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Response to Letter to the Editor by Dullaart et al.

Havekes B, King K, Lai EW, Romjin JA, Corssmit EP, Pacak K.

Clin Endocrinol (Oxf). 2009 Nov 11. [Epub ahead of print] No abstract available. PMID: 19912244 [PubMed - as supplied by publisher]Related articles

Monoamine Oxidase A-Mediated Enhanced Catabolism of Norepinephrine Contributes to Adverse Remodeling and Pump Failure in Hearts With Pressure Overload.

Kaludercic N, Takimoto E, Nagayama T, Feng N, Lai EW, Bedja D, Chen K, Gabrielson KL, Blakely RD, Shih JC, Pacak K, Kass DA, Di Lisa F, Paolocci N.

Circ Res. 2009 Nov 12. [Epub ahead of print]PMID: 19910579 [PubMed - as supplied by publisher]Related articles

Low Sensitivity of Glucagon Provocative Testing for Diagnosis of Pheochromocytoma.

Lenders JW, Pacak K, Huynh TT, Sharabi Y, Mannelli M, Bratslavsky G, Goldstein DS, Bornstein SR, Eisenhofer G.

J Clin Endocrinol Metab. 2009 Nov 6. [Epub ahead of print]PMID: 19897672 [PubMed - as supplied by publisher]Related articles

Radiofrequency ablation of metastatic pheochromocytoma.

Venkatesan AM, Locklin J, Lai EW, Adams KT, Fojo AT, Pacak K, Wood BJ.

J Vasc Interv Radiol. 2009 Nov;20(11):1483-90.PMID: 19875067 [PubMed - in process]Related articles

Comparison of 18F-Fluoro-L-DOPA, 18F-Fluoro-Deoxyglucose, and 18F-Fluorodopamine PET and 123I-MIBG Scintigraphy in the Localization of Pheochromocytoma and Paraganglioma.

Timmers HJ, Chen CC, Carrasquillo JA, Whatley M, Ling A, Havekes B, Eisenhofer G, Martiniova L, Adams KT, Pacak K.

J Clin Endocrinol Metab. 2009 Oct 28. [Epub ahead of print]PMID: 19864450 [PubMed - as supplied by publisher]Related articles

Diagnosis, localization and treatment of pheochromocytoma in MEN 2 syndrome.

Ilias I, Pacak K.

Endocr Regul. 2009 Apr;43(2):89-93. Review.PMID: 19856714 [PubMed - indexed for MEDLINE]Related articlesFree article

Animal model of metastatic pheochromocytoma: evaluation by MRI and PET.

Martiniova L, Lai EW, Thomasson D, Kiesewetter DO, Seidel J, Merino MJ, Kvetnansky R, Pacak K.

Endocr Regul. 2009 Apr;43(2):59-64.PMID: 19856710 [PubMed - indexed for MEDLINE]Related articlesFree article

Usefulness of 123I-MIBG scintigraphy in the evaluation of patients with known or suspected primary or metastatic pheochromocytoma or paraganglioma: results from a prospective multicenter trial.

Wiseman GA, Pacak K, O'Dorisio MS, Neumann DR, Waxman AD, Mankoff DA, Heiba SI, Serafini AN, Tumeh SS, Khutoryansky N, Jacobson AF.

J Nucl Med. 2009 Sep;50(9):1448-54. Epub 2009 Aug 18.PMID: 19690028 [PubMed - indexed for MEDLINE]Related articles

Treatment of malignant pheochromocytoma.

Adjallé R, Plouin PF, Pacak K, Lehnert H.

Horm Metab Res. 2009 Sep;41(9):687-96. Epub 2009 Aug 11. Review.PMID: 19672813 [PubMed - indexed for MEDLINE]Related articles

Candidate genes associated with malignant pheochromocytomas by genome-wide expression profiling.

Suh I, Shibru D, Eisenhofer G, Pacak K, Duh QY, Clark OH, Kebebew E.

Ann Surg. 2009 Dec;250(6):983-90.PMID: 19661783 [PubMed - in process]Related articles

Successful chemotherapy of hepatic metastases in a case of succinate dehydrogenase subunit B-related paraganglioma.

