PubMed

AUF1 isoform-specific regulation of anti-inflammatory IL10 expression in monocytes.

Sarkar S, Sinsimer KS, Foster RL, Brewer G, Pestka S.

J Interferon Cytokine Res. 2008 Nov;28(11):679-91.PMID: 18844578 [PubMed - indexed for MEDLINE]Related articles

Interferon protects mice against inhalation anthrax.

Walberg K, Baron S, Poast J, Schwartz B, Izotova L, Pestka S, Peterson JW.

J Interferon Cytokine Res. 2008 Oct;28(10):597-601.PMID: 18778201 [PubMed - indexed for MEDLINE]Related articles

Chaperone Hsp27, a novel subunit of AUF1 protein complexes, functions in AU-rich element-mediated mRNA decay.

Sinsimer KS, Gratacós FM, Knapinska AM, Lu J, Krause CD, Wierzbowski AV, Maher LR, Scrudato S, Rivera YM, Gupta S, Turrin DK, De La Cruz MP, Pestka S, Brewer G.

Mol Cell Biol. 2008 Sep;28(17):5223-37. Epub 2008 Jun 23.PMID: 18573886 [PubMed - indexed for MEDLINE]Related articlesFree article

Site-specific phosphorylation of raf in cells containing oncogenic ras-p21 is likely mediated by jun-N-terminal kinase.

Adler V, Bowne W, Michl J, Sookraj KA, Ikram K, Pestka S, Izotova L, Zenilman M, Friedman FK, Qu Y, Pincus MR.

Ann Clin Lab Sci. 2008 Winter;38(1):47-56.PMID: 18316782 [PubMed - indexed for MEDLINE]Related articles

Purification and cloning of interferon alpha.

Pestka S.

Curr Top Microbiol Immunol. 2007;316:23-37. Review.PMID: 17969442 [PubMed - indexed for MEDLINE]Related articles

Historical developments in the research of interferon receptors.

Krause CD, Pestka S.

Cytokine Growth Factor Rev. 2007 Oct-Dec;18(5-6):473-82. Epub 2007 Aug 10. Review.PMID: 17693124 [PubMed - indexed for MEDLINE]Related articles

The dual-specificity kinases, TOPK and DYRK1A, are critical for oocyte maturation induced by wild-type--but not by oncogenic--ras-p21 protein.

Qu Y, Adler V, Izotova L, Pestka S, Bowne W, Michl J, Boutjdir M, Friedman FK, Pincus MR.

Front Biosci. 2007 Sep 1;12:5089-97.PMID: 17569632 [PubMed - indexed for MEDLINE]Related articles

The interferons: 50 years after their discovery, there is much more to learn.

Pestka S.

J Biol Chem. 2007 Jul 13;282(28):20047-51. Epub 2007 May 14. Review.PMID: 17502369 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein arginine methyltransferases: evolution and assessment of their pharmacological and therapeutic potential.

Krause CD, Yang ZH, Kim YS, Lee JH, Cook JR, Pestka S.

Pharmacol Ther. 2007 Jan;113(1):50-87. Epub 2006 Sep 26. Review.PMID: 17005254 [PubMed - indexed for MEDLINE]Related articles

The antineoplastic agent bryostatin-1 differentially regulates IFN-gamma receptor subunits in monocytic cells: transcriptional and posttranscriptional control of IFN-gamma R2.

Garcia CS, Curiel RE, Mwatibo JM, Pestka S, Li H, Espinoza-Delgado I.

J Immunol. 2006 Aug 15;177(4):2707-16.PMID: 16888033 [PubMed - indexed for MEDLINE]Related articlesFree article

Two dual specificity kinases are preferentially induced by wild-type rather than by oncogenic RAS-P21 in Xenopus oocytes.

Qu Y, Adler V, Chu T, Platica O, Michl J, Pestka S, Izotova L, Boutjdir M, Pincus MR.

Front Biosci. 2006 Sep 1;11:2420-7.PMID: 16720323 [PubMed - indexed for MEDLINE]Related articles

FBXO11/PRMT9, a new protein arginine methyltransferase, symmetrically dimethylates arginine residues.

Cook JR, Lee JH, Yang ZH, Krause CD, Herth N, Hoffmann R, Pestka S.

Biochem Biophys Res Commun. 2006 Apr 7;342(2):472-81. Epub 2006 Feb 8.PMID: 16487488 [PubMed - indexed for MEDLINE]Related articles

Modulation of the activation of Stat1 by the interferon-gamma receptor complex.

Krause CD, He W, Kotenko S, Pestka S.

