PubMed

Single-cell RT-PCR identification of genes expressed by human islet endocrine cells.

Muller D, Jones PM, Persaud SJ.

Methods Mol Biol. 2009;560:73-86.PMID: 19504245 [PubMed - in process]Related articles

Characterisation of the insulinotropic activity of an aqueous extract of Gymnema sylvestre in mouse beta-cells and human islets of Langerhans.

Liu B, Asare-Anane H, Al-Romaiyan A, Huang G, Amiel SA, Jones PM, Persaud SJ.

Cell Physiol Biochem. 2009;23(1-3):125-32. Epub 2009 Feb 18.PMID: 19255507 [PubMed - indexed for MEDLINE]Related articles

Kisspeptin stimulation of insulin secretion: mechanisms of action in mouse islets and rats.

Bowe JE, King AJ, Kinsey-Jones JS, Foot VL, Li XF, O'Byrne KT, Persaud SJ, Jones PM.

Diabetologia. 2009 May;52(5):855-62. Epub 2009 Feb 17.PMID: 19221709 [PubMed - indexed for MEDLINE]Related articles

A role for the extracellular calcium-sensing receptor in cell-cell communication in pancreatic islets of langerhans.

Kitsou-Mylona I, Burns CJ, Squires PE, Persaud SJ, Jones PM.

Cell Physiol Biochem. 2008;22(5-6):557-66. Epub 2008 Dec 9.PMID: 19088438 [PubMed - indexed for MEDLINE]Related articles

Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice.

Cantley J, Selman C, Shukla D, Abramov AY, Forstreuter F, Esteban MA, Claret M, Lingard SJ, Clements M, Harten SK, Asare-Anane H, Batterham RL, Herrera PL, Persaud SJ, Duchen MR, Maxwell PH, Withers DJ.

J Clin Invest. 2009 Jan;119(1):125-35. doi: 10.1172/JCI26934. Epub 2008 Dec 8.PMID: 19065050 [PubMed - indexed for MEDLINE]Related articlesFree article

Somatostatin secreted by islet delta-cells fulfills multiple roles as a paracrine regulator of islet function.

Hauge-Evans AC, King AJ, Carmignac D, Richardson CC, Robinson IC, Low MJ, Christie MR, Persaud SJ, Jones PM.

Diabetes. 2009 Feb;58(2):403-11. Epub 2008 Nov 4.PMID: 18984743 [PubMed - indexed for MEDLINE]Related articlesFree article

Islet neogenesis-associated protein signaling in neonatal pancreatic rat islets: involvement of the cholinergic pathway.

Barbosa HC, Bordin S, Anhê G, Persaud SJ, Bowe J, Borelli MI, Gagliardino JJ, Boschero AC.

J Endocrinol. 2008 Nov;199(2):299-306. Epub 2008 Sep 4.PMID: 18772167 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell-based treatments for diabetes.

Jones PM, Courtney ML, Burns CJ, Persaud SJ.

Drug Discov Today. 2008 Oct;13(19-20):888-93. Epub 2008 Aug 4. Review.PMID: 18652911 [PubMed - indexed for MEDLINE]Related articles

Insulin signalling in islets.

Persaud SJ, Muller D, Jones PM.

Biochem Soc Trans. 2008 Jun;36(Pt 3):290-3.PMID: 18481944 [PubMed - indexed for MEDLINE]Related articles

Diabetes mellitus: a potential target for stem cell therapy.

Burns CJ, Persaud SJ, Jones PM.

Curr Stem Cell Res Ther. 2006 May;1(2):255-66. Review.PMID: 18220871 [PubMed - indexed for MEDLINE]Related articles

Function and expression of melatonin receptors on human pancreatic islets.

Ramracheya RD, Muller DS, Squires PE, Brereton H, Sugden D, Huang GC, Amiel SA, Jones PM, Persaud SJ.

J Pineal Res. 2008 Apr;44(3):273-9. Epub 2008 Jan 9.PMID: 18194202 [PubMed - indexed for MEDLINE]Related articles

Expression and function of the extracellular calcium-sensing receptor in pancreatic beta-cells.

Jones PM, Kitsou-Mylona I, Gray E, Squires PE, Persaud SJ.

Arch Physiol Biochem. 2007 Jun;113(3):98-103.PMID: 17852049 [PubMed - indexed for MEDLINE]Related articles

Expression and function of cyclooxygenase and lipoxygenase enzymes in human islets of Langerhans.

Persaud SJ, Muller D, Belin VD, Papadimitriou A, Huang GC, Amiel SA, Jones PM.

