PubMed

The values and limits of an in vitro model of Pompe disease: the best laid schemes o' mice an' men...

Takikita S, Myerowitz R, Schreiner C, Baum R, Raben N, Plotz PH.

Autophagy. 2009 Jul;5(5):729-31.PMID: 19571661 [PubMed - indexed for MEDLINE]Related articlesFree article

Murine muscle cell models for Pompe disease and their use in studying therapeutic approaches.

Takikita S, Myerowitz R, Zaal K, Raben N, Plotz PH.

Mol Genet Metab. 2009 Apr;96(4):208-17. Epub 2009 Jan 22.PMID: 19167256 [PubMed - indexed for MEDLINE]Related articlesFree article

Distribution and severity of weakness among patients with polymyositis, dermatomyositis and juvenile dermatomyositis.

Harris-Love MO, Shrader JA, Koziol D, Pahlajani N, Jain M, Smith M, Cintas HL, McGarvey CL, James-Newton L, Pokrovnichka A, Moini B, Cabalar I, Lovell DJ, Wesley R, Plotz PH, Miller FW, Hicks JE, Rider LG.

Rheumatology (Oxford). 2009 Feb;48(2):134-9. Epub 2008 Dec 11.PMID: 19074186 [PubMed - indexed for MEDLINE]Related articles

Role of autophagy in the pathogenesis of Pompe disease.

Raben N, Roberts A, Plotz PH.

Acta Myol. 2007 Jul;26(1):45-8. Review.PMID: 17915569 [PubMed - indexed for MEDLINE]Related articles

Deconstructing Pompe disease by analyzing single muscle fibers: to see a world in a grain of sand...

Raben N, Takikita S, Pittis MG, Bembi B, Marie SK, Roberts A, Page L, Kishnani PS, Schoser BG, Chien YH, Ralston E, Nagaraju K, Plotz PH.

Autophagy. 2007 Nov-Dec;3(6):546-52. Epub 2007 Jun 15.PMID: 17592248 [PubMed - indexed for MEDLINE]Related articlesFree article

Acid alpha-glucosidase deficiency (Pompe disease).

Fukuda T, Roberts A, Plotz PH, Raben N.

Curr Neurol Neurosci Rep. 2007 Jan;7(1):71-7. Review.PMID: 17217857 [PubMed - indexed for MEDLINE]Related articles

Autophagy and mistargeting of therapeutic enzyme in skeletal muscle in Pompe disease.

Fukuda T, Ahearn M, Roberts A, Mattaliano RJ, Zaal K, Ralston E, Plotz PH, Raben N.

Mol Ther. 2006 Dec;14(6):831-9. Epub 2006 Sep 27.PMID: 17008131 [PubMed - indexed for MEDLINE]Related articlesFree article

Autophagy and lysosomes in Pompe disease.

Fukuda T, Roberts A, Ahearn M, Zaal K, Ralston E, Plotz PH, Raben N.

Autophagy. 2006 Oct-Dec;2(4):318-20. Epub 2006 Oct 5.PMID: 16874053 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1, and -DQA1 allelic profiles distinguish European American patients with different myositis autoantibodies.

O'Hanlon TP, Carrick DM, Targoff IN, Arnett FC, Reveille JD, Carrington M, Gao X, Oddis CV, Morel PA, Malley JD, Malley K, Shamim EA, Rider LG, Chanock SJ, Foster CB, Bunch T, Blackshear PJ, Plotz PH, Love LA, Miller FW.

Medicine (Baltimore). 2006 Mar;85(2):111-27.PMID: 16609350 [PubMed - indexed for MEDLINE]Related articles

Dysfunction of endocytic and autophagic pathways in a lysosomal storage disease.

Fukuda T, Ewan L, Bauer M, Mattaliano RJ, Zaal K, Ralston E, Plotz PH, Raben N.

Ann Neurol. 2006 Apr;59(4):700-8.PMID: 16532490 [PubMed - indexed for MEDLINE]Related articles

Endothelial cell activation and neovascularization are prominent in dermatomyositis.

Nagaraju K, Rider LG, Fan C, Chen YW, Mitsak M, Rawat R, Patterson K, Grundtman C, Miller FW, Plotz PH, Hoffman E, Lundberg IE.

J Autoimmune Dis. 2006 Feb 20;3:2.PMID: 16504012 [PubMed]Related articlesFree article

Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1 and -DQA1 allelic profiles and motifs define clinicopathologic groups in caucasians.

O'Hanlon TP, Carrick DM, Arnett FC, Reveille JD, Carrington M, Gao X, Oddis CV, Morel PA, Malley JD, Malley K, Dreyfuss J, Shamim EA, Rider LG, Chanock SJ, Foster CB, Bunch T, Plotz PH, Love LA, Miller FW.

