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    Results: 1 to 50 of 130

    1.

    Altered brain mitochondrial metabolism in healthy aging as assessed by in vivo magnetic resonance spectroscopy.

    Boumezbeur F, Mason GF, de Graaf RA, Behar KL, Cline GW, Shulman GI, Rothman DL, Petersen KF.

    J Cereb Blood Flow Metab. 2009 Sep 30. [Epub ahead of print]PMID: 19794401 [PubMed - as supplied by publisher]Related articles

    2.

    Regulation of net hepatic glycogenolysis and gluconeogenesis by epinephrine in humans.

    Dufour S, Lebon V, Shulman GI, Petersen KF.

    Am J Physiol Endocrinol Metab. 2009 Jul;297(1):E231-5. Epub 2009 May 19.PMID: 19458062 [PubMed - indexed for MEDLINE]Related articles

    3.

    Paradoxical effects of increased expression of PGC-1alpha on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism.

    Choi CS, Befroy DE, Codella R, Kim S, Reznick RM, Hwang YJ, Liu ZX, Lee HY, Distefano A, Samuel VT, Zhang D, Cline GW, Handschin C, Lin J, Petersen KF, Spiegelman BM, Shulman GI.

    Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19926-31. Epub 2008 Dec 9.PMID: 19066218 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Increased substrate oxidation and mitochondrial uncoupling in skeletal muscle of endurance-trained individuals.

    Befroy DE, Petersen KF, Dufour S, Mason GF, Rothman DL, Shulman GI.

    Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16701-6. Epub 2008 Oct 20.PMID: 18936488 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Comparative MR study of hepatic fat quantification using single-voxel proton spectroscopy, two-point dixon and three-point IDEAL.

    Kim H, Taksali SE, Dufour S, Befroy D, Goodman TR, Petersen KF, Shulman GI, Caprio S, Constable RT.

    Magn Reson Med. 2008 Mar;59(3):521-7.PMID: 18306404 [PubMed - indexed for MEDLINE]Related articles

    6.

    Increased hypothalamic-pituitary-adrenal axis activity and hepatic insulin resistance in low-birth-weight rats.

    Buhl ES, Neschen S, Yonemitsu S, Rossbacher J, Zhang D, Morino K, Flyvbjerg A, Perret P, Samuel V, Kim J, Cline GW, Petersen KF.

    Am J Physiol Endocrinol Metab. 2007 Nov;293(5):E1451-8. Epub 2007 Sep 25.PMID: 17895287 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome.

    Petersen KF, Dufour S, Savage DB, Bilz S, Solomon G, Yonemitsu S, Cline GW, Befroy D, Zemany L, Kahn BB, Papademetris X, Rothman DL, Shulman GI.

    Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12587-94. Epub 2007 Jul 18.PMID: 17640906 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Disordered lipid metabolism and the pathogenesis of insulin resistance.

    Savage DB, Petersen KF, Shulman GI.

    Physiol Rev. 2007 Apr;87(2):507-20. Review.PMID: 17429039 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients.

    Befroy DE, Petersen KF, Dufour S, Mason GF, de Graaf RA, Rothman DL, Shulman GI.

    Diabetes. 2007 May;56(5):1376-81. Epub 2007 Feb 7.PMID: 17287462 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction.

    Morino K, Petersen KF, Shulman GI.

    Diabetes. 2006 Dec;55 Suppl 2:S9-S15. Review.PMID: 17130651 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian-Indian men.

    Petersen KF, Dufour S, Feng J, Befroy D, Dziura J, Dalla Man C, Cobelli C, Shulman GI.

    Proc Natl Acad Sci U S A. 2006 Nov 28;103(48):18273-7. Epub 2006 Nov 17.PMID: 17114290 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Measurements of the anaplerotic rate in the human cerebral cortex using 13C magnetic resonance spectroscopy and [1-13C] and [2-13C] glucose.

    Mason GF, Petersen KF, de Graaf RA, Shulman GI, Rothman DL.

    J Neurochem. 2007 Jan;100(1):73-86. Epub 2006 Oct 31.PMID: 17076763 [PubMed - indexed for MEDLINE]Related articles

    13.

    A randomized controlled study of effects of dietary magnesium oxide supplementation on bone mineral content in healthy girls.

    Carpenter TO, DeLucia MC, Zhang JH, Bejnerowicz G, Tartamella L, Dziura J, Petersen KF, Befroy D, Cohen D.

