PubMed

Interferon regulatory factor-1 is a key transcription factor in murine beta cells under immune attack.

Gysemans C, Callewaert H, Moore F, Nelson-Holte M, Overbergh L, Eizirik DL, Mathieu C.

Diabetologia. 2009 Sep 8. [Epub ahead of print]PMID: 19756487 [PubMed - as supplied by publisher]Related articles

Proteome analysis demonstrates profound alterations in human dendritic cell nature by TX527, an analogue of vitamin D.

Ferreira GB, van Etten E, Lage K, Hansen DA, Moreau Y, Workman CT, Waer M, Verstuyf A, Waelkens E, Overbergh L, Mathieu C.

Proteomics. 2009 Jul;9(14):3752-64.PMID: 19639594 [PubMed - indexed for MEDLINE]Related articles

Cluster analysis of rat pancreatic islet gene mRNA levels after culture in low-, intermediate- and high-glucose concentrations.

Bensellam M, Van Lommel L, Overbergh L, Schuit FC, Jonas JC.

Diabetologia. 2009 Mar;52(3):463-76. Epub 2009 Jan 23.PMID: 19165461 [PubMed - indexed for MEDLINE]Related articles

Regulation of vitamin D homeostasis: implications for the immune system.

van Etten E, Stoffels K, Gysemans C, Mathieu C, Overbergh L.

Nutr Rev. 2008 Oct;66(10 Suppl 2):S125-34. Review.PMID: 18844839 [PubMed - indexed for MEDLINE]Related articles

Vitamin D signaling in immune-mediated disorders: Evolving insights and therapeutic opportunities.

Baeke F, van Etten E, Gysemans C, Overbergh L, Mathieu C.

Mol Aspects Med. 2008 Dec;29(6):376-87. Epub 2008 Jul 14. Review.PMID: 18621414 [PubMed - indexed for MEDLINE]Related articles

Initiation and execution of lipotoxic ER stress in pancreatic beta-cells.

Cunha DA, Hekerman P, Ladrière L, Bazarra-Castro A, Ortis F, Wakeham MC, Moore F, Rasschaert J, Cardozo AK, Bellomo E, Overbergh L, Mathieu C, Lupi R, Hai T, Herchuelz A, Marchetti P, Rutter GA, Eizirik DL, Cnop M.

J Cell Sci. 2008 Jul 15;121(Pt 14):2308-18. Epub 2008 Jun 17.PMID: 18559892 [PubMed - indexed for MEDLINE]Related articlesFree article

T-cell mediated late increase in bronchial tone after allergen provocation in a murine asthma model.

Meyts I, Vanoirbeek JA, Hens G, Vanaudenaerde BM, Verbinnen B, Bullens DM, Overbergh L, Mathieu C, Ceuppens JL, Hellings PW.

Clin Immunol. 2008 Aug;128(2):248-58. Epub 2008 May 27.PMID: 18502692 [PubMed - indexed for MEDLINE]Related articles

The development of atopic dermatitis is independent of Immunoglobulin E up-regulation in the K14-IL-4 SKH1 transgenic mouse model.

Chen L, Overbergh L, Mathieu C, Chan LS.

Clin Exp Allergy. 2008 Aug;38(8):1367-80. Epub 2008 Apr 13.PMID: 18489026 [PubMed - indexed for MEDLINE]Related articles

Cytokine signalling in the beta-cell: a dual role for IFNgamma.

Gysemans C, Callewaert H, Overbergh L, Mathieu C.

Biochem Soc Trans. 2008 Jun;36(Pt 3):328-33. Review.PMID: 18481951 [PubMed - indexed for MEDLINE]Related articles

Effect of recombinant human TNF-binding protein-1 and GnRH antagonist on mRNA expression of inflammatory cytokines and adhesion and growth factors in endometrium and endometriosis tissues in baboons.

Kyama CM, Overbergh L, Mihalyi A, Cuneo S, Chai D, Debrock S, Mwenda JM, Mathieu C, Nugent NP, D'Hooghe TM.