Medicine (Baltimore). 2005 Nov;84(6):338-49.PMID: 16267409 [PubMed - indexed for MEDLINE]Related articles

Seasonal influence on the onset of idiopathic inflammatory myopathies in serologically defined groups.

Sarkar K, Weinberg CR, Oddis CV, Medsger TA Jr, Plotz PH, Reveille JD, Arnett FC, Targoff IN, Genth E, Love LA, Miller FW.

Arthritis Rheum. 2005 Aug;52(8):2433-8.PMID: 16052581 [PubMed - indexed for MEDLINE]Related articlesFree article

Replacing acid alpha-glucosidase in Pompe disease: recombinant and transgenic enzymes are equipotent, but neither completely clears glycogen from type II muscle fibers.

Raben N, Fukuda T, Gilbert AL, de Jong D, Thurberg BL, Mattaliano RJ, Meikle P, Hopwood JJ, Nagashima K, Nagaraju K, Plotz PH.

Mol Ther. 2005 Jan;11(1):48-56.PMID: 15585405 [PubMed - indexed for MEDLINE]Related articles

Myositis: an update on pathogenesis.

Christopher-Stine L, Plotz PH.

Curr Opin Rheumatol. 2004 Nov;16(6):700-6. Review.PMID: 15577607 [PubMed - indexed for MEDLINE]Related articles

Polymyositis: an overdiagnosed entity.

Miller FW, Rider LG, Plotz PH, Rutkove SB, Pestronk A, Wortmann RL, Lundberg IE, Argov Z, Isenberg DA, Lacomis D, Oddis CV.

Neurology. 2004 Jul 27;63(2):402; author reply 403. No abstract available. PMID: 15277657 [PubMed - indexed for MEDLINE]Related articles

Adult inflammatory myopathies.

Christopher-Stine L, Plotz PH.

Best Pract Res Clin Rheumatol. 2004 Jun;18(3):331-44. Review.PMID: 15158744 [PubMed - indexed for MEDLINE]Related articles

Diagnostic criteria for polymyositis and dermatomyositis.

Miller FW, Rider LG, Plotz PH, Isenberg DA, Oddis CV.

Lancet. 2003 Nov 22;362(9397):1762-3; author reply 1763. No abstract available. PMID: 14643132 [PubMed - indexed for MEDLINE]Related articles

Enzyme replacement therapy in the mouse model of Pompe disease.

Raben N, Danon M, Gilbert AL, Dwivedi S, Collins B, Thurberg BL, Mattaliano RJ, Nagaraju K, Plotz PH.

Mol Genet Metab. 2003 Sep-Oct;80(1-2):159-69.PMID: 14567965 [PubMed - indexed for MEDLINE]Related articles

Induction of tolerance to a recombinant human enzyme, acid alpha-glucosidase, in enzyme deficient knockout mice.

Raben N, Nagaraju K, Lee A, Lu N, Rivera Y, Jatkar T, Hopwood JJ, Plotz PH.

Transgenic Res. 2003 Apr;12(2):171-8.PMID: 12739885 [PubMed - indexed for MEDLINE]Related articles

The autoantibody repertoire: searching for order.

Plotz PH.

Nat Rev Immunol. 2003 Jan;3(1):73-8. Review.PMID: 12511877 [PubMed - indexed for MEDLINE]Related articles

Animal models of myositis.

Nagaraju K, Plotz PH.

Rheum Dis Clin North Am. 2002 Nov;28(4):917-33. Review.PMID: 12506778 [PubMed - indexed for MEDLINE]Related articles

Glycogen stored in skeletal but not in cardiac muscle in acid alpha-glucosidase mutant (Pompe) mice is highly resistant to transgene-encoded human enzyme.

Raben N, Jatkar T, Lee A, Lu N, Dwivedi S, Nagaraju K, Plotz PH.

Mol Ther. 2002 Nov;6(5):601-8.PMID: 12409258 [PubMed - indexed for MEDLINE]Related articles

Histidyl-tRNA synthetase and asparaginyl-tRNA synthetase, autoantigens in myositis, activate chemokine receptors on T lymphocytes and immature dendritic cells.

Howard OM, Dong HF, Yang D, Raben N, Nagaraju K, Rosen A, Casciola-Rosen L, Härtlein M, Kron M, Yang D, Yiadom K, Dwivedi S, Plotz PH, Oppenheim JJ.

J Exp Med. 2002 Sep 16;196(6):781-91.PMID: 12235211 [PubMed - indexed for MEDLINE]Related articlesFree article

Correction of the enzymatic and functional deficits in a model of Pompe disease using adeno-associated virus vectors.

Fraites TJ Jr, Schleissing MR, Shanely RA, Walter GA, Cloutier DA, Zolotukhin I, Pauly DF, Raben N, Plotz PH, Powers SK, Kessler PD, Byrne BJ.