    J Clin Endocrinol Metab. 2006 Dec;91(12):4866-72. Epub 2006 Oct 3.PMID: 17018656 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    New insights into the pathogenesis of insulin resistance in humans using magnetic resonance spectroscopy.

    Petersen KF, Shulman GI.

    Obesity (Silver Spring). 2006 Feb;14 Suppl 1:34S-40S. Review.PMID: 16642961 [PubMed - indexed for MEDLINE]Related articles

    15.

    Increased brain monocarboxylic acid transport and utilization in type 1 diabetes.

    Mason GF, Petersen KF, Lebon V, Rothman DL, Shulman GI.

    Diabetes. 2006 Apr;55(4):929-34.PMID: 16567513 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Etiology of insulin resistance.

    Petersen KF, Shulman GI.

    Am J Med. 2006 May;119(5 Suppl 1):S10-6. Review.PMID: 16563942 [PubMed - indexed for MEDLINE]Related articles

    17.

    Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents.

    Morino K, Petersen KF, Dufour S, Befroy D, Frattini J, Shatzkes N, Neschen S, White MF, Bilz S, Sono S, Pypaert M, Shulman GI.

    J Clin Invest. 2005 Dec;115(12):3587-93. Epub 2005 Nov 10.PMID: 16284649 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Decreased insulin-stimulated ATP synthesis and phosphate transport in muscle of insulin-resistant offspring of type 2 diabetic parents.

    Petersen KF, Dufour S, Shulman GI.

    PLoS Med. 2005 Sep;2(9):e233. Epub 2005 Aug 16.PMID: 16089501 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Mitochondrial dysfunction and type 2 diabetes.

    Parish R, Petersen KF.

    Curr Diab Rep. 2005 Jun;5(3):177-83. Review.PMID: 15929863 [PubMed - indexed for MEDLINE]Related articles

    20.

    Mechanisms of insulin resistance in humans and possible links with inflammation.

    Savage DB, Petersen KF, Shulman GI.

    Hypertension. 2005 May;45(5):828-33. Epub 2005 Apr 11. Review.PMID: 15824195 [PubMed - indexed for MEDLINE]Related articlesFree article

    21.

    Reversal of nonalcoholic hepatic steatosis, hepatic insulin resistance, and hyperglycemia by moderate weight reduction in patients with type 2 diabetes.

    Petersen KF, Dufour S, Befroy D, Lehrke M, Hendler RE, Shulman GI.

    Diabetes. 2005 Mar;54(3):603-8.PMID: 15734833 [PubMed - indexed for MEDLINE]Related articlesFree article

    22.

    A cluster of metabolic defects caused by mutation in a mitochondrial tRNA.

    Wilson FH, Hariri A, Farhi A, Zhao H, Petersen KF, Toka HR, Nelson-Williams C, Raja KM, Kashgarian M, Shulman GI, Scheinman SJ, Lifton RP.

    Science. 2004 Nov 12;306(5699):1190-4. Epub 2004 Oct 21.PMID: 15498972 [PubMed - indexed for MEDLINE]Related articlesFree article

    23.

    Regulation of net hepatic glycogenolysis and gluconeogenesis during exercise: impact of type 1 diabetes.

    Petersen KF, Price TB, Bergeron R.

    J Clin Endocrinol Metab. 2004 Sep;89(9):4656-64.PMID: 15356077 [PubMed - indexed for MEDLINE]Related articlesFree article

    24.

    Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes.

    Petersen KF, Dufour S, Befroy D, Garcia R, Shulman GI.

    N Engl J Med. 2004 Feb 12;350(7):664-71.PMID: 14960743 [PubMed - indexed for MEDLINE]Related articlesFree article

    25.

    Prediabetes in obese youth: a syndrome of impaired glucose tolerance, severe insulin resistance, and altered myocellular and abdominal fat partitioning.

    Weiss R, Dufour S, Taksali SE, Tamborlane WV, Petersen KF, Bonadonna RC, Boselli L, Barbetta G, Allen K, Rife F, Savoye M, Dziura J, Sherwin R, Shulman GI, Caprio S.

    Lancet. 2003 Sep 20;362(9388):951-7.PMID: 14511928 [PubMed - indexed for MEDLINE]Related articles

    26.

    Effects of depletion exercise and light training on muscle glycogen supercompensation in men.

    Goforth HW Jr, Laurent D, Prusaczyk WK, Schneider KE, Petersen KF, Shulman GI.

