PubMed

Human airway smooth muscle is structurally and mechanically similar to that of other species.

Chin LY, Bossé Y, Jiao Y, Solomon D, Hackett TL, Paré PD, Seow CY.

Eur Respir J. 2009 Nov 19. [Epub ahead of print]PMID: 19926737 [PubMed - as supplied by publisher]Related articles

Genetics and genomics of chronic obstructive pulmonary disease.

Silverman EK, Spira A, Paré PD.

Proc Am Thorac Soc. 2009 Sep 15;6(6):539-42.PMID: 19741265 [PubMed - in process]Related articlesFree article

Prediction of the rate of decline in FEV(1) in smokers using quantitative Computed Tomography.

Yuan R, Hogg JC, Paré PD, Sin DD, Wong JC, Nakano Y, McWilliams AM, Lam S, Coxson HO.

Thorax. 2009 Nov;64(11):944-9. Epub 2009 Sep 3.PMID: 19734130 [PubMed - in process]Related articles

Modifier gene study of meconium ileus in cystic fibrosis: statistical considerations and gene mapping results.

Dorfman R, Li W, Sun L, Lin F, Wang Y, Sandford A, Paré PD, McKay K, Kayserova H, Piskackova T, Macek M, Czerska K, Sands D, Tiddens H, Margarit S, Repetto G, Sontag MK, Accurso FJ, Blackman S, Cutting GR, Tsui LC, Corey M, Durie P, Zielenski J, Strug LJ.

Hum Genet. 2009 Aug 7. [Epub ahead of print]PMID: 19662435 [PubMed - as supplied by publisher]Related articles

Sex Differences in Emphysema and Airway Disease in Smokers.

Camp PG, Coxson HO, Levy RD, Pillai S, Anderson W, Vestbo J, Kennedy SM, Silverman EK, Lomas DA, Paré PD.

Chest. 2009 Jul 17. [Epub ahead of print]PMID: 19617404 [PubMed - as supplied by publisher]Related articles

Lack of association of TIM3 polymorphisms and allergic phenotypes.

Zhang J, Daley D, Akhabir L, Stefanowicz D, Chan-Yeung M, Becker AB, Laprise C, Paré PD, Sandford AJ.

BMC Med Genet. 2009 Jun 30;10:62.PMID: 19566956 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of genetic susceptibility to latent adenoviral infection and decreased lung function.

Kasuga I, Hogg JC, Paré PD, Hayashi S, Sedgwick EG, Ruan J, Wallace AM, He JQ, Zhang X, Sandford AJ.

Respir Med. 2009 Nov;103(11):1672-80. Epub 2009 Jun 6.PMID: 19502044 [PubMed - in process]Related articles

Chronic Activation in Shortened Airway Smooth Muscle: A Synergistic Combination Underlying Airway Hyperresponsiveness?

Bossé Y, Chin LY, Pare PD, Seow CY.

Am J Respir Cell Mol Biol. 2009 May 15. [Epub ahead of print]PMID: 19448153 [PubMed - as supplied by publisher]Related articles

A novel study design to investigate the early-life origins of asthma in children (SAGE study).

Kozyrskyj AL, HayGlass KT, Sandford AJ, Paré PD, Chan-Yeung M, Becker AB.

Allergy. 2009 Aug;64(8):1185-93. Epub 2009 Mar 27.PMID: 19416140 [PubMed - indexed for MEDLINE]Related articles

Stress and strain in the contractile and cytoskeletal filaments of airway smooth muscle.

Deng L, Bosse Y, Brown N, Chin LY, Connolly SC, Fairbank NJ, King GG, Maksym GN, Paré PD, Seow CY, Stephen NL.

Pulm Pharmacol Ther. 2009 Oct;22(5):407-16. Epub 2009 May 4.PMID: 19409505 [PubMed - in process]Related articles

Associations of IL6 polymorphisms with lung function decline and COPD.