He J, Makey D, Fojo T, Adams KT, Havekes B, Eisenhofer G, Sullivan P, Lai EW, Pacak K.

Endocrine. 2009 Oct;36(2):189-93. Epub 2009 Jul 18.PMID: 19618298 [PubMed - in process]Related articles

An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis.

van Nederveen FH, Gaal J, Favier J, Korpershoek E, Oldenburg RA, de Bruyn EM, Sleddens HF, Derkx P, Rivière J, Dannenberg H, Petri BJ, Komminoth P, Pacak K, Hop WC, Pollard PJ, Mannelli M, Bayley JP, Perren A, Niemann S, Verhofstad AA, de Bruïne AP, Maher ER, Tissier F, Méatchi T, Badoual C, Bertherat J, Amar L, Alataki D, Van Marck E, Ferrau F, François J, de Herder WW, Peeters MP, van Linge A, Lenders JW, Gimenez-Roqueplo AP, de Krijger RR, Dinjens WN.

Lancet Oncol. 2009 Aug;10(8):764-71. Epub 2009 Jul 1.PMID: 19576851 [PubMed - indexed for MEDLINE]Related articles

Diagnosis of pheochromocytoma with special emphasis on MEN2 syndrome.

Pacak K, Eisenhofer G, Ilias I.

Hormones (Athens). 2009 Apr-Jun;8(2):111-6. Review.PMID: 19570738 [PubMed - indexed for MEDLINE]Related articlesFree article

In vivo microCT imaging of liver lesions in small animal models.

Martiniova L, Schimel D, Lai EW, Limpuangthip A, Kvetnansky R, Pacak K.

Methods. 2009 Jun 9. [Epub ahead of print]PMID: 19520168 [PubMed - as supplied by publisher]Related articles

New imaging approaches to phaeochromocytomas and paragangliomas.

Havekes B, King K, Lai EW, Romijn JA, Corssmit EP, Pacak K.

Clin Endocrinol (Oxf). 2009 Jun 8. [Epub ahead of print]PMID: 19508681 [PubMed - as supplied by publisher]Related articles

Glucocorticoid Treatment- Effect on Adrenal Medullary Catecholamine Production.

Sharara-Chami RI, Joachim M, Pacak K, Majzoub JA.

Shock. 2009 Jun 3. [Epub ahead of print]PMID: 19503019 [PubMed - as supplied by publisher]Related articles

Overexpression of interleukin-13 receptor-alpha2 in neuroendocrine malignant pheochromocytoma: a novel target for receptor directed anti-cancer therapy.

Lai EW, Joshi BH, Martiniova L, Dogra R, Fujisawa T, Leland P, de Krijger RR, Lubensky IA, Elkahloun AG, Morris JC, Puri RK, Pacak K.

J Clin Endocrinol Metab. 2009 Aug;94(8):2952-7. Epub 2009 Jun 2.PMID: 19491224 [PubMed - indexed for MEDLINE]Related articles

Central nervous system imprinting of the G protein G(s)alpha and its role in metabolic regulation.

Chen M, Wang J, Dickerson KE, Kelleher J, Xie T, Gupta D, Lai EW, Pacak K, Gavrilova O, Weinstein LS.

Cell Metab. 2009 Jun;9(6):548-55.PMID: 19490909 [PubMed - indexed for MEDLINE]Related articles

A reduction in Pten tumor suppressor activity promotes ErbB-2-induced mouse prostate adenocarcinoma formation through the activation of signaling cascades downstream of PDK1.

Rodriguez OC, Lai EW, Vissapragada S, Cromelin C, Avetian M, Salinas P, Ramos H, Kallakury B, Casimiro M, Lisanti MP, Tanowitz HB, Pacak K, Glazer RI, Avantaggiati M, Albanese C.

Am J Pathol. 2009 Jun;174(6):2051-60. Epub 2009 May 14.PMID: 19443706 [PubMed - indexed for MEDLINE]Related articles

Penetrance and clinical consequences of a gross SDHB deletion in a large family.

Solis DC, Burnichon N, Timmers HJ, Raygada MJ, Kozupa A, Merino MJ, Makey D, Adams KT, Venisse A, Gimenez-Roqueplo AP, Pacak K.

