PubMed

Safety and efficacy of alpha-1-antitrypsin augmentation therapy in the treatment of patients with alpha-1-antitrypsin deficiency.

Petrache I, Hajjar J, Campos M.

Biologics. 2009;3:193-204. Epub 2009 Jul 13.PMID: 19707408 [PubMed - in process]Related articlesFree article

A monoclonal rat anti-mouse EMAP II antibody that functionally neutralizes pro- and mature-EMAP II in vitro.

Rajashekhar G, Mitnacht-Kraus R, Ispe U, Garrison J, Hou Y, Taylor B, Petrache I, Vestweber D, Clauss M.

J Immunol Methods. 2009 Oct 31;350(1-2):22-8. Epub 2009 Aug 14.PMID: 19683532 [PubMed - indexed for MEDLINE]Related articles

Spinal ceramide and neuronal apoptosis in morphine antinociceptive tolerance.

Bryant L, Doyle T, Chen Z, Cuzzocrea S, Masini E, Vinci MC, Esposito E, Mazzon E, Petrusca DN, Petrache I, Salvemini D.

Neurosci Lett. 2009 Sep 29;463(1):49-53. Epub 2009 Jul 23.PMID: 19631718 [PubMed - indexed for MEDLINE]Related articles

Type V collagen-induced oral tolerance plus low-dose cyclosporine prevents rejection of MHC class I and II incompatible lung allografts.

Yamada Y, Sekine Y, Yoshida S, Yasufuku K, Petrache I, Benson HL, Brand DD, Yoshino I, Wilkes DS.

J Immunol. 2009 Jul 1;183(1):237-45.PMID: 19542435 [PubMed - indexed for MEDLINE]Related articles

Mechanism of alpha-1 antitrypsin endocytosis by lung endothelium.

Sohrab S, Petrusca DN, Lockett AD, Schweitzer KS, Rush NI, Gu Y, Kamocki K, Garrison J, Petrache I.

FASEB J. 2009 Sep;23(9):3149-58. Epub 2009 May 7.PMID: 19423638 [PubMed - indexed for MEDLINE]Related articles

CFTR regulation of intracellular pH and ceramides is required for lung endothelial cell apoptosis.

Noe J, Petrusca D, Rush N, Deng P, VanDemark M, Berdyshev E, Gu Y, Smith P, Schweitzer K, Pilewsky J, Natarajan V, Xu Z, Obukhov AG, Petrache I.

Am J Respir Cell Mol Biol. 2009 Sep;41(3):314-23. Epub 2009 Jan 23.PMID: 19168702 [PubMed - indexed for MEDLINE]Related articles

Spinal ceramide modulates the development of morphine antinociceptive tolerance via peroxynitrite-mediated nitroxidative stress and neuroimmune activation.

Ndengele MM, Cuzzocrea S, Masini E, Vinci MC, Esposito E, Muscoli C, Petrusca DN, Mollace V, Mazzon E, Li D, Petrache I, Matuschak GM, Salvemini D.

J Pharmacol Exp Ther. 2009 Apr;329(1):64-75. Epub 2008 Nov 25.PMID: 19033555 [PubMed - indexed for MEDLINE]Related articles

Anti-type V collagen humoral immunity in lung transplant primary graft dysfunction.

Iwata T, Philipovskiy A, Fisher AJ, Presson RG Jr, Chiyo M, Lee J, Mickler E, Smith GN, Petrache I, Brand DB, Burlingham WJ, Gopalakrishnan B, Greenspan DS, Christie JD, Wilkes DS.

J Immunol. 2008 Oct 15;181(8):5738-47.PMID: 18832733 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeted induction of lung endothelial cell apoptosis causes emphysema-like changes in the mouse.

Giordano RJ, Lahdenranta J, Zhen L, Chukwueke U, Petrache I, Langley RR, Fidler IJ, Pasqualini R, Tuder RM, Arap W.

J Biol Chem. 2008 Oct 24;283(43):29447-60. Epub 2008 Aug 21.PMID: 18718906 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue transglutaminase protects epithelial ovarian cancer cells from cisplatin-induced apoptosis by promoting cell survival signaling.