He JQ, Foreman MG, Shumansky K, Zhang X, Akhabir L, Sin DD, Man SF, DeMeo DL, Litonjua AA, Silverman EK, Connett JE, Anthonisen NR, Wise RA, Paré PD, Sandford AJ.

Thorax. 2009 Aug;64(8):698-704. Epub 2009 Apr 8.PMID: 19359268 [PubMed - in process]Related articles

Analyses of associations with asthma in four asthma population samples from Canada and Australia.

Daley D, Lemire M, Akhabir L, Chan-Yeung M, He JQ, McDonald T, Sandford A, Stefanowicz D, Tripp B, Zamar D, Bosse Y, Ferretti V, Montpetit A, Tessier MC, Becker A, Kozyrskyj AL, Beilby J, McCaskie PA, Musk B, Warrington N, James A, Laprise C, Palmer LJ, Paré PD, Hudson TJ.

Hum Genet. 2009 May;125(4):445-59. Epub 2009 Feb 27.PMID: 19247692 [PubMed - indexed for MEDLINE]Related articles

Body mass index in male patients with COPD: correlation with low attenuation areas on CT.

Ogawa E, Nakano Y, Ohara T, Muro S, Hirai T, Sato S, Sakai H, Tsukino M, Kinose D, Nishioka M, Niimi A, Chin K, Paré PD, Mishima M.

Thorax. 2009 Jan;64(1):20-5. Epub 2008 Oct 13.PMID: 18852156 [PubMed - indexed for MEDLINE]Related articles

Genetic variation in immune signaling genes differentially expressed in asthmatic lung tissues.

Tremblay K, Daley D, Chamberland A, Lemire M, Montpetit A, Laviolette M, Musk AW, James AL, Chan-Yeung M, Becker A, Kozyrskyj AL, Sandford AJ, Hudson TJ, Paré PD, Laprise C.

J Allergy Clin Immunol. 2008 Sep;122(3):529-36.e17.PMID: 18774388 [PubMed - indexed for MEDLINE]Related articles

Adaptation of airway smooth muscle to basal tone: relevance to airway hyperresponsiveness.

Bossé Y, Chin LY, Paré PD, Seow CY.

Am J Respir Cell Mol Biol. 2009 Jan;40(1):13-8. Epub 2008 Jul 10.PMID: 18617678 [PubMed - indexed for MEDLINE]Related articles

Airway wall remodeling in asthma: from the epithelial layer to the adventitia.

Bossé Y, Paré PD, Seow CY.

Curr Allergy Asthma Rep. 2008 Jul;8(4):357-66. Review.PMID: 18606090 [PubMed - indexed for MEDLINE]Related articles

Airway wall thickening and emphysema show independent familial aggregation in chronic obstructive pulmonary disease.

Patel BD, Coxson HO, Pillai SG, Agustí AG, Calverley PM, Donner CF, Make BJ, Müller NL, Rennard SI, Vestbo J, Wouters EF, Hiorns MP, Nakano Y, Camp PG, Nasute Fauerbach PV, Screaton NJ, Campbell EJ, Anderson WH, Paré PD, Levy RD, Lake SL, Silverman EK, Lomas DA; International COPD Genetics Network.

Am J Respir Crit Care Med. 2008 Sep 1;178(5):500-5. Epub 2008 Jun 19.PMID: 18565956 [PubMed - indexed for MEDLINE]Related articlesFree article

Selection of housekeeping genes for real-time PCR in atopic human bronchial epithelial cells.

He JQ, Sandford AJ, Wang IM, Stepaniants S, Knight DA, Kicic A, Stick SM, Paré PD.

Eur Respir J. 2008 Sep;32(3):755-62. Epub 2008 Apr 16.PMID: 18417509 [PubMed - indexed for MEDLINE]Related articles

Association of genetic variations in the CSF2 and CSF3 genes with lung function in smoking-induced COPD.

He JQ, Shumansky K, Connett JE, Anthonisen NR, Paré PD, Sandford AJ.