Fertil Steril. 2008 May;89(5 Suppl):1306-13. Epub 2007 Dec 3.PMID: 18061171 [PubMed - indexed for MEDLINE]Related articles

Unaltered diabetes presentation in NOD mice lacking the vitamin D receptor.

Gysemans C, van Etten E, Overbergh L, Giulietti A, Eelen G, Waer M, Verstuyf A, Bouillon R, Mathieu C.

Diabetes. 2008 Jan;57(1):269-75. Epub 2007 Oct 24.PMID: 17959935 [PubMed - indexed for MEDLINE]Related articlesFree article

Proteomics analysis of cytokine-induced dysfunction and death in insulin-producing INS-1E cells: new insights into the pathways involved.

D'Hertog W, Overbergh L, Lage K, Ferreira GB, Maris M, Gysemans C, Flamez D, Cardozo AK, Van den Bergh G, Schoofs L, Arckens L, Moreau Y, Hansen DA, Eizirik DL, Waelkens E, Mathieu C.

Mol Cell Proteomics. 2007 Dec;6(12):2180-99. Epub 2007 Oct 5.PMID: 17921177 [PubMed - indexed for MEDLINE]Related articlesFree article

Endometrial and peritoneal expression of aromatase, cytokines, and adhesion factors in women with endometriosis.

Kyama CM, Overbergh L, Mihalyi A, Meuleman C, Mwenda JM, Mathieu C, D'Hooghe TM.

Fertil Steril. 2008 Feb;89(2):301-10. Epub 2007 Aug 6.PMID: 17678915 [PubMed - indexed for MEDLINE]Related articles

Neuropeptides of the islets of Langerhans: a peptidomics study.

Boonen K, Baggerman G, D'Hertog W, Husson SJ, Overbergh L, Mathieu C, Schoofs L.

Gen Comp Endocrinol. 2007 Jun-Jul;152(2-3):231-41. Epub 2007 May 8.PMID: 17559849 [PubMed - indexed for MEDLINE]Related articles

Vitamin D3 and the immune system: maintaining the balance in health and disease.

Baeke F, Etten EV, Overbergh L, Mathieu C.

Nutr Res Rev. 2007 Jun;20(1):106-18.PMID: 19079863 [PubMed - in process]Related articles

Deletion of STAT-1 pancreatic islets protects against streptozotocin-induced diabetes and early graft failure but not against late rejection.

Callewaert HI, Gysemans CA, Ladrière L, D'Hertog W, Hagenbrock J, Overbergh L, Eizirik DL, Mathieu C.

Diabetes. 2007 Aug;56(8):2169-73. Epub 2007 May 1.PMID: 17473223 [PubMed - indexed for MEDLINE]Related articlesFree article

The vitamin D receptor gene FokI polymorphism: functional impact on the immune system.

van Etten E, Verlinden L, Giulietti A, Ramos-Lopez E, Branisteanu DD, Ferreira GB, Overbergh L, Verstuyf A, Bouillon R, Roep BO, Badenhoop K, Mathieu C.

Eur J Immunol. 2007 Feb;37(2):395-405.PMID: 17274004 [PubMed - indexed for MEDLINE]Related articles

Immune regulation of 1alpha-hydroxylase in murine peritoneal macrophages: unravelling the IFNgamma pathway.

Stoffels K, Overbergh L, Bouillon R, Mathieu C.

J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):567-71. Epub 2006 Dec 27.PMID: 17267208 [PubMed - indexed for MEDLINE]Related articles

Novel insights in the immune function of the vitamin D system: synergism with interferon-beta.

van Etten E, Gysemans C, Branisteanu DD, Verstuyf A, Bouillon R, Overbergh L, Mathieu C.

J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):546-51. Epub 2006 Dec 23.PMID: 17254771 [PubMed - indexed for MEDLINE]Related articles

Monocytes from type 2 diabetic patients have a pro-inflammatory profile. 1,25-Dihydroxyvitamin D(3) works as anti-inflammatory.