Arch Physiol Biochem. 2007 Jun;113(3):104-9. Review.PMID: 17852048 [PubMed - indexed for MEDLINE]Related articles

E-cadherin interactions regulate beta-cell proliferation in islet-like structures.

Carvell MJ, Marsh PJ, Persaud SJ, Jones PM.

Cell Physiol Biochem. 2007;20(5):617-26.PMID: 17762188 [PubMed - indexed for MEDLINE]Related articles

Anti-apoptotic effects of arachidonic acid and prostaglandin E2 in pancreatic beta-cells.

Papadimitriou A, King AJ, Jones PM, Persaud SJ.

Cell Physiol Biochem. 2007;20(5):607-16.PMID: 17762187 [PubMed - indexed for MEDLINE]Related articles

Islet alpha-cells do not influence insulin secretion from beta-cells through cell-cell contact.

Brereton H, Carvell MJ, Persaud SJ, Jones PM.

Endocrine. 2007 Feb;31(1):61-5.PMID: 17709899 [PubMed - indexed for MEDLINE]Related articles

Gene expression heterogeneity in human islet endocrine cells in vitro: the insulin signalling cascade.

Muller D, Huang GC, Amiel S, Jones PM, Persaud SJ.

Diabetologia. 2007 Jun;50(6):1239-42. Epub 2007 Apr 18.PMID: 17440705 [PubMed - indexed for MEDLINE]Related articles

Pancreatic deletion of insulin receptor substrate 2 reduces beta and alpha cell mass and impairs glucose homeostasis in mice.

Cantley J, Choudhury AI, Asare-Anane H, Selman C, Lingard S, Heffron H, Herrera P, Persaud SJ, Withers DJ.

Diabetologia. 2007 Jun;50(6):1248-56. Epub 2007 Mar 29.PMID: 17393136 [PubMed - indexed for MEDLINE]Related articles

Pancreatic duodenal homeobox 1 expression is insufficient to transdifferentiate liver cells into insulin-secreting cells.

Wu Y, Minger SL, Sawyer GJ, Fabre JW, Persaud SJ, Jones PM.

Pancreas. 2007 Mar;34(2):272-5. No abstract available. PMID: 17312471 [PubMed - indexed for MEDLINE]Related articles

The role of arachidonic acid and its metabolites in insulin secretion from human islets of langerhans.

Persaud SJ, Muller D, Belin VD, Kitsou-Mylona I, Asare-Anane H, Papadimitriou A, Burns CJ, Huang GC, Amiel SA, Jones PM.

Diabetes. 2007 Jan;56(1):197-203.PMID: 17192482 [PubMed - indexed for MEDLINE]Related articlesFree article

Autocrine anti-apoptotic and proliferative effects of insulin in pancreatic beta-cells.

Muller D, Jones PM, Persaud SJ.

FEBS Lett. 2006 Dec 22;580(30):6977-80. Epub 2006 Dec 4.PMID: 17161395 [PubMed - indexed for MEDLINE]Related articles

Identification of insulin signaling elements in human beta-cells: autocrine regulation of insulin gene expression.

Muller D, Huang GC, Amiel S, Jones PM, Persaud SJ.

Diabetes. 2006 Oct;55(10):2835-42.PMID: 17003350 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of the extracellular calcium-sensing receptor initiates insulin secretion from human islets of Langerhans: involvement of protein kinases.

Gray E, Muller D, Squires PE, Asare-Anane H, Huang GC, Amiel S, Persaud SJ, Jones PM.

J Endocrinol. 2006 Sep;190(3):703-10.PMID: 17003271 [PubMed - indexed for MEDLINE]Related articlesFree article

A role for kisspeptin in islet function.

Hauge-Evans AC, Richardson CC, Milne HM, Christie MR, Persaud SJ, Jones PM.

Diabetologia. 2006 Sep;49(9):2131-5. Epub 2006 Jul 7.PMID: 16826407 [PubMed - indexed for MEDLINE]Related articles

Homotypic cell contact enhances insulin but not glucagon secretion.

Brereton HC, Carvell MJ, Asare-Anane H, Roberts G, Christie MR, Persaud SJ, Jones PM.

Biochem Biophys Res Commun. 2006 Jun 9;344(3):995-1000. Epub 2006 Apr 19.PMID: 16643853 [PubMed - indexed for MEDLINE]Related articles

MIN6 beta-cell-beta-cell interactions influence insulin secretory responses to nutrients and non-nutrients.

