PubMed

Molecular evolution of GBV-B hepatitis virus during acute resolving and persistent infections in experimentally infected tamarins.

Takikawa S, Engle R, Faulk K, Emerson S, Purcell RH, Bukh J.

J Gen Virol. 2009 Nov 11. [Epub ahead of print]PMID: 19906942 [PubMed - as supplied by publisher]Related articles

Potent neutralization of anthrax edema toxin by a humanized monoclonal antibody that competes with calmodulin for edema factor binding.

Chen Z, Moayeri M, Zhao H, Crown D, Leppla SH, Purcell RH.

Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13487-92. Epub 2009 Jul 27.PMID: 19651602 [PubMed - indexed for MEDLINE]Related articles

Genotypic characterization of symptomatic hepatitis E virus (HEV) infections in Egypt.

Blackard JT, Rouster SD, Nady S, Galal G, Marzuuk N, Rafaat MM, Daef E, El Din SS, Purcell RH, Emerson SU, Sherman KE, Shata MT.

J Clin Virol. 2009 Oct;46(2):140-4. Epub 2009 Aug 3.PMID: 19651539 [PubMed - in process]Related articles

The size of the viral inoculum contributes to the outcome of hepatitis B virus infection.

Asabe S, Wieland SF, Chattopadhyay PK, Roederer M, Engle RE, Purcell RH, Chisari FV.

J Virol. 2009 Oct;83(19):9652-62. Epub 2009 Jul 22.PMID: 19625407 [PubMed - indexed for MEDLINE]Related articles

Novel chimpanzee/human monoclonal antibodies that neutralize anthrax lethal factor, and evidence for possible synergy with anti-protective antigen antibody.

Chen Z, Moayeri M, Crown D, Emerson S, Gorshkova I, Schuck P, Leppla SH, Purcell RH.

Infect Immun. 2009 Sep;77(9):3902-8. Epub 2009 Jun 15.PMID: 19528217 [PubMed - indexed for MEDLINE]Related articles

Epidemiology of hepatitis E virus in the United States: results from the Third National Health and Nutrition Examination Survey, 1988-1994.

Kuniholm MH, Purcell RH, McQuillan GM, Engle RE, Wasley A, Nelson KE.

J Infect Dis. 2009 Jul 1;200(1):48-56.PMID: 19473098 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutational analysis of the hepatitis C virus E1 glycoprotein in retroviral pseudoparticles and cell-culture-derived H77/JFH1 chimeric infectious virus particles.

Russell RS, Kawaguchi K, Meunier JC, Takikawa S, Faulk K, Bukh J, Purcell RH, Emerson SU.

J Viral Hepat. 2009 Sep;16(9):621-32. Epub 2009 Mar 11.PMID: 19302336 [PubMed - indexed for MEDLINE]Related articlesFree article

Detection of anthrax toxin by an ultrasensitive immunoassay using europium nanoparticles.

Tang S, Moayeri M, Chen Z, Harma H, Zhao J, Hu H, Purcell RH, Leppla SH, Hewlett IK.

Clin Vaccine Immunol. 2009 Mar;16(3):408-13. Epub 2009 Jan 7.PMID: 19129473 [PubMed - indexed for MEDLINE]Related articlesFree article

Time trend of the prevalence of hepatitis E antibodies among farmers and blood donors: a potential zoonosis in Denmark.

Christensen PB, Engle RE, Hjort C, Homburg KM, Vach W, Georgsen J, Purcell RH.

Clin Infect Dis. 2008 Oct 15;47(8):1026-31.PMID: 18781880 [PubMed - indexed for MEDLINE]Related articles

Apolipoprotein c1 association with hepatitis C virus.

Meunier JC, Russell RS, Engle RE, Faulk KN, Purcell RH, Emerson SU.

