and implication for therapy.

Gharaee-Kermani M, Hu B, Phan SH, Gyetko MR.

Expert Opin Investig Drugs. 2008 Jun;17(6):905-16. Review.PMID: 18491991 [PubMed - indexed for MEDLINE]Related articles

Biology of fibroblasts and myofibroblasts.

Phan SH.

Proc Am Thorac Soc. 2008 Apr 15;5(3):334-7.PMID: 18403329 [PubMed - indexed for MEDLINE]Related articlesFree article

PPAR-gamma agonists inhibit profibrotic phenotypes in human lung fibroblasts and bleomycin-induced pulmonary fibrosis.

Milam JE, Keshamouni VG, Phan SH, Hu B, Gangireddy SR, Hogaboam CM, Standiford TJ, Thannickal VJ, Reddy RC.

Am J Physiol Lung Cell Mol Physiol. 2008 May;294(5):L891-901. Epub 2007 Dec 27.PMID: 18162602 [PubMed - indexed for MEDLINE]Related articlesFree article

Telomerase activity is required for bleomycin-induced pulmonary fibrosis in mice.

Liu T, Chung MJ, Ullenbruch M, Yu H, Jin H, Hu B, Choi YY, Ishikawa F, Phan SH.

J Clin Invest. 2007 Dec;117(12):3800-9.PMID: 18008008 [PubMed - indexed for MEDLINE]Related articlesFree article

Current and emerging drugs for idiopathic pulmonary fibrosis.

Gharaee-Kermani M, Hu B, Thannickal VJ, Phan SH, Gyetko MR.

Expert Opin Emerg Drugs. 2007 Nov;12(4):627-46. Review.PMID: 17979604 [PubMed - indexed for MEDLINE]Related articles

The myofibroblast: one function, multiple origins.

Hinz B, Phan SH, Thannickal VJ, Galli A, Bochaton-Piallat ML, Gabbiani G.

Am J Pathol. 2007 Jun;170(6):1807-16. Review.PMID: 17525249 [PubMed - indexed for MEDLINE]Related articlesFree article

Antiapoptotic effect of found in inflammatory zone (FIZZ)1 on mouse lung fibroblasts.

Chung MJ, Liu T, Ullenbruch M, Phan SH.

J Pathol. 2007 Jun;212(2):180-7.PMID: 17492827 [PubMed - indexed for MEDLINE]Related articles

Therapies for bleomycin induced lung fibrosis through regulation of TGF-beta1 induced collagen gene expression.

Cutroneo KR, White SL, Phan SH, Ehrlich HP.

J Cell Physiol. 2007 Jun;211(3):585-9. Review.PMID: 17387717 [PubMed - indexed for MEDLINE]Related articles

New insights into the pathogenesis and treatment of idiopathic pulmonary fibrosis: a potential role for stem cells in the lung parenchyma and implications for therapy.

Gharaee-Kermani M, Gyetko MR, Hu B, Phan SH.

Pharm Res. 2007 May;24(5):819-41. Epub 2007 Mar 1. Review.PMID: 17333393 [PubMed - indexed for MEDLINE]Related articles

An essential role for CCAAT/enhancer binding protein beta in bleomycin-induced pulmonary fibrosis.

Hu B, Ullenbruch MR, Jin H, Gharaee-Kermani M, Phan SH.

J Pathol. 2007 Mar;211(4):455-62.PMID: 17177178 [PubMed - indexed for MEDLINE]Related articles

Gut-enriched Krüppel-like factor interaction with Smad3 inhibits myofibroblast differentiation.

Hu B, Wu Z, Liu T, Ullenbruch MR, Jin H, Phan SH.

Am J Respir Cell Mol Biol. 2007 Jan;36(1):78-84. Epub 2006 Jul 20.PMID: 16858008 [PubMed - indexed for MEDLINE]Related articlesFree article

The extrapulmonary origin of fibroblasts: stem/progenitor cells and beyond.

Lama VN, Phan SH.

Proc Am Thorac Soc. 2006 Jun;3(4):373-6. Review.PMID: 16738203 [PubMed - indexed for MEDLINE]Related articlesFree article

Telomerase regulation of myofibroblast differentiation.

Liu T, Hu B, Chung MJ, Ullenbruch M, Jin H, Phan SH.

Am J Respir Cell Mol Biol. 2006 May;34(5):625-33. Epub 2006 Jan 19.PMID: 16424384 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of Eotaxin-1 (CCL11) and CC chemokine receptor 3 (CCR3) in bleomycin-induced lung injury and fibrosis.

Huaux F, Gharaee-Kermani M, Liu T, Morel V, McGarry B, Ullenbruch M, Kunkel SL, Wang J, Xing Z, Phan SH.

