PubMed

Initiating insulin therapy in type 2 diabetic patients failing on oral hypoglycemic agents: basal or prandial insulin? The APOLLO trial and beyond.

Bretzel RG, Eckhard M, Landgraf W, Owens DR, Linn T.

Diabetes Care. 2009 Nov;32 Suppl 2:S260-5. No abstract available. PMID: 19875561 [PubMed - in process]Related articles

Relative and absolute contributions of postprandial and fasting plasma glucose to daytime hyperglycaemia and HbA(1c) in subjects with Type 2 diabetes.

Peter R, Dunseath G, Luzio SD, Chudleigh R, Choudhury SR, Owens DR.

Diabet Med. 2009 Oct;26(10):974-80.PMID: 19900228 [PubMed - in process]Related articles

Regulation of oxidative stress by glycaemic control: evidence for an independent inhibitory effect of insulin therapy.

Monnier L, Colette C, Mas E, Michel F, Cristol JP, Boegner C, Owens DR.

Diabetologia. 2009 Nov 5. [Epub ahead of print]PMID: 19890623 [PubMed - as supplied by publisher]Related articles

Glycemic variability: the third component of the dysglycemia in diabetes. Is it important? How to measure it?

Monnier L, Colette C, Owens DR.

J Diabetes Sci Technol. 2008 Nov;2(6):1094-100.PMID: 19885298 [PubMed - in process]Free article

Consensus report of the coalition for clinical research-self-monitoring of blood glucose.

Klonoff DC, Bergenstal R, Blonde L, Boren SA, Church TS, Gaffaney J, Jovanovic L, Kendall DM, Kollman C, Kovatchev BP, Leippert C, Ddg D, Owens DR, Polonsky WH, Reach G, Renard E, Riddell MC, Rubin RR, Schnell O, Siminiero LM, Vigersky RA, Wilson DM, Wollitzer AO.

J Diabetes Sci Technol. 2008 Nov;2(6):1030-53.PMID: 19885292 [PubMed - in process]Free article

Reply to DeVries.

Owens DR, Bolli GB.

Diabetes Technol Ther. 2009 Feb;11(2):129. No abstract available. PMID: 19848581 [PubMed - in process]Related articles

The glucose lowering effect of an oral insulin (Capsulin) during an isoglycaemic clamp study in persons with type 2 diabetes.

Luzio SD, Dunseath G, Lockett A, Broke-Smith TP, New RR, Owens DR.

Diabetes Obes Metab. 2009 Sep 25. [Epub ahead of print]PMID: 19788433 [PubMed - as supplied by publisher]Related articles

Complex interplay between insulinemia, glycemia, and glomerular filtration rate in nondiabetic renal transplant recipients.

Sharif A, Ravindran V, Moore RH, Baboolal K, Dunseath G, Luzio S, Owens DR.

Transplantation. 2009 Jul 27;88(2):290-2. No abstract available. PMID: 19623029 [PubMed - indexed for MEDLINE]Related articles

Insulin hyposecretion in nondiabetic, tacrolimus-treated renal transplant recipients more than 6 months posttransplantation.

Ravindran VK, Moore RH, Dunseath G, Luzio SD, Owens DR, Baboolal K.

Transplantation. 2009 Jun 27;87(12):1870-6.PMID: 19543067 [PubMed - indexed for MEDLINE]Related articles

Integrating glycaemic variability in the glycaemic disorders of type 2 diabetes: a move towards a unified glucose tetrad concept.

Monnier L, Colette C, Owens DR.

Diabetes Metab Res Rev. 2009 Jul;25(5):393-402. Review.PMID: 19437415 [PubMed - indexed for MEDLINE]Related articles

Use of cystatin C-based estimations of glomerular filtration rate in patients with type 2 diabetes.

Chudleigh RA, Ollerton RL, Dunseath G, Peter R, Harvey JN, Luzio S, Owens DR.

Diabetologia. 2009 Jul;52(7):1274-8. Epub 2009 May 9.PMID: 19430759 [PubMed - indexed for MEDLINE]Related articles

Postprandial glucose - a potential therapeutic target to reduce cardiovascular mortality.

Peter R, Okoseime OE, Rees A, Owens DR.

Curr Vasc Pharmacol. 2009 Jan;7(1):68-74. Review.PMID: 19149642 [PubMed - indexed for MEDLINE]Related articles

Beyond the era of NPH insulin--long-acting insulin analogs: chemistry, comparative pharmacology, and clinical application.

