PubMed

Target identification using drug affinity responsive target stability (DARTS).

Lomenick B, Hao R, Jonai N, Chin RM, Aghajan M, Warburton S, Wang J, Wu RP, Gomez F, Loo JA, Wohlschlegel JA, Vondriska TM, Pelletier J, Herschman HR, Clardy J, Clarke CF, Huang J.

Proc Natl Acad Sci U S A. 2009 Dec 7. [Epub ahead of print]PMID: 19995983 [PubMed - as supplied by publisher]Related articlesFree article

Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes.

Tardif G, Hum D, Pelletier JP, Duval N, Martel-Pelletier J.

BMC Musculoskelet Disord. 2009 Nov 30;10(1):148. [Epub ahead of print]PMID: 19948051 [PubMed - as supplied by publisher]Related articlesFree article

(1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methanamine: a wingless beta-catenin agonist that increases bone formation rate.

Pelletier JC, Lundquist JT 4th, Gilbert AM, Alon N, Bex FJ, Bhat BM, Bursavich MG, Coleburn VE, Felix LA, Green DM, Green P, Hauze DB, Kharode YP, Lam HS, Lockhead SR, Magolda RL, Matteo JJ, Mehlmann JF, Milligan C, Murrills RJ, Pirrello J, Selim S, Sharp MC, Unwalla RJ, Vera MD, Wrobel JE, Yaworsky P, Bodine PV.

J Med Chem. 2009 Nov 26;52(22):6962-5.PMID: 19856966 [PubMed - in process]Related articles

Olfactory proteins mediating chemical communication in the navel orangeworm moth, Amyelois transitella.

Leal WS, Ishida Y, Pelletier J, Xu W, Rayo J, Xu X, Ames JB.

PLoS One. 2009 Sep 30;4(9):e7235.PMID: 19789654 [PubMed - in process]Related articlesFree article

c-Myc and eIF4F constitute a feedforward loop that regulates cell growth: implications for anticancer therapy.

Lin CJ, Malina A, Pelletier J.

Cancer Res. 2009 Oct 1;69(19):7491-4. Epub 2009 Sep 22. Review.PMID: 19773439 [PubMed - indexed for MEDLINE]Related articles

Modulation of OPG, RANK and RANKL by human chondrocytes and their implication during osteoarthritis.

Kwan Tat S, Amiable N, Pelletier JP, Boileau C, Lajeunesse D, Duval N, Martel-Pelletier J.

Rheumatology (Oxford). 2009 Dec;48(12):1482-90. Epub 2009 Sep 17.PMID: 19762475 [PubMed - in process]Related articles

A combination povidone-iodine 0.4%/dexamethasone 0.1% ophthalmic suspension in the treatment of adenoviral conjunctivitis.

Pelletier JS, Stewart K, Trattler W, Ritterband DC, Braverman S, Samson CM, Liang B, Capriotti JA.

Adv Ther. 2009 Sep 7. [Epub ahead of print]PMID: 19756415 [PubMed - as supplied by publisher]Related articles

Synergistic effect of inhibiting translation initiation in combination with cytotoxic agents in acute myelogenous leukemia cells.

Cencic R, Carrier M, Trnkus A, Porco JA Jr, Minden M, Pelletier J.

Leuk Res. 2009 Sep 1. [Epub ahead of print]PMID: 19726085 [PubMed - as supplied by publisher]Related articles

Translation initiation: a critical signalling node in cancer.

Robert F, Pelletier J.

Expert Opin Ther Targets. 2009 Nov;13(11):1279-93.PMID: 19705976 [PubMed - in process]Related articles

Treatment with ephrin B2 positively impacts the abnormal metabolism of human osteoarthritic chondrocytes.

Kwan Tat S, Pelletier JP, Amiable N, Boileau C, Lavigne M, Martel-Pelletier J.