Am J Pathol. 2005 Dec;167(6):1485-96.PMID: 16314464 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular mechanisms of and possible treatment strategies for idiopathic pulmonary fibrosis.

Gharaee-Kermani M, Phan SH.

Curr Pharm Des. 2005;11(30):3943-71. Review.PMID: 16305523 [PubMed - indexed for MEDLINE]Related articles

Role of Smad3 in the regulation of rat telomerase reverse transcriptase by TGFbeta.

Hu B, Tack DC, Liu T, Wu Z, Ullenbruch MR, Phan SH.

Oncogene. 2006 Feb 16;25(7):1030-41.PMID: 16205635 [PubMed - indexed for MEDLINE]Related articles

Negative regulation of myofibroblast differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on chromosome 10).

White ES, Atrasz RG, Hu B, Phan SH, Stambolic V, Mak TW, Hogaboam CM, Flaherty KR, Martinez FJ, Kontos CD, Toews GB.

Am J Respir Crit Care Med. 2006 Jan 1;173(1):112-21. Epub 2005 Sep 22.PMID: 16179636 [PubMed - indexed for MEDLINE]Related articlesFree article

Animal models of pulmonary fibrosis.

Gharaee-Kermani M, Ullenbruch M, Phan SH.

Methods Mol Med. 2005;117:251-9.PMID: 16118457 [PubMed - indexed for MEDLINE]Related articles

Gender-based differences in bleomycin-induced pulmonary fibrosis.

Gharaee-Kermani M, Hatano K, Nozaki Y, Phan SH.

Am J Pathol. 2005 Jun;166(6):1593-606.PMID: 15920145 [PubMed - indexed for MEDLINE]Related articlesFree article

Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease.

Lin J, Patel SR, Cheng X, Cho EA, Levitan I, Ullenbruch M, Phan SH, Park JM, Dressler GR.

Nat Med. 2005 Apr;11(4):387-93. Epub 2005 Mar 27.PMID: 15793581 [PubMed - indexed for MEDLINE]Related articles

Inhibition of key cytokines by tetrathiomolybdate in the bleomycin model of pulmonary fibrosis.

Brewer GJ, Dick R, Ullenbruch MR, Jin H, Phan SH.

J Inorg Biochem. 2004 Dec;98(12):2160-7.PMID: 15541506 [PubMed - indexed for MEDLINE]Related articles

CCAAT/enhancer-binding protein beta isoforms and the regulation of alpha-smooth muscle actin gene expression by IL-1 beta.

Hu B, Wu Z, Jin H, Hashimoto N, Liu T, Phan SH.

J Immunol. 2004 Oct 1;173(7):4661-8.PMID: 15383601 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of found in inflammatory zone 1 expression in bleomycin-induced lung fibrosis: role of IL-4/IL-13 and mediation via STAT-6.

Liu T, Jin H, Ullenbruch M, Hu B, Hashimoto N, Moore B, McKenzie A, Lukacs NW, Phan SH.

J Immunol. 2004 Sep 1;173(5):3425-31.PMID: 15322207 [PubMed - indexed for MEDLINE]Related articlesFree article

FIZZ1 stimulation of myofibroblast differentiation.

Liu T, Dhanasekaran SM, Jin H, Hu B, Tomlins SA, Chinnaiyan AM, Phan SH.

Am J Pathol. 2004 Apr;164(4):1315-26.PMID: 15039219 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of the effect of interleukin-10 on silica-induced lung fibrosis in mice.

Barbarin V, Arras M, Misson P, Delos M, McGarry B, Phan SH, Lison D, Huaux F.

Am J Respir Cell Mol Biol. 2004 Jul;31(1):78-85. Epub 2004 Feb 19.PMID: 14975940 [PubMed - indexed for MEDLINE]Related articlesFree article

Bone marrow-derived progenitor cells in pulmonary fibrosis.

Hashimoto N, Jin H, Liu T, Chensue SW, Phan SH.

J Clin Invest. 2004 Jan;113(2):243-52.PMID: 14722616 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic inhaled ovalbumin exposure induces antigen-dependent but not antigen-specific inhalational tolerance in a murine model of allergic airway disease.

Schramm CM, Puddington L, Wu C, Guernsey L, Gharaee-Kermani M, Phan SH, Thrall RS.

Am J Pathol. 2004 Jan;164(1):295-304.PMID: 14695342 [PubMed - indexed for MEDLINE]Related articlesFree article

CC-chemokine receptor 2 required for bleomycin-induced pulmonary fibrosis.

Gharaee-Kermani M, McCullumsmith RE, Charo IF, Kunkel SL, Phan SH.