Clin Genet. 2009 Apr;75(4):354-63.PMID: 19389109 [PubMed - indexed for MEDLINE]Related articles

Cardiac sympathetic denervation preceding motor signs in Parkinson disease.

Goldstein DS, Sharabi Y, Karp BI, Bentho O, Saleem A, Pacak K, Eisenhofer G.

Cleve Clin J Med. 2009 Apr;76 Suppl 2:S47-50.PMID: 19376983 [PubMed]Related articlesFree article

Noninvasive monitoring of a murine model of metastatic pheochromocytoma: a comparison of contrast-enhanced microCT and nonenhanced MRI.

Martiniova L, Kotys MS, Thomasson D, Schimel D, Lai EW, Bernardo M, Merino MJ, Powers JF, Ruzicka J, Kvetnansky R, Choyke PL, Pacak K.

J Magn Reson Imaging. 2009 Mar;29(3):685-91.PMID: 19243052 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms of enhanced beta-adrenergic reserve from cardiac resynchronization therapy.

Chakir K, Daya SK, Aiba T, Tunin RS, Dimaano VL, Abraham TP, Jaques-Robinson KM, Lai EW, Pacak K, Zhu WZ, Xiao RP, Tomaselli GF, Kass DA.

Circulation. 2009 Mar 10;119(9):1231-40. Epub 2009 Feb 23. Erratum in: Circulation. 2009 May 19;119(19):e533. Jacques, Kathryn [corrected to Jaques-Robinson, Kathryn M]. PMID: 19237665 [PubMed - indexed for MEDLINE]Related articles

Clinical aspects of SDHx-related pheochromocytoma and paraganglioma.

Timmers HJ, Gimenez-Roqueplo AP, Mannelli M, Pacak K.

Endocr Relat Cancer. 2009 Jun;16(2):391-400. Epub 2009 Feb 3. Review.PMID: 19190077 [PubMed - indexed for MEDLINE]Related articlesFree article

Malignant paraganglioma associated with succinate dehydrogenase subunit B in an 8-year-old child: the age of first screening?

Prodanov T, Havekes B, Nathanson KL, Adams KT, Pacak K.

Pediatr Nephrol. 2009 Jun;24(6):1239-42. Epub 2009 Feb 3.PMID: 19189136 [PubMed - indexed for MEDLINE]Related articles

Characterization of an animal model of aggressive metastatic pheochromocytoma linked to a specific gene signature.

Martiniova L, Lai EW, Elkahloun AG, Abu-Asab M, Wickremasinghe A, Solis DC, Perera SM, Huynh TT, Lubensky IA, Tischler AS, Kvetnansky R, Alesci S, Morris JC, Pacak K.

Clin Exp Metastasis. 2009;26(3):239-50. Epub 2009 Jan 25.PMID: 19169894 [PubMed - indexed for MEDLINE]Related articles

Use of 6-[18F]-fluorodopamine positron emission tomography (PET) as first-line investigation for the diagnosis and localization of non-metastatic and metastatic phaeochromocytoma (PHEO).

Timmers HJ, Eisenhofer G, Carrasquillo JA, Chen CC, Whatley M, Ling A, Adams KT, Pacak K.

Clin Endocrinol (Oxf). 2009 Jul;71(1):11-7. Epub 2008 Dec 5.PMID: 19138315 [PubMed - indexed for MEDLINE]Related articles

Brief communication: radiographic contrast infusion and catecholamine release in patients with pheochromocytoma.

Baid SK, Lai EW, Wesley RA, Ling A, Timmers HJ, Adams KT, Kozupa A, Pacak K.

Ann Intern Med. 2009 Jan 6;150(1):27-32. Erratum in: Ann Intern Med. 2009 Feb 17;150(4):292. PMID: 19124817 [PubMed - indexed for MEDLINE]Related articlesFree article

Unexplained symptomatic paroxysmal hypertension in pseudopheochromocytoma: a stress response disorder?

Eisenhofer G, Sharabi Y, Pacak K.

Ann N Y Acad Sci. 2008 Dec;1148:469-78.PMID: 19120143 [PubMed - indexed for MEDLINE]Related articles

Pheochromocytoma: an endocrine stress mimicking disorder.

