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Adenosine receptors and the kidney.

Vallon V, Osswald H.

Handb Exp Pharmacol. 2009;(193):443-70. Review.PMID: 19639291 [PubMed - indexed for MEDLINE]Related articles

Determinants for the cAMP-binding site at the S-adenosylhomocysteine-hydrolase.

Kloor D, Hermes M, Kirschler J, Müller M, Hagen N, Kalbacher H, Stevanovic S, Osswald H.

Naunyn Schmiedebergs Arch Pharmacol. 2009 Sep;380(3):215-22. Epub 2009 Jun 23.PMID: 19547959 [PubMed - indexed for MEDLINE]Related articles

17beta-Estradiol modulates apoptosis in pancreatic beta-cells by specific involvement of the sulfonylurea receptor (SUR) isoform SUR1.

Ackermann S, Hiller S, Osswald H, Lösle M, Grenz A, Hambrock A.

J Biol Chem. 2009 Feb 20;284(8):4905-13. Epub 2008 Dec 18.PMID: 19095654 [PubMed - indexed for MEDLINE]Related articles

S-Adenosylhomocysteine hydrolase overexpression in HEK-293 cells: effect on intracellular adenosine levels, cell viability, and DNA methylation.

Hermes M, Osswald H, Riehle R, Piesch C, Kloor D.

Cell Physiol Biochem. 2008;22(1-4):223-36. Epub 2008 Jul 25.PMID: 18769049 [PubMed - indexed for MEDLINE]Related articles

Role of serum- and glucocorticoid-inducible kinase SGK1 in glucocorticoid regulation of renal electrolyte excretion and blood pressure.

Boini KM, Nammi S, Grahammer F, Osswald H, Kuhl D, Lang F.

Kidney Blood Press Res. 2008;31(4):280-9. Epub 2008 Aug 28.PMID: 18753797 [PubMed - indexed for MEDLINE]Related articles

The reno-vascular A2B adenosine receptor protects the kidney from ischemia.

Grenz A, Osswald H, Eckle T, Yang D, Zhang H, Tran ZV, Klingel K, Ravid K, Eltzschig HK.

PLoS Med. 2008 Jun 24;5(6):e137.PMID: 18578565 [PubMed - indexed for MEDLINE]Related articlesFree article

Alterations in S-adenosylhomocysteine metabolism decrease O6-methylguanine DNA methyltransferase gene expression without affecting promoter methylation.

Hermes M, Geisler H, Osswald H, Riehle R, Kloor D.

Biochem Pharmacol. 2008 Jun 1;75(11):2100-11. Epub 2008 Mar 8.PMID: 18395186 [PubMed - indexed for MEDLINE]Related articles

Vasopressin regulation of inner medullary collecting ducts and compensatory changes in mice lacking adenosine A1 receptors.

Rieg T, Pothula K, Schroth J, Satriano J, Osswald H, Schnermann J, Insel PA, Bundey RA, Vallon V.

Am J Physiol Renal Physiol. 2008 Mar;294(3):F638-44. Epub 2008 Jan 16.PMID: 18199602 [PubMed - indexed for MEDLINE]Related articlesFree article

Lack of effect of extracellular adenosine generation and signaling on renal erythropoietin secretion during hypoxia.

Grenz A, Zhang H, Weingart J, von Wietersheim S, Eckle T, Schnermann J, Köhle C, Kloor D, Gleiter CH, Vallon V, Eltzschig HK, Osswald H.

Am J Physiol Renal Physiol. 2007 Nov;293(5):F1501-11. Epub 2007 Sep 12.PMID: 17855480 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenosine metabolism and its effect on methylation potential in cultured cells: methodological considerations.

Hermes M, Osswald H, Kloor D.

Cell Mol Biol (Noisy-le-grand). 2007 Jan 21;52 Suppl:OL874-81.PMID: 17543225 [PubMed - indexed for MEDLINE]Related articles

The role of the BK channel in potassium homeostasis and flow-induced renal potassium excretion.

Rieg T, Vallon V, Sausbier M, Sausbier U, Kaissling B, Ruth P, Osswald H.

Kidney Int. 2007 Sep;72(5):566-73. Epub 2007 Jun 20.PMID: 17579662 [PubMed - indexed for MEDLINE]Related articles

Contribution of E-NTPDase1 (CD39) to renal protection from ischemia-reperfusion injury.

Grenz A, Zhang H, Hermes M, Eckle T, Klingel K, Huang DY, Müller CE, Robson SC, Osswald H, Eltzschig HK.

FASEB J. 2007 Sep;21(11):2863-73. Epub 2007 Apr 18.PMID: 17442731 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardioprotection by ecto-5'-nucleotidase (CD73) and A2B adenosine receptors.