Eur Respir J. 2008 Jul;32(1):25-34. Epub 2008 Mar 19.PMID: 18353856 [PubMed - indexed for MEDLINE]Related articles

Complex two-gene modulation of lung disease severity in children with cystic fibrosis.

Dorfman R, Sandford A, Taylor C, Huang B, Frangolias D, Wang Y, Sang R, Pereira L, Sun L, Berthiaume Y, Tsui LC, Paré PD, Durie P, Corey M, Zielenski J.

J Clin Invest. 2008 Mar;118(3):1040-9.PMID: 18292811 [PubMed - indexed for MEDLINE]Related articlesFree article

Matrix metalloproteinase expression by human alveolar macrophages in relation to emphysema.

Wallace AM, Sandford AJ, English JC, Burkett KM, Li H, Finley RJ, Müller NL, Coxson HO, Paré PD, Abboud RT.

COPD. 2008 Feb;5(1):13-23.PMID: 18259971 [PubMed - indexed for MEDLINE]Related articles

Recent advances in asthma genetics.

Zhang J, Paré PD, Sandford AJ.

Respir Res. 2008 Jan 15;9:4. Review.PMID: 18197984 [PubMed - indexed for MEDLINE]Related articlesFree article

Length adaptation of airway smooth muscle.

Bossé Y, Sobieszek A, Paré PD, Seow CY.

Proc Am Thorac Soc. 2008 Jan 1;5(1):62-7. Review.PMID: 18094086 [PubMed - indexed for MEDLINE]Related articlesFree article

Understanding the biological differences in susceptibility to chronic obstructive pulmonary disease between men and women.

Sin DD, Cohen SB, Day A, Coxson H, Paré PD.

Proc Am Thorac Soc. 2007 Dec;4(8):671-4. Review.PMID: 18073400 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene expression profiling in patients with chronic obstructive pulmonary disease and lung cancer.

Wang IM, Stepaniants S, Boie Y, Mortimer JR, Kennedy B, Elliott M, Hayashi S, Loy L, Coulter S, Cervino S, Harris J, Thornton M, Raubertas R, Roberts C, Hogg JC, Crackower M, O'Neill G, Paré PD.

Am J Respir Crit Care Med. 2008 Feb 15;177(4):402-11. Epub 2007 Nov 1.PMID: 17975202 [PubMed - indexed for MEDLINE]Related articlesFree article

Ultrastructural basis of airway smooth muscle contraction.

Seow CY, Paré PD.

Can J Physiol Pharmacol. 2007 Jul;85(7):659-65. Review.PMID: 17823629 [PubMed - indexed for MEDLINE]Related articles

Structural basis for exaggerated airway narrowing.

Paré PD, McParland BE, Seow CY.

Can J Physiol Pharmacol. 2007 Jul;85(7):653-8. Review.PMID: 17823628 [PubMed - indexed for MEDLINE]Related articles

Physical integrity of smooth muscle myosin filaments is enhanced by phosphorylation of the regulatory myosin light chain.

Ip K, Sobieszek A, Solomon D, Jiao Y, Paré PD, Seow CY.

Cell Physiol Biochem. 2007;20(5):649-58.PMID: 17762191 [PubMed - indexed for MEDLINE]Related articles

Promoter polymorphism and expression of beta-arrestin 2 in neutrophils.

Zhang X, He JQ, Ding L, Paré PD, Sandford AJ.

Clin Chim Acta. 2007 Oct;385(1-2):79-80. Epub 2007 Jul 31. No abstract available. PMID: 17761157 [PubMed - indexed for MEDLINE]Related articles

The effects of radiation dose and CT manufacturer on measurements of lung densitometry.

Yuan R, Mayo JR, Hogg JC, Paré PD, McWilliams AM, Lam S, Coxson HO.

Chest. 2007 Aug;132(2):617-23. Epub 2007 Jun 15.PMID: 17573501 [PubMed - indexed for MEDLINE]Related articlesFree article

Survival after lung volume reduction in chronic obstructive pulmonary disease: insights from small airway pathology.