Cao L, Petrusca DN, Satpathy M, Nakshatri H, Petrache I, Matei D.

Carcinogenesis. 2008 Oct;29(10):1893-900. Epub 2008 Jul 29.PMID: 18667446 [PubMed - indexed for MEDLINE]Related articlesFree article

HIV associated pulmonary emphysema: a review of the literature and inquiry into its mechanism.

Petrache I, Diab K, Knox KS, Twigg HL 3rd, Stephens RS, Flores S, Tuder RM.

Thorax. 2008 May;63(5):463-9. Review.PMID: 18443163 [PubMed - indexed for MEDLINE]Related articles

Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide.

Petrache I, Medler TR, Richter AT, Kamocki K, Chukwueke U, Zhen L, Gu Y, Adamowicz J, Schweitzer KS, Hubbard WC, Berdyshev EV, Lungarella G, Tuder RM.

Am J Physiol Lung Cell Mol Physiol. 2008 Jul;295(1):L44-53. Epub 2008 Apr 25.PMID: 18441093 [PubMed - indexed for MEDLINE]Related articlesFree article

Apoptotic sphingolipid signaling by ceramides in lung endothelial cells.

Medler TR, Petrusca DN, Lee PJ, Hubbard WC, Berdyshev EV, Skirball J, Kamocki K, Schuchman E, Tuder RM, Petrache I.

Am J Respir Cell Mol Biol. 2008 Jun;38(6):639-46. Epub 2008 Jan 10.PMID: 18192502 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular multitasking in the airspace: alpha1-antitrypsin takes on thrombin and plasmin.

Tuder RM, Petrache I.

Am J Respir Cell Mol Biol. 2007 Aug;37(2):130-4. Epub 2007 May 31. No abstract available. PMID: 17541009 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of lung maintenance program in the heterogeneity of lung destruction in emphysema.

Tuder RM, Yoshida T, Fijalkowka I, Biswal S, Petrache I.

Proc Am Thorac Soc. 2006 Nov;3(8):673-9. Review.PMID: 17065372 [PubMed - indexed for MEDLINE]Related articlesFree article

alpha-1 antitrypsin inhibits caspase-3 activity, preventing lung endothelial cell apoptosis.

Petrache I, Fijalkowska I, Medler TR, Skirball J, Cruz P, Zhen L, Petrache HI, Flotte TR, Tuder RM.

Am J Pathol. 2006 Oct;169(4):1155-66.PMID: 17003475 [PubMed - indexed for MEDLINE]Related articlesFree article

Ceramide causes pulmonary cell apoptosis and emphysema: a role for sphingolipid homeostasis in the maintenance of alveolar cells.

Petrache I, Natarajan V, Zhen L, Medler TR, Richter A, Berdyshev EV, Tuder RM.

Proc Am Thorac Soc. 2006 Aug;3(6):510. No abstract available. PMID: 16921130 [PubMed - indexed for MEDLINE]Related articlesFree article

State of the art. Cellular and molecular mechanisms of alveolar destruction in emphysema: an evolutionary perspective.

Tuder RM, Yoshida T, Arap W, Pasqualini R, Petrache I.

Proc Am Thorac Soc. 2006 Aug;3(6):503-10. Review.PMID: 16921129 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel antiapoptotic role for alpha1-antitrypsin in the prevention of pulmonary emphysema.

Petrache I, Fijalkowska I, Zhen L, Medler TR, Brown E, Cruz P, Choe KH, Taraseviciene-Stewart L, Scerbavicius R, Shapiro L, Zhang B, Song S, Hicklin D, Voelkel NF, Flotte T, Tuder RM.

Am J Respir Crit Care Med. 2006 Jun 1;173(11):1222-8. Epub 2006 Mar 2.PMID: 16514110 [PubMed - indexed for MEDLINE]Related articlesFree article

Pulmonary ischemia induces lung remodeling and angiogenesis.