J Virol. 2008 Oct;82(19):9647-56. Epub 2008 Jul 30.PMID: 18667498 [PubMed - indexed for MEDLINE]Related articlesFree article

Previously infected chimpanzees are not consistently protected against reinfection or persistent infection after reexposure to the identical hepatitis C virus strain.

Bukh J, Thimme R, Meunier JC, Faulk K, Spangenberg HC, Chang KM, Satterfield W, Chisari FV, Purcell RH.

J Virol. 2008 Aug;82(16):8183-95. Epub 2008 Jun 11.PMID: 18550671 [PubMed - indexed for MEDLINE]Related articlesFree article

Humanized monoclonal antibodies derived from chimpanzee Fabs protect against Japanese encephalitis virus in vitro and in vivo.

Goncalvez AP, Chien CH, Tubthong K, Gorshkova I, Roll C, Donau O, Schuck P, Yoksan S, Wang SD, Purcell RH, Lai CJ.

J Virol. 2008 Jul;82(14):7009-21. Epub 2008 May 14.PMID: 18480437 [PubMed - indexed for MEDLINE]Related articlesFree article

Polyclonal immunoglobulins from a chronic hepatitis C virus patient protect human liver-chimeric mice from infection with a homologous hepatitis C virus strain.

Vanwolleghem T, Bukh J, Meuleman P, Desombere I, Meunier JC, Alter H, Purcell RH, Leroux-Roels G.

Hepatology. 2008 Jun;47(6):1846-55.PMID: 18452146 [PubMed - indexed for MEDLINE]Related articles

Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus.

Russell RS, Meunier JC, Takikawa S, Faulk K, Engle RE, Bukh J, Purcell RH, Emerson SU.

Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4370-5. Epub 2008 Mar 11.PMID: 18334634 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatitis E: an emerging awareness of an old disease.

Purcell RH, Emerson SU.

J Hepatol. 2008 Mar;48(3):494-503. Epub 2008 Jan 2. Review.PMID: 18192058 [PubMed - indexed for MEDLINE]Related articles

Hepatitis E.

Emerson SU, Purcell RH.

Pediatr Infect Dis J. 2007 Dec;26(12):1147-8. Review. No abstract available. PMID: 18043454 [PubMed - indexed for MEDLINE]Related articles

Development of a TaqMan assay for the six major genotypes of hepatitis C virus: comparison with commercial assays.

Engle RE, Russell RS, Purcell RH, Bukh J.

J Med Virol. 2008 Jan;80(1):72-9.PMID: 18041021 [PubMed - indexed for MEDLINE]Related articles

Immunity against the GBV-B hepatitis virus in tamarins can prevent productive infection following rechallenge and is long-lived.

Bukh J, Engle RE, Govindarajan S, Purcell RH.

J Med Virol. 2008 Jan;80(1):87-94.PMID: 18041000 [PubMed - indexed for MEDLINE]Related articles

Mutations within potential glycosylation sites in the capsid protein of hepatitis E virus prevent the formation of infectious virus particles.

Graff J, Zhou YH, Torian U, Nguyen H, St Claire M, Yu C, Purcell RH, Emerson SU.

J Virol. 2008 Feb;82(3):1185-94. Epub 2007 Nov 21.PMID: 18032496 [PubMed - indexed for MEDLINE]Related articlesFree article

Isolation and characterization of broadly neutralizing human monoclonal antibodies to the e1 glycoprotein of hepatitis C virus.

Meunier JC, Russell RS, Goossens V, Priem S, Walter H, Depla E, Union A, Faulk KN, Bukh J, Emerson SU, Purcell RH.

J Virol. 2008 Jan;82(2):966-73. Epub 2007 Oct 31.PMID: 17977972 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of hepatitis E-specific cell-mediated immune response using IFN-gamma ELISPOT assay.

Shata MT, Barrett A, Shire NJ, Abdelwahab SF, Sobhy M, Daef E, El-Kamary SS, Hashem M, Engle RE, Purcell RH, Emerson SU, Strickland GT, Sherman KE.