Hogg JC, Chu FS, Tan WC, Sin DD, Patel SA, Pare PD, Martinez FJ, Rogers RM, Make BJ, Criner GJ, Cherniack RM, Sharafkhaneh A, Luketich JD, Coxson HO, Elliott WM, Sciurba FC.

Am J Respir Crit Care Med. 2007 Sep 1;176(5):454-9. Epub 2007 Jun 7.PMID: 17556723 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanism of partial adaptation in airway smooth muscle after a step change in length.

Ali F, Chin L, Paré PD, Seow CY.

J Appl Physiol. 2007 Aug;103(2):569-77. Epub 2007 May 10.PMID: 17495118 [PubMed - indexed for MEDLINE]Related articlesFree article

Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma.

An SS, Bai TR, Bates JH, Black JL, Brown RH, Brusasco V, Chitano P, Deng L, Dowell M, Eidelman DH, Fabry B, Fairbank NJ, Ford LE, Fredberg JJ, Gerthoffer WT, Gilbert SH, Gosens R, Gunst SJ, Halayko AJ, Ingram RH, Irvin CG, James AL, Janssen LJ, King GG, Knight DA, Lauzon AM, Lakser OJ, Ludwig MS, Lutchen KR, Maksym GN, Martin JG, Mauad T, McParland BE, Mijailovich SM, Mitchell HW, Mitchell RW, Mitzner W, Murphy TM, Paré PD, Pellegrino R, Sanderson MJ, Schellenberg RR, Seow CY, Silveira PS, Smith PG, Solway J, Stephens NL, Sterk PJ, Stewart AG, Tang DD, Tepper RS, Tran T, Wang L.

Eur Respir J. 2007 May;29(5):834-60. Review.PMID: 17470619 [PubMed - indexed for MEDLINE]Related articlesFree article

Single-nucleotide polymorphisms and lung disease: clinical implications.

Tebbutt SJ, James A, Paré PD.

Chest. 2007 Apr;131(4):1216-23. Review.PMID: 17426230 [PubMed - indexed for MEDLINE]Related articlesFree article

The growing burden of chronic obstructive pulmonary disease and lung cancer in women: examining sex differences in cigarette smoke metabolism.

Ben-Zaken Cohen S, Paré PD, Man SF, Sin DD.

Am J Respir Crit Care Med. 2007 Jul 15;176(2):113-20. Epub 2007 Apr 5. Review.PMID: 17413125 [PubMed - indexed for MEDLINE]Related articlesFree article

PMN degranulation in relation to CD63 expression and genetic polymorphisms in healthy individuals and COPD patients.

Zhang XZ, Paré PD, Sandford AJ.

Int J Mol Med. 2007 May;19(5):817-22.PMID: 17390088 [PubMed - indexed for MEDLINE]Related articles

The association between small airway obstruction and emphysema phenotypes in COPD.

Kim WD, Ling SH, Coxson HO, English JC, Yee J, Levy RD, Paré PD, Hogg JC.

Chest. 2007 May;131(5):1372-8. Epub 2007 Feb 22.PMID: 17317735 [PubMed - indexed for MEDLINE]Related articlesFree article

Acetylcholine-induced asynchronous calcium waves in intact human bronchial muscle bundle.

Dai JM, Kuo KH, Leo JM, Paré PD, van Breemen C, Lee CH.

Am J Respir Cell Mol Biol. 2007 May;36(5):600-8. Epub 2006 Dec 14.PMID: 17170384 [PubMed - indexed for MEDLINE]Related articlesFree article

A lung tissue bank for gene expression studies in chronic obstructive pulmonary disease.

Ding L, Quinlan KB, Elliott WM, Hamodat M, Paré PD, Hogg JC, Hayashi S.

COPD. 2004;1(2):191-204.PMID: 17136987 [PubMed - indexed for MEDLINE]Related articles

Transforming growth factor-beta1 polymorphisms, airway responsiveness and lung function decline in smokers.