Cytokine. 2003 Dec 21;24(6):266-76.PMID: 14609568 [PubMed - indexed for MEDLINE]Related articles

Eosinophils and T lymphocytes possess distinct roles in bleomycin-induced lung injury and fibrosis.

Huaux F, Liu T, McGarry B, Ullenbruch M, Xing Z, Phan SH.

J Immunol. 2003 Nov 15;171(10):5470-81.PMID: 14607953 [PubMed - indexed for MEDLINE]Related articlesFree article

Fibroblast phenotypes in pulmonary fibrosis.

Phan SH.

Am J Respir Cell Mol Biol. 2003 Sep;29(3 Suppl):S87-92. Review. No abstract available. PMID: 14503563 [PubMed - indexed for MEDLINE]Related articles

Involvement of serum response factor isoforms in myofibroblast differentiation during bleomycin-induced lung injury.

Yang Y, Zhe X, Phan SH, Ullenbruch M, Schuger L.

Am J Respir Cell Mol Biol. 2003 Nov;29(5):583-90. Epub 2003 May 30.PMID: 12777247 [PubMed - indexed for MEDLINE]Related articlesFree article

TGF-beta1-induced Smad 3 binding to the Smad 7 gene: knockout of Smad 7 gene transcription by sense phosphorothioate oligos, autoregulation, and effect on TGF-beta1 secretion: bleomycin acts through TGF-beta1.

Cutroneo KR, Phan SH.

J Cell Biochem. 2003 Jun 1;89(3):474-83.PMID: 12761881 [PubMed - indexed for MEDLINE]Related articles

Nephrogenic fibrosing dermopathy: a novel cutaneous fibrosing disorder in patients with renal failure.

Swartz RD, Crofford LJ, Phan SH, Ike RW, Su LD.

Am J Med. 2003 May;114(7):563-72.PMID: 12753880 [PubMed - indexed for MEDLINE]Related articles

Smad3 mediates transforming growth factor-beta-induced alpha-smooth muscle actin expression.

Hu B, Wu Z, Phan SH.

Am J Respir Cell Mol Biol. 2003 Sep;29(3 Pt 1):397-404. Epub 2003 Apr 17.PMID: 12702545 [PubMed - indexed for MEDLINE]Related articlesFree article

Tetrathiomolybdate therapy protects against bleomycin-induced pulmonary fibrosis in mice.

Brewer GJ, Ullenbruch MR, Dick R, Olivarez L, Phan SH.

J Lab Clin Med. 2003 Mar;141(3):210-6.PMID: 12624602 [PubMed - indexed for MEDLINE]Related articles

Dual roles of IL-4 in lung injury and fibrosis.

Huaux F, Liu T, McGarry B, Ullenbruch M, Phan SH.

J Immunol. 2003 Feb 15;170(4):2083-92.PMID: 12574379 [PubMed - indexed for MEDLINE]Related articlesFree article

The myofibroblast in pulmonary fibrosis.

Phan SH.

Chest. 2002 Dec;122(6 Suppl):286S-289S. Review.PMID: 12475801 [PubMed - indexed for MEDLINE]Related articlesFree article

A profibrotic function of IL-12p40 in experimental pulmonary fibrosis.

Huaux F, Arras M, Tomasi D, Barbarin V, Delos M, Coutelier JP, Vink A, Phan SH, Renauld JC, Lison D.

J Immunol. 2002 Sep 1;169(5):2653-61.PMID: 12193738 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of telomerase activity in rat lung fibroblasts.

Liu T, Nozaki Y, Phan SH.

Am J Respir Cell Mol Biol. 2002 May;26(5):534-40.PMID: 11970904 [PubMed - indexed for MEDLINE]Related articlesFree article

Protection from pulmonary fibrosis in leukotriene-deficient mice.

Peters-Golden M, Bailie M, Marshall T, Wilke C, Phan SH, Toews GB, Moore BB.

Am J Respir Crit Care Med. 2002 Jan 15;165(2):229-35.PMID: 11790660 [PubMed - indexed for MEDLINE]Related articlesFree article

Lung interleukin-4 gene expression in a murine model of bleomycin-induced pulmonary fibrosis.

Gharaee-Kermani M, Nozaki Y, Hatano K, Phan SH.

Cytokine. 2001 Aug 7;15(3):138-47.PMID: 11554783 [PubMed - indexed for MEDLINE]Related articles

Role of cytokines and cytokine therapy in wound healing and fibrotic diseases.

Gharaee-Kermani M, Phan SH.

Curr Pharm Des. 2001 Jul;7(11):1083-103. Review.PMID: 11472255 [PubMed - indexed for MEDLINE]Related articles