PubMed

Cleavage of functional IL-2 receptor alpha chain (CD25) from murine corneal and conjunctival epithelia by MMP-9.

De Paiva CS, Yoon KC, Pangelinan SB, Pham S, Puthenparambil LM, Chuang EY, Farley WJ, Stern ME, Li DQ, Pflugfelder SC.

J Inflamm (Lond). 2009 Oct 31;6:31.PMID: 19878594 [PubMed - in process]Related articlesFree article

Expression of CXCL9, CXCL10, and CXCL11, and CXCR3 in the Tear Film and Ocular Surface of Patients with Dry Eye Syndrome.

Yoon KC, Park CS, You IC, Choi HJ, Lee KH, Im SK, Park HY, Pflugfelder SC.

Invest Ophthalmol Vis Sci. 2009 Oct 22. [Epub ahead of print]PMID: 19850844 [PubMed - as supplied by publisher]Related articles

Corneal subepithelial fibrosis is associated with high tear epidermal growth factor levels in dry eye conditions.

Rao K, Farley WJ, Pflugfelder SC.

Invest Ophthalmol Vis Sci. 2009 Oct 8. [Epub ahead of print]PMID: 19815739 [PubMed - as supplied by publisher]Related articles

Toll-like receptors mediate induction of peptidoglycan recognition proteins in human corneal epithelial cells.

Ma P, Wang Z, Pflugfelder SC, Li DQ.

Exp Eye Res. 2009 Sep 30. [Epub ahead of print]PMID: 19799901 [PubMed - as supplied by publisher]Related articles

Induction of Th17 differentiation by corneal epithelial-derived cytokines.

Zheng X, Bian F, Ma P, De Paiva CS, Stern M, Pflugfelder SC, Li DQ.

J Cell Physiol. 2010 Jan;222(1):95-102.PMID: 19746420 [PubMed - in process]Related articles

Corneal epithelial opacity in dysfunctional tear syndrome.

Chen JJ, Rao K, Pflugfelder SC.

Am J Ophthalmol. 2009 Sep;148(3):376-82. Epub 2009 Jul 9.PMID: 19541283 [PubMed - indexed for MEDLINE]Related articles

Spontaneous T cell mediated keratoconjunctivitis in Aire-deficient mice.

Yeh S, de Paiva CS, Hwang CS, Trinca K, Lingappan A, Rafati JK, Farley WJ, Li DQ, Pflugfelder SC.

Br J Ophthalmol. 2009 Sep;93(9):1260-4. Epub 2009 May 7.PMID: 19429577 [PubMed - indexed for MEDLINE]Related articles

Topical ophthalmic cyclosporine: pharmacology and clinical uses.

Donnenfeld E, Pflugfelder SC.

Surv Ophthalmol. 2009 May-Jun;54(3):321-38. Review.PMID: 19422961 [PubMed - indexed for MEDLINE]Related articles

Immunoregulation on the ocular surface: 2nd Cullen Symposium.

Pflugfelder SC, Stern ME; Symposium Participants.

Ocul Surf. 2009 Apr;7(2):67-77. Review.PMID: 19383275 [PubMed - indexed for MEDLINE]Related articles

Rationale for anti-inflammatory therapy in dry eye syndrome.

Paiva CS, Pflugfelder SC.

Arq Bras Oftalmol. 2008 Nov-Dec;71(6 Suppl):89-95. Review.PMID: 19274418 [PubMed - indexed for MEDLINE]Related articlesFree article

Production and activity of matrix metalloproteinase-9 on the ocular surface increase in dysfunctional tear syndrome.

Chotikavanich S, de Paiva CS, Li de Q, Chen JJ, Bian F, Farley WJ, Pflugfelder SC.

Invest Ophthalmol Vis Sci. 2009 Jul;50(7):3203-9. Epub 2009 Feb 28.PMID: 19255163 [PubMed - indexed for MEDLINE]Related articles

IL-17 disrupts corneal barrier following desiccating stress.

De Paiva CS, Chotikavanich S, Pangelinan SB, Pitcher JD 3rd, Fang B, Zheng X, Ma P, Farley WJ, Siemasko KF, Niederkorn JY, Stern ME, Li DQ, Pflugfelder SC.