Ogawa E, Ruan J, Connett JE, Anthonisen NR, Paré PD, Sandford AJ.

Respir Med. 2007 May;101(5):938-43. Epub 2006 Oct 27.PMID: 17071067 [PubMed - indexed for MEDLINE]Related articles

Association of Hck genetic polymorphisms with gene expression and COPD.

Zhang X, Mahmudi-Azer S, Connett JE, Anthonisen NR, He JQ, Paré PD, Sandford AJ.

Hum Genet. 2007 Jan;120(5):681-90. Epub 2006 Sep 26.PMID: 17024369 [PubMed - indexed for MEDLINE]Related articles

Tumour necrosis factor and lymphotoxin A polymorphisms and lung function in smokers.

Tanaka G, Sandford AJ, Burkett K, Connett JE, Anthonisen NR, Paré PD, He JQ.

Eur Respir J. 2007 Jan;29(1):34-41. Epub 2006 Sep 13.PMID: 16971410 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationship of matrix metalloproteinase mRNA expression and genetic polymorphisms to emphysema.

Abboud RT, Wallace AM, English JC, Müller NL, Coxson H, Paré PD, Sandford AJ.

Proc Am Thorac Soc. 2006 Aug;3(6):475. No abstract available. PMID: 16921111 [PubMed - indexed for MEDLINE]Related articlesFree article

Contribution of alpha- and beta-defensins to lung function decline and infection in smokers: an association study.

Wallace AM, He JQ, Burkett KM, Ruan J, Connett JE, Anthonisen NR, Paré PD, Sandford AJ.

Respir Res. 2006 May 15;7:76.PMID: 16700921 [PubMed - indexed for MEDLINE]Related articlesFree article

Variants in the glutamate-cysteine-ligase gene are associated with cystic fibrosis lung disease.

McKone EF, Shao J, Frangolias DD, Keener CL, Shephard CA, Farin FM, Tonelli MR, Pare PD, Sandford AJ, Aitken ML, Kavanagh TJ.

Am J Respir Crit Care Med. 2006 Aug 15;174(4):415-9. Epub 2006 May 11.PMID: 16690975 [PubMed - indexed for MEDLINE]Related articlesFree article

Bronchiolitis obliterans following lung transplantation: early detection using computed tomographic scanning.

de Jong PA, Dodd JD, Coxson HO, Storness-Bliss C, Paré PD, Mayo JR, Levy RD.

Thorax. 2006 Sep;61(9):799-804. Epub 2006 May 2.PMID: 16670170 [PubMed - indexed for MEDLINE]Related articlesFree article

Interferon gamma polymorphisms and their interaction with smoking are associated with lung function.

He JQ, Burkett K, Connett JE, Anthonisen NR, Paré PD, Sandford AJ.

Hum Genet. 2006 May;119(4):365-75. Epub 2006 Feb 11.PMID: 16474934 [PubMed - indexed for MEDLINE]Related articles

Stability of housekeeping genes in alveolar macrophages from COPD patients.

Ishii T, Wallace AM, Zhang X, Gosselink J, Abboud RT, English JC, Paré PD, Sandford AJ.

Eur Respir J. 2006 Feb;27(2):300-6.PMID: 16452584 [PubMed - indexed for MEDLINE]Related articlesFree article

Models of contractile units and their assembly in smooth muscle.

Ali F, Paré PD, Seow CY.

Can J Physiol Pharmacol. 2005 Oct;83(10):825-31. Review.PMID: 16333353 [PubMed - indexed for MEDLINE]Related articles

The role of airway smooth muscle during an attack of asthma simulated in vitro.

McParland BE, Tait RR, Paré PD, Seow CY.

Am J Respir Cell Mol Biol. 2005 Nov;33(5):500-4. Epub 2005 Jul 29.PMID: 16055669 [PubMed - indexed for MEDLINE]Related articlesFree article