    Am J Physiol Endocrinol Metab. 2003 Dec;285(6):E1304-11. Epub 2003 Aug 5.PMID: 12902321 [PubMed - indexed for MEDLINE]Related articlesFree article

    27.

    13C/31P NMR studies on the role of glucose transport/phosphorylation in human glycogen supercompensation.

    Price TB, Laurent D, Petersen KF.

    Int J Sports Med. 2003 May;24(4):238-44.PMID: 12784164 [PubMed - indexed for MEDLINE]Related articles

    28.

    Mitochondrial dysfunction in the elderly: possible role in insulin resistance.

    Petersen KF, Befroy D, Dufour S, Dziura J, Ariyan C, Rothman DL, DiPietro L, Cline GW, Shulman GI.

    Science. 2003 May 16;300(5622):1140-2.PMID: 12750520 [PubMed - indexed for MEDLINE]Related articlesFree article

    29.

    Pathogenesis of skeletal muscle insulin resistance in type 2 diabetes mellitus.

    Petersen KF, Shulman GI.

    Am J Cardiol. 2002 Sep 5;90(5A):11G-18G. Review.PMID: 12231074 [PubMed - indexed for MEDLINE]Related articles

    30.

    Cellular mechanism of insulin resistance in skeletal muscle.

    Petersen KF, Shulman GI.

    J R Soc Med. 2002;95 Suppl 42:8-13. No abstract available. PMID: 12216329 [PubMed - indexed for MEDLINE]Related articlesFree article

    31.

    Nonalcoholic fatty liver disease.

    Inzucchi SE, Petersen KF, Shulman GI.

    N Engl J Med. 2002 Sep 5;347(10):768-9; author reply 768-9. No abstract available. PMID: 12214631 [PubMed - indexed for MEDLINE]Related articles

    32.

    [2,4-13 C2 ]-beta-Hydroxybutyrate metabolism in human brain.

    Pan JW, de Graaf RA, Petersen KF, Shulman GI, Hetherington HP, Rothman DL.

    J Cereb Blood Flow Metab. 2002 Jul;22(7):890-8.PMID: 12142574 [PubMed - indexed for MEDLINE]Related articlesFree article

    33.

    Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy.

    Petersen KF, Oral EA, Dufour S, Befroy D, Ariyan C, Yu C, Cline GW, DePaoli AM, Taylor SI, Gorden P, Shulman GI.

    J Clin Invest. 2002 May;109(10):1345-50.PMID: 12021250 [PubMed - indexed for MEDLINE]Related articlesFree article

    34.

    Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes.

    Hundal RS, Petersen KF, Mayerson AB, Randhawa PS, Inzucchi S, Shoelson SE, Shulman GI.

    J Clin Invest. 2002 May;109(10):1321-6.PMID: 12021247 [PubMed - indexed for MEDLINE]Related articlesFree article

    35.

    Assessment of skeletal muscle triglyceride content by (1)H nuclear magnetic resonance spectroscopy in lean and obese adolescents: relationships to insulin sensitivity, total body fat, and central adiposity.

    Sinha R, Dufour S, Petersen KF, LeBon V, Enoksson S, Ma YZ, Savoye M, Rothman DL, Shulman GI, Caprio S.

    Diabetes. 2002 Apr;51(4):1022-7.PMID: 11916921 [PubMed - indexed for MEDLINE]Related articlesFree article

    36.

    Astroglial contribution to brain energy metabolism in humans revealed by 13C nuclear magnetic resonance spectroscopy: elucidation of the dominant pathway for neurotransmitter glutamate repletion and measurement of astrocytic oxidative metabolism.

    Lebon V, Petersen KF, Cline GW, Shen J, Mason GF, Dufour S, Behar KL, Shulman GI, Rothman DL.

    J Neurosci. 2002 Mar 1;22(5):1523-31.PMID: 11880482 [PubMed - indexed for MEDLINE]Related articlesFree article

    37.

    The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes.

    Mayerson AB, Hundal RS, Dufour S, Lebon V, Befroy D, Cline GW, Enocksson S, Inzucchi SE, Shulman GI, Petersen KF.

    Diabetes. 2002 Mar;51(3):797-802.PMID: 11872682 [PubMed - indexed for MEDLINE]Related articlesFree article

    38.

    Contrasting effects of fish oil and safflower oil on hepatic peroxisomal and tissue lipid content.

    Neschen S, Moore I, Regittnig W, Yu CL, Wang Y, Pypaert M, Petersen KF, Shulman GI.

