PubMed

Combining insulin with metformin or an insulin secretagogue in non-obese patients with type 2 diabetes: 12 month, randomised, double blind trial.

Lund SS, Tarnow L, Frandsen M, Nielsen BB, Hansen BV, Pedersen O, Parving HH, Vaag AA.

BMJ. 2009 Nov 9;339:b4324. doi: 10.1136/bmj.b4324.PMID: 19900993 [PubMed - in process]Related articlesFree article

Obesity-related Polymorphisms and Their Associations With the Ability to Regulate Fat Oxidation in Obese Europeans: The NUGENOB Study.

Corpeleijn E, Petersen L, Holst C, Saris WH, Astrup A, Langin D, Macdonald I, Martinez JA, Oppert JM, Polak J, Pedersen O, Froguel P, Arner P, Sørensen TI, Blaak EE.

Obesity (Silver Spring). 2009 Oct 29. [Epub ahead of print]PMID: 19876004 [PubMed - as supplied by publisher]Related articles

[We have taken the challenge]

Aslaksen A, Pedersen OB, Carlsen B, Hartveit M.

Tidsskr Nor Laegeforen. 2009 Oct 22;129(20):2136. Norwegian. No abstract available. PMID: 19855458 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic association analysis of LARS2 with type 2 diabetes.

Reiling E, Jafar-Mohammadi B, van 't Riet E, Weedon MN, van Vliet-Ostaptchouk JV, Hansen T, Saxena R, van Haeften TW, Arp PA, Das S, Nijpels G, Groenewoud MJ, van Hove EC, Uitterlinden AG, Smit JW, Morris AD, Doney AS, Palmer CN, Guiducci C, Hattersley AT, Frayling TM, Pedersen O, Slagboom PE, Altshuler DM, Groop L, Romijn JA, Maassen JA, Hofker MH, Dekker JM, McCarthy MI, 't Hart LM.

Diabetologia. 2009 Oct 22. [Epub ahead of print]PMID: 19847392 [PubMed - as supplied by publisher]Related articles

Common variants near MC4R in relation to body fat, body fat distribution, metabolic traits and energy expenditure.

Kring SI, Holst C, Toubro S, Astrup A, Hansen T, Pedersen O, Sørensen TI.

Int J Obes (Lond). 2009 Oct 20. [Epub ahead of print]PMID: 19844209 [PubMed - as supplied by publisher]Related articles

Past and Current Body Size Affect Validity of Reported Energy Intake among Middle-Aged Danish Men.

Nielsen BM, Nielsen MM, Toubro S, Pedersen O, Astrup A, Sørensen TI, Jess T, Heitmann BL.

J Nutr. 2009 Oct 14. [Epub ahead of print]PMID: 19828683 [PubMed - as supplied by publisher]Related articles

Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study.

Boesgaard TW, Gjesing AP, Grarup N, Rutanen J, Jansson PA, Hribal ML, Sesti G, Fritsche A, Stefan N, Staiger H, Häring H, Smith U, Laakso M, Pedersen O, Hansen T; EUGENE2 Consortium.

PLoS One. 2009 Sep 30;4(9):e7236.PMID: 19789630 [PubMed - in process]Related articlesFree article

No consistent effect of ADRB2 haplotypes on obesity, hypertension and quantitative traits of body fatness and blood pressure among 6,514 adult danes.

Gjesing AP, Sparsø T, Borch-Johnsen K, Jørgensen T, Pedersen O, Hansen T, Olsen NV.

PLoS One. 2009 Sep 25;4(9):e7206.PMID: 19779622 [PubMed - in process]Related articlesFree article

Mutations in the VNTR of the carboxyl-ester lipase gene (CEL) are a rare cause of monogenic diabetes.

Torsvik J, Johansson S, Johansen A, Ek J, Minton J, Ræder H, Ellard S, Hattersley A, Pedersen O, Hansen T, Molven A, Njølstad PR.