Mol Ther. 2002 May;5(5 Pt 1):571-8.PMID: 11991748 [PubMed - indexed for MEDLINE]Related articlesFree article

Hes-1, a known transcriptional repressor, acts as a transcriptional activator for the human acid alpha-glucosidase gene in human fibroblast cells.

Yan B, Raben N, Plotz PH.

Biochem Biophys Res Commun. 2002 Mar 1;291(3):582-7.PMID: 11855828 [PubMed - indexed for MEDLINE]Related articles

Conditional tissue-specific expression of the acid alpha-glucosidase (GAA) gene in the GAA knockout mice: implications for therapy.

Raben N, Lu N, Nagaraju K, Rivera Y, Lee A, Yan B, Byrne B, Meikle PJ, Umapathysivam K, Hopwood JJ, Plotz PH.

Hum Mol Genet. 2001 Sep 15;10(19):2039-47.PMID: 11590121 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification and characterization of a tissue-specific silencer element in the first intron of the human acid maltase gene.

Yan B, Raben N, Lu N, Plotz PH.

Hum Genet. 2001 Aug;109(2):186-90.PMID: 11511924 [PubMed - indexed for MEDLINE]Related articles

Intercellular transfer of the virally derived precursor form of acid alpha-glucosidase corrects the enzyme deficiency in inherited cardioskeletal myopathy Pompe disease.

Pauly DF, Fraites TJ, Toma C, Bayes HS, Huie ML, Hirschhorn R, Plotz PH, Raben N, Kessler PD, Byrne BJ.

Hum Gene Ther. 2001 Mar 20;12(5):527-38.PMID: 11268285 [PubMed - indexed for MEDLINE]Related articles

The DNA mismatch repair enzyme PMS1 is a myositis-specific autoantigen.

Casciola-Rosen LA, Pluta AF, Plotz PH, Cox AE, Morris S, Wigley FM, Petri M, Gelber AC, Rosen A.

Arthritis Rheum. 2001 Feb;44(2):389-96.PMID: 11229471 [PubMed - indexed for MEDLINE]Related articlesFree article

Workshop on inflammatory myopathy Bethesda, 5-6 April 2000.

Plotz PH, Miller F, Hoffman E, Casciola-Rosen L, Rosen A.

Neuromuscul Disord. 2001 Jan;11(1):93-5. No abstract available. PMID: 11166171 [PubMed - indexed for MEDLINE]Related articles

Transcriptional regulation of the human acid alpha-glucosidase gene. Identification of a repressor element and its transcription factors Hes-1 and YY1.

Yan B, Heus J, Lu N, Nichols RC, Raben N, Plotz PH.

J Biol Chem. 2001 Jan 19;276(3):1789-93. Epub 2000 Oct 18.PMID: 11038350 [PubMed - indexed for MEDLINE]Related articlesFree article

Costimulatory markers in muscle of patients with idiopathic inflammatory myopathies and in cultured muscle cells.

Nagaraju K, Raben N, Villalba ML, Danning C, Loeffler LA, Lee E, Tresser N, Abati A, Fetsch P, Plotz PH.

Clin Immunol. 1999 Aug;92(2):161-9.PMID: 10444360 [PubMed - indexed for MEDLINE]Related articles

Inclusion body myositis long after dermatomyositis: a report of two cases.

McCoy AL, Bubb MR, Plotz PH, Davis JC.

Clin Exp Rheumatol. 1999 Mar-Apr;17(2):235-9.PMID: 10342053 [PubMed - indexed for MEDLINE]Related articles

Novel mutations in African American patients with glycogen storage disease Type II. Mutations in brief no. 209. Online.

Raben N, Lee E, Lee L, Hirschhorn R, Plotz PH.

Hum Mutat. 1999;13(1):83-4.PMID: 10189220 [PubMed - indexed for MEDLINE]Related articles

A pilot study: use of fludarabine for refractory dermatomyositis and polymyositis, and examination of endpoint measures.

Adams EM, Pucino F, Yarboro C, Hicks JE, Thornton B, McGarvey C, Sonies BC, Bartlett ML, Villalba ML, Fleisher T, Plotz PH.

J Rheumatol. 1999 Feb;26(2):352-60.PMID: 9972969 [PubMed - indexed for MEDLINE]Related articles

The African origin of the common mutation in African American patients with glycogen-storage disease type II.

Becker JA, Vlach J, Raben N, Nagaraju K, Adams EM, Hermans MM, Reuser AJ, Brooks SS, Tifft CJ, Hirschhorn R, Huie ML, Nicolino M, Plotz PH.

