PubMed

RSV replication is attenuated by counteracting expression of the suppressor of cytokine signaling (SOCS) molecules.

Hashimoto K, Ishibashi K, Ishioka K, Zhao D, Sato M, Ohara S, Abe Y, Kawasaki Y, Sato Y, Yokota S, Fujii N, Peebles RS Jr, Hosoya M, Suzutani T.

Virology. 2009 Sep 1;391(2):162-70. Epub 2009 Jul 12.PMID: 19595407 [PubMed - indexed for MEDLINE]Related articles

STAT1 negatively regulates lung basophil IL-4 expression induced by respiratory syncytial virus infection.

Moore ML, Newcomb DC, Parekh VV, Van Kaer L, Collins RD, Zhou W, Goleniewska K, Chi MH, Mitchell D, Boyce JA, Durbin JE, Sturkie C, Peebles RS Jr.

J Immunol. 2009 Aug 1;183(3):2016-26. Epub 2009 Jul 8.PMID: 19587017 [PubMed - indexed for MEDLINE]Related articles

Dietary supplementation of omega-3 fatty acid-containing fish oil suppresses F2-isoprostanes but enhances inflammatory cytokine response in a mouse model of ovalbumin-induced allergic lung inflammation.

Yin H, Liu W, Goleniewska K, Porter NA, Morrow JD, Peebles RS Jr.

Free Radic Biol Med. 2009 Sep 1;47(5):622-8. Epub 2009 Jun 6.PMID: 19501157 [PubMed - in process]Related articles

Bugs and asthma: a different disease?

Newcomb DC, Peebles RS Jr.

Proc Am Thorac Soc. 2009 May 1;6(3):266-71. Review.PMID: 19387028 [PubMed - indexed for MEDLINE]Related articlesFree article

A functional IL-13 receptor is expressed on polarized murine CD4+ Th17 cells and IL-13 signaling attenuates Th17 cytokine production.

Newcomb DC, Zhou W, Moore ML, Goleniewska K, Hershey GK, Kolls JK, Peebles RS Jr.

J Immunol. 2009 May 1;182(9):5317-21.PMID: 19380778 [PubMed - indexed for MEDLINE]Related articles

A chimeric A2 strain of respiratory syncytial virus (RSV) with the fusion protein of RSV strain line 19 exhibits enhanced viral load, mucus, and airway dysfunction.

Moore ML, Chi MH, Luongo C, Lukacs NW, Polosukhin VV, Huckabee MM, Newcomb DC, Buchholz UJ, Crowe JE Jr, Goleniewska K, Williams JV, Collins PL, Peebles RS Jr.

J Virol. 2009 May;83(9):4185-94. Epub 2009 Feb 11.PMID: 19211758 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel concepts in virally induced asthma.

Huckabee MM, Peebles RS Jr.

Clin Mol Allergy. 2009 Jan 20;7:2.PMID: 19154602 [PubMed - in process]Related articlesFree article

DSCG reduces RSV-induced illness in RSV-infected mice.

Hashimoto K, Mori S, Hashimoto Y, Kaneko H, Ishibashi K, Ishioka K, Kawasaki Y, Peebles RS Jr, Munakata M, Hosoya M, Suzutani T.

J Med Virol. 2009 Feb;81(2):354-61.PMID: 19107959 [PubMed - indexed for MEDLINE]Related articles

Cyclooxygenase inhibition during allergic sensitization increases STAT6-independent primary and memory Th2 responses.

Zhou W, Newcomb DC, Moore ML, Goleniewska K, O'Neal JF, Peebles RS Jr.

J Immunol. 2008 Oct 15;181(8):5360-7.PMID: 18832692 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional polymorphism of the promoter region of the prostacyclin synthase gene and severity of RSV infection in hospitalized children.

Hashimoto K, Ishibashi K, Gebretsadik T, Hartert TV, Yamamoto A, Nakayama T, Ohashi K, Sakata H, Kawasaki Y, Katayose M, Sakuma H, Suzuki H, Hosoya M, Peebles RS Jr, Suzutani T.