Hum Genet. 2009 Sep 17. [Epub ahead of print]PMID: 19760265 [PubMed - as supplied by publisher]Related articles

New concepts for expressing FEV1 arising from survival analysis.

Miller MR, Pedersen OF.

Eur Respir J. 2009 Sep 9. [Epub ahead of print]PMID: 19741033 [PubMed - as supplied by publisher]Related articles

Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia.

Rung J, Cauchi S, Albrechtsen A, Shen L, Rocheleau G, Cavalcanti-Proença C, Bacot F, Balkau B, Belisle A, Borch-Johnsen K, Charpentier G, Dina C, Durand E, Elliott P, Hadjadj S, Järvelin MR, Laitinen J, Lauritzen T, Marre M, Mazur A, Meyre D, Montpetit A, Pisinger C, Posner B, Poulsen P, Pouta A, Prentki M, Ribel-Madsen R, Ruokonen A, Sandbaek A, Serre D, Tichet J, Vaxillaire M, Wojtaszewski JF, Vaag A, Hansen T, Polychronakos C, Pedersen O, Froguel P, Sladek R.

Nat Genet. 2009 Oct;41(10):1110-5. Epub 2009 Sep 6. Erratum in: Nat Genet. 2009 Oct;41(10):1156. PMID: 19734900 [PubMed - indexed for MEDLINE]Related articles

Debating the definition of airflow obstruction: time to move on?

Miller MR, Pedersen OF, Pellegrino R, Brusasco V.

Eur Respir J. 2009 Sep;34(3):527-8. No abstract available. PMID: 19720804 [PubMed - in process]Related articles

Polymorphisms of serotonin receptor 2A and 2C genes and COMT in relation to obesity and type 2 diabetes.

Kring SI, Werge T, Holst C, Toubro S, Astrup A, Hansen T, Pedersen O, Sørensen TI.

PLoS One. 2009 Aug 19;4(8):e6696.PMID: 19690620 [PubMed - in process]Related articlesFree article

Macronutrient-specific effect of FTO rs9939609 in response to a 10-week randomized hypo-energetic diet among obese Europeans.

Grau K, Hansen T, Holst C, Astrup A, Saris WH, Arner P, Rössner S, Macdonald I, Polak J, Oppert JM, Langin D, Martinez JA, Pedersen O, Sørensen TI.

Int J Obes (Lond). 2009 Nov;33(11):1227-34. Epub 2009 Aug 18.PMID: 19687793 [PubMed - in process]Related articles

A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads.

Rose CS, Grarup N, Krarup NT, Poulsen P, Wegner L, Nielsen T, Banasik K, Faerch K, Andersen G, Albrechtsen A, Borch-Johnsen K, Clausen JO, Jørgensen T, Vaag A, Pedersen O, Hansen T.

Diabetologia. 2009 Oct;52(10):2122-9. Epub 2009 Aug 8.PMID: 19669124 [PubMed - in process]Related articles

Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics.

Koutnikova H, Laakso M, Lu L, Combe R, Paananen J, Kuulasmaa T, Kuusisto J, Häring HU, Hansen T, Pedersen O, Smith U, Hanefeld M, Williams RW, Auwerx J.

PLoS Genet. 2009 Aug;5(8):e1000591. Epub 2009 Aug 7.PMID: 19662162 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variant in HK1 is associated with a proanemic state and A1C but not other glycemic control-related traits.

Bonnefond A, Vaxillaire M, Labrune Y, Lecoeur C, Chèvre JC, Bouatia-Naji N, Cauchi S, Balkau B, Marre M, Tichet J, Riveline JP, Hadjadj S, Gallois Y, Czernichow S, Hercberg S, Kaakinen M, Wiesner S, Charpentier G, Lévy-Marchal C, Elliott P, Jarvelin MR, Horber F, Dina C, Pedersen O, Sladek R, Meyre D, Froguel P.