    Am J Physiol Endocrinol Metab. 2002 Feb;282(2):E395-401.PMID: 11788372 [PubMed - indexed for MEDLINE]Related articlesFree article

    39.

    Effects of a novel glucagon receptor antagonist (Bay 27-9955) on glucagon-stimulated glucose production in humans.

    Petersen KF, Sullivan JT.

    Diabetologia. 2001 Nov;44(11):2018-24.PMID: 11719833 [PubMed - indexed for MEDLINE]Related articles

    40.

    Effect of triiodothyronine on mitochondrial energy coupling in human skeletal muscle.

    Lebon V, Dufour S, Petersen KF, Ren J, Jucker BM, Slezak LA, Cline GW, Rothman DL, Shulman GI.

    J Clin Invest. 2001 Sep;108(5):733-7.PMID: 11544279 [PubMed - indexed for MEDLINE]Related articlesFree article

    41.

    Stimulating effects of low-dose fructose on insulin-stimulated hepatic glycogen synthesis in humans.

    Petersen KF, Laurent D, Yu C, Cline GW, Shulman GI.

    Diabetes. 2001 Jun;50(6):1263-8.PMID: 11375325 [PubMed - indexed for MEDLINE]Related articlesFree article

    42.

    Contribution of net hepatic glycogen synthesis to disposal of an oral glucose load in humans.

    Petersen KF, Cline GW, Gerard DP, Magnusson I, Rothman DL, Shulman GI.

    Metabolism. 2001 May;50(5):598-601.PMID: 11319724 [PubMed - indexed for MEDLINE]Related articles

    43.

    Nuclear magnetic resonance studies of hepatic glucose metabolism in humans.

    Roden M, Petersen KF, Shulman GI.

    Recent Prog Horm Res. 2001;56:219-37. Review.PMID: 11237214 [PubMed - indexed for MEDLINE]Related articlesFree article

    44.

    Legal implications of lay use of automatic external defibrillators in non-hospital settings.

    Petersen KF.

    J Contemp Health Law Policy. 2000 Winter;17(1):275-320. No abstract available. PMID: 11216341 [PubMed - indexed for MEDLINE]Related articles

    45.

    Mechanism by which metformin reduces glucose production in type 2 diabetes.

    Hundal RS, Krssak M, Dufour S, Laurent D, Lebon V, Chandramouli V, Inzucchi SE, Schumann WC, Petersen KF, Landau BR, Shulman GI.

    Diabetes. 2000 Dec;49(12):2063-9.PMID: 11118008 [PubMed - indexed for MEDLINE]Related articlesFree article

    46.

    Mechanism of troglitazone action in type 2 diabetes.

    Petersen KF, Krssak M, Inzucchi S, Cline GW, Dufour S, Shulman GI.

    Diabetes. 2000 May;49(5):827-31.PMID: 10905493 [PubMed - indexed for MEDLINE]Related articlesFree article

    47.

    Effects of caffeine on muscle glycogen utilization and the neuroendocrine axis during exercise.

    Laurent D, Schneider KE, Prusaczyk WK, Franklin C, Vogel SM, Krssak M, Petersen KF, Goforth HW, Shulman GI.

    J Clin Endocrinol Metab. 2000 Jun;85(6):2170-5.PMID: 10852448 [PubMed - indexed for MEDLINE]Related articlesFree article

    48.

    Mechanism of muscle glycogen autoregulation in humans.

    Laurent D, Hundal RS, Dresner A, Price TB, Vogel SM, Petersen KF, Shulman GI.

    Am J Physiol Endocrinol Metab. 2000 Apr;278(4):E663-8.PMID: 10751200 [PubMed - indexed for MEDLINE]Related articlesFree article

    49.

    Intramuscular glycogen and intramyocellular lipid utilization during prolonged exercise and recovery in man: a 13C and 1H nuclear magnetic resonance spectroscopy study.

    Krssak M, Petersen KF, Bergeron R, Price T, Laurent D, Rothman DL, Roden M, Shulman GI.

    J Clin Endocrinol Metab. 2000 Feb;85(2):748-54.PMID: 10690886 [PubMed - indexed for MEDLINE]Related articlesFree article

    50.

    Glycogen loading alters muscle glycogen resynthesis after exercise.

    Price TB, Laurent D, Petersen KF, Rothman DL, Shulman GI.

    J Appl Physiol. 2000 Feb;88(2):698-704.PMID: 10658040 [PubMed - indexed for MEDLINE]Related articlesFree article

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