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    Results: 1 to 50 of 114

    1.

    NPM1 mutations in therapy-related acute myeloid leukemia with uncharacteristic features.

    Andersen MT, Andersen MK, Christiansen DH, Pedersen-Bjergaard J.

    Leukemia. 2008 May;22(5):951-5. Epub 2008 Feb 14.PMID: 18273044 [PubMed - indexed for MEDLINE]Related articles

    2.

    Genetics of therapy-related myelodysplasia and acute myeloid leukemia.

    Pedersen-Bjergaard J, Andersen MK, Andersen MT, Christiansen DH.

    Leukemia. 2008 Feb;22(2):240-8. Epub 2008 Jan 17. Review.PMID: 18200041 [PubMed - indexed for MEDLINE]Related articles

    3.

    Genetic pathways in the pathogenesis of therapy-related myelodysplasia and acute myeloid leukemia.

    Pedersen-Bjergaard J, Andersen MT, Andersen MK.

    Hematology Am Soc Hematol Educ Program. 2007:392-7. Review.PMID: 18024656 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Mutations of the PTPN11 gene in therapy-related MDS and AML with rare balanced chromosome translocations.

    Christiansen DH, Desta F, Andersen MK, Pedersen-Bjergaard J.

    Genes Chromosomes Cancer. 2007 Jun;46(6):517-21.PMID: 17330262 [PubMed - indexed for MEDLINE]Related articles

    5.

    Alternative genetic pathways and cooperating genetic abnormalities in the pathogenesis of therapy-related myelodysplasia and acute myeloid leukemia.

    Pedersen-Bjergaard J, Christiansen DH, Desta F, Andersen MK.

    Leukemia. 2006 Nov;20(11):1943-9. Epub 2006 Sep 21. Review.PMID: 16990778 [PubMed - indexed for MEDLINE]Related articles

    6.

    Activating mutations of JAK2V617F are uncommon in t-MDS and t-AML and are only observed in atypic cases.

    Desta F, Christiansen DH, Andersen MK, Pedersen-Bjergaard J.

    Leukemia. 2006 Mar;20(3):547-8. No abstract available. PMID: 16424876 [PubMed - indexed for MEDLINE]Related articles

    7.

    Mutations of genes in the receptor tyrosine kinase (RTK)/RAS-BRAF signal transduction pathway in therapy-related myelodysplasia and acute myeloid leukemia.

    Christiansen DH, Andersen MK, Desta F, Pedersen-Bjergaard J.

    Leukemia. 2005 Dec;19(12):2232-40.PMID: 16281072 [PubMed - indexed for MEDLINE]Related articles

    8.

    Insights into leukemogenesis from therapy-related leukemia.

    Pedersen-Bjergaard J.

    N Engl J Med. 2005 Apr 14;352(15):1591-4. No abstract available. PMID: 15829541 [PubMed - indexed for MEDLINE]Related articles

    9.

    Centromeric breakage and highly rearranged chromosome derivatives associated with mutations of TP53 are common in therapy-related MDS and AML after therapy with alkylating agents: an M-FISH study.

    Andersen MK, Christiansen DH, Pedersen-Bjergaard J.

    Genes Chromosomes Cancer. 2005 Apr;42(4):358-71.PMID: 15645489 [PubMed - indexed for MEDLINE]Related articles

    10.

    Amplification or duplication of chromosome band 21q22 with multiple copies of the AML1 gene and mutation of the TP53 gene in therapy-related MDS and AML.

    Andersen MK, Christiansen DH, Pedersen-Bjergaard J.

    Leukemia. 2005 Feb;19(2):197-200.PMID: 15618958 [PubMed - indexed for MEDLINE]Related articles

    11.

    Mutations of AML1 are common in therapy-related myelodysplasia following therapy with alkylating agents and are significantly associated with deletion or loss of chromosome arm 7q and with subsequent leukemic transformation.