Diabetes. 2009 Nov;58(11):2687-97. Epub 2009 Aug 3.PMID: 19651813 [PubMed - in process]Related articles

Huntington's disease does not appear to increase the risk of diabetes mellitus.

Boesgaard TW, Nielsen TT, Josefsen K, Hansen T, Jørgensen T, Pedersen O, Nørremølle A, Nielsen JE, Hasholt L.

J Neuroendocrinol. 2009 Sep;21(9):770-6. Epub 2009 Jul 7.PMID: 19602103 [PubMed - in process]Related articles

Regulation and function of FTO mRNA expression in human skeletal muscle and subcutaneous adipose tissue.

Grunnet LG, Nilsson E, Ling C, Hansen T, Pedersen O, Groop L, Vaag A, Poulsen P.

Diabetes. 2009 Oct;58(10):2402-8. Epub 2009 Jul 8.PMID: 19587359 [PubMed - indexed for MEDLINE]Related articles

Association of polymorphisms of the CHI3L1 gene with asthma and atopy: a populations-based study of 6514 Danish adults.

Rathcke CN, Holmkvist J, Husmoen LL, Hansen T, Pedersen O, Vestergaard H, Linneberg A.

PLoS One. 2009 Jul 1;4(7):e6106.PMID: 19568425 [PubMed - indexed for MEDLINE]Related articlesFree article

Development of a type 2 diabetes risk model from a panel of serum biomarkers from the Inter99 cohort.

Kolberg JA, Jørgensen T, Gerwien RW, Hamren S, McKenna MP, Moler E, Rowe MW, Urdea MS, Xu XM, Hansen T, Pedersen O, Borch-Johnsen K.

Diabetes Care. 2009 Jul;32(7):1207-12.PMID: 19564473 [PubMed - indexed for MEDLINE]Related articlesFree article

[Pharmacological hypertension therapy]

Pedersen OL, Christensen KL, Bang LE, Ibsen H, Schultz-Larsen P.

Ugeskr Laeger. 2009 Jun 8;171(24):2022-5. Danish. PMID: 19523367 [PubMed - indexed for MEDLINE]Related articles

The type 2 diabetes associated minor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load.

Holmkvist J, Banasik K, Andersen G, Unoki H, Jensen TS, Pisinger C, Borch-Johnsen K, Sandbaek A, Lauritzen T, Brunak S, Maeda S, Hansen T, Pedersen O.

PLoS One. 2009 Jun 11;4(6):e5872.PMID: 19516902 [PubMed - indexed for MEDLINE]Related articlesFree article

[Diabetes in infants may be treated with sulfonylurea as a replacement for insulin]

Lauridsen MH, Boesgaard TW, Pedersen OB, Hansen T, Hertz B.

Ugeskr Laeger. 2009 Jun 1;171(23):1923-4. Danish. PMID: 19500515 [PubMed - indexed for MEDLINE]Related articles

Variation in CHI3LI in relation to type 2 diabetes and related quantitative traits.

Rathcke CN, Holmkvist J, Jørgensen T, Borch-Johnsen K, Hansen T, Pedersen OB, Vestergaard H.

PLoS One. 2009;4(5):e5469. Epub 2009 May 7.PMID: 19421404 [PubMed - indexed for MEDLINE]Related articlesFree article

Overweight and the metabolic syndrome in adult offspring of women with diet-treated gestational diabetes mellitus or type 1 diabetes.

Clausen TD, Mathiesen ER, Hansen T, Pedersen O, Jensen DM, Lauenborg J, Schmidt L, Damm P.

J Clin Endocrinol Metab. 2009 Jul;94(7):2464-70. Epub 2009 May 5.PMID: 19417040 [PubMed - indexed for MEDLINE]Related articles

Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction.