Mucosal Immunol. 2009 May;2(3):243-53. Epub 2009 Feb 25.PMID: 19242409 [PubMed - indexed for MEDLINE]Related articles

Human corneal epithelium-derived thymic stromal lymphopoietin links the innate and adaptive immune responses via TLRs and Th2 cytokines.

Ma P, Bian F, Wang Z, Zheng X, Chotikavanich S, Pflugfelder SC, Li DQ.

Invest Ophthalmol Vis Sci. 2009 Jun;50(6):2702-9. Epub 2009 Jan 17.PMID: 19151401 [PubMed - indexed for MEDLINE]Related articles

Tear cytokine profiles in dysfunctional tear syndrome.

Lam H, Bleiden L, de Paiva CS, Farley W, Stern ME, Pflugfelder SC.

Am J Ophthalmol. 2009 Feb;147(2):198-205. e1. Epub 2008 Nov 7.PMID: 18992869 [PubMed - indexed for MEDLINE]Related articles

Glial cell-derived neurotrophic factor gene delivery enhances survival of human corneal epithelium in culture and the overexpression of GDNF in bioengineered constructs.

Qi H, Shine HD, Li DQ, de Paiva CS, Farley WJ, Jones DB, Pflugfelder SC.

Exp Eye Res. 2008 Dec;87(6):580-6. Epub 2008 Oct 7.PMID: 18938159 [PubMed - indexed for MEDLINE]Related articles

Epithelial-immune cell interaction in dry eye.

Pflugfelder SC, de Paiva CS, Li DQ, Stern ME.

Cornea. 2008 Sep;27 Suppl 1:S9-11. Review.PMID: 18813079 [PubMed - indexed for MEDLINE]Related articles

Effects of contact lens multipurpose solutions on human corneal epithelial survival and barrier function.

Chuang EY, Li DQ, Bian F, Zheng X, Pflugfelder SC.

Eye Contact Lens. 2008 Sep;34(5):281-6.PMID: 18779668 [PubMed - indexed for MEDLINE]Related articles

Desiccating stress decreases apical corneal epithelial cell size--modulation by the metalloproteinase inhibitor doxycycline.

Beardsley RM, De Paiva CS, Power DF, Pflugfelder SC.

Cornea. 2008 Sep;27(8):935-40.PMID: 18724157 [PubMed - indexed for MEDLINE]Related articles

Expression of glial cell-derived neurotrophic factor and its receptor in the stem-cell-containing human limbal epithelium.

Qi H, Li DQ, Bian F, Chuang EY, Jones DB, Pflugfelder SC.

Br J Ophthalmol. 2008 Sep;92(9):1269-74.PMID: 18723744 [PubMed - indexed for MEDLINE]Related articles

In vitro expanded CD4+CD25+Foxp3+ regulatory T cells maintain a normal phenotype and suppress immune-mediated ocular surface inflammation.

Siemasko KF, Gao J, Calder VL, Hanna R, Calonge M, Pflugfelder SC, Niederkorn JY, Stern ME.

Invest Ophthalmol Vis Sci. 2008 Dec;49(12):5434-40. Epub 2008 Jul 24.PMID: 18658093 [PubMed - indexed for MEDLINE]Related articles

Interleukin-1 receptor-1-deficient mice show attenuated production of ocular surface inflammatory cytokines in experimental dry eye.

Narayanan S, Corrales RM, Farley W, McDermott AM, Pflugfelder SC.

Cornea. 2008 Aug;27(7):811-7.PMID: 18650668 [PubMed - indexed for MEDLINE]Related articles

Effects of osmoprotectants on hyperosmolar stress in cultured human corneal epithelial cells.

Corrales RM, Luo L, Chang EY, Pflugfelder SC.

Cornea. 2008 Jun;27(5):574-9.PMID: 18520508 [PubMed - indexed for MEDLINE]Related articles

Prevalence, burden, and pharmacoeconomics of dry eye disease.

Pflugfelder SC.

Am J Manag Care. 2008 Apr;14(3 Suppl):S102-6. Review.PMID: 18452369 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of sequential artificial tear and cyclosporine emulsion therapy on conjunctival goblet cell density and transforming growth factor-beta2 production.

Pflugfelder SC, De Paiva CS, Villarreal AL, Stern ME.

Cornea. 2008 Jan;27(1):64-9.PMID: 18245969 [PubMed - indexed for MEDLINE]Related articles

Hyperosmolarity-induced cornification of human corneal epithelial cells is regulated by JNK MAPK.