    Christiansen DH, Andersen MK, Pedersen-Bjergaard J.

    Blood. 2004 Sep 1;104(5):1474-81. Epub 2004 May 13.PMID: 15142876 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Methylation of p15INK4B is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia.

    Christiansen DH, Andersen MK, Pedersen-Bjergaard J.

    Leukemia. 2003 Sep;17(9):1813-9.PMID: 12970781 [PubMed - indexed for MEDLINE]Related articles

    13.

    Causality of myelodysplasia and acute myeloid leukemia and their genetic abnormalities.

    Pedersen-Bjergaard J, Christiansen DH, Andersen MK, Skovby F.

    Leukemia. 2002 Nov;16(11):2177-84. Review.PMID: 12399959 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Therapy-related MDS and AML in acute promyelocytic leukemia.

    Andersen MK, Pedersen-Bjergaard J.

    Blood. 2002 Sep 1;100(5):1928-9; author reply 1929. No abstract available. PMID: 12211197 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Clonal Ph-negative hematopoiesis in CML after therapy with imatinib mesylate is frequently characterized by trisomy 8.

    Andersen MK, Pedersen-Bjergaard J, Kjeldsen L, Dufva IH, Brøndum-Nielsen K.

    Leukemia. 2002 Jul;16(7):1390-3. No abstract available. PMID: 12094265 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Balanced chromosome abnormalities inv(16) and t(15;17) in therapy-related myelodysplastic syndromes and acute leukemia: report from an international workshop.

    Andersen MK, Larson RA, Mauritzson N, Schnittger S, Jhanwar SC, Pedersen-Bjergaard J.

    Genes Chromosomes Cancer. 2002 Apr;33(4):395-400.PMID: 11921273 [PubMed - indexed for MEDLINE]Related articles

    17.

    Genetic pathways in therapy-related myelodysplasia and acute myeloid leukemia.

    Pedersen-Bjergaard J, Andersen MK, Christiansen DH, Nerlov C.

    Blood. 2002 Mar 15;99(6):1909-12.PMID: 11877259 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Internal tandem duplications of the FLT3 and MLL genes are mainly observed in atypical cases of therapy-related acute myeloid leukemia with a normal karyotype and are unrelated to type of previous therapy.

    Christiansen DH, Pedersen-Bjergaard J.

    Leukemia. 2001 Dec;15(12):1848-51.PMID: 11753604 [PubMed - indexed for MEDLINE]Related articles

    19.

    Therapy-related acute lymphoblastic leukaemia with MLL rearrangements following DNA topoisomerase II inhibitors, an increasing problem: report on two new cases and review of the literature since 1992.

    Andersen MK, Christiansen DH, Jensen BA, Ernst P, Hauge G, Pedersen-Bjergaard J.

    Br J Haematol. 2001 Sep;114(3):539-43. Review.PMID: 11552977 [PubMed - indexed for MEDLINE]Related articles

    20.

    Duplication or amplification of chromosome band 11q23, including the unrearranged MLL gene, is a recurrent abnormality in therapy-related MDS and AML, and is closely related to mutation of the TP53 gene and to previous therapy with alkylating agents.

    Andersen MK, Christiansen DH, Kirchhoff M, Pedersen-Bjergaard J.

    Genes Chromosomes Cancer. 2001 May;31(1):33-41.PMID: 11284033 [PubMed - indexed for MEDLINE]Related articles

    21.

    Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor prognosis.

    Christiansen DH, Andersen MK, Pedersen-Bjergaard J.

    J Clin Oncol. 2001 Mar 1;19(5):1405-13.PMID: 11230485 [PubMed - indexed for MEDLINE]Related articles

    22.

    Molecular cytogenetics in cancer.

    Pedersen-Bjergaard J.

    Lancet. 2001 Feb 17;357(9255):491-2. No abstract available. PMID: 11229662 [PubMed - indexed for MEDLINE]Related articles

    23.