Arthritis Res Ther. 2009;11(4):R119. Epub 2009 Aug 7.PMID: 19664212 [PubMed - in process]Related articlesFree article

Fluorometric assay for tissue transglutaminase-mediated transamidation activity.

Gnaccarini C, Ben-Tahar W, Lubell WD, Pelletier JN, Keillor JW.

Bioorg Med Chem. 2009 Sep 1;17(17):6354-9. Epub 2009 Jul 18.PMID: 19660958 [PubMed - indexed for MEDLINE]Related articles

Burst firing induces postsynaptic LTD at developing mossy fibre-CA3 pyramid synapses.

Ho TM, Pelkey KA, Pelletier JG, Huganir RL, Lacaille JC, McBain CJ.

J Physiol. 2009 Sep 15;587(Pt 18):4441-54. Epub 2009 Jul 27.PMID: 19635819 [PubMed - indexed for MEDLINE]Related articles

Peptide Self-Assembled Monolayers for Label-Free and Unamplified Surface Plasmon Resonance Biosensing in Crude Cell Lysate.

Bolduc OR, Clouthier CM, Pelletier JN, Masson JF.

Anal Chem. 2009 Jul 16. [Epub ahead of print]PMID: 19606821 [PubMed - as supplied by publisher]Related articles

Genome analysis and expression patterns of odorant-binding proteins from the Southern House mosquito Culex pipiens quinquefasciatus.

Pelletier J, Leal WS.

PLoS One. 2009 Jul 16;4(7):e6237.PMID: 19606229 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between clinical conversion to multiple sclerosis in radiologically isolated syndrome and magnetic resonance imaging, cerebrospinal fluid, and visual evoked potential: follow-up of 70 patients.

Lebrun C, Bensa C, Debouverie M, Wiertlevski S, Brassat D, de Seze J, Rumbach L, Pelletier J, Labauge P, Brochet B, Tourbah A, Clavelou P; Club Francophone de la Sclérose en Plaques.

Arch Neurol. 2009 Jul;66(7):841-6.PMID: 19597085 [PubMed - indexed for MEDLINE]Related articles

Osteoarthritis: A single injection of anakinra for treating knee OA?

Martel-Pelletier J, Pelletier JP.

Nat Rev Rheumatol. 2009 Jul;5(7):363-4. No abstract available. PMID: 19568251 [PubMed - indexed for MEDLINE]Related articles

Oral treatment with a Brachystemma calycinum D. don plant extract reduces disease symptoms and the development of cartilage lesions in experimental dog osteoarthritis: inhibition of protease activated receptor-2 (PAR-2).

Boileau C, Martel-Pelletier J, Caron J, Paré F, Troncy E, Moreau M, Pelletier JP.

Ann Rheum Dis. 2009 Jun 21. [Epub ahead of print]PMID: 19546097 [PubMed - as supplied by publisher]Related articles

Heterogeneous nuclear ribonucleoprotein K represses the production of pro-apoptotic Bcl-xS splice isoform.

Revil T, Pelletier J, Toutant J, Cloutier A, Chabot B.

J Biol Chem. 2009 Aug 7;284(32):21458-67. Epub 2009 Jun 11.PMID: 19520842 [PubMed - indexed for MEDLINE]Related articles

Blocking UV-induced eIF2alpha phosphorylation with small molecule inhibitors of GCN2.

Robert F, Williams C, Yan Y, Donohue E, Cencic R, Burley SK, Pelletier J.

Chem Biol Drug Des. 2009 Jul;74(1):57-67.PMID: 19519745 [PubMed - indexed for MEDLINE]Related articles

Silibinin inhibits translation initiation: implications for anticancer therapy.

Lin CJ, Sukarieh R, Pelletier J.

Mol Cancer Ther. 2009 Jun;8(6):1606-12. Epub 2009 Jun 9.PMID: 19509268 [PubMed - indexed for MEDLINE]Related articles

Multiple conformers in active site of human dihydrofolate reductase F31R/Q35E double mutant suggest structural basis for methotrexate resistance.

