PubMed

Dual modulation of both lipid oxidation and synthesis by peroxisome proliferator-activated receptor-{gamma} coactivator-1{alpha} and -1{beta} in cultured myotubes.

Espinoza DO, Boros LG, Crunkhorn S, Gami H, Patti ME.

FASEB J. 2009 Nov 11. [Epub ahead of print]PMID: 19906680 [PubMed - as supplied by publisher]Related articles

Thyroid hormone-related regulation of gene expression in human fatty liver.

Pihlajamäki J, Boes T, Kim EY, Dearie F, Kim BW, Schroeder J, Mun E, Nasser I, Park PJ, Bianco AC, Goldfine AB, Patti ME.

J Clin Endocrinol Metab. 2009 Sep;94(9):3521-9. Epub 2009 Jun 23.PMID: 19549744 [PubMed - indexed for MEDLINE]Related articles

Ablation of ARNT/HIF1beta in liver alters gluconeogenesis, lipogenic gene expression, and serum ketones.

Wang XL, Suzuki R, Lee K, Tran T, Gunton JE, Saha AK, Patti ME, Goldfine A, Ruderman NB, Gonzalez FJ, Kahn CR.

Cell Metab. 2009 May;9(5):428-39. Erratum in: Cell Metab. 2009 Jun;9(6):565. PMID: 19416713 [PubMed - indexed for MEDLINE]Related articles

Best practice updates for multidisciplinary care in weight loss surgery.

Apovian CM, Cummings S, Anderson W, Borud L, Boyer K, Day K, Hatchigian E, Hodges B, Patti ME, Pettus M, Perna F, Rooks D, Saltzman E, Skoropowski J, Tantillo MB, Thomason P.

Obesity (Silver Spring). 2009 May;17(5):871-9. Epub 2009 Feb 19.PMID: 19396065 [PubMed - indexed for MEDLINE]Related articles

Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism.

Patti ME, Houten SM, Bianco AC, Bernier R, Larsen PR, Holst JJ, Badman MK, Maratos-Flier E, Mun EC, Pihlajamaki J, Auwerx J, Goldfine AB.

Obesity (Silver Spring). 2009 Sep;17(9):1671-7. Epub 2009 Apr 9.PMID: 19360006 [PubMed - indexed for MEDLINE]Related articles

Zinc finger protein Zbtb20 is essential for postnatal survival and glucose homeostasis.

Sutherland AP, Zhang H, Zhang Y, Michaud M, Xie Z, Patti ME, Grusby MJ, Zhang WJ.

Mol Cell Biol. 2009 May;29(10):2804-15. Epub 2009 Mar 9.PMID: 19273596 [PubMed - indexed for MEDLINE]Related articlesFree article

Accelerated postnatal growth increases lipogenic gene expression and adipocyte size in low-birth weight mice.

Isganaitis E, Jimenez-Chillaron J, Woo M, Chow A, DeCoste J, Vokes M, Liu M, Kasif S, Zavacki AM, Leshan RL, Myers MG, Patti ME.

Diabetes. 2009 May;58(5):1192-200. Epub 2009 Feb 10.PMID: 19208909 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic determinants and molecular pathways in the pathogenesis of Type 2 diabetes.

Jin W, Patti ME.

Clin Sci (Lond). 2009 Jan;116(2):99-111. Review.PMID: 19076063 [PubMed - indexed for MEDLINE]Related articles

Type 2 deiodinase expression is induced by peroxisomal proliferator-activated receptor-gamma agonists in skeletal myocytes.

Grozovsky R, Ribich S, Rosene ML, Mulcahey MA, Huang SA, Patti ME, Bianco AC, Kim BW.

Endocrinology. 2009 Apr;150(4):1976-83. Epub 2008 Nov 26. Erratum in: Endocrinology. 2009 May;150(5):2499. PMID: 19036883 [PubMed - indexed for MEDLINE]Related articles

Intergenerational transmission of glucose intolerance and obesity by in utero undernutrition in mice.

Jimenez-Chillaron JC, Isganaitis E, Charalambous M, Gesta S, Pentinat-Pelegrin T, Faucette RR, Otis JP, Chow A, Diaz R, Ferguson-Smith A, Patti ME.

Diabetes. 2009 Feb;58(2):460-8. Epub 2008 Nov 18.PMID: 19017762 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin regulates SOCS2 expression and the mitogenic effect of IGF-1 in mesangial cells.

Isshiki K, He Z, Maeno Y, Ma RC, Yasuda Y, Kuroki T, White GS, Patti ME, Weir GC, King GL.

Kidney Int. 2008 Dec;74(11):1434-43. Epub 2008 Aug 13.PMID: 19008912 [PubMed - indexed for MEDLINE]Related articlesFree article

The emerging genetic architecture of type 2 diabetes.