Kantorovich V, Eisenhofer G, Pacak K.

Ann N Y Acad Sci. 2008 Dec;1148:462-8.PMID: 19120142 [PubMed - indexed for MEDLINE]Related articles

Detection and treatment of pheochromocytomas and paragangliomas: current standing of MIBG scintigraphy and future role of PET imaging.

Havekes B, Lai EW, Corssmit EP, Romijn JA, Timmers HJ, Pacak K.

Q J Nucl Med Mol Imaging. 2008 Dec;52(4):419-29. Review.PMID: 19088695 [PubMed - indexed for MEDLINE]Related articlesFree article

Mediastinal paragangliomas: association with mutations in the succinate dehydrogenase genes and aggressive behavior.

Ghayee HK, Havekes B, Corssmit EP, Eisenhofer G, Hammes SR, Ahmad Z, Tessnow A, Lazúrová I, Adams KT, Fojo AT, Pacak K, Auchus RJ.

Endocr Relat Cancer. 2009 Mar;16(1):291-9. Epub 2008 Dec 15.PMID: 19075037 [PubMed - indexed for MEDLINE]Related articles

A clinical overview of pheochromocytomas/paragangliomas and carcinoid tumors.

Ilias I, Pacak K.

Nucl Med Biol. 2008 Aug;35 Suppl 1:S27-34. Review.PMID: 18707631 [PubMed - indexed for MEDLINE]Related articlesFree article

Gender-related differences in the clinical presentation of malignant and benign pheochromocytoma.

Lai EW, Perera SM, Havekes B, Timmers HJ, Brouwers FM, McElroy B, Adams KT, Ohta S, Wesley RA, Eisenhofer G, Pacak K.

Endocrine. 2008 Aug-Dec;34(1-3):96-100. Epub 2008 Nov 4.PMID: 18982461 [PubMed - indexed for MEDLINE]Related articles

Differential expression of the regulated catecholamine secretory pathway in different hereditary forms of pheochromocytoma.

Eisenhofer G, Huynh TT, Elkahloun A, Morris JC, Bratslavsky G, Linehan WM, Zhuang Z, Balgley BM, Lee CS, Mannelli M, Lenders JW, Bornstein SR, Pacak K.

Am J Physiol Endocrinol Metab. 2008 Nov;295(5):E1223-33. Epub 2008 Oct 14.PMID: 18854424 [PubMed - indexed for MEDLINE]Related articlesFree article

Biochemically silent abdominal paragangliomas in patients with mutations in the succinate dehydrogenase subunit B gene.

Timmers HJ, Pacak K, Huynh TT, Abu-Asab M, Tsokos M, Merino MJ, Baysal BE, Adams KT, Eisenhofer G.

J Clin Endocrinol Metab. 2008 Dec;93(12):4826-32. Epub 2008 Oct 7.PMID: 18840642 [PubMed - indexed for MEDLINE]Related articles

Metastases but not cardiovascular mortality reduces life expectancy following surgical resection of apparently benign pheochromocytoma.

Timmers HJ, Brouwers FM, Hermus AR, Sweep FC, Verhofstad AA, Verbeek AL, Pacak K, Lenders JW.

Endocr Relat Cancer. 2008 Dec;15(4):1127-33. Epub 2008 Sep 29.PMID: 18824558 [PubMed - indexed for MEDLINE]Related articles

Comparison of 6-18F-fluorodopamine PET with 123I-metaiodobenzylguanidine and 111in-pentetreotide scintigraphy in localization of nonmetastatic and metastatic pheochromocytoma.

Ilias I, Chen CC, Carrasquillo JA, Whatley M, Ling A, Lazúrová I, Adams KT, Perera S, Pacak K.

J Nucl Med. 2008 Oct;49(10):1613-9. Epub 2008 Sep 15.PMID: 18794260 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment of malignant pheochromocytoma/paraganglioma with cyclophosphamide, vincristine, and dacarbazine: recommendation from a 22-year follow-up of 18 patients.

Huang H, Abraham J, Hung E, Averbuch S, Merino M, Steinberg SM, Pacak K, Fojo T.

Cancer. 2008 Oct 15;113(8):2020-8.PMID: 18780317 [PubMed - indexed for MEDLINE]Related articlesFree article

Update on pediatric pheochromocytoma.