Giulietti A, van Etten E, Overbergh L, Stoffels K, Bouillon R, Mathieu C.

Diabetes Res Clin Pract. 2007 Jul;77(1):47-57. Epub 2006 Nov 16.PMID: 17112620 [PubMed - indexed for MEDLINE]Related articles

IL-12 contributes to allergen-induced airway inflammation in experimental asthma.

Meyts I, Hellings PW, Hens G, Vanaudenaerde BM, Verbinnen B, Heremans H, Matthys P, Bullens DM, Overbergh L, Mathieu C, De Boeck K, Ceuppens JL.

J Immunol. 2006 Nov 1;177(9):6460-70.PMID: 17056578 [PubMed - indexed for MEDLINE]Related articlesFree article

IL-10- and IL-12-independent down-regulation of allergic sensitization by stimulation of CD40 signaling.

Hellings PW, Kasran A, Bullens D, Overbergh L, Mathieu C, Heremans H, Matthys P, Boon L, Jorissen M, Ceuppens JL.

J Immunol. 2006 Oct 15;177(8):5138-44.PMID: 17015698 [PubMed - indexed for MEDLINE]Related articlesFree article

Immune regulation of 25-hydroxyvitamin D-1alpha-hydroxylase in human monocytic THP1 cells: mechanisms of interferon-gamma-mediated induction.

Overbergh L, Stoffels K, Waer M, Verstuyf A, Bouillon R, Mathieu C.

J Clin Endocrinol Metab. 2006 Sep;91(9):3566-74. Epub 2006 Jun 20.PMID: 16787983 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased peritoneal and endometrial gene expression of biologically relevant cytokines and growth factors during the menstrual phase in women with endometriosis.

Kyama CM, Overbergh L, Debrock S, Valckx D, Vander Perre S, Meuleman C, Mihalyi A, Mwenda JM, Mathieu C, D'Hooghe TM.

Fertil Steril. 2006 Jun;85(6):1667-75.PMID: 16759923 [PubMed - indexed for MEDLINE]Related articles

CCL27 is a critical factor for the development of atopic dermatitis in the keratin-14 IL-4 transgenic mouse model.

Chen L, Lin SX, Agha-Majzoub R, Overbergh L, Mathieu C, Chan LS.

Int Immunol. 2006 Aug;18(8):1233-42. Epub 2006 May 30.PMID: 16735375 [PubMed - indexed for MEDLINE]Related articlesFree article

Type 1 diabetes: entering the proteomic era.

D'Hertog W, Mathieu C, Overbergh L.

Expert Rev Proteomics. 2006 Apr;3(2):223-36. Review.PMID: 16608435 [PubMed - indexed for MEDLINE]Related articles

UVB-induced 1,25(OH)2D3 production and vitamin D activity in intestinal CaCo-2 cells and in THP-1 macrophages pretreated with a sterol Delta7-reductase inhibitor.

Vantieghem K, Overbergh L, Carmeliet G, De Haes P, Bouillon R, Segaert S.

J Cell Biochem. 2006 Sep 1;99(1):229-40.PMID: 16598763 [PubMed - indexed for MEDLINE]Related articles

Evaluation of airway inflammation by quantitative Th1/Th2 cytokine mRNA measurement in sputum of asthma patients.

Truyen E, Coteur L, Dilissen E, Overbergh L, Dupont LJ, Ceuppens JL, Bullens DM.

Thorax. 2006 Mar;61(3):202-8. Epub 2006 Jan 31.PMID: 16449261 [PubMed - indexed for MEDLINE]Related articlesFree article

Involvement of 4-1BB (CD137)-4-1BBligand interaction in the modulation of CD4 T cell-mediated inflammatory colitis.

Maerten P, Kwon BS, Shen C, De Hertogh G, Cadot P, Bullens DM, Overbergh L, Mathieu C, Van Assche G, Geboes K, Rutgeerts P, Ceuppens JL.