Cell Res. 2006 Jan;16(1):113-23.PMID: 16467883 [PubMed - indexed for MEDLINE]Related articlesFree article

Preassembly and ligand-induced restructuring of the chains of the IFN-gamma receptor complex: the roles of Jak kinases, Stat1 and the receptor chains.

Krause CD, Lavnikova N, Xie J, Mei E, Mirochnitchenko OV, Jia Y, Hochstrasser RM, Pestka S.

Cell Res. 2006 Jan;16(1):55-69.PMID: 16467876 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevated expression of ISG15 in tumor cells interferes with the ubiquitin/26S proteasome pathway.

Desai SD, Haas AL, Wood LM, Tsai YC, Pestka S, Rubin EH, Saleem A, Nur-E-Kamal A, Liu LF.

Cancer Res. 2006 Jan 15;66(2):921-8.PMID: 16424026 [PubMed - indexed for MEDLINE]Related articlesFree article

Interactions among the components of the interleukin-10 receptor complex.

Krause CD, Mei E, Mirochnitchenko O, Lavnikova N, Xie J, Jia Y, Hochstrasser RM, Pestka S.

Biochem Biophys Res Commun. 2006 Feb 10;340(2):377-85. Epub 2005 Dec 13.PMID: 16364239 [PubMed - indexed for MEDLINE]Related articles

Functional interactions of Raf and MEK with Jun-N-terminal kinase (JNK) result in a positive feedback loop on the oncogenic Ras signaling pathway.

Adler V, Qu Y, Smith SJ, Izotova L, Pestka S, Kung HF, Lin M, Friedman FK, Chie L, Chung D, Boutjdir M, Pincus MR.

Biochemistry. 2005 Aug 16;44(32):10784-95.PMID: 16086581 [PubMed - indexed for MEDLINE]Related articles

Evolution of the Class 2 cytokines and receptors, and discovery of new friends and relatives.

Krause CD, Pestka S.

Pharmacol Ther. 2005 Jun;106(3):299-346. Epub 2005 Apr 14. Review.PMID: 15922016 [PubMed - indexed for MEDLINE]Related articles

Design and construction of a phosphorylatable chimeric monoclonal antibody with a highly stable phosphate.

Wu W, Kerrigan JE, Yadav P, Schwartz B, Izotova L, Lavoie TB, Pestka S.

Oncol Res. 2004;14(11-12):541-58.PMID: 15666996 [PubMed - indexed for MEDLINE]Related articles

Interferons, interferon-like cytokines, and their receptors.

Pestka S, Krause CD, Walter MR.

Immunol Rev. 2004 Dec;202:8-32. Review.PMID: 15546383 [PubMed - indexed for MEDLINE]Related articles

PRMT7, a new protein arginine methyltransferase that synthesizes symmetric dimethylarginine.

Lee JH, Cook JR, Yang ZH, Mirochnitchenko O, Gunderson SI, Felix AM, Herth N, Hoffmann R, Pestka S.

J Biol Chem. 2005 Feb 4;280(5):3656-64. Epub 2004 Oct 19.PMID: 15494416 [PubMed - indexed for MEDLINE]Related articlesFree article

Spliceosome Sm proteins D1, D3, and B/B' are asymmetrically dimethylated at arginine residues in the nucleus.

Miranda TB, Khusial P, Cook JR, Lee JH, Gunderson SI, Pestka S, Zieve GW, Clarke S.

Biochem Biophys Res Commun. 2004 Oct 15;323(2):382-7.PMID: 15369763 [PubMed - indexed for MEDLINE]Related articles

The IL-10R2 binding hot spot on IL-22 is located on the N-terminal helix and is dependent on N-linked glycosylation.

Logsdon NJ, Jones BC, Allman JC, Izotova L, Schwartz B, Pestka S, Walter MR.

J Mol Biol. 2004 Sep 10;342(2):503-14.PMID: 15327950 [PubMed - indexed for MEDLINE]Related articles

Interleukin-10 and related cytokines and receptors.

Pestka S, Krause CD, Sarkar D, Walter MR, Shi Y, Fisher PB.

Annu Rev Immunol. 2004;22:929-79. Review.PMID: 15032600 [PubMed - indexed for MEDLINE]Related articles

Expression analysis and genomic characterization of human melanoma differentiation associated gene-5, mda-5: a novel type I interferon-responsive apoptosis-inducing gene.

Kang DC, Gopalkrishnan RV, Lin L, Randolph A, Valerie K, Pestka S, Fisher PB.