Am J Hum Genet. 1998 Apr;62(4):991-4. No abstract available. PMID: 9529346 [PubMed - indexed for MEDLINE]Related articlesFree article

Familial autoimmunity in pedigrees of idiopathic inflammatory myopathy patients suggests common genetic risk factors for many autoimmune diseases.

Ginn LR, Lin JP, Plotz PH, Bale SJ, Wilder RL, Mbauya A, Miller FW.

Arthritis Rheum. 1998 Mar;41(3):400-5.PMID: 9506566 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment of refractory myositis: a randomized crossover study of two new cytotoxic regimens.

Villalba L, Hicks JE, Adams EM, Sherman JB, Gourley MF, Leff RL, Thornton BC, Burgess SH, Plotz PH, Miller FW.

Arthritis Rheum. 1998 Mar;41(3):392-9.PMID: 9506565 [PubMed - indexed for MEDLINE]Related articlesFree article

Retroviral transfer of acid alpha-glucosidase cDNA to enzyme-deficient myoblasts results in phenotypic spread of the genotypic correction by both secretion and fusion.

Zaretsky JZ, Candotti F, Boerkoel C, Adams EM, Yewdell JW, Blaese RM, Plotz PH.

Hum Gene Ther. 1997 Sep 1;8(13):1555-63. Erratum in: Hum Gene Ther 1998 Apr 10;9(6):930. PMID: 9322088 [PubMed - indexed for MEDLINE]Related articles

The predominance of beta (CC) chemokine transcripts in idiopathic inflammatory muscle diseases.

Adams EM, Kirkley J, Eidelman G, Dohlman J, Plotz PH.

Proc Assoc Am Physicians. 1997 May;109(3):275-85.PMID: 9154644 [PubMed - indexed for MEDLINE]Related articles

Glycogenosis type II: a juvenile-specific mutation with an unusual splicing pattern and a shared mutation in African Americans.

Adams EM, Becker JA, Griffith L, Segal A, Plotz PH, Raben N.

Hum Mutat. 1997;10(2):128-34.PMID: 9259196 [PubMed - indexed for MEDLINE]Related articles

Deconstructing disease: an anatomy of illness in the age of molecular biology.

Plotz PH.

Perspect Biol Med. 1997 Winter;40(2):160-4. No abstract available. PMID: 9058949 [PubMed - indexed for MEDLINE]Related articles

Abnormal numbers of cytokine producing cells in patients with polymyositis and dermatomyositis.

Hagiwara E, Adams EM, Plotz PH, Klinman DM.

Clin Exp Rheumatol. 1996 Sep-Oct;14(5):485-91.PMID: 8913649 [PubMed - indexed for MEDLINE]Related articles

Assignment of two human autoantigen genes-isoleucyl-tRNA synthetase locates to 9q21 and lysyl-tRNA synthetase locates to 16q23-q24.

Nichols RC, Blinder J, Pai SI, Ge Q, Targoff IN, Plotz PH, Liu P.

Genomics. 1996 Aug 15;36(1):210-3. No abstract available. PMID: 8812440 [PubMed - indexed for MEDLINE]Related articles

A model of mRNA splicing in adult lysosomal storage disease (glycogenosis type II).

Raben N, Nichols RC, Martiniuk F, Plotz PH.

Hum Mol Genet. 1996 Jul;5(7):995-1000.PMID: 8817337 [PubMed - indexed for MEDLINE]Related articlesFree article

Glycogenosis type VII (Tarui disease) in a Swedish family: two novel mutations in muscle phosphofructokinase gene (PFK-M) resulting in intron retentions.

Nichols RC, Rudolphi O, Ek B, Exelbert R, Plotz PH, Raben N.

Am J Hum Genet. 1996 Jul;59(1):59-65.PMID: 8659544 [PubMed - indexed for MEDLINE]Related articlesFree article

Failure of low-dose intravenous immunoglobulin therapy to suppress disease activity in patients with treatment-refractory rheumatoid arthritis.

Kanik KS, Yarboro CH, Naparstek Y, Plotz PH, Wilder RL.

Arthritis Rheum. 1996 Jun;39(6):1027-9.PMID: 8651966 [PubMed - indexed for MEDLINE]Related articles

Myositis following treatment with high dose interleukin-2 for malignancy.

Finger DR, Plotz PH, Heywood G.

J Rheumatol. 1995 Nov;22(11):2188. No abstract available. PMID: 8596171 [PubMed - indexed for MEDLINE]Related articles

Localization of two human autoantigen genes by PCR screening and in situ hybridization--glycyl-tRNA synthetase locates to 7p15 and alanyl-tRNA synthetase locates to 16q22.

Nichols RC, Pai SI, Ge Q, Targoff IN, Plotz PH, Liu P.

Genomics. 1995 Nov 1;30(1):131-2. No abstract available. PMID: 8595897 [PubMed - indexed for MEDLINE]Related articles