    Cytogenetics of myelodysplasia and acute myeloid leukaemia in aircrew and people treated with radiotherapy.

    Gundestrup M, Klarskov Andersen M, Sveinbjornsdottir E, Rafnsson V, Storm HH, Pedersen-Bjergaard J.

    Lancet. 2000 Dec 23-30;356(9248):2158.PMID: 11191547 [PubMed - indexed for MEDLINE]Related articles

    24.

    Therapy-related acute myeloid leukemia and myelodysplasia after high-dose chemotherapy and autologous stem cell transplantation.

    Pedersen-Bjergaard J, Andersen MK, Christiansen DH.

    Blood. 2000 Jun 1;95(11):3273-9. Review. Erratum in: Blood 2000 Sep 1;96(5):1680. PMID: 10828005 [PubMed - indexed for MEDLINE]Related articlesFree article

    25.

    Increased frequency of dicentric chromosomes in therapy-related MDS and AML compared to de novo disease is significantly related to previous treatment with alkylating agents and suggests a specific susceptibility to chromosome breakage at the centromere.

    Andersen MK, Pedersen-Bjergaard J.

    Leukemia. 2000 Jan;14(1):105-11.PMID: 10637484 [PubMed - indexed for MEDLINE]Related articles

    26.

    Cytogenetically unrelated clones in therapy-related myelodysplasia and acute myeloid leukemia: experience from the Copenhagen series updated to 180 consecutive cases.

    Pedersen-Bjergaard J, Timshel S, Andersen MK, Andersen AS, Philip P.

    Genes Chromosomes Cancer. 1998 Dec;23(4):337-49.PMID: 9824207 [PubMed - indexed for MEDLINE]Related articles

    27.

    BEAM+autologous stem cell transplantation in malignant lymphoma: 100 consecutive transplants in a single centre. Efficacy, toxicity and engraftment in relation to stem-cell source and previous treatment.

    Geisler CH, Hansen MM, Andersen NS, Brown P, Christensen LD, Dickmeiss E, Ersbøll J, Myhre J, Hansen M, Juhl BR, Mortensen BT, Pedersen-Bjergaard J.

    Eur J Haematol. 1998 Sep;61(3):173-82.PMID: 9753413 [PubMed - indexed for MEDLINE]Related articles

    28.

    Chromosomal abnormalities in secondary MDS and AML. Relationship to drugs and radiation with specific emphasis on the balanced rearrangements.

    Andersen MK, Johansson B, Larsen SO, Pedersen-Bjergaard J.

    Haematologica. 1998 Jun;83(6):483-8.PMID: 9676019 [PubMed - indexed for MEDLINE]Related articlesFree article

    29.

    Secondary or therapy-related MDS and AML and their chromosome aberrations: important to study but difficult to establish causality.

    Pedersen-Bjergaard J, Andersen MK.

    Haematologica. 1998 Jun;83(6):481-2. Review. No abstract available. PMID: 9676018 [PubMed - indexed for MEDLINE]Related articlesFree article

    30.

    Balanced chromosome aberrations in leukemias following chemotherapy with DNA-topoisomerase II inhibitors.

    Pedersen-Bjergaard J, Andersen MK, Johansson B.

    J Clin Oncol. 1998 May;16(5):1897-8. No abstract available. PMID: 9586907 [PubMed - indexed for MEDLINE]Related articles

    31.

    Inversion of chromosome 16 and uncommon rearrangements of the CBFB and MYH11 genes in therapy-related acute myeloid leukemia: rare events related to DNA-topoisomerase II inhibitors?

    Dissing M, Le Beau MM, Pedersen-Bjergaard J.

    J Clin Oncol. 1998 May;16(5):1890-6.PMID: 9586906 [PubMed - indexed for MEDLINE]Related articles

    32.

    The prognostic significance of chromosomal analysis and immunophenotyping in 117 patients with de novo acute myeloid leukemia.

    de Nully Brown P, Jurlander J, Pedersen-Bjergaard J, Victor MA, Geisler CH.