J Immunol Methods. 2007 Dec 1;328(1-2):152-61. Epub 2007 Sep 19.PMID: 17905301 [PubMed - indexed for MEDLINE]Related articlesFree article

Epitope determinants of a chimpanzee dengue virus type 4 (DENV-4)-neutralizing antibody and protection against DENV-4 challenge in mice and rhesus monkeys by passively transferred humanized antibody.

Lai CJ, Goncalvez AP, Men R, Wernly C, Donau O, Engle RE, Purcell RH.

J Virol. 2007 Dec;81(23):12766-74. Epub 2007 Sep 19.PMID: 17881450 [PubMed - indexed for MEDLINE]Related articlesFree article

Monoclonal antibody-mediated enhancement of dengue virus infection in vitro and in vivo and strategies for prevention.

Goncalvez AP, Engle RE, St Claire M, Purcell RH, Lai CJ.

Proc Natl Acad Sci U S A. 2007 May 29;104(22):9422-7. Epub 2007 May 15.PMID: 17517625 [PubMed - indexed for MEDLINE]Related articlesFree article

In vivo study of the HC-TN strain of hepatitis C virus recovered from a patient with fulminant hepatitis: RNA transcripts of a molecular clone (pHC-TN) are infectious in chimpanzees but not in Huh7.5 cells.

Sakai A, Takikawa S, Thimme R, Meunier JC, Spangenberg HC, Govindarajan S, Farci P, Emerson SU, Chisari FV, Purcell RH, Bukh J.

J Virol. 2007 Jul;81(13):7208-19. Epub 2007 Apr 4.PMID: 17409145 [PubMed - indexed for MEDLINE]Related articlesFree article

Using improved technology for filter paper-based blood collection to survey wild Sika deer for antibodies to hepatitis E virus.

Yu C, Zimmerman C, Stone R, Engle RE, Elkins W, Nardone GA, Emerson SU, Purcell RH.

J Virol Methods. 2007 Jun;142(1-2):143-50. Epub 2007 Mar 2.PMID: 17336401 [PubMed - indexed for MEDLINE]Related articlesFree article

A survey of zoonotic pathogens carried by Norway rats in Baltimore, Maryland, USA.

Easterbrook JD, Kaplan JB, Vanasco NB, Reeves WK, Purcell RH, Kosoy MY, Glass GE, Watson J, Klein SL.

Epidemiol Infect. 2007 Oct;135(7):1192-9. Epub 2007 Jan 15.PMID: 17224086 [PubMed - indexed for MEDLINE]Related articles

Positive reactions on Western blots do not necessarily indicate the epitopes on antigens are continuous.

Zhou YH, Chen Z, Purcell RH, Emerson SU.

Immunol Cell Biol. 2007 Jan;85(1):73-8. Epub 2006 Nov 28.PMID: 17130902 [PubMed - indexed for MEDLINE]Related articles

The half-life of hepatitis B virions.

Murray JM, Purcell RH, Wieland SF.

Hepatology. 2006 Nov;44(5):1117-21.PMID: 17058221 [PubMed - indexed for MEDLINE]Related articles

Quantification of hepatitis B virus genomes and infectivity in human serum samples.

Hsia CC, Purcell RH, Farshid M, Lachenbruch PA, Yu MY.

Transfusion. 2006 Oct;46(10):1829-35.PMID: 17002641 [PubMed - indexed for MEDLINE]Related articles

ORF3 protein of hepatitis E virus is not required for replication, virion assembly, or infection of hepatoma cells in vitro.

Emerson SU, Nguyen H, Torian U, Purcell RH.

J Virol. 2006 Nov;80(21):10457-64. Epub 2006 Aug 23.PMID: 16928762 [PubMed - indexed for MEDLINE]Related articlesFree article

A milestone for hepatitis C virus research: a virus generated in cell culture is fully viable in vivo.

