PubMed

The pathophysiology of septic shock.

Nduka OO, Parrillo JE.

Crit Care Clin. 2009 Oct;25(4):677-702, vii.PMID: 19892247 [PubMed - in process]Related articles

Significance of arterial hypotension after resuscitation from cardiac arrest.

Trzeciak S, Jones AE, Kilgannon JH, Milcarek B, Hunter K, Shapiro NI, Hollenberg SM, Dellinger P, Parrillo JE.

Crit Care Med. 2009 Nov;37(11):2895-903; quiz 2904.PMID: 19866506 [PubMed - in process]Related articles

Initiation of inappropriate antimicrobial therapy results in a fivefold reduction of survival in human septic shock.

Kumar A, Ellis P, Arabi Y, Roberts D, Light B, Parrillo JE, Dodek P, Wood G, Kumar A, Simon D, Peters C, Ahsan M, Chateau D; Cooperative Antimicrobial Therapy of Septic Shock Database Research Group.

Chest. 2009 Nov;136(5):1237-48. Epub 2009 Aug 20.PMID: 19696123 [PubMed - in process]Related articles

Characterization of human septic sera induced gene expression modulation in human myocytes.

Hussein S, Michael P, Brabant D, Omri A, Narain R, Passi K, Ramana CV, Parrillo JE, Kumar A, Parissenti A, Kumar A.

Int J Clin Exp Med. 2009 Jun 5;2(2):131-48.PMID: 19684886 [PubMed - in process]Related articlesFree article

Microbiology, time course and clinical characteristics of infection in critically ill patients receiving packed red blood cell transfusion.

Rachoin JS, Daher R, Schorr C, Milcarek B, Parrillo JE, Gerber DR.

Vox Sang. 2009 Nov;97(4):294-302. Epub 2009 Aug 4.PMID: 19682350 [PubMed - in process]Related articles

Point-of-care assessment of microvascular blood flow in critically ill patients.

Arnold RC, Parrillo JE, Phillip Dellinger R, Chansky ME, Shapiro NI, Lundy DJ, Trzeciak S, Hollenberg SM.

Intensive Care Med. 2009 Oct;35(10):1761-6. Epub 2009 Jun 24.PMID: 19554307 [PubMed - in process]Related articles

Multicenter study of early lactate clearance as a determinant of survival in patients with presumed sepsis.

Arnold RC, Shapiro NI, Jones AE, Schorr C, Pope J, Casner E, Parrillo JE, Dellinger RP, Trzeciak S; Emergency Medicine Shock Research Network (EMShockNet) Investigators.

Shock. 2009 Jul;32(1):35-9.PMID: 19533847 [PubMed - indexed for MEDLINE]Related articles

Continuous cardiac index monitoring: A prospective observational study of agreement between a pulmonary artery catheter and a calibrated minimally invasive technique.

McCoy JV, Hollenberg SM, Dellinger RP, Arnold RC, Ruoss L, Lotano V, Peters P, Parrillo JE, Trzeciak S.

Resuscitation. 2009 Aug;80(8):893-7. Epub 2009 Jun 10.PMID: 19520480 [PubMed - indexed for MEDLINE]Related articles

Outcome measures utilized in clinical trials of interventions for post-cardiac arrest syndrome: a systematic review.

Trzeciak S, Jones AE, Kilgannon JH, Fuller BM, Roberts BW, Parrillo JE, Farrar JT.

Resuscitation. 2009 Jun;80(6):617-23. Epub 2009 Apr 21. Review.PMID: 19386408 [PubMed - indexed for MEDLINE]Related articles

Cardiogenic shock: a historical perspective.

Ginsberg F, Parrillo JE.

Crit Care Clin. 2009 Jan;25(1):103-14, viii.PMID: 19268797 [PubMed - indexed for MEDLINE]Related articles

Sepsis and septic shock: a history.

Funk DJ, Parrillo JE, Kumar A.

Crit Care Clin. 2009 Jan;25(1):83-101, viii.PMID: 19268796 [PubMed - indexed for MEDLINE]Related articles

Preface.

Kumar A, Parrillo JE.

Crit Care Clin. 2009 Jan;25(1):xiii-xiv. No abstract available. PMID: 19268791 [PubMed - indexed for MEDLINE]Related articles

Multi-Center Study of Early Lactate Clearance as a Determinant of Survival in Patients with Presumed Sepsis.

Arnold RC, Shapiro NI, Jones AE, Schorr C, Pope J, Casner E, Parrillo JE, Dellinger RP, Trzeciak S; on behalf of the Emergency Medicine Shock Research Network (EMShockNet) Investigators.

Shock. 2008 Dec 22. [Epub ahead of print]PMID: 19106806 [PubMed - as supplied by publisher]Related articles

Fluid resuscitation influences cardiovascular performance and mortality in a murine model of sepsis.