    Leuk Res. 1997 Oct;21(10):985-95.PMID: 9403009 [PubMed - indexed for MEDLINE]Related articles

    33.

    High risk of therapy-related leukemia after BEAM chemotherapy and autologous stem cell transplantation for previously treated lymphomas is mainly related to primary chemotherapy and not to the BEAM-transplantation procedure.

    Pedersen-Bjergaard J, Pedersen M, Myhre J, Geisler C.

    Leukemia. 1997 Oct;11(10):1654-60.PMID: 9324285 [PubMed - indexed for MEDLINE]Related articles

    34.

    Chemotherapy-related - late occurring - Philadelphia chromosome in AML, ALL and CML. Similar events related to treatment with DNA topoisomerase II inhibitors?

    Pedersen-Bjergaard J, Brøndum-Nielsen K, Karle H, Johansson B.

    Leukemia. 1997 Sep;11(9):1571-4.PMID: 9305614 [PubMed - indexed for MEDLINE]Related articles

    35.

    Long-term survival and development of secondary malignancies in patients with acute myeloid leukemia treated with aclarubicin or daunorubicin plus cytosine arabinoside followed by intensive consolidation chemotherapy in a Danish national phase III trial. Danish Society of Haematology Study Group on AML.

    de Nully Brown P, Hoffmann T, Hansen OP, Boesen AM, Grønbaek K, Hippe E, Jensen MK, Thorling K, Storm HH, Pedersen-Bjergaard J.

    Leukemia. 1997 Jan;11(1):37-41.PMID: 9001416 [PubMed - indexed for MEDLINE]Related articles

    36.

    Partial tandem duplication of ALL1 as a recurrent molecular defect in acute myeloid leukemia with trisomy 11.

    Caligiuri MA, Strout MP, Schichman SA, Mrózek K, Arthur DC, Herzig GP, Baer MR, Schiffer CA, Heinonen K, Knuutila S, Nousiainen T, Ruutu T, Block AW, Schulman P, Pedersen-Bjergaard J, Croce CM, Bloomfield CD.

    Cancer Res. 1996 Mar 15;56(6):1418-25.PMID: 8640834 [PubMed - indexed for MEDLINE]Related articlesFree article

    37.

    [Molecular biology in acute myeloid leukemia]

    Hoffmann L, Jacobsen N, Nerlov C, Pedersen M, Pedersen-Bjergaard J.

    Ugeskr Laeger. 1996 Jan 1;158(1):26-9. Danish. No abstract available. PMID: 8560619 [PubMed - indexed for MEDLINE]Related articles

    38.

    Molecular characterization of 12p abnormalities in hematologic malignancies: deletion of KIP1, rearrangement of TEL, and amplification of CCND2.

    Höglund M, Johansson B, Pedersen-Bjergaard J, Marynen P, Mitelman F.

    Blood. 1996 Jan 1;87(1):324-30.PMID: 8547659 [PubMed - indexed for MEDLINE]Related articlesFree article

    39.

    Different genetic pathways in leukemogenesis for patients presenting with therapy-related myelodysplasia and therapy-related acute myeloid leukemia.

    Pedersen-Bjergaard J, Pedersen M, Roulston D, Philip P.

    Blood. 1995 Nov 1;86(9):3542-52.PMID: 7579462 [PubMed - indexed for MEDLINE]Related articlesFree article

    40.

    Therapy-related acute promyelocytic leukemia with t(15;17) (q22;q12) following chemotherapy with drugs targeting DNA topoisomerase II. A report of two cases and a review of the literature.

    Hoffmann L, Möller P, Pedersen-Bjergaard J, Waage A, Pedersen M, Hirsch FR.

    Ann Oncol. 1995 Oct;6(8):781-8. Review.PMID: 8589015 [PubMed - indexed for MEDLINE]Related articles

    41.