Bukh J, Purcell RH.

Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3500-1. Epub 2006 Feb 27. No abstract available. PMID: 16505349 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional analyses of GB virus B p13 protein: development of a recombinant GB virus B hepatitis virus with a p7 protein.

Takikawa S, Engle RE, Emerson SU, Purcell RH, St Claire M, Bukh J.

Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3345-50. Epub 2006 Feb 21.PMID: 16492760 [PubMed - indexed for MEDLINE]Related articlesFree article

Putative neutralization epitopes and broad cross-genotype neutralization of Hepatitis E virus confirmed by a quantitative cell-culture assay.

Emerson SU, Clemente-Casares P, Moiduddin N, Arankalle VA, Torian U, Purcell RH.

J Gen Virol. 2006 Mar;87(Pt 3):697-704.PMID: 16476993 [PubMed - indexed for MEDLINE]Related articlesFree article

Active surveillance for acute viral hepatitis in rural villages in the Nile Delta.

Meky FA, Stoszek SK, Abdel-Hamid M, Selim S, Abdel-Wahab A, Mikhail N, El-Kafrawy S, El-Daly M, Abdel-Aziz F, Sharaf S, Mohamed MK, Engle RE, Emerson SU, Purcell RH, Fix AD, Strickland GT.

Clin Infect Dis. 2006 Mar 1;42(5):628-33. Epub 2006 Jan 25.PMID: 16447107 [PubMed - indexed for MEDLINE]Related articles

Testing of CpG-optimized protein and DNA vaccines against the hepatitis B virus in chimpanzees for immunogenicity and protection from challenge.

Payette PJ, Ma X, Weeratna RD, McCluskie MJ, Shapiro M, Engle RE, Davis HL, Purcell RH.

Intervirology. 2006;49(3):144-51.PMID: 16428890 [PubMed - indexed for MEDLINE]Related articles

Dynamics of hepatitis B virus clearance in chimpanzees.

Murray JM, Wieland SF, Purcell RH, Chisari FV.

Proc Natl Acad Sci U S A. 2005 Dec 6;102(49):17780-5. Epub 2005 Nov 23.PMID: 16306261 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatitis E antibody seroconversion without disease in highly endemic rural Egyptian communities.

Stoszek SK, Engle RE, Abdel-Hamid M, Mikhail N, Abdel-Aziz F, Medhat A, Fix AD, Emerson SU, Purcell RH, Strickland GT.

Trans R Soc Trop Med Hyg. 2006 Feb;100(2):89-94. Epub 2005 Oct 28.PMID: 16257427 [PubMed - indexed for MEDLINE]Related articles

High prevalence of hepatitis E antibodies in pregnant Egyptian women.

Stoszek SK, Abdel-Hamid M, Saleh DA, El Kafrawy S, Narooz S, Hawash Y, Shebl FM, El Daly M, Said A, Kassem E, Mikhail N, Engle RE, Sayed M, Sharaf S, Fix AD, Emerson SU, Purcell RH, Strickland GT.

Trans R Soc Trop Med Hyg. 2006 Feb;100(2):95-101. Epub 2005 Oct 28.PMID: 16257426 [PubMed - indexed for MEDLINE]Related articles

Human monoclonal antibodies that react with the E2 glycoprotein of hepatitis C virus and possess neutralizing activity.

Schofield DJ, Bartosch B, Shimizu YK, Allander T, Alter HJ, Emerson SU, Cosset FL, Purcell RH.

Hepatology. 2005 Nov;42(5):1055-62.PMID: 16250048 [PubMed - indexed for MEDLINE]Related articles

Thermal stability of hepatitis E virus.

Emerson SU, Arankalle VA, Purcell RH.

J Infect Dis. 2005 Sep 1;192(5):930-3. Epub 2005 Jul 12.PMID: 16088844 [PubMed - indexed for MEDLINE]Related articles

The open reading frame 3 gene of hepatitis E virus contains a cis-reactive element and encodes a protein required for infection of macaques.