Eckle T, Krahn T, Grenz A, Köhler D, Mittelbronn M, Ledent C, Jacobson MA, Osswald H, Thompson LF, Unertl K, Eltzschig HK.

Circulation. 2007 Mar 27;115(12):1581-90. Epub 2007 Mar 12.PMID: 17353435 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression and localization of S-adenosylhomocysteine-hydrolase in the rat kidney following carbon monoxide induced hypoxia.

Kloor D, Hermes M, Fink K, Schmid H, Klingel K, Mack A, Grenz A, Osswald H.

Cell Physiol Biochem. 2007;19(1-4):57-66.PMID: 17310100 [PubMed - indexed for MEDLINE]Related articles

Protective role of ecto-5'-nucleotidase (CD73) in renal ischemia.

Grenz A, Zhang H, Eckle T, Mittelbronn M, Wehrmann M, Köhle C, Kloor D, Thompson LF, Osswald H, Eltzschig HK.

J Am Soc Nephrol. 2007 Mar;18(3):833-45. Epub 2007 Jan 31.PMID: 17267736 [PubMed - indexed for MEDLINE]Related articlesFree article

Resveratrol binds to the sulfonylurea receptor (SUR) and induces apoptosis in a SUR subtype-specific manner.

Hambrock A, de Oliveira Franz CB, Hiller S, Grenz A, Ackermann S, Schulze DU, Drews G, Osswald H.

J Biol Chem. 2007 Feb 2;282(5):3347-56. Epub 2006 Nov 30.PMID: 17138562 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of S-adenosylhomocysteine hydrolase in adenosine-induced apoptosis in HepG2 cells.

Hermes M, Osswald H, Kloor D.

Exp Cell Res. 2007 Jan 15;313(2):264-83. Epub 2006 Oct 13.PMID: 17097637 [PubMed - indexed for MEDLINE]Related articles

Resistance of mice lacking the serum- and glucocorticoid-inducible kinase SGK1 against salt-sensitive hypertension induced by a high-fat diet.

Huang DY, Boini KM, Osswald H, Friedrich B, Artunc F, Ullrich S, Rajamanickam J, Palmada M, Wulff P, Kuhl D, Vallon V, Lang F.

Am J Physiol Renal Physiol. 2006 Dec;291(6):F1264-73. Epub 2006 Sep 26.PMID: 17003223 [PubMed - indexed for MEDLINE]Related articlesFree article

Use of a hanging-weight system for isolated renal artery occlusion during ischemic preconditioning in mice.

Grenz A, Eckle T, Zhang H, Huang DY, Wehrmann M, Köhle C, Unertl K, Osswald H, Eltzschig HK.

Am J Physiol Renal Physiol. 2007 Jan;292(1):F475-85. Epub 2006 Aug 15.PMID: 16912063 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of endothelin-1 on erythropoietin production in a rat model under normoxia and functional carbon monoxide-induced hypoxia.

Grenz A, Klein J, Köhle C, Freudenthaler S, Proksch B, Wu J, Wolf S, Osswald H, Gleiter CH.

Naunyn Schmiedebergs Arch Pharmacol. 2006 Aug;373(5):342-8. Epub 2006 Jul 29.PMID: 16896802 [PubMed - indexed for MEDLINE]Related articles

[Economic aspects of treatment with diuretics]

Luippold G, Osswald H.

Pharm Unserer Zeit. 2006;35(4):346-52. Review. German. No abstract available. PMID: 16886511 [PubMed - indexed for MEDLINE]Related articles

Adenosine and kidney function.

Vallon V, Mühlbauer B, Osswald H.

Physiol Rev. 2006 Jul;86(3):901-40. Review.PMID: 16816141 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of renal nerves and salt intake on erythropoietin secretion in rats following carbon monoxide exposure.

Gebhard C, Petroktistis F, Zhang H, Kammerer D, Köhle C, Klingel K, Albinus M, Gleiter CH, Osswald H, Grenz A.

J Pharmacol Exp Ther. 2006 Oct;319(1):111-6. Epub 2006 Jun 30.PMID: 16815869 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum- and glucocorticoid-inducible kinase 1 mediates salt sensitivity of glucose tolerance.

Boini KM, Hennige AM, Huang DY, Friedrich B, Palmada M, Boehmer C, Grahammer F, Artunc F, Ullrich S, Avram D, Osswald H, Wulff P, Kuhl D, Vallon V, Häring HU, Lang F.

Diabetes. 2006 Jul;55(7):2059-66.PMID: 16804076 [PubMed - indexed for MEDLINE]Related articlesFree article

Systematic evaluation of a novel model for cardiac ischemic preconditioning in mice.

Eckle T, Grenz A, Köhler D, Redel A, Falk M, Rolauffs B, Osswald H, Kehl F, Eltzschig HK.