Clin Exp Immunol. 2006 Feb;143(2):228-36.PMID: 16412046 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantification of chemokines by real-time reverse transcriptase PCR: applications in type 1 diabetes.

Overbergh L, Gysemans C, Mathieu C.

Expert Rev Mol Diagn. 2006 Jan;6(1):51-64. Review.PMID: 16359267 [PubMed - indexed for MEDLINE]Related articles

Immune regulation of 25-hydroxyvitamin-D3-1alpha-hydroxylase in human monocytes.

Stoffels K, Overbergh L, Giulietti A, Verlinden L, Bouillon R, Mathieu C.

J Bone Miner Res. 2006 Jan;21(1):37-47. Epub 2005 Sep 19.PMID: 16355272 [PubMed - indexed for MEDLINE]Related articles

Stimulation of A2A-adenosine receptors after myocardial infarction suppresses inflammatory activation and attenuates contractile dysfunction in the remote left ventricle.

Toufektsian MC, Yang Z, Prasad KM, Overbergh L, Ramos SI, Mathieu C, Linden J, French BA.

Am J Physiol Heart Circ Physiol. 2006 Apr;290(4):H1410-8. Epub 2005 Nov 11.PMID: 16284233 [PubMed - indexed for MEDLINE]Related articlesFree article

The disease progression in the keratin 14 IL-4-transgenic mouse model of atopic dermatitis parallels the up-regulation of B cell activation molecules, proliferation and surface and serum IgE.

Chen L, Lin SX, Overbergh L, Mathieu C, Chan LS.

Clin Exp Immunol. 2005 Oct;142(1):21-30.PMID: 16178852 [PubMed - indexed for MEDLINE]Related articlesFree article

Validation of real-time RT-PCR assays for mRNA quantification in baboons.

Overbergh L, Kyama CM, Valckx D, Debrock S, Mwenda JM, Mathieu C, D'Hooghe T.

Cytokine. 2005 Sep 21;31(6):454-8.PMID: 16129617 [PubMed - indexed for MEDLINE]Related articles

Blockade of CTLA-4 (CD152) enhances the murine antibody response to pneumococcal capsular polysaccharides.

Boudewijns M, Jeurissen A, Wuyts M, Moens L, Boon L, Van Neerven JJ, Kasran A, Overbergh L, Lenaerts C, Waer M, Mathieu C, Ceuppens JL, Bossuyt X.

J Leukoc Biol. 2005 Nov;78(5):1060-9. Epub 2005 Aug 4.PMID: 16081596 [PubMed - indexed for MEDLINE]Related articlesFree article

1Alpha,25-dihydroxyvitamin D3 restores thymocyte apoptosis sensitivity in non-obese diabetic (NOD) mice through dendritic cells.

Decallonne B, van Etten E, Overbergh L, Valckx D, Bouillon R, Mathieu C.

J Autoimmun. 2005 Jun;24(4):281-9.PMID: 15913954 [PubMed - indexed for MEDLINE]Related articles

1alpha,25-Dihydroxyvitamin D3 modulates the murine antibody response to pneumococcal capsular polysaccharide serotype 3 through IL-12.

Jeurissen A, Van Etten E, Overbergh L, Wuyts G, Heremans H, Matthys P, Ceuppens JL, Mathieu C, Bossuyt X.

Eur J Immunol. 2005 Jun;35(6):1841-8.PMID: 15909307 [PubMed - indexed for MEDLINE]Related articles

1,25-Dihydroxyvitamin D3 alters the profile of bone marrow-derived dendritic cells of NOD mice.

van Etten E, Dardenne O, Gysemans C, Overbergh L, Mathieu C.

Ann N Y Acad Sci. 2004 Dec;1037:186-92.PMID: 15699515 [PubMed - indexed for MEDLINE]Related articles

Monocytic expression behavior of cytokines in diabetic patients upon inflammatory stimulation.

Giulietti A, Stoffels K, Decallonne B, Overbergh L, Mathieu C.