J Med Virol. 2008 Nov;80(11):2015-22.PMID: 18814254 [PubMed - indexed for MEDLINE]Related articles

Differential regulation of GM1 and asialo-GM1 expression by T cells and natural killer (NK) cells in respiratory syncytial virus infection.

Moore ML, Chi MH, Goleniewska K, Durbin JE, Peebles RS Jr.

Viral Immunol. 2008 Sep;21(3):327-39.PMID: 18788941 [PubMed - indexed for MEDLINE]Related articles

The spectrum and treatment of angioedema.

Temiño VM, Peebles RS Jr.

Am J Med. 2008 Apr;121(4):282-6. Review.PMID: 18374684 [PubMed - indexed for MEDLINE]Related articles

Type I interferon regulates respiratory virus infected dendritic cell maturation and cytokine production.

Rudd BD, Luker GD, Luker KE, Peebles RS, Lukacs NW.

Viral Immunol. 2007 Dec;20(4):531-40.PMID: 18158727 [PubMed - indexed for MEDLINE]Related articles

A mechanistic advance in understanding RSV pathogenesis, but still a long way from therapy.

Peebles RS Jr, Moore ML.

Am J Respir Cell Mol Biol. 2007 Oct;37(4):375-7. No abstract available. PMID: 17872592 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction and function of lipocalin prostaglandin D synthase in host immunity.

Joo M, Kwon M, Sadikot RT, Kingsley PJ, Marnett LJ, Blackwell TS, Peebles RS Jr, Urade Y, Christman JW.

J Immunol. 2007 Aug 15;179(4):2565-75.PMID: 17675519 [PubMed - indexed for MEDLINE]Related articlesFree article

Conditional regulation of cyclooxygenase-2 in tracheobronchial epithelial cells modulates pulmonary immunity.

Park GY, Hu N, Wang X, Sadikot RT, Yull FE, Joo M, Peebles RS Jr, Blackwell TS, Christman JW.

Clin Exp Immunol. 2007 Nov;150(2):245-54. Epub 2007 Aug 2.PMID: 17672868 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential type I interferon induction by respiratory syncytial virus and influenza a virus in vivo.

Jewell NA, Vaghefi N, Mertz SE, Akter P, Peebles RS Jr, Bakaletz LO, Durbin RK, Flaño E, Durbin JE.

J Virol. 2007 Sep;81(18):9790-800. Epub 2007 Jul 11.PMID: 17626092 [PubMed - indexed for MEDLINE]Related articlesFree article

Bacterial clearance of Pseudomonas aeruginosa is enhanced by the inhibition of COX-2.

Sadikot RT, Zeng H, Azim AC, Joo M, Dey SK, Breyer RM, Peebles RS, Blackwell TS, Christman JW.

Eur J Immunol. 2007 Apr;37(4):1001-9.PMID: 17330822 [PubMed - indexed for MEDLINE]Related articles

Cutting Edge: Oseltamivir decreases T cell GM1 expression and inhibits clearance of respiratory syncytial virus: potential role of endogenous sialidase in antiviral immunity.

Moore ML, Chi MH, Zhou W, Goleniewska K, O'Neal JF, Higginbotham JN, Peebles RS Jr.

J Immunol. 2007 Mar 1;178(5):2651-4.PMID: 17312105 [PubMed - indexed for MEDLINE]Related articlesFree article

Synthetic prostacyclin analogs differentially regulate macrophage function via distinct analog-receptor binding specificities.

Aronoff DM, Peres CM, Serezani CH, Ballinger MN, Carstens JK, Coleman N, Moore BB, Peebles RS, Faccioli LH, Peters-Golden M.

J Immunol. 2007 Feb 1;178(3):1628-34.PMID: 17237412 [PubMed - indexed for MEDLINE]Related articlesFree article

Prostaglandin I2 analogs inhibit proinflammatory cytokine production and T cell stimulatory function of dendritic cells.