Owens DR, Bolli GB.

Diabetes Technol Ther. 2008 Oct;10(5):333-49. Review.PMID: 18715209 [PubMed - indexed for MEDLINE]Related articles

Performance of the revised '175' Modification of Diet in Renal Disease equation in patients with type 2 diabetes.

Chudleigh RA, Ollerton RL, Dunseath G, Peter R, Harvey JN, Luzio S, Owens DR.

Diabetologia. 2008 Sep;51(9):1714-8. Epub 2008 Jul 17.PMID: 18633593 [PubMed - indexed for MEDLINE]Related articles

Simultaneous trend analysis for evaluating outcomes in patient-centred health monitoring services.

Conley EC, Owens DR, Luzio SL, Subramanian M, Ali AS, Hardisty A, Rana O.

Health Care Manag Sci. 2008 Jun;11(2):152-66.PMID: 18581822 [PubMed - indexed for MEDLINE]Related articles

Type 2 diabetes: a well-characterised but suboptimally controlled disease. Can we bridge the divide?

Monnier L, Colette C, Owens DR.

Diabetes Metab. 2008 Jun;34(3):207-16. Epub 2008 Jun 3. Review.PMID: 18511324 [PubMed - indexed for MEDLINE]Related articlesFree article

Once-daily basal insulin glargine versus thrice-daily prandial insulin lispro in people with type 2 diabetes on oral hypoglycaemic agents (APOLLO): an open randomised controlled trial.

Bretzel RG, Nuber U, Landgraf W, Owens DR, Bradley C, Linn T.

Lancet. 2008 Mar 29;371(9618):1073-84. Erratum in: Lancet. 2008 Aug 30;372(9640):718. PMID: 18374840 [PubMed - indexed for MEDLINE]Related articles

A comparison of preprandial insulin glulisine versus insulin lispro in people with Type 2 diabetes over a 12-h period.

Luzio S, Peter R, Dunseath GJ, Mustafa L, Owens DR.

Diabetes Res Clin Pract. 2008 Feb;79(2):269-75. Epub 2007 Dec 27.PMID: 18164094 [PubMed - indexed for MEDLINE]Related articles

Can pulsatile ocular blood flow distinguish between patients with and without diabetic retinopathy?

Perrott RL, Drasdo N, Owens DR, North RV.

Clin Exp Optom. 2007 Nov;90(6):445-50.PMID: 17958567 [PubMed - indexed for MEDLINE]Related articles

Influence of body weight on the performance of glomerular filtration rate estimators in subjects with type 2 diabetes.

Chudleigh RA, Dunseath G, Peter R, Harvey JN, Ollerton RL, Luzio S, Owens DR.

Diabetes Care. 2008 Jan;31(1):47-9. Epub 2007 Oct 12. No abstract available. PMID: 17934154 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of pharmacokinetics and dynamics of the long-acting insulin analogs glargine and detemir at steady state in type 1 diabetes: a double-blind, randomized, crossover study.

Porcellati F, Rossetti P, Busciantella NR, Marzotti S, Lucidi P, Luzio S, Owens DR, Bolli GB, Fanelli CG.

Diabetes Care. 2007 Oct;30(10):2447-52. Epub 2007 Jul 10. Erratum in: Diabetes Care. 2008 Jan;31(1):188. PMID: 17623819 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin resistance and inflammation - A further systemic complication of COPD.

Bolton CE, Evans M, Ionescu AA, Edwards SM, Morris RH, Dunseath G, Luzio SD, Owens DR, Shale DJ.

COPD. 2007 Jun;4(2):121-6.PMID: 17530505 [PubMed - indexed for MEDLINE]Related articles

Alchemist multimodal workflows for diabetic retinopathy research, disease prevention and investigational drug discovery.

Riposan A, Taylor I, Owens DR, Rana O, Conley EC.

Stud Health Technol Inform. 2007;126:279-88.PMID: 17476070 [PubMed - indexed for MEDLINE]Related articles

How reliable is estimation of glomerular filtration rate at diagnosis of type 2 diabetes?

Chudleigh RA, Dunseath G, Evans W, Harvey JN, Evans P, Ollerton R, Owens DR.