Oncogene. 2004 Mar 4;23(9):1789-800.PMID: 14676839 [PubMed - indexed for MEDLINE]Related articles

Increased interleukin-10 mRNA stability in melanoma cells is associated with decreased levels of A + U-rich element binding factor AUF1.

Brewer G, Saccani S, Sarkar S, Lewis A, Pestka S.

J Interferon Cytokine Res. 2003 Oct;23(10):553-64.PMID: 14585195 [PubMed - indexed for MEDLINE]Related articles

A dance between interferon-alpha/beta and p53 demonstrates collaborations in tumor suppression and antiviral activities.

Pestka S.

Cancer Cell. 2003 Aug;4(2):85-7.PMID: 12957282 [PubMed - indexed for MEDLINE]Related articles

A protein methyl transferase, PRMT5, selectively blocks oncogenic ras-p21 mitogenic signal transduction.

Chie L, Cook JR, Chung D, Hoffmann R, Yang Z, Kim Y, Pestka S, Pincus MR.

Ann Clin Lab Sci. 2003 Spring;33(2):200-7.PMID: 12817625 [PubMed - indexed for MEDLINE]Related articles

Mda-7/IL-24 induces apoptosis of diverse cancer cell lines through JAK/STAT-independent pathways.

Sauane M, Gopalkrishnan RV, Lebedeva I, Mei MX, Sarkar D, Su ZZ, Kang DC, Dent P, Pestka S, Fisher PB.

J Cell Physiol. 2003 Aug;196(2):334-45.PMID: 12811827 [PubMed - indexed for MEDLINE]Related articles

MDA-7/IL-24: novel cancer growth suppressing and apoptosis inducing cytokine.

Sauane M, Gopalkrishnan RV, Sarkar D, Su ZZ, Lebedeva IV, Dent P, Pestka S, Fisher PB.

Cytokine Growth Factor Rev. 2003 Feb;14(1):35-51. Review.PMID: 12485618 [PubMed - indexed for MEDLINE]Related articles

Seeing the light: preassembly and ligand-induced changes of the interferon gamma receptor complex in cells.

Krause CD, Mei E, Xie J, Jia Y, Bopp MA, Hochstrasser RM, Pestka S.

Mol Cell Proteomics. 2002 Oct;1(10):805-15.PMID: 12438563 [PubMed - indexed for MEDLINE]Related articlesFree article

Site-specific 32P-labeling of cytokines, monoclonal antibodies, and other protein substrates for quantitative assays and therapeutic application.

Clark WA, Izotova L, Philipova D, Wu W, Lin L, Pestka S.

Biotechniques. 2002 Oct;Suppl:76-8, 80-7. Review.PMID: 12395930 [PubMed - indexed for MEDLINE]Related articles

Negative regulation of transcription by the type II arginine methyltransferase PRMT5.

Fabbrizio E, El Messaoudi S, Polanowska J, Paul C, Cook JR, Lee JH, Negre V, Rousset M, Pestka S, Le Cam A, Sardet C.

EMBO Rep. 2002 Jul;3(7):641-5.PMID: 12101096 [PubMed - indexed for MEDLINE]Related articlesFree article

Interferon-gamma receptor 2 expression as the deciding factor in human T, B, and myeloid cell proliferation or death.

Bernabei P, Coccia EM, Rigamonti L, Bosticardo M, Forni G, Pestka S, Krause CD, Battistini A, Novelli F.

J Leukoc Biol. 2001 Dec;70(6):950-60.PMID: 11739558 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential IL-10R1 expression plays a critical role in IL-10-mediated immune regulation.

Ding Y, Qin L, Zamarin D, Kotenko SV, Pestka S, Moore KW, Bromberg JS.

J Immunol. 2001 Dec 15;167(12):6884-92.PMID: 11739506 [PubMed - indexed for MEDLINE]Related articlesFree article

Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties.

Huang EY, Madireddi MT, Gopalkrishnan RV, Leszczyniecka M, Su Z, Lebedeva IV, Kang D, Jiang H, Lin JJ, Alexandre D, Chen Y, Vozhilla N, Mei MX, Christiansen KA, Sivo F, Goldstein NI, Mhashilkar AB, Chada S, Huberman E, Pestka S, Fisher PB.

Oncogene. 2001 Oct 25;20(48):7051-63.PMID: 11704829 [PubMed - indexed for MEDLINE]Related articlesFree article

hTid-1, a human DnaJ protein, modulates the interferon signaling pathway.

Sarkar S, Pollack BP, Lin KT, Kotenko SV, Cook JR, Lewis A, Pestka S.