Volpato JP, Yachnin BJ, Blanchet J, Guerrero V, Poulin L, Fossati E, Berghuis AM, Pelletier JN.

J Biol Chem. 2009 Jul 24;284(30):20079-89. Epub 2009 May 28.PMID: 19478082 [PubMed - indexed for MEDLINE]Related articles

Plasticity in MS: from Functional Imaging to Rehabilitation.

Pelletier J, Audoin B, Reuter F, Ranjeva J.

Int MS J. 2009 Apr;16(1):26-31.PMID: 19413923 [PubMed - in process]Related articlesFree article

Altering chemosensitivity by modulating translation elongation.

Robert F, Carrier M, Rawe S, Chen S, Lowe S, Pelletier J.

PLoS One. 2009;4(5):e5428. Epub 2009 May 1.PMID: 19412536 [PubMed - indexed for MEDLINE]Related articlesFree article

Altered mineralization of human osteoarthritic osteoblasts is attributable to abnormal type I collagen production.

Couchourel D, Aubry I, Delalandre A, Lavigne M, Martel-Pelletier J, Pelletier JP, Lajeunesse D.

Arthritis Rheum. 2009 May;60(5):1438-50.PMID: 19404930 [PubMed - indexed for MEDLINE]Related articles

Persistent transcription- and translation-dependent long-term potentiation induced by mGluR1 in hippocampal interneurons.

Ran I, Laplante I, Bourgeois C, Pépin J, Lacaille P, Costa-Mattioli M, Pelletier J, Sonenberg N, Lacaille JC.

J Neurosci. 2009 Apr 29;29(17):5605-15.PMID: 19403827 [PubMed - indexed for MEDLINE]Related articlesFree article

Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol.

Cencic R, Carrier M, Galicia-Vázquez G, Bordeleau ME, Sukarieh R, Bourdeau A, Brem B, Teodoro JG, Greger H, Tremblay ML, Porco JA Jr, Pelletier J.

PLoS One. 2009;4(4):e5223. Epub 2009 Apr 29.PMID: 19401772 [PubMed - indexed for MEDLINE]Related articlesFree article

New perspective in osteoarthritis: the OPG and RANKL system as a potential therapeutic target?

Tat SK, Pelletier JP, Velasco CR, Padrines M, Martel-Pelletier J.

Keio J Med. 2009 Mar;58(1):29-40. Review.PMID: 19398882 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of transcription in Staphylococcus aureus by a primary sigma factor-binding polypeptide from phage G1.

Dehbi M, Moeck G, Arhin FF, Bauda P, Bergeron D, Kwan T, Liu J, McCarty J, Dubow M, Pelletier J.

J Bacteriol. 2009 Jun;191(12):3763-71. Epub 2009 Apr 17.PMID: 19376864 [PubMed - indexed for MEDLINE]Related articlesFree article

Uncoupling stress granule assembly and translation initiation inhibition.

Mokas S, Mills JR, Garreau C, Fournier MJ, Robert F, Arya P, Kaufman RJ, Pelletier J, Mazroui R.

Mol Biol Cell. 2009 Jun;20(11):2673-83. Epub 2009 Apr 15.PMID: 19369421 [PubMed - indexed for MEDLINE]Related articlesFree article

[Cognitive impairment]

Reuter F, Audoin B, Rico A, Malikova I, Ranjeva JP, Pelletier J.

Rev Neurol (Paris). 2009 Mar;165 Suppl 4:S113-22. Review. French. PMID: 19361675 [PubMed - indexed for MEDLINE]Related articles

Activity-dependent compartmentalized regulation of dendritic Ca2+ signaling in hippocampal interneurons.

Topolnik L, Chamberland S, Pelletier JG, Ran I, Lacaille JC.