Luther MJ, Hauge-Evans A, Souza KL, Jörns A, Lenzen S, Persaud SJ, Jones PM.

Biochem Biophys Res Commun. 2006 Apr 28;343(1):99-104. Epub 2006 Feb 10.PMID: 16529716 [PubMed - indexed for MEDLINE]Related articles

Direct regulation of insulin secretion by angiotensin II in human islets of Langerhans.

Ramracheya RD, Muller DS, Wu Y, Whitehouse BJ, Huang GC, Amiel SA, Karalliedde J, Viberti G, Jones PM, Persaud SJ.

Diabetologia. 2006 Feb;49(2):321-31. Epub 2006 Jan 17.PMID: 16416272 [PubMed - indexed for MEDLINE]Related articles

Effect of 17beta-estradiol on insulin secretion and cytosolic calcium in Min6 mouse insulinoma cells and human islets of Langerhans.

Al-Majed HT, Squires PE, Persaud SJ, Huang GC, Amiel S, Whitehouse BJ, Jones PM.

Pancreas. 2005 May;30(4):307-13.PMID: 15841038 [PubMed - indexed for MEDLINE]Related articles

Similarities of K+ATP channel expression and Ca2+ changes in pancreatic beta cells and hypothalamic neurons.

Squires PE, Churamani D, Pararajasingam R, Persaud SJ, Jones PM.

Pancreas. 2005 Apr;30(3):227-32.PMID: 15782099 [PubMed - indexed for MEDLINE]Related articles

Generation of insulin-expressing cells from mouse embryonic stem cells.

Milne HM, Burns CJ, Kitsou-Mylona I, Luther MJ, Minger SL, Persaud SJ, Jones PM.

Biochem Biophys Res Commun. 2005 Mar 11;328(2):399-403.PMID: 15694361 [PubMed - indexed for MEDLINE]Related articles

Uncoupling of nutrient metabolism from insulin secretion by overexpression of cytosolic phospholipase A(2).

Milne HM, Burns CJ, Squires PE, Evans ND, Pickup J, Jones PM, Persaud SJ.

Diabetes. 2005 Jan;54(1):116-24.PMID: 15616018 [PubMed - indexed for MEDLINE]Related articlesFree article

The in vitro differentiation of rat neural stem cells into an insulin-expressing phenotype.

Burns CJ, Minger SL, Hall S, Milne H, Ramracheya RD, Evans ND, Persaud SJ, Jones PM.

Biochem Biophys Res Commun. 2005 Jan 21;326(3):570-7.PMID: 15596137 [PubMed - indexed for MEDLINE]Related articles

Stem cell therapy for diabetes: do we need to make beta cells?

Burns CJ, Persaud SJ, Jones PM.

J Endocrinol. 2004 Dec;183(3):437-43.PMID: 15590970 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell-to-cell contact influences proliferative marker expression and apoptosis in MIN6 cells grown in islet-like structures.

Luther MJ, Davies E, Muller D, Harrison M, Bone AJ, Persaud SJ, Jones PM.

Am J Physiol Endocrinol Metab. 2005 Mar;288(3):E502-9. Epub 2004 Oct 12.PMID: 15479950 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired glucose homeostasis and mitochondrial abnormalities in offspring of rats fed a fat-rich diet in pregnancy.

Taylor PD, McConnell J, Khan IY, Holemans K, Lawrence KM, Asare-Anane H, Persaud SJ, Jones PM, Petrie L, Hanson MA, Poston L.

Am J Physiol Regul Integr Comp Physiol. 2005 Jan;288(1):R134-9. Epub 2004 Sep 23.PMID: 15388492 [PubMed - indexed for MEDLINE]Related articles

Glucose-induced regulation of COX-2 expression in human islets of Langerhans.

Persaud SJ, Burns CJ, Belin VD, Jones PM.

Diabetes. 2004 Feb;53 Suppl 1:S190-2.PMID: 14749287 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of cytosolic phospholipase A(2) in insulin secretion.

Jones PM, Burns CJ, Belin VD, Roderigo-Milne HM, Persaud SJ.

Diabetes. 2004 Feb;53 Suppl 1:S172-8.PMID: 14749284 [PubMed - indexed for MEDLINE]Related articlesFree article

ACTH stimulates insulin secretion from MIN6 cells and primary mouse and human islets of Langerhans.

Al-Majed HT, Jones PM, Persaud SJ, Sugden D, Huang GC, Amiel S, Whitehouse BJ.