Chen Z, Tong L, Li Z, Yoon KC, Qi H, Farley W, Li DQ, Pflugfelder SC.

Invest Ophthalmol Vis Sci. 2008 Feb;49(2):539-49.PMID: 18234997 [PubMed - indexed for MEDLINE]Related articlesFree article

Bilateral acanthamoeba keratitis.

Wilhelmus KR, Jones DB, Matoba AY, Hamill MB, Pflugfelder SC, Weikert MP.

Am J Ophthalmol. 2008 Feb;145(2):193-197.PMID: 18222188 [PubMed - indexed for MEDLINE]Related articles

Desiccating environmental stress exacerbates autoimmune lacrimal keratoconjunctivitis in non-obese diabetic mice.

Yoon KC, De Paiva CS, Qi H, Chen Z, Farley WJ, Li DQ, Stern ME, Pflugfelder SC.

J Autoimmun. 2008 Jun;30(4):212-21. Epub 2007 Nov 7.PMID: 17988834 [PubMed - indexed for MEDLINE]Related articlesFree article

Patterned expression of neurotrophic factors and receptors in human limbal and corneal regions.

Qi H, Chuang EY, Yoon KC, de Paiva CS, Shine HD, Jones DB, Pflugfelder SC, Li DQ.

Mol Vis. 2007 Oct 16;13:1934-41.PMID: 17982417 [PubMed - indexed for MEDLINE]Related articlesFree article

Nerve growth factor and its receptor TrkA serve as potential markers for human corneal epithelial progenitor cells.

Qi H, Li DQ, Shine HD, Chen Z, Yoon KC, Jones DB, Pflugfelder SC.

Exp Eye Res. 2008 Jan;86(1):34-40. Epub 2007 Sep 15.PMID: 17980361 [PubMed - indexed for MEDLINE]Related articlesFree article

Future directions in therapeutic interventions for conjunctival inflammatory disorders.

Pflugfelder SC, Stern ME.

Curr Opin Allergy Clin Immunol. 2007 Oct;7(5):450-3. Review.PMID: 17873588 [PubMed - indexed for MEDLINE]Related articles

Strain-related cytokine profiles on the murine ocular surface in response to desiccating stress.

Corrales RM, Villarreal A, Farley W, Stern ME, Li DQ, Pflugfelder SC.

Cornea. 2007 Jun;26(5):579-84.PMID: 17525655 [PubMed - indexed for MEDLINE]Related articles

Expression of Th-1 chemokines and chemokine receptors on the ocular surface of C57BL/6 mice: effects of desiccating stress.

Yoon KC, De Paiva CS, Qi H, Chen Z, Farley WJ, Li DQ, Pflugfelder SC.

Invest Ophthalmol Vis Sci. 2007 Jun;48(6):2561-9.PMID: 17525185 [PubMed - indexed for MEDLINE]Related articlesFree article

Dry eye-induced conjunctival epithelial squamous metaplasia is modulated by interferon-gamma.

De Paiva CS, Villarreal AL, Corrales RM, Rahman HT, Chang VY, Farley WJ, Stern ME, Niederkorn JY, Li DQ, Pflugfelder SC.

Invest Ophthalmol Vis Sci. 2007 Jun;48(6):2553-60.PMID: 17525184 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperosmolarity-induced apoptosis in human corneal epithelial cells is mediated by cytochrome c and MAPK pathways.

Luo L, Li DQ, Pflugfelder SC.

Cornea. 2007 May;26(4):452-60.PMID: 17457195 [PubMed - indexed for MEDLINE]Related articles

Prominent corneal nerves in a patient with multiple myeloma.

Parghi C, McKnight GT, Pflugfelder SC.

Cornea. 2007 Feb;26(2):220-2.PMID: 17251817 [PubMed - indexed for MEDLINE]Related articles

Matrix metalloproteinases in corneal inflammation.

Li DQ, Pflugfelder SC.

Ocul Surf. 2005 Oct;3(4 Suppl):S198-202.PMID: 17216119 [PubMed]Related articles

Evaluation of ocular surface inflammation in the presence of dry eye and allergic conjunctival disease.

Stern ME, Siemasko KF, Gao J, Calonge M, Niederkorn JY, Pflugfelder SC.