J Biol Chem. 2001 Dec 28;276(52):49034-42. Epub 2001 Oct 25.PMID: 11679576 [PubMed - indexed for MEDLINE]Related articlesFree article

PRMT5 (Janus kinase-binding protein 1) catalyzes the formation of symmetric dimethylarginine residues in proteins.

Branscombe TL, Frankel A, Lee JH, Cook JR, Yang Z, Pestka S, Clarke S.

J Biol Chem. 2001 Aug 31;276(35):32971-6. Epub 2001 Jun 18.PMID: 11413150 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification, cloning, and characterization of a novel soluble receptor that binds IL-22 and neutralizes its activity.

Kotenko SV, Izotova LS, Mirochnitchenko OV, Esterova E, Dickensheets H, Donnelly RP, Pestka S.

J Immunol. 2001 Jun 15;166(12):7096-103.PMID: 11390454 [PubMed - indexed for MEDLINE]Related articlesFree article

Cloning and characterization of human ubiquitin-processing protease-43 from terminally differentiated human melanoma cells using a rapid subtraction hybridization protocol RaSH.

Kang D, Jiang H, Wu Q, Pestka S, Fisher PB.

Gene. 2001 Apr 18;267(2):233-42.PMID: 11313150 [PubMed - indexed for MEDLINE]Related articles

Cloning, expression and initial characterization of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10).

Gallagher G, Dickensheets H, Eskdale J, Izotova LS, Mirochnitchenko OV, Peat JD, Vazquez N, Pestka S, Donnelly RP, Kotenko SV.

Genes Immun. 2000 Oct;1(7):442-50.PMID: 11196675 [PubMed - indexed for MEDLINE]Related articlesFree article

The human interferon alpha species and receptors.

Pestka S.

Biopolymers. 2000;55(4):254-87. Review.PMID: 11169919 [PubMed - indexed for MEDLINE]Related articles

Use of phosphorylation site tags in proteins.

Pestka S, Lin L, Wu W, Izotova L.

Methods Enzymol. 2000;327:594-613. No abstract available. PMID: 11045011 [PubMed - indexed for MEDLINE]Related articles

Identification of the functional interleukin-22 (IL-22) receptor complex: the IL-10R2 chain (IL-10Rbeta ) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, IL-TIF) receptor complexes.

Kotenko SV, Izotova LS, Mirochnitchenko OV, Esterova E, Dickensheets H, Donnelly RP, Pestka S.

J Biol Chem. 2001 Jan 26;276(4):2725-32. Epub 2000 Oct 16.PMID: 11035029 [PubMed - indexed for MEDLINE]Related articlesFree article

Hsl7p, the yeast homologue of human JBP1, is a protein methyltransferase.

Lee JH, Cook JR, Pollack BP, Kinzy TG, Norris D, Pestka S.

Biochem Biophys Res Commun. 2000 Jul 21;274(1):105-11.PMID: 10903903 [PubMed - indexed for MEDLINE]Related articles

Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes.

Kotenko SV, Pestka S.

Oncogene. 2000 May 15;19(21):2557-65. Review.PMID: 10851054 [PubMed - indexed for MEDLINE]Related articlesFree article

Review of recent developments in the molecular characterization of recombinant alfa interferons on the 40th anniversary of the discovery of interferon.

Walter MR, Bordens R, Nagabhushan TL, Williams BR, Herberman RB, Dinarello CA, Borden EC, Trotta PP, Pestka S, Pfeffer LM.

Cancer Biother Radiopharm. 1998 Jun;13(3):143-54. Review.PMID: 10850350 [PubMed - indexed for MEDLINE]Related articles

Signaling by covalent heterodimers of interferon-gamma. Evidence for one-sided signaling in the active tetrameric receptor complex.

Krause CD, Lunn CA, Izotova LS, Mirochnitchenko O, Kotenko SV, Lundell DJ, Narula SK, Pestka S.

J Biol Chem. 2000 Jul 28;275(30):22995-3004.PMID: 10811814 [PubMed - indexed for MEDLINE]Related articlesFree article

Ligand-independent down-regulation of IFN-gamma receptor 1 following TCR engagement.

Skrenta H, Yang Y, Pestka S, Fathman CG.

J Immunol. 2000 Apr 1;164(7):3506-11.PMID: 10725704 [PubMed - indexed for MEDLINE]Related articlesFree article

Human cytomegalovirus harbors its own unique IL-10 homolog (cmvIL-10).

Kotenko SV, Saccani S, Izotova LS, Mirochnitchenko OV, Pestka S.

Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1695-700.PMID: 10677520 [PubMed - indexed for MEDLINE]Related articlesFree article