Am J Physiol Heart Circ Physiol. 2006 Nov;291(5):H2533-40. Epub 2006 Jun 9.PMID: 16766632 [PubMed - indexed for MEDLINE]Related articlesFree article

SGK1-dependent cardiac CTGF formation and fibrosis following DOCA treatment.

Vallon V, Wyatt AW, Klingel K, Huang DY, Hussain A, Berchtold S, Friedrich B, Grahammer F, Belaiba RS, Görlach A, Wulff P, Daut J, Dalton ND, Ross J Jr, Flögel U, Schrader J, Osswald H, Kandolf R, Kuhl D, Lang F.

J Mol Med. 2006 May;84(5):396-404. Epub 2006 Apr 8.PMID: 16604333 [PubMed - indexed for MEDLINE]Related articles

Ecto-5'-nucleotidase (cd73)-dependent and -independent generation of adenosine participates in the mediation of tubuloglomerular feedback in vivo.

Huang DY, Vallon V, Zimmermann H, Koszalka P, Schrader J, Osswald H.

Am J Physiol Renal Physiol. 2006 Aug;291(2):F282-8. Epub 2006 Mar 8.PMID: 16525161 [PubMed - indexed for MEDLINE]Related articlesFree article

Sulindac induces specific degradation of the HPV oncoprotein E7 and causes growth arrest and apoptosis in cervical carcinoma cells.

Karl T, Seibert N, Stöhr M, Osswald H, Rösl F, Finzer P.

Cancer Lett. 2007 Jan 8;245(1-2):103-11. Epub 2006 Feb 20.PMID: 16488075 [PubMed - indexed for MEDLINE]Related articles

Theophylline improves early allograft function in rat kidney transplantation.

Grenz A, Baier D, Petroktistis F, Wehrmann M, Köhle C, Schenk M, Sessler M, Gleiter CH, Fandrich F, Osswald H.

J Pharmacol Exp Ther. 2006 May;317(2):473-9. Epub 2006 Jan 12.PMID: 16410406 [PubMed - indexed for MEDLINE]Related articlesFree article

Glibenclamide-induced apoptosis is specifically enhanced by expression of the sulfonylurea receptor isoform SUR1 but not by expression of SUR2B or the mutant SUR1(M1289T).

Hambrock A, de Oliveira Franz CB, Hiller S, Osswald H.

J Pharmacol Exp Ther. 2006 Mar;316(3):1031-7. Epub 2005 Nov 23.PMID: 16306272 [PubMed - indexed for MEDLINE]Related articlesFree article

Blunted hypertensive effect of combined fructose and high-salt diet in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase SGK1.

Huang DY, Boini KM, Friedrich B, Metzger M, Just L, Osswald H, Wulff P, Kuhl D, Vallon V, Lang F.

Am J Physiol Regul Integr Comp Physiol. 2006 Apr;290(4):R935-44. Epub 2005 Nov 10.PMID: 16284089 [PubMed - indexed for MEDLINE]Related articles

Studies of S-adenosylhomocysteine-hydrolase polymorphism in a Croatian population.

Kloor D, Fumic K, Attig S, Tete M, Osswald H, Baric I, Tomiuk J, Kömpf J.

J Hum Genet. 2006;51(1):21-4. Epub 2005 Nov 5.PMID: 16273424 [PubMed - indexed for MEDLINE]Related articles

SGK1 as a determinant of kidney function and salt intake in response to mineralocorticoid excess.

Vallon V, Huang DY, Grahammer F, Wyatt AW, Osswald H, Wulff P, Kuhl D, Lang F.

Am J Physiol Regul Integr Comp Physiol. 2005 Aug;289(2):R395-R401.PMID: 16014448 [PubMed - indexed for MEDLINE]Related articles

S-adenosylhomocysteine metabolism in different cell lines: effect of hypoxia and cell density.

Hermes M, von Hippel S, Osswald H, Kloor D.

Cell Physiol Biochem. 2005;15(5):233-44.PMID: 15956786 [PubMed - indexed for MEDLINE]Related articles

Effect of acute hyperhomocysteinemia on methylation potential of erythrocytes and on DNA methylation of lymphocytes in healthy male volunteers.

Fux R, Kloor D, Hermes M, Röck T, Proksch B, Grenz A, Delabar U, Bücheler R, Igel S, Mörike K, Gleiter CH, Osswald H.

Am J Physiol Renal Physiol. 2005 Oct;289(4):F786-92. Epub 2005 Apr 26.PMID: 15855656 [PubMed - indexed for MEDLINE]Related articlesFree article

Requirement of intact adenosine A1 receptors for the diuretic and natriuretic action of the methylxanthines theophylline and caffeine.

Rieg T, Steigele H, Schnermann J, Richter K, Osswald H, Vallon V.