Sparsø T, Grarup N, Andreasen C, Albrechtsen A, Holmkvist J, Andersen G, Jørgensen T, Borch-Johnsen K, Sandbaek A, Lauritzen T, Madsbad S, Hansen T, Pedersen O.

Diabetologia. 2009 Jul;52(7):1308-14. Epub 2009 Apr 29.PMID: 19404609 [PubMed - indexed for MEDLINE]Related articles

Several obesity- and nutrient-related gene polymorphisms but not FTO and UCP variants modulate postabsorptive resting energy expenditure and fat-induced thermogenesis in obese individuals: the NUGENOB study.

Goossens GH, Petersen L, Blaak EE, Hul G, Arner P, Astrup A, Froguel P, Patel K, Pedersen O, Polak J, Oppert JM, Martinez JA, Sørensen TI, Saris WH; NUGENOB Consortium.

Int J Obes (Lond). 2009 Jun;33(6):669-79. Epub 2009 Apr 28.PMID: 19399022 [PubMed - in process]Related articles

Predictors of future fasting and 2-h post-OGTT plasma glucose levels in middle-aged men and women-the Inter99 study.

Faerch K, Vaag A, Witte DR, Jørgensen T, Pedersen O, Borch-Johnsen K.

Diabet Med. 2009 Apr;26(4):377-83.PMID: 19388967 [PubMed - indexed for MEDLINE]Related articles

Identification of novel variants in the hepatocyte nuclear factor-1alpha gene in South Indian patients with maturity onset diabetes of young.

Radha V, Ek J, Anuradha S, Hansen T, Pedersen O, Mohan V.

J Clin Endocrinol Metab. 2009 Jun;94(6):1959-65. Epub 2009 Mar 31.PMID: 19336507 [PubMed - indexed for MEDLINE]Related articles

G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans.

Sparsø T, Bonnefond A, Andersson E, Bouatia-Naji N, Holmkvist J, Wegner L, Grarup N, Gjesing AP, Banasik K, Cavalcanti-Proença C, Marchand M, Vaxillaire M, Charpentier G, Jarvelin MR, Tichet J, Balkau B, Marre M, Lévy-Marchal C, Faerch K, Borch-Johnsen K, Jørgensen T, Madsbad S, Poulsen P, Vaag A, Dina C, Hansen T, Pedersen O, Froguel P.

Diabetes. 2009 Jun;58(6):1450-6. Epub 2009 Mar 26.PMID: 19324940 [PubMed - indexed for MEDLINE]Related articlesFree article

Ultrasound in evaluation of post-interventional femoral vein obstruction: a case report.

Lønnebakken MT, Gerdts E, Wirsching J, Pedersen OM.

Cardiovasc Ultrasound. 2009 Mar 26;7:14.PMID: 19323809 [PubMed - indexed for MEDLINE]Related articlesFree article

On the recurrence risk of arthritis among psoriatic patients.

Pedersen OB, Junker P.

Scand J Rheumatol. 2009 Mar 23:1-2. [Epub ahead of print] No abstract available. PMID: 19308804 [PubMed - as supplied by publisher]Related articles

The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men.

Pilgaard K, Jensen CB, Schou JH, Lyssenko V, Wegner L, Brøns C, Vilsbøll T, Hansen T, Madsbad S, Holst JJ, Vølund A, Poulsen P, Groop L, Pedersen O, Vaag AA.

Diabetologia. 2009 Jul;52(7):1298-307. Epub 2009 Mar 14.PMID: 19288077 [PubMed - indexed for MEDLINE]Related articles

Study rationale and design of the CIMT trial: the Copenhagen Insulin and Metformin Therapy trial.

Lundby Christensen L, Almdal T, Boesgaard T, Breum L, Dunn E, Gade-Rasmussen B, Gluud C, Hedetoft C, Jarloev A, Jensen T, Krarup T, Johansen LB, Lund SS, Madsbad S, Mathiesen E, Moelvig J, Nielsen F, Perrild H, Pedersen O, Roeder M, Sneppen SB, Snorgaard O, Tarnow L, Thorsteinsson B, Vaag A, Vestergaard H, Wetterslev J, Wiinberg N; CIMT Trial Group.