Zhou W, Hashimoto K, Goleniewska K, O'Neal JF, Ji S, Blackwell TS, Fitzgerald GA, Egan KM, Geraci MW, Peebles RS Jr.

J Immunol. 2007 Jan 15;178(2):702-10.PMID: 17202330 [PubMed - indexed for MEDLINE]Related articlesFree article

Prostaglandin I2 analogs inhibit Th1 and Th2 effector cytokine production by CD4 T cells.

Zhou W, Blackwell TS, Goleniewska K, O'Neal JF, Fitzgerald GA, Lucitt M, Breyer RM, Peebles RS Jr.

J Leukoc Biol. 2007 Mar;81(3):809-17. Epub 2006 Nov 29.PMID: 17135575 [PubMed - indexed for MEDLINE]Related articlesFree article

IL-13 is associated with reduced illness and replication in primary respiratory syncytial virus infection in the mouse.

Zhou W, Hashimoto K, Moore ML, Elias JA, Zhu Z, Durbin J, Colasurdo G, Rutigliano JA, Chiappetta CL, Goleniewska K, O'Neal JF, Graham BS, Peebles RS Jr.

Microbes Infect. 2006 Nov-Dec;8(14-15):2880-9. Epub 2006 Oct 24.PMID: 17110149 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential immune responses and pulmonary pathophysiology are induced by two different strains of respiratory syncytial virus.

Lukacs NW, Moore ML, Rudd BD, Berlin AA, Collins RD, Olson SJ, Ho SB, Peebles RS Jr.

Am J Pathol. 2006 Sep;169(3):977-86.PMID: 16936271 [PubMed - indexed for MEDLINE]Related articlesFree article

Respiratory syncytial virus disease mechanisms implicated by human, animal model, and in vitro data facilitate vaccine strategies and new therapeutics.

Moore ML, Peebles RS Jr.

Pharmacol Ther. 2006 Nov;112(2):405-24. Epub 2006 Jul 3. Review.PMID: 16820210 [PubMed - indexed for MEDLINE]Related articles

Respiratory syncytial virus infection reduces beta2-adrenergic responses in human airway smooth muscle.

Moore PE, Cunningham G, Calder MM, DeMatteo AD Jr, Peeples ME, Summar ML, Peebles RS Jr.

Am J Respir Cell Mol Biol. 2006 Nov;35(5):559-64. Epub 2006 Jun 8.PMID: 16763224 [PubMed - indexed for MEDLINE]Related articlesFree article

Update on the role of prostaglandins in allergic lung inflammation: separating friends from foes, harder than you might think.

Moore ML, Peebles RS Jr.

J Allergy Clin Immunol. 2006 May;117(5):1036-9. Epub 2006 Feb 15. Review.PMID: 16675329 [PubMed - indexed for MEDLINE]Related articles

The relationship of rhinovirus-associated asthma hospitalizations with inhaled corticosteroids and smoking.

Venarske DL, Busse WW, Griffin MR, Gebretsadik T, Shintani AK, Minton PA, Peebles RS, Hamilton R, Weisshaar E, Vrtis R, Higgins SB, Hartert TV.

J Infect Dis. 2006 Jun 1;193(11):1536-43. Epub 2006 Apr 27.PMID: 16652282 [PubMed - indexed for MEDLINE]Related articles

Oxidant stress modulates murine allergic airway responses.

Talati M, Meyrick B, Peebles RS Jr, Davies SS, Dworski R, Mernaugh R, Mitchell D, Boothby M, Roberts LJ 2nd, Sheller JR.

Free Radic Biol Med. 2006 Apr 1;40(7):1210-9. Epub 2005 Dec 9.PMID: 16545689 [PubMed - indexed for MEDLINE]Related articles

Allergen-induced airway hyperresponsiveness mediated by cyclooxygenase inhibition is not dependent on 5-lipoxygenase or IL-5, but is IL-13 dependent.