Havekes B, Romijn JA, Eisenhofer G, Adams K, Pacak K.

Pediatr Nephrol. 2009 May;24(5):943-50. Epub 2008 Jun 20. Review.PMID: 18566838 [PubMed - indexed for MEDLINE]Related articles

Current progress and future challenges in the biochemical diagnosis and treatment of pheochromocytomas and paragangliomas.

Eisenhofer G, Siegert G, Kotzerke J, Bornstein SR, Pacak K.

Horm Metab Res. 2008 May;40(5):329-37. Review.PMID: 18491252 [PubMed - indexed for MEDLINE]Related articles

Role of positron emission tomography and bone scintigraphy in the evaluation of bone involvement in metastatic pheochromocytoma and paraganglioma: specific implications for succinate dehydrogenase enzyme subunit B gene mutations.

Zelinka T, Timmers HJ, Kozupa A, Chen CC, Carrasquillo JA, Reynolds JC, Ling A, Eisenhofer G, Lazúrová I, Adams KT, Whatley MA, Widimsky J Jr, Pacak K.

Endocr Relat Cancer. 2008 Mar;15(1):311-23.PMID: 18310297 [PubMed - indexed for MEDLINE]Related articlesFree article

Pheochromocytoma crisis induced by glucocorticoids: a report of four cases and review of the literature.

Rosas AL, Kasperlik-Zaluska AA, Papierska L, Bass BL, Pacak K, Eisenhofer G.

Eur J Endocrinol. 2008 Mar;158(3):423-9. Review.PMID: 18299478 [PubMed - indexed for MEDLINE]Related articlesFree article

Pheochromocytoma.

Havekes B, Pacak K.

Nat Clin Pract Cardiovasc Med. 2008 Feb;5(2):E1. No abstract available. PMID: 18223538 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial localization of human recombinant adenovirus: from evolution to gene therapy.

Alesci S, Abu-Asab M, Perera SM, Tsokos M, Morris JC, Pacak K.

Neuroimmunomodulation. 2007;14(5):221-3. Epub 2008 Jan 25.PMID: 18219224 [PubMed - indexed for MEDLINE]Related articlesFree article

Chromogranin a expression in phaeochromocytomas associated with von Hippel-Lindau syndrome and multiple endocrine neoplasia type 2.

Cleary S, Phillips JK, Huynh TT, Pacak K, Fliedner S, Elkahloun AG, Munson P, Worrell RA, Eisenhofer G.

Horm Metab Res. 2007 Dec;39(12):876-83. Epub 2007 Nov 28.PMID: 18046660 [PubMed - indexed for MEDLINE]Related articles

Usefulness of standardized uptake values for distinguishing adrenal glands with pheochromocytoma from normal adrenal glands by use of 6-18F-fluorodopamine PET.

Timmers HJ, Carrasquillo JA, Whatley M, Eisenhofer G, Chen CC, Ling A, Linehan WM, Pinto PA, Adams KT, Pacak K.

J Nucl Med. 2007 Dec;48(12):1940-4. Epub 2007 Nov 15.PMID: 18006611 [PubMed - indexed for MEDLINE]Related articlesFree article

Preoperative management of the pheochromocytoma patient.

Pacak K.

J Clin Endocrinol Metab. 2007 Nov;92(11):4069-79. Review.PMID: 17989126 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutations associated with succinate dehydrogenase D-related malignant paragangliomas.

Timmers HJ, Pacak K, Bertherat J, Lenders JW, Duet M, Eisenhofer G, Stratakis CA, Niccoli-Sire P, Tran BH, Burnichon N, Gimenez-Roqueplo AP.

Clin Endocrinol (Oxf). 2008 Apr;68(4):561-6. Epub 2007 Oct 31.PMID: 17973943 [PubMed - indexed for MEDLINE]Related articles

Adverse drug reactions in patients with phaeochromocytoma: incidence, prevention and management.

Eisenhofer G, Rivers G, Rosas AL, Quezado Z, Manger WM, Pacak K.

Drug Saf. 2007;30(11):1031-62. Review.PMID: 17973541 [PubMed - indexed for MEDLINE]Related articles