Doria A, Patti ME, Kahn CR.

Cell Metab. 2008 Sep;8(3):186-200. Review.PMID: 18762020 [PubMed - indexed for MEDLINE]Related articles

Saturated fatty acids inhibit hepatic insulin action by modulating insulin receptor expression and post-receptor signalling.

Ruddock MW, Stein A, Landaker E, Park J, Cooksey RC, McClain D, Patti ME.

J Biochem. 2008 Nov;144(5):599-607. Epub 2008 Aug 19.PMID: 18713797 [PubMed - indexed for MEDLINE]Related articles

Diabetes risk begins in utero.

Woo M, Patti ME.

Cell Metab. 2008 Jul;8(1):5-7. Review.PMID: 18590686 [PubMed - indexed for MEDLINE]Related articles

Links between thyroid hormone action, oxidative metabolism, and diabetes risk?

Crunkhorn S, Patti ME.

Thyroid. 2008 Feb;18(2):227-37. Review.PMID: 18279023 [PubMed - indexed for MEDLINE]Related articles

To catch up or not to catch up: is this the question? Lessons from animal models.

Jimenez-Chillaron JC, Patti ME.

Curr Opin Endocrinol Diabetes Obes. 2007 Feb;14(1):23-9. Review.PMID: 17940415 [PubMed - indexed for MEDLINE]Related articles

Patients with neuroglycopenia after gastric bypass surgery have exaggerated incretin and insulin secretory responses to a mixed meal.

Goldfine AB, Mun EC, Devine E, Bernier R, Baz-Hecht M, Jones DB, Schneider BE, Holst JJ, Patti ME.

J Clin Endocrinol Metab. 2007 Dec;92(12):4678-85. Epub 2007 Sep 25.PMID: 17895322 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation.

Crunkhorn S, Dearie F, Mantzoros C, Gami H, da Silva WS, Espinoza D, Faucette R, Barry K, Bianco AC, Patti ME.

J Biol Chem. 2007 May 25;282(21):15439-50. Epub 2007 Apr 6.PMID: 17416903 [PubMed - indexed for MEDLINE]Related articlesFree article

In utero undernutrition reduces diabetes incidence in non-obese diabetic mice.

Oge A, Isganaitis E, Jimenez-Chillaron J, Reamer C, Faucette R, Barry K, Przybyla R, Patti ME.

Diabetologia. 2007 May;50(5):1099-108. Epub 2007 Mar 17.PMID: 17370059 [PubMed - indexed for MEDLINE]Related articles

Effects of insulin replacements, inhibitors of angiotensin, and PKCbeta's actions to normalize cardiac gene expression and fuel metabolism in diabetic rats.

Arikawa E, Ma RC, Isshiki K, Luptak I, He Z, Yasuda Y, Maeno Y, Patti ME, Weir GC, Harris RA, Zammit VA, Tian R, King GL.

Diabetes. 2007 May;56(5):1410-20. Epub 2007 Mar 15.PMID: 17363743 [PubMed - indexed for MEDLINE]Related articlesFree article

A thin phenotype is protective for impaired glucose tolerance and related to low birth weight in mice.

Hernandez-Valencia M, Patti ME.

Arch Med Res. 2006 Oct;37(7):813-7.PMID: 16971218 [PubMed - indexed for MEDLINE]Related articles

Family history of diabetes is a major determinant of endothelial function.

Goldfine AB, Beckman JA, Betensky RA, Devlin H, Hurley S, Varo N, Schonbeck U, Patti ME, Creager MA.

J Am Coll Cardiol. 2006 Jun 20;47(12):2456-61. Epub 2006 May 30.PMID: 16781373 [PubMed - indexed for MEDLINE]Related articles

Reductions in caloric intake and early postnatal growth prevent glucose intolerance and obesity associated with low birthweight.

Jimenez-Chillaron JC, Hernandez-Valencia M, Lightner A, Faucette RR, Reamer C, Przybyla R, Ruest S, Barry K, Otis JP, Patti ME.

Diabetologia. 2006 Aug;49(8):1974-84. Epub 2006 Jun 8.PMID: 16761107 [PubMed - indexed for MEDLINE]Related articles

Computational disease gene identification: a concert of methods prioritizes type 2 diabetes and obesity candidate genes.

Tiffin N, Adie E, Turner F, Brunner HG, van Driel MA, Oti M, Lopez-Bigas N, Ouzounis C, Perez-Iratxeta C, Andrade-Navarro MA, Adeyemo A, Patti ME, Semple CA, Hide W.

Nucleic Acids Res. 2006 Jun 6;34(10):3067-81. Print 2006.PMID: 16757574 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of Rad in muscle worsens diet-induced insulin resistance and glucose intolerance and lowers plasma triglyceride level.