J Neurosci. 2009 Apr 8;29(14):4658-63.PMID: 19357290 [PubMed - indexed for MEDLINE]Related articlesFree article

Human articular chondrocytes express 15-lipoxygenase-1 and -2: potential role in osteoarthritis.

Chabane N, Zayed N, Benderdour M, Martel-Pelletier J, Pelletier JP, Duval N, Fahmi H.

Arthritis Res Ther. 2009;11(2):R44. Epub 2009 Mar 18.PMID: 19296842 [PubMed - indexed for MEDLINE]Related articlesFree article

Protective effects of total fraction of avocado/soybean unsaponifiables on the structural changes in experimental dog osteoarthritis: inhibition of nitric oxide synthase and matrix metalloproteinase-13.

Boileau C, Martel-Pelletier J, Caron J, Msika P, Guillou GB, Baudouin C, Pelletier JP.

Arthritis Res Ther. 2009;11(2):R41. Epub 2009 Mar 16.PMID: 19291317 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutational 'hot-spots' in mammalian, bacterial and protozoal dihydrofolate reductases associated with antifolate resistance: sequence and structural comparison.

Volpato JP, Pelletier JN.

Drug Resist Updat. 2009 Feb-Apr;12(1-2):28-41. Epub 2009 Mar 9. Review.PMID: 19272832 [PubMed - indexed for MEDLINE]Related articles

Photolabeling of tissue transglutaminase reveals the binding mode of potent cinnamoyl inhibitors.

Pardin C, Roy I, Chica RA, Bonneil E, Thibault P, Lubell WD, Pelletier JN, Keillor JW.

Biochemistry. 2009 Apr 21;48(15):3346-53.PMID: 19271761 [PubMed - indexed for MEDLINE]Related articles

Discovery of 6-({4-[2-(4-tert-butylphenyl)-1H-benzimidazol-4-yl]piperazin-1-yl}methyl)quinoxaline (WAY-207024): an orally active antagonist of the gonadotropin releasing hormone receptor (GnRH-R).

Pelletier JC, Chengalvala MV, Cottom JE, Feingold IB, Green DM, Hauze DB, Huselton CA, Jetter JW, Kopf GS, Lundquist JT, Magolda RL, Mann CW, Mehlmann JF, Rogers JF, Shanno LK, Adams WR, Tio CO, Wrobel JE.

J Med Chem. 2009 Apr 9;52(7):2148-52.PMID: 19271735 [PubMed - indexed for MEDLINE]Related articles

Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts.

Amiable N, Tat SK, Lajeunesse D, Duval N, Pelletier JP, Martel-Pelletier J, Boileau C.

Bone. 2009 Jun;44(6):1143-50. Epub 2009 Mar 2.PMID: 19264156 [PubMed - indexed for MEDLINE]Related articles

Small molecule antagonists of the gonadotropin-releasing hormone (GnRH) receptor: structure-activity relationships of small heterocyclic groups appended to the 2-phenyl-4-piperazinyl-benzimidazole template.

Hauze DB, Chengalvala MV, Cottom JE, Feingold IB, Garrick L, Green DM, Huselton C, Kao W, Kees K, Lundquist JT 4th, Mann CW, Mehlmann JF, Rogers JF, Shanno L, Wrobel J, Pelletier JC.

Bioorg Med Chem Lett. 2009 Apr 1;19(7):1986-90. Epub 2009 Feb 13.PMID: 19251413 [PubMed - indexed for MEDLINE]Related articles

The eIF4E-binding proteins are modifiers of cytoplasmic eIF4E relocalization during the heat shock response.

Sukarieh R, Sonenberg N, Pelletier J.

Am J Physiol Cell Physiol. 2009 May;296(5):C1207-17. Epub 2009 Feb 25.PMID: 19244480 [PubMed - indexed for MEDLINE]Related articles

Children's group nous: understanding and applying peer exclusion within and between groups.

Abrams D, Rutland A, Pelletier J, Ferrell JM.