Zanotti-Cavazzoni SL, Guglielmi M, Parrillo JE, Walker T, Dellinger RP, Hollenberg SM.

Intensive Care Med. 2009 Apr;35(4):748-54. Epub 2008 Dec 9.PMID: 19066851 [PubMed - indexed for MEDLINE]Related articles

Acute kidney injury in septic shock: clinical outcomes and impact of duration of hypotension prior to initiation of antimicrobial therapy.

Bagshaw SM, Lapinsky S, Dial S, Arabi Y, Dodek P, Wood G, Ellis P, Guzman J, Marshall J, Parrillo JE, Skrobik Y, Kumar A; Cooperative Antimicrobial Therapy of Septic Shock (CATSS) Database Research Group.

Intensive Care Med. 2009 May;35(5):871-81. Epub 2008 Dec 9.PMID: 19066848 [PubMed - indexed for MEDLINE]Related articles

Multi-Center Study of Early Lactate Clearance as a Determinant of Survival in Patients with Presumed Sepsis.

Arnold RC, Shapiro NI, Jones AE, Schorr C, Pope J, Casner E, Parrillo JE, Dellinger RP; Error! Bookmark not defined. on behalf of the Emergency Medicine Shock Research Network (EMShockNet) Investigators.

Shock. 2008 Dec 4. [Epub ahead of print]PMID: 19060782 [PubMed - as supplied by publisher]Related articles

Clinical characteristics and outcomes of septic patients with new-onset atrial fibrillation.

Christian SA, Schorr C, Ferchau L, Jarbrink ME, Parrillo JE, Gerber DR.

J Crit Care. 2008 Dec;23(4):532-6.PMID: 19056018 [PubMed - indexed for MEDLINE]Related articles

Early arterial hypotension is common in the post-cardiac arrest syndrome and associated with increased in-hospital mortality.

Kilgannon JH, Roberts BW, Reihl LR, Chansky ME, Jones AE, Dellinger RP, Parrillo JE, Trzeciak S.

Resuscitation. 2008 Dec;79(3):410-6. Epub 2008 Nov 5.PMID: 18990478 [PubMed - indexed for MEDLINE]Related articles

Assessment of asymmetric lung disease in intensive care unit patients using vibration response imaging.

Jean S, Cinel I, Tay C, Parrillo JE, Dellinger RP.

Anesth Analg. 2008 Oct;107(4):1243-7.PMID: 18806034 [PubMed - indexed for MEDLINE]Related articlesFree article

Use of a standardized order set for achieving target temperature in the implementation of therapeutic hypothermia after cardiac arrest: a feasibility study.

Kilgannon JH, Roberts BW, Stauss M, Cimino MJ, Ferchau L, Chansky ME, Dellinger RP, Parrillo JE, Trzeciak S.

Acad Emerg Med. 2008 Jun;15(6):499-505.PMID: 18616434 [PubMed - indexed for MEDLINE]Related articles

Early increases in microcirculatory perfusion during protocol-directed resuscitation are associated with reduced multi-organ failure at 24 h in patients with sepsis.

Trzeciak S, McCoy JV, Phillip Dellinger R, Arnold RC, Rizzuto M, Abate NL, Shapiro NI, Parrillo JE, Hollenberg SM; Microcirculatory Alterations in Resuscitation and Shock (MARS) investigators.

Intensive Care Med. 2008 Dec;34(12):2210-7. Epub 2008 Jul 2.PMID: 18594793 [PubMed - indexed for MEDLINE]Related articles

The golden hour of right ventricular ischemia.

Yen AD, Parrillo JE.

Crit Care Med. 2008 Jul;36(7):2194-5. No abstract available. PMID: 18594227 [PubMed - indexed for MEDLINE]Related articles

Image-based monitoring of one-lung ventilation.

Jean S, Cinel I, Gratz I, Tay C, Lotano V, Deal E, Parrillo JE, Dellinger RP.

Eur J Anaesthesiol. 2008 Dec;25(12):995-1001. Epub 2008 May 20.PMID: 18492316 [PubMed - indexed for MEDLINE]Related articles

Resuscitating the microcirculation in sepsis: the central role of nitric oxide, emerging concepts for novel therapies, and challenges for clinical trials.

Trzeciak S, Cinel I, Phillip Dellinger R, Shapiro NI, Arnold RC, Parrillo JE, Hollenberg SM; Microcirculatory Alterations in Resuscitation and Shock (MARS) Investigators.

Acad Emerg Med. 2008 May;15(5):399-413. Review.PMID: 18439194 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiovascular response to dobutamine stress predicts outcome in severe sepsis and septic shock.