Peebles RS Jr, Hashimoto K, Sheller JR, Moore ML, Morrow JD, Ji S, Elias JA, Goleniewska K, O'neal J, Mitchell DB, Graham BS, Zhou W.

J Immunol. 2005 Dec 15;175(12):8253-9.PMID: 16339565 [PubMed - indexed for MEDLINE]Related articlesFree article

Pneumothorax-associated pleural eosinophilia in mice is interleukin-5 but not interleukin-13 dependent.

Kalomenidis I, Guo Y, Peebles RS, Lane KB, Papiris S, Elias J, Light RW.

Chest. 2005 Oct;128(4):2978-83.PMID: 16236975 [PubMed - indexed for MEDLINE]Related articlesFree article

Respiratory syncytial virus infection in the absence of STAT 1 results in airway dysfunction, airway mucus, and augmented IL-17 levels.

Hashimoto K, Durbin JE, Zhou W, Collins RD, Ho SB, Kolls JK, Dubin PJ, Sheller JR, Goleniewska K, O'Neal JF, Olson SJ, Mitchell D, Graham BS, Peebles RS Jr.

J Allergy Clin Immunol. 2005 Sep;116(3):550-7.PMID: 16159623 [PubMed - indexed for MEDLINE]Related articles

Human metapneumovirus infection plays an etiologic role in acute asthma exacerbations requiring hospitalization in adults.

Williams JV, Crowe JE Jr, Enriquez R, Minton P, Peebles RS Jr, Hamilton RG, Higgins S, Griffin M, Hartert TV.

J Infect Dis. 2005 Oct 1;192(7):1149-53. Epub 2005 Aug 29.PMID: 16136455 [PubMed - indexed for MEDLINE]Related articlesFree article

Pathogenesis of respiratory syncytial virus infection in the murine model.

Peebles RS Jr, Graham BS.

Proc Am Thorac Soc. 2005;2(2):110-5. Review.PMID: 16113477 [PubMed - indexed for MEDLINE]Related articlesFree article

Anaphylactic shock: pathophysiology, recognition, and treatment.

Johnson RF, Peebles RS.

Semin Respir Crit Care Med. 2004 Dec;25(6):695-703.PMID: 16088511 [PubMed]Related articles

Eotaxin-3 and interleukin-5 pleural fluid levels are associated with pleural fluid eosinophilia in post-coronary artery bypass grafting pleural effusions.

Kalomenidis I, Stathopoulos GT, Barnette R, Guo Y, Peebles RS, Blackwell TS, Light RW.

Chest. 2005 Jun;127(6):2094-100.PMID: 15947325 [PubMed - indexed for MEDLINE]Related articlesFree article

Cyclooxygenase inhibition augments allergic inflammation through CD4-dependent, STAT6-independent mechanisms.

Hashimoto K, Sheller JR, Morrow JD, Collins RD, Goleniewska K, O'Neal J, Zhou W, Ji S, Mitchell DB, Graham BS, Peebles RS Jr.

J Immunol. 2005 Jan 1;174(1):525-32.PMID: 15611279 [PubMed - indexed for MEDLINE]Related articlesFree article

Signaling through the prostaglandin I2 receptor IP protects against respiratory syncytial virus-induced illness.

Hashimoto K, Graham BS, Geraci MW, FitzGerald GA, Egan K, Zhou W, Goleniewska K, O'Neal JF, Morrow JD, Durbin RK, Wright PF, Collins RD, Suzutani T, Peebles RS Jr.

J Virol. 2004 Oct;78(19):10303-9.PMID: 15367596 [PubMed - indexed for MEDLINE]Related articlesFree article

Respiratory syncytial virus in allergic lung inflammation increases Muc5ac and gob-5.

Hashimoto K, Graham BS, Ho SB, Adler KB, Collins RD, Olson SJ, Zhou W, Suzutani T, Jones PW, Goleniewska K, O'Neal JF, Peebles RS Jr.