J Endocrinol. 2004 Jan;180(1):155-66.PMID: 14709154 [PubMed - indexed for MEDLINE]Related articlesFree article

Calcium-dependent translocation of cytosolic phospholipase A2 in pancreatic beta-cells.

Persaud SJ, Jones PM, Roderigo-Milne HM, Buchan AM, Squires PE.

Biochem Biophys Res Commun. 2003 Jan 24;300(4):889-93.PMID: 12559956 [PubMed - indexed for MEDLINE]Related articles

Differential expression of insulin genes 1 and 2 in MIN6 cells and pseudoislets.

Roderigo-Milne H, Hauge-Evans AC, Persaud SJ, Jones PM.

Biochem Biophys Res Commun. 2002 Aug 23;296(3):589-95.PMID: 12176022 [PubMed - indexed for MEDLINE]Related articles

Co-ordinated Ca(2+)-signalling within pancreatic islets: does beta-cell entrainment require a secreted messenger.

Squires PE, Persaud SJ, Hauge-Evans AC, Gray E, Ratcliff H, Jones PM.

Cell Calcium. 2002 May;31(5):209-19.PMID: 12098223 [PubMed - indexed for MEDLINE]Related articles

Role of adenine nucleotides in insulin secretion from MIN6 pseudoislets.

Hauge-Evans AC, Squires PE, Belin VD, Roderigo-Milne H, Ramracheya RD, Persaud SJ, Jones PM.

Mol Cell Endocrinol. 2002 Jun 14;191(2):167-76.PMID: 12062900 [PubMed - indexed for MEDLINE]Related articles

Interdependence of steroidogenesis and shape changes in Y1 adrenocortical cells: studies with inhibitors of phosphoprotein phosphatases.

Whitehouse BJ, Gyles SL, Squires PE, Sayed SB, Burns CJ, Persaud SJ, Jones PM.

J Endocrinol. 2002 Mar;172(3):583-93.PMID: 11874707 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin receptor activation inhibits insulin secretion from human islets of Langerhans.

Persaud SJ, Asare-Anane H, Jones PM.

FEBS Lett. 2002 Jan 16;510(3):225-8.PMID: 11801259 [PubMed - indexed for MEDLINE]Related articles

A key role for beta-cell cytosolic phospholipase A(2) in the maintenance of insulin stores but not in the initiation of insulin secretion.

Persaud SJ, Roderigo-Milne HM, Squires PE, Sugden D, Wheeler-Jones CP, Marsh PJ, Belin VD, Luther MJ, Jones PM.

Diabetes. 2002 Jan;51(1):98-104.PMID: 11756328 [PubMed - indexed for MEDLINE]Related articlesFree article

ERKs regulate cyclic AMP-induced steroid synthesis through transcription of the steroidogenic acute regulatory (StAR) gene.

Gyles SL, Burns CJ, Whitehouse BJ, Sugden D, Marsh PJ, Persaud SJ, Jones PM.

J Biol Chem. 2001 Sep 14;276(37):34888-95. Epub 2001 Jun 15.PMID: 11410589 [PubMed - indexed for MEDLINE]Related articlesFree article

A role for the p42/44 isoforms of MAPK in the regulation of steroid secretion from Y1 mouse adrenocortical cells.

Gyles SL, Burns CJ, Persaud SJ, Jones PM, Whitehouse BJ.

Endocr Res. 2000 Nov;26(4):579-81. No abstract available. PMID: 11196432 [PubMed - indexed for MEDLINE]Related articles

The extracellular calcium-sensing receptor in PHHI beta cells: does reduced auto-inhibitory input contribute to hypersecretion of insulin?

Squires PE, Persaud SJ, Jones PM, Buchan AM.

Diabetologia. 2000 Aug;43(8):1078-80. No abstract available. PMID: 10990090 [PubMed - indexed for MEDLINE]Related articles

Phosphoprotein phosphatases regulate steroidogenesis by influencing StAR gene transcription.

Burns CJ, Gyles SL, Persaud SJ, Sugden D, Whitehouse BJ, Jones PM.

Biochem Biophys Res Commun. 2000 Jun 24;273(1):35-9.PMID: 10873559 [PubMed - indexed for MEDLINE]Related articles

The extracellular calcium-sensing receptor on human beta-cells negatively modulates insulin secretion.

Squires PE, Harris TE, Persaud SJ, Curtis SB, Buchan AM, Jones PM.

Diabetes. 2000 Mar;49(3):409-17.PMID: 10868962 [PubMed - indexed for MEDLINE]Related articlesFree article