J Pharmacol Exp Ther. 2005 Apr;313(1):403-9. Epub 2004 Dec 8.PMID: 15590766 [PubMed - indexed for MEDLINE]Related articlesFree article

Nephroprotection by theophylline in patients with cisplatin chemotherapy: a randomized, single-blinded, placebo-controlled trial.

Benoehr P, Krueth P, Bokemeyer C, Grenz A, Osswald H, Hartmann JT.

J Am Soc Nephrol. 2005 Feb;16(2):452-8. Epub 2004 Dec 8.PMID: 15590762 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of two amino acids in TM17 of Sulfonylurea receptor SUR1 on the binding of ATP-sensitive K+ channel modulators.

Hambrock A, Kayar T, Stumpp D, Osswald H.

Diabetes. 2004 Dec;53 Suppl 3:S128-34.PMID: 15561900 [PubMed - indexed for MEDLINE]Related articlesFree article

Kidney function in mice: thiobutabarbital versus alpha-chloralose anesthesia.

Rieg T, Richter K, Osswald H, Vallon V.

Naunyn Schmiedebergs Arch Pharmacol. 2004 Oct;370(4):320-3. Epub 2004 Sep 30.PMID: 15549274 [PubMed - indexed for MEDLINE]Related articles

Regulation of renal adenosine excretion in humans--role of sodium and fluid homeostasis.

Heyne N, Benöhr P, Mühlbauer B, Delabar U, Risler T, Osswald H.

Nephrol Dial Transplant. 2004 Nov;19(11):2737-41. Epub 2004 Sep 22.PMID: 15385638 [PubMed - indexed for MEDLINE]Related articlesFree article

S-Adenosylhomocysteine hydrolase as a target for intracellular adenosine action.

Kloor D, Osswald H.

Trends Pharmacol Sci. 2004 Jun;25(6):294-7. Review.PMID: 15165742 [PubMed - indexed for MEDLINE]Related articles

Influence of an altered methylation potential on mRNA methylation and gene expression in HepG2 cells.

Hermes M, Osswald H, Mattar J, Kloor D.

Exp Cell Res. 2004 Apr 1;294(2):325-34.PMID: 15023523 [PubMed - indexed for MEDLINE]Related articles

Dopamine D3 receptor mRNA and renal response to D3 receptor activation in spontaneously hypertensive rats.

Luippold G, Piesch C, Osswald H, Mühlbauer B.

Hypertens Res. 2003 Oct;26(10):855-61.PMID: 14621190 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenosine binding sites at S-adenosylhomocysteine hydrolase are controlled by the NAD+/NADH ratio of the enzyme.

Kloor D, Lüdtke A, Stoeva S, Osswald H.

Biochem Pharmacol. 2003 Dec 1;66(11):2117-23.PMID: 14609736 [PubMed - indexed for MEDLINE]Related articles

Do alterations of endogenous angiotensin II levels regulate erythropoietin production in humans?

Freudenthaler S, Benöhr P, Grenz A, Selzer T, Schmidt T, Mörike K, Osswald H, Gleiter CH.

Br J Clin Pharmacol. 2003 Oct;56(4):378-87.PMID: 12968982 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of the renin-angiotensin system in the compensation of quinpirole-induced blood pressure decrease.

Luippold G, Max A, Albinus M, Osswald H, Mühlbauer B.

Naunyn Schmiedebergs Arch Pharmacol. 2003 May;367(5):427-33. Epub 2003 Apr 23.PMID: 12709781 [PubMed - indexed for MEDLINE]Related articles

Differential renal response to Nomega-nitro-L-arginine methyl ester and L-arginine in rats with hypertensive or diabetic nephropathy.

Erley CM, Heyne N, Friedrich B, Schmidt T, Strobel U, Wehrmann M, Osswald H.

J Cardiovasc Pharmacol. 2002 Nov;40(5):780-8.PMID: 12409987 [PubMed - indexed for MEDLINE]Related articles

The preventive effect of sodium pentosan polysulfate against renal stone formation in hyperoxaluric rats.

Nakatani T, Ishii K, Yoneda Y, Kamikawa S, Kanazawa T, Sugimoto T, Osswald H.

Urol Res. 2002 Oct;30(5):329-35. Epub 2002 Aug 15.PMID: 12389123 [PubMed - indexed for MEDLINE]Related articles

Characterization of the cAMP binding site of purified S-adenosyl-homocysteine hydrolase from bovine kidney.

Kloor D, Danielyan L, Osswald H.

Biochem Pharmacol. 2002 Oct 15;64(8):1201-6.PMID: 12234600 [PubMed - indexed for MEDLINE]Related articles

Tissue levels of S-adenosylhomocysteine in the rat kidney: effects of ischemia and homocysteine.

Kloor D, Delabar U, Mühlbauer B, Luippold G, Osswald H.

Biochem Pharmacol. 2002 Feb 15;63(4):809-15.PMID: 11992651 [PubMed - indexed for MEDLINE]Related articles