Diabetes Care. 2007 Feb;30(2):300-5.PMID: 17259498 [PubMed - indexed for MEDLINE]Related articlesFree article

The loss of postprandial glycemic control precedes stepwise deterioration of fasting with worsening diabetes.

Monnier L, Colette C, Dunseath GJ, Owens DR.

Diabetes Care. 2007 Feb;30(2):263-9.PMID: 17259492 [PubMed - indexed for MEDLINE]Related articlesFree article

Results of the pilot study of DIADEM: a comprehensive disease management programme for type 2 diabetes.

Luzio S, Piehlmeier W, Tovar C, Eberl S, Lätzsch G, Fallböhmer E, Rumpel E, Owens DR, Landgraf R.

Diabetes Res Clin Pract. 2007 Jun;76(3):410-7. Epub 2006 Nov 3.PMID: 17084478 [PubMed - indexed for MEDLINE]Related articles

Relationship between HbA1c and indices of glucose tolerance derived from a standardized meal test in newly diagnosed treatment naive subjects with Type 2 diabetes.

Peter R, Luzio SD, Dunseath G, Pauvaday V, Mustafa N, Owens DR.

Diabet Med. 2006 Sep;23(9):990-5.PMID: 16922705 [PubMed - indexed for MEDLINE]Related articles

Inhaled human insulin.

Owens DR, Grimley J, Kirkpatrick P.

Nat Rev Drug Discov. 2006 May;5(5):371-2. No abstract available. PMID: 16802444 [PubMed - indexed for MEDLINE]Related articles

Comparison of the pharmacokinetics and pharmacodynamics of biphasic insulin aspart and insulin glargine in people with type 2 diabetes.

Luzio S, Dunseath G, Peter R, Pauvaday V, Owens DR.

Diabetologia. 2006 Jun;49(6):1163-8. Epub 2006 Apr 5.PMID: 16596358 [PubMed - indexed for MEDLINE]Related articles

Postprandial glucose regulation: new data and new implications.

Leiter LA, Ceriello A, Davidson JA, Hanefeld M, Monnier L, Owens DR, Tajima N, Tuomilehto J; International Prandial Glucose Regulation Study Group.

Clin Ther. 2005;27 Suppl B:S42-56. Review.PMID: 16519037 [PubMed - indexed for MEDLINE]Related articles

The systemic inflammatory response to exercise in adults with cystic fibrosis.

Ionescu AA, Mickleborough TD, Bolton CE, Lindley MR, Nixon LS, Dunseath G, Luzio S, Owens DR, Shale DJ.

J Cyst Fibros. 2006 May;5(2):105-12. Epub 2006 Jan 3.PMID: 16403491 [PubMed - indexed for MEDLINE]Related articles

Silent substitution S-cone electroretinogram in subjects with diabetes mellitus.

Mortlock KE, Chiti Z, Drasdo N, Owens DR, North RV.

Ophthalmic Physiol Opt. 2005 Sep;25(5):392-9.PMID: 16101944 [PubMed - indexed for MEDLINE]Related articles

Contribution of fasting and postprandial plasma glucose to HbA1c.

Ollerton RL, Luzio SD, Owens DR.

Diabet Med. 2005 Jul;22(7):954-5. No abstract available. PMID: 15975115 [PubMed - indexed for MEDLINE]Related articles

Quality assurance for diabetic retinopathy telescreening.

Schneider S, Aldington SJ, Kohner EM, Luzio S, Owens DR, Schmidt V, Schuell H, Zahlmann G.

Diabet Med. 2005 Jun;22(6):794-802.PMID: 15910634 [PubMed - indexed for MEDLINE]Related articles

Anemia and diabetes in the absence of nephropathy.

Craig KJ, Williams JD, Riley SG, Smith H, Owens DR, Worthing D, Cavill I, Phillips AO.

Diabetes Care. 2005 May;28(5):1118-23.PMID: 15855576 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta-cell response during a meal test: a comparative study of incremental doses of repaglinide in type 2 diabetic patients.

Cozma LS, Luzio SD, Dunseath GJ, Underwood PM, Owens DR.

Diabetes Care. 2005 May;28(5):1001-7.PMID: 15855557 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of exercise on the absorption of insulin glargine in patients with type 1 diabetes.

Peter R, Luzio SD, Dunseath G, Miles A, Hare B, Backx K, Pauvaday V, Owens DR.