    Acute promyelocytic leukemia with t(15;17) following inhibition of DNA topoisomerase II.

    Pedersen-Bjergaard J.

    Ann Oncol. 1995 Oct;6(8):751-3. No abstract available. PMID: 8589010 [PubMed - indexed for MEDLINE]Related articles

    42.

    Long-term complications of cancer chemotherapy.

    Pedersen-Bjergaard J.

    J Clin Oncol. 1995 Jul;13(7):1534-6. No abstract available. PMID: 7602341 [PubMed - indexed for MEDLINE]Related articles

    43.

    Leiomyosarcoma of the urinary bladder after cyclophosphamide.

    Pedersen-Bjergaard J, Jønsson V, Pedersen M, Hou-Jensen K.

    J Clin Oncol. 1995 Feb;13(2):532-3. No abstract available. PMID: 7844616 [PubMed - indexed for MEDLINE]Related articles

    44.

    Therapy-related myelodysplasia and acute leukemia.

    Pedersen-Bjergaard J.

    Leuk Lymphoma. 1995;15 Suppl 1:11-2. Review. No abstract available. PMID: 7767250 [PubMed - indexed for MEDLINE]Related articles

    45.

    Translocation (3;21)(q26;q22) in therapy-related myelodysplasia following drugs targeting DNA-topoisomerase II combined with alkylating agents, and in myeloproliferative disorders undergoing spontaneous leukemic transformation.

    Pedersen-Bjergaard J, Johansson B, Philip P.

    Cancer Genet Cytogenet. 1994 Aug;76(1):50-5. Review.PMID: 8076352 [PubMed - indexed for MEDLINE]Related articles

    46.

    The balanced and the unbalanced chromosome aberrations of acute myeloid leukemia may develop in different ways and may contribute differently to malignant transformation.

    Pedersen-Bjergaard J, Rowley JD.

    Blood. 1994 May 15;83(10):2780-6. Review.PMID: 8180374 [PubMed - indexed for MEDLINE]Related articlesFree article

    47.

    Consistent intergenic splicing and production of multiple transcripts between AML1 at 21q22 and unrelated genes at 3q26 in (3;21)(q26;q22) translocations.

    Nucifora G, Begy CR, Kobayashi H, Roulston D, Claxton D, Pedersen-Bjergaard J, Parganas E, Ihle JN, Rowley JD.

    Proc Natl Acad Sci U S A. 1994 Apr 26;91(9):4004-8.PMID: 8171026 [PubMed - indexed for MEDLINE]Related articlesFree article

    48.

    Rearrangements of the MLL gene in therapy-related acute myeloid leukemia in patients previously treated with agents targeting DNA-topoisomerase II.

    Super HJ, McCabe NR, Thirman MJ, Larson RA, Le Beau MM, Pedersen-Bjergaard J, Philip P, Diaz MO, Rowley JD.

    Blood. 1993 Dec 15;82(12):3705-11.PMID: 8260707 [PubMed - indexed for MEDLINE]Related articlesFree article

    49.

    Therapy-related myelodysplasia and acute myeloid leukemia. Cytogenetic characteristics of 115 consecutive cases and risk in seven cohorts of patients treated intensively for malignant diseases in the Copenhagen series.

    Pedersen-Bjergaard J, Philip P, Larsen SO, Andersson M, Daugaard G, Ersbøll J, Hansen SW, Hou-Jensen K, Nielsen D, Sigsgaard TC, et al.

    Leukemia. 1993 Dec;7(12):1975-86.PMID: 8255096 [PubMed - indexed for MEDLINE]Related articles

    50.

    The dioxopiperazine derivatives, their leukemogenic potential and other biological effects.

    Pedersen-Bjergaard J.

    Leuk Res. 1992 Nov;16(11):1057-9. No abstract available. PMID: 1434741 [PubMed - indexed for MEDLINE]Related articles

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