Ann N Y Acad Sci. 2004 Dec;1037:74-8.PMID: 15699496 [PubMed - indexed for MEDLINE]Related articles

Early accumulation of interferon-gamma in grafts tolerized by donor-specific blood transfusion: friend or enemy?

Kitade H, Kawai M, Koshiba T, Giulietti A, Overbergh L, Rutgeerts O, Valckx D, Waer M, Mathieu C, Pirenne J.

Transplantation. 2004 Dec 27;78(12):1747-55.PMID: 15614147 [PubMed - indexed for MEDLINE]Related articles

Early up-regulation of Th2 cytokines and late surge of Th1 cytokines in an atopic dermatitis model.

Chen L, Martinez O, Overbergh L, Mathieu C, Prabhakar BS, Chan LS.

Clin Exp Immunol. 2004 Dec;138(3):375-87.PMID: 15544612 [PubMed - indexed for MEDLINE]Related articlesFree article

NOD macrophages produce high levels of inflammatory cytokines upon encounter of apoptotic or necrotic cells.

Stoffels K, Overbergh L, Giulietti A, Kasran A, Bouillon R, Gysemans C, Mathieu C.

J Autoimmun. 2004 Aug;23(1):9-15.PMID: 15236748 [PubMed - indexed for MEDLINE]Related articles

Regulation of 25-hydroxyvitamin d-1alpha-hydroxylase by IFNgamma in human monocytic THP1 cells.

Overbergh L, Stoffels K, Valckx D, Giulietti A, Bouillon R, Mathieu C.

J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):453-5.PMID: 15225819 [PubMed - indexed for MEDLINE]Related articles

Vitamin D and 1,25-dihydroxyvitamin D3 as modulators in the immune system.

Mathieu C, van Etten E, Decallonne B, Guilietti A, Gysemans C, Bouillon R, Overbergh L.

J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):449-52. Review.PMID: 15225818 [PubMed - indexed for MEDLINE]Related articles

Vitamin D deficiency in early life accelerates Type 1 diabetes in non-obese diabetic mice.

Giulietti A, Gysemans C, Stoffels K, van Etten E, Decallonne B, Overbergh L, Bouillon R, Mathieu C.

Diabetologia. 2004 Mar;47(3):451-62. Epub 2004 Jan 31.PMID: 14758446 [PubMed - indexed for MEDLINE]Related articles

Hen egg white lysozyme vaccination induces acute shock in NOD mice.

Branisteanu DD, Overbergh L, Decallonne B, Mathieu C.

Ann N Y Acad Sci. 2003 Nov;1005:215-7.PMID: 14679062 [PubMed - indexed for MEDLINE]Related articles

Regulatory cell-mediated tolerance does not protect against chronic rejection.

Koshiba T, Kitade H, Van Damme B, Giulietti A, Overbergh L, Mathieu C, Waer M, Pirenne J.

Transplantation. 2003 Aug 15;76(3):588-96.PMID: 12923449 [PubMed - indexed for MEDLINE]Related articles

The use of real-time reverse transcriptase PCR for the quantification of cytokine gene expression.

Overbergh L, Giulietti A, Valckx D, Decallonne R, Bouillon R, Mathieu C.

J Biomol Tech. 2003 Mar;14(1):33-43.PMID: 12901609 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevention of primary non-function of islet xenografts in autoimmune diabetic NOD mice by anti-inflammatory agents.

Gysemans C, Stoffels K, Giulietti A, Overbergh L, Waer M, Lannoo M, Feige U, Mathieu C.

Diabetologia. 2003 Aug;46(8):1115-23. Epub 2003 Jul 17.PMID: 12879250 [PubMed - indexed for MEDLINE]Related articles

Defect in activation-induced cell death in non-obese diabetic (NOD) T lymphocytes.

Decallonne B, van Etten E, Giulietti A, Casteels K, Overbergh L, Bouillon R, Mathieu C.

J Autoimmun. 2003 May;20(3):219-26.PMID: 12753807 [PubMed - indexed for MEDLINE]Related articles