Diabetes Care. 2005 Mar;28(3):560-5.PMID: 15735188 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of post prandial glucose changes on oscillatory potentials in subjects with type 2 diabetes mellitus.

Arlotte DV, Perrott RL, Drasdo N, Owens DR, North RV.

Doc Ophthalmol. 2004 Jul;109(1):35-42.PMID: 15675198 [PubMed - indexed for MEDLINE]Related articles

The quest for physiologic insulin replacement.

Owens DR.

Postgrad Med. 2004 Nov;116(5 Suppl Exploring):4-12.PMID: 19667674 [PubMed - indexed for MEDLINE]Related articles

Feasibility of using the TOSCA telescreening procedures for diabetic retinopathy.

Luzio S, Hatcher S, Zahlmann G, Mazik L, Morgan M, Liesenfeld B, Bek T, Schuell H, Schneider S, Owens DR, Kohner E.

Diabet Med. 2004 Oct;21(10):1121-8.PMID: 15384960 [PubMed - indexed for MEDLINE]Related articles

Population and individual minimal modeling of the frequently sampled insulin-modified intravenous glucose tolerance test.

Erichsen L, Agbaje OF, Luzio SD, Owens DR, Hovorka R.

Metabolism. 2004 Oct;53(10):1349-54.PMID: 15375793 [PubMed - indexed for MEDLINE]Related articles

A placebo-controlled crossover study comparing the effects of nateglinide and glibenclamide on postprandial hyperglycaemia and hyperinsulinaemia in patients with type 2 diabetes.

Barnett AH, Anderson DM, Shelley S, Morgan R, Owens DR.

Diabetes Obes Metab. 2004 Mar;6(2):104-13.PMID: 14746575 [PubMed - indexed for MEDLINE]Related articles

Alternative routes of insulin delivery.

Owens DR, Zinman B, Bolli G.

Diabet Med. 2003 Nov;20(11):886-98. Review.PMID: 14632713 [PubMed - indexed for MEDLINE]Related articles

Comparison of the subcutaneous absorption of insulin glargine (Lantus) and NPH insulin in patients with Type 2 diabetes.

Luzio SD, Beck P, Owens DR.

Horm Metab Res. 2003 Jul;35(7):434-8.PMID: 12931275 [PubMed - indexed for MEDLINE]Related articles

Bayesian hierarchical approach to estimate insulin sensitivity by minimal model.

Agbaje OF, Luzio SD, Albarrak AI, Lunn DJ, Owens DR, Hovorka R.

Clin Sci (Lond). 2003 Nov;105(5):551-60.PMID: 12790795 [PubMed - indexed for MEDLINE]Related articles

Identification and management of diabetic nephropathy in the diabetes clinic.

Craig KJ, Donovan K, Munnery M, Owens DR, Williams JD, Phillips AO.

Diabetes Care. 2003 Jun;26(6):1806-11.PMID: 12766114 [PubMed - indexed for MEDLINE]Related articlesFree article

The pharmacokinetics of s.c. Semitard MC, human NPH ge, Rapitard MC and human NPH 30:70 ge insulin in healthy, non-diabetic subjects.

Luzio SD, George L, Beck P, Chester P, Owens DR.

Eur J Intern Med. 2003 Mar;14(2):107-112.PMID: 12719028 [PubMed - as supplied by publisher]Related articles

Early-phase prandial insulin secretion: its role in the pathogenesis of type 2 diabetes mellitus and its modulation by repaglinide.

Owens DR, Cozma LS, Luzio SD.

Diabetes Nutr Metab. 2002 Dec;15(6 Suppl):19-27. Review.PMID: 12702004 [PubMed - indexed for MEDLINE]Related articles

Automated detection of fundus photographic red lesions in diabetic retinopathy.

Larsen M, Godt J, Larsen N, Lund-Andersen H, Sjølie AK, Agardh E, Kalm H, Grunkin M, Owens DR.

Invest Ophthalmol Vis Sci. 2003 Feb;44(2):761-6.PMID: 12556411 [PubMed - indexed for MEDLINE]Related articlesFree article

Perceptions of diabetic retinopathy and screening procedures among diabetic people.

Trento M, Bajardi M, Borgo E, Passera P, Maurino M, Gibbins R, Owens DR, Cavallo F, Porta M.

Diabet Med. 2002 Oct;19(10):810-3.PMID: 12358866 [PubMed - indexed for MEDLINE]Related articles