Diabetes Obes Metab. 2009 Apr;11(4):315-22.PMID: 19267709 [PubMed - in process]Related articles

Studies of CTNNBL1 and FDFT1 variants and measures of obesity: analyses of quantitative traits and case-control studies in 18,014 Danes.

Andreasen CH, Mogensen MS, Borch-Johnsen K, Sandbaek A, Lauritzen T, Almind K, Hansen L, Jørgensen T, Pedersen O, Hansen T.

BMC Med Genet. 2009 Feb 26;10:17.PMID: 19245693 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional SOCS1 polymorphisms are associated with variation in obesity in whites.

Gylvin T, Ek J, Nolsøe R, Albrechtsen A, Andersen G, Bergholdt R, Brorsson C, Bang-Berthelsen CH, Hansen T, Karlsen AE, Billestrup N, Borch-Johnsen K, Jørgensen T, Pedersen O, Mandrup-Poulsen T, Nerup J, Pociot F.

Diabetes Obes Metab. 2009 Mar;11(3):196-203.PMID: 19215277 [PubMed - indexed for MEDLINE]Related articles

Fatness-associated FTO gene variant increases mortality independent of fatness--in cohorts of Danish men.

Zimmermann E, Kring SI, Berentzen TL, Holst C, Pers TH, Hansen T, Pedersen O, Sørensen TI, Jess T.

PLoS One. 2009;4(2):e4428. Epub 2009 Feb 13.PMID: 19214238 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study.

Reiling E, van Vliet-Ostaptchouk JV, van 't Riet E, van Haeften TW, Arp PA, Hansen T, Kremer D, Groenewoud MJ, van Hove EC, Romijn JA, Smit JW, Nijpels G, Heine RJ, Uitterlinden AG, Pedersen O, Slagboom PE, Maassen JA, Hofker MH, 't Hart LM, Dekker JM.

Eur J Hum Genet. 2009 Aug;17(8):1056-62. Epub 2009 Feb 11.PMID: 19209188 [PubMed - indexed for MEDLINE]Related articles

[Bleeding peptic ulcer. Prevalence of Helicobacter pylori and use of nonsteroidal anti-inflammatory drugs/acetylsalicylic acid]

Vestergård A, Bredahl K, de Muckadell OB, Pedersen OB, Hansen JM.

Ugeskr Laeger. 2009 Jan 19;171(4):235-9. Danish. PMID: 19174039 [PubMed - indexed for MEDLINE]Related articles

Dietary patterns predict changes in two-hour post-oral glucose tolerance test plasma glucose concentrations in middle-aged adults.

Lau C, Toft U, Tetens I, Carstensen B, Jørgensen T, Pedersen O, Borch-Johnsen K.

J Nutr. 2009 Mar;139(3):588-93. Epub 2009 Jan 21.PMID: 19158222 [PubMed - indexed for MEDLINE]Related articles

Progression to impaired glucose regulation and diabetes in the population-based Inter99 study.

Engberg S, Vistisen D, Lau C, Glümer C, Jørgensen T, Pedersen O, Borch-Johnsen K.

Diabetes Care. 2009 Apr;32(4):606-11. Epub 2008 Dec 29. Erratum in: Diabetes Care. 2009 Sep;32(9):1751. PMID: 19114617 [PubMed - indexed for MEDLINE]Related articlesFree article

Lack of association between PKLR rs3020781 and NOS1AP rs7538490 and type 2 diabetes, overweight, obesity and related metabolic phenotypes in a Danish large-scale study: case-control studies and analyses of quantitative traits.

Andreasen CH, Mogensen MS, Borch-Johnsen K, Sandbaek A, Lauritzen T, Almind K, Hansen L, Jørgensen T, Pedersen O, Hansen T.