Ocul Surf. 2005 Oct;3(4 Suppl):S161-4.PMID: 17216110 [PubMed]Related articles

Stress-activated protein kinase signaling pathways in dry eye and ocular surface disease.

Pflugfelder SC, de Paiva CS, Tong L, Luo L, Stern ME, Li DQ.

Ocul Surf. 2005 Oct;3(4 Suppl):S154-7.PMID: 17216108 [PubMed]Related articles

Pathways of corneal and ocular surface inflammation: a perspective from the cullen symposium.

McDermott AM, Perez V, Huang AJ, Pflugfelder SC, Stern ME, Baudouin C, Beuerman RW, Burns AR, Calder VL, Calonge M, Chodosh J, Coster DJ, Dana R, Hazlett LD, Jones DB, Kim SK, Knop E, Li DQ, Mitchell BM, Niederkorn JY, Pearlman E, Wilhelmus KR, Kurie E.

Ocul Surf. 2005 Oct;3(4 Suppl):S131-8.PMID: 17216102 [PubMed]Related articles

Inflammation in dry eye.

Stern ME, Pflugfelder SC.

Ocul Surf. 2004 Apr;2(2):124-30.PMID: 17216083 [PubMed]Related articles

Dysfunctional tear syndrome: a Delphi approach to treatment recommendations.

Behrens A, Doyle JJ, Stern L, Chuck RS, McDonnell PJ, Azar DT, Dua HS, Hom M, Karpecki PM, Laibson PR, Lemp MA, Meisler DM, Del Castillo JM, O'Brien TP, Pflugfelder SC, Rolando M, Schein OD, Seitz B, Tseng SC, van Setten G, Wilson SE, Yiu SC; Dysfunctional tear syndrome study group.

Cornea. 2006 Sep;25(8):900-7.PMID: 17102664 [PubMed - indexed for MEDLINE]Related articles

Effect of topical ophthalmic epinastine and olopatadine on tear volume in mice.

Villareal AL, Farley W, Pflugfelder SC.

Eye Contact Lens. 2006 Dec;32(6):272-6.PMID: 17099387 [PubMed - indexed for MEDLINE]Related articles

Management of the late ocular sequelae of Stevens-Johnson syndrome.

Wall V, Yen MT, Yang MC, Huang AJ, Pflugfelder SC.

Ocul Surf. 2003 Oct;1(4):192-201.PMID: 17075650 [PubMed]Related articles

The Ocular Surface Center at the Baylor College of Medicine, Houston.

Pflugfelder SC.

Ocul Surf. 2003 Apr;1(2):89-90. No abstract available. PMID: 17075639 [PubMed]Related articles

Anti-inflammatory therapy of dry eye.

Pflugfelder SC.

Ocul Surf. 2003 Jan;1(1):31-6.PMID: 17075627 [PubMed]Related articles

Integrating restasis into the management of dry eye.

Pflugfelder SC.

Int Ophthalmol Clin. 2006 Fall;46(4):101-3. Review. No abstract available. PMID: 17060796 [PubMed - indexed for MEDLINE]Related articles

Transglutaminase participates in UVB-induced cell death pathways in human corneal epithelial cells.

Tong L, Chen Z, De Paiva CS, Beuerman R, Li DQ, Pflugfelder SC.

Invest Ophthalmol Vis Sci. 2006 Oct;47(10):4295-301.PMID: 17003418 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeted inhibition of p57 and p15 blocks transforming growth factor beta-inhibited proliferation of primary cultured human limbal epithelial cells.

Chen Z, Li DQ, Tong L, Stewart P, Chu C, Pflugfelder SC.

Mol Vis. 2006 Aug 23;12:983-94.PMID: 16943770 [PubMed - indexed for MEDLINE]Related articlesFree article

Desiccating stress stimulates expression of matrix metalloproteinases by the corneal epithelium.

Corrales RM, Stern ME, De Paiva CS, Welch J, Li DQ, Pflugfelder SC.

Invest Ophthalmol Vis Sci. 2006 Aug;47(8):3293-302.PMID: 16877394 [PubMed - indexed for MEDLINE]Related articlesFree article

Is autologous serum a tonic for the ailing corneal epithelium?

Pflugfelder SC.

Am J Ophthalmol. 2006 Aug;142(2):316-7. No abstract available. PMID: 16876515 [PubMed - indexed for MEDLINE]Related articles