Wagner EM, Petrache I, Schofield B, Mitzner W.

J Appl Physiol. 2006 Feb;100(2):587-93. Epub 2005 Oct 6.PMID: 16210444 [PubMed - indexed for MEDLINE]Related articlesFree article

Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice.

Petrache I, Natarajan V, Zhen L, Medler TR, Richter AT, Cho C, Hubbard WC, Berdyshev EV, Tuder RM.

Nat Med. 2005 May;11(5):491-8. Epub 2005 Apr 24.PMID: 15852018 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice.

Rangasamy T, Cho CY, Thimmulappa RK, Zhen L, Srisuma SS, Kensler TW, Yamamoto M, Petrache I, Tuder RM, Biswal S.

J Clin Invest. 2004 Nov;114(9):1248-59.PMID: 15520857 [PubMed - indexed for MEDLINE]Related articlesFree article

Central involvement of Rho family GTPases in TNF-alpha-mediated bovine pulmonary endothelial cell apoptosis.

Petrache I, Crow MT, Neuss M, Garcia JG.

Biochem Biophys Res Commun. 2003 Jun 20;306(1):244-9.PMID: 12788095 [PubMed - indexed for MEDLINE]Related articles

The role of the microtubules in tumor necrosis factor-alpha-induced endothelial cell permeability.

Petrache I, Birukova A, Ramirez SI, Garcia JG, Verin AD.

Am J Respir Cell Mol Biol. 2003 May;28(5):574-81.PMID: 12707013 [PubMed - indexed for MEDLINE]Related articlesFree article

Apoptosis and emphysema: the missing link.

Tuder RM, Petrache I, Elias JA, Voelkel NF, Henson PM.

Am J Respir Cell Mol Biol. 2003 May;28(5):551-4. No abstract available. PMID: 12707010 [PubMed - indexed for MEDLINE]Related articlesFree article

Caspase-dependent cleavage of myosin light chain kinase (MLCK) is involved in TNF-alpha-mediated bovine pulmonary endothelial cell apoptosis.

Petrache I, Birukov K, Zaiman AL, Crow MT, Deng H, Wadgaonkar R, Romer LH, Garcia JG.

FASEB J. 2003 Mar;17(3):407-16.PMID: 12631580 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effect of MLC kinase in TNF-alpha-induced endothelial cell apoptosis and barrier dysfunction.

Petrache I, Verin AD, Crow MT, Birukova A, Liu F, Garcia JG.

Am J Physiol Lung Cell Mol Physiol. 2001 Jun;280(6):L1168-78.PMID: 11350795 [PubMed - indexed for MEDLINE]Related articlesFree article

Heme oxygenase-1 inhibits TNF-alpha-induced apoptosis in cultured fibroblasts.

Petrache I, Otterbein LE, Alam J, Wiegand GW, Choi AM.

Am J Physiol Lung Cell Mol Physiol. 2000 Feb;278(2):L312-9.PMID: 10666115 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitogen-activated protein kinase pathway mediates hyperoxia-induced apoptosis in cultured macrophage cells.

Petrache I, Choi ME, Otterbein LE, Chin BY, Mantell LL, Horowitz S, Choi AM.

Am J Physiol. 1999 Sep;277(3 Pt 1):L589-95.PMID: 10484467 [PubMed - indexed for MEDLINE]Related articlesFree article

Protective effects of heme oxygenase-1 in acute lung injury.

Otterbein LE, Lee PJ, Chin BY, Petrache I, Camhi SL, Alam J, Choi AM.

Chest. 1999 Jul;116(1 Suppl):61S-63S. No abstract available. PMID: 10424595 [PubMed - indexed for MEDLINE]Related articlesFree article

Transforming growth factor beta1 rescues serum deprivation-induced apoptosis via the mitogen-activated protein kinase (MAPK) pathway in macrophages.

Chin BY, Petrache I, Choi AM, Choi ME.

J Biol Chem. 1999 Apr 16;274(16):11362-8.PMID: 10196228 [PubMed - indexed for MEDLINE]Related articlesFree article