Graff J, Nguyen H, Yu C, Elkins WR, St Claire M, Purcell RH, Emerson SU.

J Virol. 2005 Jun;79(11):6680-9.PMID: 15890906 [PubMed - indexed for MEDLINE]Related articlesFree article

A truncated ORF2 protein contains the most immunogenic site on ORF2: antibody responses to non-vaccine sequences following challenge of vaccinated and non-vaccinated macaques with hepatitis E virus.

Zhou YH, Purcell RH, Emerson SU.

Vaccine. 2005 May 2;23(24):3157-65.PMID: 15837215 [PubMed - indexed for MEDLINE]Related articles

Evidence for cross-genotype neutralization of hepatitis C virus pseudo-particles and enhancement of infectivity by apolipoprotein C1.

Meunier JC, Engle RE, Faulk K, Zhao M, Bartosch B, Alter H, Emerson SU, Cosset FL, Purcell RH, Bukh J.

Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4560-5. Epub 2005 Mar 14.PMID: 15767578 [PubMed - indexed for MEDLINE]Related articlesFree article

In vitro and in vivo mutational analysis of the 3'-terminal regions of hepatitis e virus genomes and replicons.

Graff J, Nguyen H, Kasorndorkbua C, Halbur PG, St Claire M, Purcell RH, Emerson SU.

J Virol. 2005 Jan;79(2):1017-26.PMID: 15613330 [PubMed - indexed for MEDLINE]Related articlesFree article

Running like water--the omnipresence of hepatitis E.

Emerson SU, Purcell RH.

N Engl J Med. 2004 Dec 2;351(23):2367-8. No abstract available. PMID: 15575050 [PubMed - indexed for MEDLINE]Related articles

Epitope determinants of a chimpanzee Fab antibody that efficiently cross-neutralizes dengue type 1 and type 2 viruses map to inside and in close proximity to fusion loop of the dengue type 2 virus envelope glycoprotein.

Goncalvez AP, Purcell RH, Lai CJ.

J Virol. 2004 Dec;78(23):12919-28.PMID: 15542644 [PubMed - indexed for MEDLINE]Related articlesFree article

Chimpanzee Fab fragments and a derived humanized immunoglobulin G1 antibody that efficiently cross-neutralize dengue type 1 and type 2 viruses.

Goncalvez AP, Men R, Wernly C, Purcell RH, Lai CJ.

J Virol. 2004 Dec;78(23):12910-8.PMID: 15542643 [PubMed - indexed for MEDLINE]Related articlesFree article

An ELISA for putative neutralizing antibodies to hepatitis E virus detects antibodies to genotypes 1, 2, 3, and 4.

Zhou YH, Purcell RH, Emerson SU.

Vaccine. 2004 Jun 30;22(20):2578-85.PMID: 15193383 [PubMed - indexed for MEDLINE]Related articles

Long-term benefit of interferon alpha therapy of chronic hepatitis D: regression of advanced hepatic fibrosis.

Farci P, Roskams T, Chessa L, Peddis G, Mazzoleni AP, Scioscia R, Serra G, Lai ME, Loy M, Caruso L, Desmet V, Purcell RH, Balestrieri A.

Gastroenterology. 2004 Jun;126(7):1740-9.PMID: 15188169 [PubMed - indexed for MEDLINE]Related articles

Determination and analysis of the complete genomic sequence of avian hepatitis E virus (avian HEV) and attempts to infect rhesus monkeys with avian HEV.

Huang FF, Sun ZF, Emerson SU, Purcell RH, Shivaprasad HL, Pierson FW, Toth TE, Meng XJ.

J Gen Virol. 2004 Jun;85(Pt 6):1609-18.PMID: 15166445 [PubMed - indexed for MEDLINE]Related articlesFree article