Child Dev. 2009 Jan-Feb;80(1):224-43.PMID: 19236403 [PubMed - indexed for MEDLINE]Related articles

Quassinoid Inhibition of AP-1 Function Does Not Correlate with Cytotoxicity or Protein Synthesis Inhibition (dagger).

Beutler JA, Kang MI, Robert F, Clement JA, Pelletier J, Colburn NH, McKee TC, Goncharova E, McMahon JB, Henrich CJ.

J Nat Prod. 2009 Feb 6. [Epub ahead of print]PMID: 19199792 [PubMed - as supplied by publisher]Related articles

Imaging in osteoarthritis trials: useful or just expensive?

Pelletier JP, Martel-Pelletier J.

Nat Clin Pract Rheumatol. 2009 Feb;5(2):76-7. No abstract available. PMID: 19182813 [PubMed - indexed for MEDLINE]Related articles

High tolerance to simultaneous active-site mutations in TEM-1 beta-lactamase: Distinct mutational paths provide more generalized beta-lactam recognition.

De Wals PY, Doucet N, Pelletier JN.

Protein Sci. 2009 Jan;18(1):147-60.PMID: 19177359 [PubMed - indexed for MEDLINE]Related articles

Motor evoked potentials in clinically isolated syndrome suggestive of multiple sclerosis.

Rico A, Audoin B, Franques J, Eusebio A, Reuter F, Malikova I, Ali Cherif A, Pouget J, Pelletier J, Attarian S.

Mult Scler. 2009 Mar;15(3):355-62. Epub 2009 Jan 19.PMID: 19153175 [PubMed - indexed for MEDLINE]Related articles

Topical delivery of lipophilic drugs from o/w Pickering emulsions.

Frelichowska J, Bolzinger MA, Pelletier J, Valour JP, Chevalier Y.

Int J Pharm. 2009 Apr 17;371(1-2):56-63. Epub 2008 Dec 24.PMID: 19135516 [PubMed - indexed for MEDLINE]Related articles

Human hip joint cartilage: MRI quantitative thickness and volume measurements discriminating acetabulum and femoral head.

Li W, Abram F, Beaudoin G, Berthiaume MJ, Pelletier JP, Martel-Pelletier J.

IEEE Trans Biomed Eng. 2008 Dec;55(12):2731-40.PMID: 19126452 [PubMed - indexed for MEDLINE]Related articles

Localization of plasma membrane bound NTPDases in the murine reproductive tract.

Martín-Satué M, Lavoie EG, Pelletier J, Fausther M, Csizmadia E, Guckelberger O, Robson SC, Sévigny J.

Histochem Cell Biol. 2009 May;131(5):615-28. Epub 2009 Jan 6.PMID: 19125273 [PubMed - indexed for MEDLINE]Related articles

Characterization of a monoclonal antibody as the first specific inhibitor of human NTP diphosphohydrolase-3 : partial characterization of the inhibitory epitope and potential applications.

Munkonda MN, Pelletier J, Ivanenkov VV, Fausther M, Tremblay A, Künzli B, Kirley TL, Sévigny J.

FEBS J. 2009 Jan;276(2):479-96.PMID: 19120451 [PubMed - indexed for MEDLINE]Related articles

Increased expression of lipocalin-type prostaglandin D2 synthase in osteoarthritic cartilage.

Zayed N, Li X, Chabane N, Benderdour M, Martel-Pelletier J, Pelletier JP, Duval N, Fahmi H.

Arthritis Res Ther. 2008;10(6):R146. Epub 2008 Dec 18.PMID: 19094210 [PubMed - indexed for MEDLINE]Related articlesFree article

Clarification to article entitled "global nurse migration today".

Pelletier J.

J Nurs Scholarsh. 2008;40(4):300; author reply 300. No abstract available. PMID: 19094141 [PubMed - indexed for MEDLINE]Related articles