Am J Respir Crit Care Med. 2004 Aug 1;170(3):306-12. Epub 2004 May 6.PMID: 15130904 [PubMed - indexed for MEDLINE]Related articlesFree article

Viral infections, atopy, and asthma: is there a causal relationship?

Peebles RS Jr.

J Allergy Clin Immunol. 2004 Jan;113(1 Suppl):S15-8. Review.PMID: 14694345 [PubMed - indexed for MEDLINE]Related articles

Pleural fluid levels of vascular cell adhesion molecule-1 are elevated in eosinophilic pleural effusions.

Kalomenidis I, Mohamed KH, Lane KB, Peebles RS, Barnette R, Rodriguez RM, Light RW.

Chest. 2003 Jul;124(1):159-66.PMID: 12853519 [PubMed - indexed for MEDLINE]Related articlesFree article

The complex relationship between respiratory syncytial virus and allergy in lung disease.

Peebles RS Jr, Hashimoto K, Graham BS.

Viral Immunol. 2003;16(1):25-34. Review.PMID: 12725686 [PubMed - indexed for MEDLINE]Related articles

Selective I kappa B kinase expression in airway epithelium generates neutrophilic lung inflammation.

Sadikot RT, Han W, Everhart MB, Zoia O, Peebles RS, Jansen ED, Yull FE, Christman JW, Blackwell TS.

J Immunol. 2003 Jan 15;170(2):1091-8.PMID: 12517978 [PubMed - indexed for MEDLINE]Related articlesFree article

Highlights from the annual scientific assembly: patient-centered approaches to asthma management: strategies for treatment and management of asthma.

Peebles RS, Hartert TV.

South Med J. 2002 Jul;95(7):775-9. Review.PMID: 12144090 [PubMed - indexed for MEDLINE]Related articles

Expression of activation markers on alveolar macrophages in allergic asthmatics after endobronchial or whole-lung allergen challenge.

Viksman MY, Bochner BS, Peebles RS, Schleimer RP, Liu MC.

Clin Immunol. 2002 Jul;104(1):77-85.PMID: 12139951 [PubMed - indexed for MEDLINE]Related articles

Anaphylaxis and anaphylactoid reactions. A guide to prevention, recognition, and emergent treatment.

Rusznak C, Peebles RS Jr.

Postgrad Med. 2002 May;111(5):101-4, 107-8, 111-4. Review.PMID: 12040857 [PubMed - indexed for MEDLINE]Related articles

Suppression of airway hyperresponsiveness induced by ovalbumin sensitisation and RSV infection with Y-27632, a Rho kinase inhibitor.

Hashimoto K, Peebles RS Jr, Sheller JR, Jarzecka K, Furlong J, Mitchell DB, Hartert TV, Graham BS.

Thorax. 2002 Jun;57(6):524-7.PMID: 12037228 [PubMed - indexed for MEDLINE]Related articlesFree article

Dietary antioxidants and adult asthma.

Hartert TV, Peebles RS.

Curr Opin Allergy Clin Immunol. 2001 Oct;1(5):421-9. Review.PMID: 11964722 [PubMed - indexed for MEDLINE]Related articles

Selective cyclooxygenase-1 and -2 inhibitors each increase allergic inflammation and airway hyperresponsiveness in mice.

Peebles RS Jr, Hashimoto K, Morrow JD, Dworski R, Collins RD, Hashimoto Y, Christman JW, Kang KH, Jarzecka K, Furlong J, Mitchell DB, Talati M, Graham BS, Sheller JR.

Am J Respir Crit Care Med. 2002 Apr 15;165(8):1154-60.PMID: 11956061 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of IFN in respiratory syncytial virus pathogenesis.

Durbin JE, Johnson TR, Durbin RK, Mertz SE, Morotti RA, Peebles RS, Graham BS.

J Immunol. 2002 Mar 15;168(6):2944-52.PMID: 11884466 [PubMed - indexed for MEDLINE]Related articlesFree article