Kumar A, Schupp E, Bunnell E, Ali A, Milcarek B, Parrillo JE.

Crit Care. 2008;12(2):R35. Epub 2008 Mar 4.PMID: 18318900 [PubMed - indexed for MEDLINE]Related articlesFree article

Case report: vibration response imaging findings following inadvertent esophageal intubation.

Cinel I, Jean S, Tay C, Gratz I, Deal E, Parrillo JE, Dellinger RP.

Can J Anaesth. 2008 Mar;55(3):172-6.PMID: 18310628 [PubMed - indexed for MEDLINE]Related articles

Septic shock--vasopressin, norepinephrine, and urgency.

Parrillo JE.

N Engl J Med. 2008 Feb 28;358(9):954-6. No abstract available. PMID: 18305271 [PubMed - indexed for MEDLINE]Related articles

Cardiogenic shock.

Topalian S, Ginsberg F, Parrillo JE.

Crit Care Med. 2008 Jan;36(1 Suppl):S66-74. Review.PMID: 18158480 [PubMed - indexed for MEDLINE]Related articles

Discordance between microvascular permeability and leukocyte dynamics in septic inducible nitric oxide synthase deficient mice.

Hollenberg SM, Guglielmi M, Parrillo JE.

Crit Care. 2007;11(6):R125.PMID: 18062823 [PubMed - indexed for MEDLINE]Related articlesFree article

Dynamic visualization of lung sounds with a vibration response device: a case series.

Dellinger RP, Parrillo JE, Kushnir A, Rossi M, Kushnir I.

Respiration. 2008;75(1):60-72. Epub 2007 Jun 4.PMID: 17551264 [PubMed - indexed for MEDLINE]Related articles

Effect of nitric oxide synthase inhibition on haemodynamics and outcome of patients with persistent cardiogenic shock complicating acute myocardial infarction: a phase II dose-ranging study.

Dzavík V, Cotter G, Reynolds HR, Alexander JH, Ramanathan K, Stebbins AL, Hathaway D, Farkouh ME, Ohman EM, Baran DA, Prondzinsky R, Panza JA, Cantor WJ, Vered Z, Buller CE, Kleiman NS, Webb JG, Holmes DR, Parrillo JE, Hazen SL, Gross SS, Harrington RA, Hochman JS; SHould we inhibit nitric Oxide synthase in Cardiogenic shocK 2 (SHOCK-2) investigators.

Eur Heart J. 2007 May;28(9):1109-16. Epub 2007 Apr 25.PMID: 17459901 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum lactate as a predictor of mortality in patients with infection.

Trzeciak S, Dellinger RP, Chansky ME, Arnold RC, Schorr C, Milcarek B, Hollenberg SM, Parrillo JE.

Intensive Care Med. 2007 Jun;33(6):970-7. Epub 2007 Mar 13.PMID: 17431582 [PubMed - indexed for MEDLINE]Related articles

Eosinophilic myocarditis.

Ginsberg F, Parrillo JE.

Heart Fail Clin. 2005 Oct;1(3):419-29. Review. No abstract available. PMID: 17386864 [PubMed - indexed for MEDLINE]Related articles

Regional distribution of acoustic-based lung vibration as a function of mechanical ventilation mode.

Dellinger RP, Jean S, Cinel I, Tay C, Rajanala S, Glickman YA, Parrillo JE.

Crit Care. 2007;11(1):R26.PMID: 17316449 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitric oxide-dependent and -independent mechanisms are involved in TNF-alpha -induced depression of cardiac myocyte contractility.

Kumar A, Paladugu B, Mensing J, Kumar A, Parrillo JE.

Am J Physiol Regul Integr Comp Physiol. 2007 May;292(5):R1900-6. Epub 2007 Jan 18.PMID: 17234961 [PubMed - indexed for MEDLINE]Related articles

Transforming growth factor-beta1 blocks in vitro cardiac myocyte depression induced by tumor necrosis factor-alpha, interleukin-1beta, and human septic shock serum.

Kumar A, Kumar A, Paladugu B, Mensing J, Parrillo JE.

Crit Care Med. 2007 Feb;35(2):358-64.PMID: 17204997 [PubMed - indexed for MEDLINE]Related articles

Early microcirculatory perfusion derangements in patients with severe sepsis and septic shock: relationship to hemodynamics, oxygen transport, and survival.

Trzeciak S, Dellinger RP, Parrillo JE, Guglielmi M, Bajaj J, Abate NL, Arnold RC, Colilla S, Zanotti S, Hollenberg SM; Microcirculatory Alterations in Resuscitation and Shock Investigators.

Ann Emerg Med. 2007 Jan;49(1):88-98, 98.e1-2. Epub 2006 Nov 7.PMID: 17095120 [PubMed - indexed for MEDLINE]Related articles

Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock.