Ilany J, Bilan PJ, Kapur S, Caldwell JS, Patti ME, Marette A, Kahn CR.

Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4481-6. Epub 2006 Mar 14.PMID: 16537411 [PubMed - indexed for MEDLINE]Related articlesFree article

Necdin and E2F4 are modulated by rosiglitazone therapy in diabetic human adipose and muscle tissue.

Goldfine AB, Crunkhorn S, Costello M, Gami H, Landaker EJ, Niinobe M, Yoshikawa K, Lo D, Warren A, Jimenez-Chillaron J, Patti ME.

Diabetes. 2006 Mar;55(3):640-50.PMID: 16505226 [PubMed - indexed for MEDLINE]Related articlesFree article

Exercise training decreases the concentration of malonyl-CoA and increases the expression and activity of malonyl-CoA decarboxylase in human muscle.

Kuhl JE, Ruderman NB, Musi N, Goodyear LJ, Patti ME, Crunkhorn S, Dronamraju D, Thorell A, Nygren J, Ljungkvist O, Degerblad M, Stahle A, Brismar TB, Andersen KL, Saha AK, Efendic S, Bavenholm PN.

Am J Physiol Endocrinol Metab. 2006 Jun;290(6):E1296-303. Epub 2006 Jan 24.PMID: 16434556 [PubMed - indexed for MEDLINE]Related articlesFree article

Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia.

Patti ME, McMahon G, Mun EC, Bitton A, Holst JJ, Goldsmith J, Hanto DW, Callery M, Arky R, Nose V, Bonner-Weir S, Goldfine AB.

Diabetologia. 2005 Nov;48(11):2236-40. Epub 2005 Sep 30.PMID: 16195867 [PubMed - indexed for MEDLINE]Related articles

Hitting the target: leptin and perinatal nutrition in the predisposition to obesity.

Myers MG Jr, Patti ME, Leshan RL.

Endocrinology. 2005 Oct;146(10):4209-10. No abstract available. PMID: 16166232 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of total and high-molecular-weight complex of adiponectin in vascular function in offspring whose parents both had type 2 diabetes.

Halperin F, Beckman JA, Patti ME, Trujillo ME, Garvin M, Creager MA, Scherer PE, Goldfine AB.

Diabetologia. 2005 Oct;48(10):2147-54. Epub 2005 Aug 10.PMID: 16091909 [PubMed - indexed for MEDLINE]Related articles

Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin.

Tseng YH, Butte AJ, Kokkotou E, Yechoor VK, Taniguchi CM, Kriauciunas KM, Cypess AM, Niinobe M, Yoshikawa K, Patti ME, Kahn CR.

Nat Cell Biol. 2005 Jun;7(6):601-11. Epub 2005 May 15.PMID: 15895078 [PubMed - indexed for MEDLINE]Related articles

Reduced adiponectin and HDL cholesterol without elevated C-reactive protein: clues to the biology of premature atherosclerosis in Hutchinson-Gilford Progeria Syndrome.

Gordon LB, Harten IA, Patti ME, Lichtenstein AH.

J Pediatr. 2005 Mar;146(3):336-41.PMID: 15756215 [PubMed - indexed for MEDLINE]Related articles

Beta-cell secretory dysfunction in the pathogenesis of low birth weight-associated diabetes: a murine model.

Jimenez-Chillaron JC, Hernandez-Valencia M, Reamer C, Fisher S, Joszi A, Hirshman M, Oge A, Walrond S, Przybyla R, Boozer C, Goodyear LJ, Patti ME.

Diabetes. 2005 Mar;54(3):702-11.PMID: 15734846 [PubMed - indexed for MEDLINE]Related articlesFree article

Distinct pathways of insulin-regulated versus diabetes-regulated gene expression: an in vivo analysis in MIRKO mice.

Yechoor VK, Patti ME, Ueki K, Laustsen PG, Saccone R, Rauniyar R, Kahn CR.

Proc Natl Acad Sci U S A. 2004 Nov 23;101(47):16525-30. Epub 2004 Nov 16.PMID: 15546994 [PubMed - indexed for MEDLINE]Related articlesFree article

Nutrient sensor links obesity with diabetes risk.

Patti ME, Kahn BB.

Nat Med. 2004 Oct;10(10):1049-50. No abstract available. PMID: 15459705 [PubMed - indexed for MEDLINE]Related articles

Gene expression in humans with diabetes and prediabetes: what have we learned about diabetes pathophysiology?

Patti ME.

Curr Opin Clin Nutr Metab Care. 2004 Jul;7(4):383-90. Review.PMID: 15192439 [PubMed - indexed for MEDLINE]Related articles

Gene expression in the pathophysiology of type 2 diabetes mellitus.