BMC Med Genet. 2008 Dec 26;9:118.PMID: 19111066 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity.

Thorleifsson G, Walters GB, Gudbjartsson DF, Steinthorsdottir V, Sulem P, Helgadottir A, Styrkarsdottir U, Gretarsdottir S, Thorlacius S, Jonsdottir I, Jonsdottir T, Olafsdottir EJ, Olafsdottir GH, Jonsson T, Jonsson F, Borch-Johnsen K, Hansen T, Andersen G, Jorgensen T, Lauritzen T, Aben KK, Verbeek AL, Roeleveld N, Kampman E, Yanek LR, Becker LC, Tryggvadottir L, Rafnar T, Becker DM, Gulcher J, Kiemeney LA, Pedersen O, Kong A, Thorsteinsdottir U, Stefansson K.

Nat Genet. 2009 Jan;41(1):18-24. Epub 2008 Dec 14.PMID: 19079260 [PubMed - indexed for MEDLINE]Related articles

Surviving floods: leaf gas films improve O(2) and CO(2) exchange, root aeration, and growth of completely submerged rice.

Pedersen O, Rich SM, Colmer TD.

Plant J. 2009 Jan 17. [Epub ahead of print]PMID: 19077169 [PubMed - as supplied by publisher]Related articles

Variants near MC4R are associated with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14,940 Danes.

Zobel DP, Andreasen CH, Grarup N, Eiberg H, Sørensen TI, Sandbaek A, Lauritzen T, Borch-Johnsen K, Jørgensen T, Pedersen O, Hansen T.

Diabetes. 2009 Mar;58(3):757-64. Epub 2008 Dec 10.PMID: 19073769 [PubMed - indexed for MEDLINE]Related articlesFree article

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk.

Bouatia-Naji N, Bonnefond A, Cavalcanti-Proença C, Sparsø T, Holmkvist J, Marchand M, Delplanque J, Lobbens S, Rocheleau G, Durand E, De Graeve F, Chèvre JC, Borch-Johnsen K, Hartikainen AL, Ruokonen A, Tichet J, Marre M, Weill J, Heude B, Tauber M, Lemaire K, Schuit F, Elliott P, Jørgensen T, Charpentier G, Hadjadj S, Cauchi S, Vaxillaire M, Sladek R, Visvikis-Siest S, Balkau B, Lévy-Marchal C, Pattou F, Meyre D, Blakemore AI, Jarvelin MR, Walley AJ, Hansen T, Dina C, Pedersen O, Froguel P.

Nat Genet. 2009 Jan;41(1):89-94. Epub 2008 Dec 7.PMID: 19060909 [PubMed - indexed for MEDLINE]Related articles

Lung function as a predictor of survival in very elderly people: the Danish 1905 cohort study.

Jacobsen PK, Sigsgaard T, Pedersen OF, Christensen K, Miller MR.

J Am Geriatr Soc. 2008 Nov;56(11):2150-2. No abstract available. PMID: 19016953 [PubMed - indexed for MEDLINE]Related articles

Improved survival prediction from lung function data in a large population sample.

Miller MR, Pedersen OF, Lange P, Vestbo J.

Respir Med. 2009 Mar;103(3):442-8. Epub 2008 Nov 6.PMID: 18993043 [PubMed - indexed for MEDLINE]Related articles

Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies.

Friedrich B, Weyrich P, Stancáková A, Wang J, Kuusisto J, Laakso M, Sesti G, Succurro E, Smith U, Hansen T, Pedersen O, Machicao F, Schäfer S, Lang F, Risler T, Ullrich S, Stefan N, Fritsche A, Häring HU.

PLoS One. 2008;3(11):e3506. Epub 2008 Nov 5.PMID: 18985156 [PubMed - indexed for MEDLINE]Related articlesFree article