Kumar A, Roberts D, Wood KE, Light B, Parrillo JE, Sharma S, Suppes R, Feinstein D, Zanotti S, Taiberg L, Gurka D, Kumar A, Cheang M.

Crit Care Med. 2006 Jun;34(6):1589-96.PMID: 16625125 [PubMed - indexed for MEDLINE]Related articles

Translating research to clinical practice: a 1-year experience with implementing early goal-directed therapy for septic shock in the emergency department.

Trzeciak S, Dellinger RP, Abate NL, Cowan RM, Stauss M, Kilgannon JH, Zanotti S, Parrillo JE.

Chest. 2006 Feb;129(2):225-32.PMID: 16478835 [PubMed - indexed for MEDLINE]Related articlesFree article

The future of hospital economic health.

Gerber DR, Bekes CE, Parrillo JE.

Crit Care Med. 2006 Mar;34(3 Suppl):S88-93. Review.PMID: 16477210 [PubMed - indexed for MEDLINE]Related articles

Economics of critical care: Medicare part A versus part B payments.

Gerber DR, Bekes CE, Parrillo JE.

Crit Care Med. 2006 Mar;34(3 Suppl):S82-7. Review.PMID: 16477209 [PubMed - indexed for MEDLINE]Related articles

Porcine models of severe sepsis: emphasis on porcine peritonitis.

Goldfarb RD, Dellinger RP, Parrillo JE.

Shock. 2005 Dec;24 Suppl 1:75-81. Review. No abstract available. PMID: 16374377 [PubMed - indexed for MEDLINE]Related articles

The duration of hypotension before the initiation of antibiotic treatment is a critical determinant of survival in a murine model of Escherichia coli septic shock: association with serum lactate and inflammatory cytokine levels.

Kumar A, Haery C, Paladugu B, Kumar A, Symeoneides S, Taiberg L, Osman J, Trenholme G, Opal SM, Goldfarb R, Parrillo JE.

J Infect Dis. 2006 Jan 15;193(2):251-8. Epub 2005 Dec 13.PMID: 16362889 [PubMed - indexed for MEDLINE]Related articles

Complement.

Goldfarb RD, Parrillo JE.

Crit Care Med. 2005 Dec;33(12 Suppl):S482-4. Review. No abstract available. PMID: 16340428 [PubMed - indexed for MEDLINE]Related articles

Human serum from patients with septic shock activates transcription factors STAT1, IRF1, and NF-kappaB and induces apoptosis in human cardiac myocytes.

Kumar A, Kumar A, Michael P, Brabant D, Parissenti AM, Ramana CV, Xu X, Parrillo JE.

J Biol Chem. 2005 Dec 30;280(52):42619-26. Epub 2005 Oct 13.PMID: 16223733 [PubMed - indexed for MEDLINE]Related articlesFree article

Severe sepsis and therapy with activated protein C.

Parrillo JE.

N Engl J Med. 2005 Sep 29;353(13):1398-400. No abstract available. Erratum in: N Engl J Med. 2005 Nov 24;353(21):2311. PMID: 16192486 [PubMed - indexed for MEDLINE]Related articles

Our Journal, Critical Care Medicine, in 2005: high impact factor, rapid manuscript review, growing submissions, and widespread distribution.

Parrillo JE.

Crit Care Med. 2005 May;33(5):923-4. No abstract available. PMID: 15891314 [PubMed - indexed for MEDLINE]Related articles

Neutralization of endotoxin by a phospholipid emulsion in healthy volunteers.

Gordon BR, Parker TS, Levine DM, Feuerbach F, Saal SD, Sloan BJ, Chu C, Stenzel KH, Parrillo JE, Rubin AL.

J Infect Dis. 2005 May 1;191(9):1515-22. Epub 2005 Mar 24.PMID: 15809911 [PubMed - indexed for MEDLINE]Related articles

The effect of percutaneous transmyocardial laser revascularization on left ventricular function in a porcine model of hibernating myocardium: a pilot study.

Almeda FQ, Glock D, Sandelski J, Ibrahim O, Macioch JE, Allen T, Dainauskas JR, Parrillo JE, Snell RJ, Schaer GL.

Cardiovasc Radiat Med. 2004 Jul-Sep;5(3):132-5.PMID: 15721848 [PubMed - indexed for MEDLINE]Related articles

Interleukin-10 blunts the human inflammatory response to lipopolysaccharide without affecting the cardiovascular response.

Kumar A, Zanotti S, Bunnell G, Habet K, Añel R, Neumann A, Cheang M, Dinarello CA, Cutler D, Parrillo JE.

Crit Care Med. 2005 Feb;33(2):331-40.PMID: 15699836 [PubMed - indexed for MEDLINE]Related articles