Patti ME.

Curr Diab Rep. 2004 Jun;4(3):176-81. Review.PMID: 15132881 [PubMed - indexed for MEDLINE]Related articles

Intrinsic heterogeneity in adipose tissue of fat-specific insulin receptor knock-out mice is associated with differences in patterns of gene expression.

Blüher M, Patti ME, Gesta S, Kahn BB, Kahn CR.

J Biol Chem. 2004 Jul 23;279(30):31891-901. Epub 2004 May 6.PMID: 15131119 [PubMed - indexed for MEDLINE]Related articlesFree article

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1.

Patti ME, Butte AJ, Crunkhorn S, Cusi K, Berria R, Kashyap S, Miyazaki Y, Kohane I, Costello M, Saccone R, Landaker EJ, Goldfine AB, Mun E, DeFronzo R, Finlayson J, Kahn CR, Mandarino LJ.

Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8466-71. Epub 2003 Jun 27.PMID: 12832613 [PubMed - indexed for MEDLINE]Related articlesFree article

Sexual differentiation, pregnancy, calorie restriction, and aging affect the adipocyte-specific secretory protein adiponectin.

Combs TP, Berg AH, Rajala MW, Klebanov S, Iyengar P, Jimenez-Chillaron JC, Patti ME, Klein SL, Weinstein RS, Scherer PE.

Diabetes. 2003 Feb;52(2):268-76.PMID: 12540596 [PubMed - indexed for MEDLINE]Related articlesFree article

Coordinated patterns of gene expression for substrate and energy metabolism in skeletal muscle of diabetic mice.

Yechoor VK, Patti ME, Saccone R, Kahn CR.

Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10587-92. Epub 2002 Jul 29.PMID: 12149437 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of myasthenia gravis, myositis, and insulin-dependent diabetes mellitus by high-dose interleukin-2 in a patient with renal cell cancer.

Fraenkel PG, Rutkove SB, Matheson JK, Fowkes M, Cannon ME, Patti ME, Atkins MB, Gollob JA.

J Immunother. 2002 Jul-Aug;25(4):373-8.PMID: 12142560 [PubMed - indexed for MEDLINE]Related articles

High-fructose diet preserves beta-cell mass and prevents diabetes in nonobese diabetic mice: A potential role for increased insulin receptor substrate-2 expression.

Orban T, Landaker E, Ruan Z, Cordeman TP, Weitgasser R, Bonner-Weir S, Jackson RA, Patti ME.

Metabolism. 2001 Nov;50(11):1369-76.PMID: 11699059 [PubMed - indexed for MEDLINE]Related articles

Nutrient modulation of cellular insulin action.

Patti ME.

Ann N Y Acad Sci. 1999 Nov 18;892:187-203. Review.PMID: 10842663 [PubMed - indexed for MEDLINE]Related articles

Metabolic effects of vanadyl sulfate in humans with non-insulin-dependent diabetes mellitus: in vivo and in vitro studies.

Goldfine AB, Patti ME, Zuberi L, Goldstein BJ, LeBlanc R, Landaker EJ, Jiang ZY, Willsky GR, Kahn CR.

Metabolism. 2000 Mar;49(3):400-10.PMID: 10726921 [PubMed - indexed for MEDLINE]Related articles

Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle.

Cusi K, Maezono K, Osman A, Pendergrass M, Patti ME, Pratipanawatr T, DeFronzo RA, Kahn CR, Mandarino LJ.

J Clin Invest. 2000 Feb;105(3):311-20.PMID: 10675357 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance of early postreceptor insulin signaling events in skeletal muscle.

Patti ME, Virkamäki A, Landaker EJ, Kahn CR, Yki-Järvinen H.

Diabetes. 1999 Aug;48(8):1562-71.PMID: 10426374 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of exercise and insulin on insulin signaling proteins in human skeletal muscle.

Koval JA, Maezono K, Patti ME, Pendergrass M, DeFronzo RA, Mandarino LJ.

Med Sci Sports Exerc. 1999 Jul;31(7):998-1004.PMID: 10416561 [PubMed - indexed for MEDLINE]Related articles

The insulin receptor--a critical link in glucose homeostasis and insulin action.

Patti ME, Kahn CR.

J Basic Clin Physiol Pharmacol. 1998;9(2-4):89-109. Review.PMID: 10212828 [PubMed - indexed for MEDLINE]Related articles

Bidirectional modulation of insulin action by amino acids.

Patti ME, Brambilla E, Luzi L, Landaker EJ, Kahn CR.

J Clin Invest. 1998 Apr 1;101(7):1519-29.PMID: 9525995 [PubMed - indexed for MEDLINE]Related articlesFree article