PubMed

Inhibition of Transforming Growth Factor (TGF)-{beta} Signaling Induces Left Ventricular Dilation and Dysfunction in the Pressure Overloaded Heart.

Lucas JA, Zhang Y, Li P, Gong K, Miller AP, Hassan E, Hage F, Xing D, Wells B, Oparil S, Chen YF.

Am J Physiol Heart Circ Physiol. 2009 Nov 20. [Epub ahead of print]PMID: 19933419 [PubMed - as supplied by publisher]

Reduction of blood pressure in patients with treatment-resistant hypertension.

Acelajado MC, Calhoun DA, Oparil S.

Expert Opin Pharmacother. 2009 Nov 19. [Epub ahead of print]PMID: 19925047 [PubMed - as supplied by publisher]Related articles

Prehypertension: epidemiology, consequences and treatment.

Pimenta E, Oparil S; Medscape.

Nat Rev Nephrol. 2009 Nov 17. [Epub ahead of print]PMID: 19918256 [PubMed - as supplied by publisher]Related articles

Safety and tolerability of fixed-dose irbesartan/hydrochlorothiazide for rapid control of severe hypertension.

Neutel JM, Franklin SS, Bhaumik A, Lapuerta P, Oparil S.

Clin Exp Hypertens. 2009 Oct;31(7):572-84.PMID: 19886855 [PubMed - in process]Related articles

Hypertension in the elderly.

Acelajado MC, Oparil S.

Clin Geriatr Med. 2009 Aug;25(3):391-412.PMID: 19765488 [PubMed - in process]Related articles

Efficacy and safety of long-term treatment with the combination of amlodipine besylate and olmesartan medoxomil in patients with hypertension.

Chrysant SG, Oparil S, Melino M, Karki S, Lee J, Heyrman R.

J Clin Hypertens (Greenwich). 2009 Sep;11(9):475-82.PMID: 19751459 [PubMed - in process]Related articles

Subgroup Analyses of an Efficacy and Safety Study of Concomitant Administration of Amlodipine Besylate and Olmesartan Medoxomil: Evaluation by Baseline Hypertension Stage and Prior Antihypertensive Medication Use.

Oparil S, Lee J, Karki S, Melino M.

J Cardiovasc Pharmacol. 2009 Aug 28. [Epub ahead of print]PMID: 19730391 [PubMed - as supplied by publisher]Related articles

Role of aliskiren in cardio-renal protection and use in hypertensives with multiple risk factors.

Pimenta E, Oparil S.

Ther Clin Risk Manag. 2009 Jun;5(3):459-64. Epub 2009 Jun 22.PMID: 19707255 [PubMed - in process]Related articlesFree article

A true champion of Hungarian kidney research and nephrology education--tribute to László Rosivall.

Peti-Peterdi J, Navar LG, Darwin Bell P, Casellas D, Carmines PK, Inscho EW, Oparil S.

Acta Physiol Hung. 2009 Sep;96(3):375-82.PMID: 19706379 [PubMed - indexed for MEDLINE]Related articles

EXCEED: Exforge(R) - intensive control of hypertension to evaluate efficacy in diastolic dysfunction: study rationale,design, and participant characteristics.

Hassanein A, Desai A, Verma A, Oparil S, Izzo J, Rocha R, Hilkert R, Seifu Y, Pitt B, Solomon SD.

Ther Adv Cardiovasc Dis. 2009 Jul 28. [Epub ahead of print]PMID: 19638366 [PubMed - as supplied by publisher]Related articles

Effects of dietary sodium reduction on blood pressure in subjects with resistant hypertension: results from a randomized trial.

Pimenta E, Gaddam KK, Oparil S, Aban I, Husain S, Dell'Italia LJ, Calhoun DA.

Hypertension. 2009 Sep;54(3):475-81. Epub 2009 Jul 20.PMID: 19620517 [PubMed - indexed for MEDLINE]Related articlesFree article

ASH Position Paper: Dietary approaches to lower blood pressure.

Appel LJ; American Society of Hypertension Writing Group, Giles TD, Black HR, Izzo JL Jr, Materson BJ, Oparil S, Weber MA.

J Clin Hypertens (Greenwich). 2009 Jul;11(7):358-68.PMID: 19583632 [PubMed - indexed for MEDLINE]Related articles

Facts and fallacies of blood pressure control in recent trials: implications in the management of patients with hypertension.

Zanchetti A, Mancia G, Black HR, Oparil S, Waeber B, Schmieder RE, Bakris GL, Messerli FH, Kjeldsen SE, Ruilope LM.

J Hypertens. 2009 Apr;27(4):673-9. Review.PMID: 19516168 [PubMed - indexed for MEDLINE]Related articles

Does GISSI-AF change the concept of using RAS inhibitors in the primary prevention of atrial fibrillation in hypertensive patients?

Kjeldsen SE, Oparil S, Hedner T, Narkiewicz K.

Blood Press. 2009 May 29:1-2. [Epub ahead of print] No abstract available. PMID: 19484619 [PubMed - as supplied by publisher]Related articles

Role of aliskiren in cardio-renal protection and use in hypertensives with multiple risk factors.

Pimenta E, Oparil S.

Vasc Health Risk Manag. 2009;5(1):453-63. Review.PMID: 19475781 [PubMed - indexed for MEDLINE]Related articlesFree article

ALLHAT findings revisited in the context of subsequent analyses, other trials, and meta-analyses.

Wright JT Jr, Probstfield JL, Cushman WC, Pressel SL, Cutler JA, Davis BR, Einhorn PT, Rahman M, Whelton PK, Ford CE, Haywood LJ, Margolis KL, Oparil S, Black HR, Alderman MH; ALLHAT Collaborative Research Group.

Arch Intern Med. 2009 May 11;169(9):832-42.PMID: 19433694 [PubMed - indexed for MEDLINE]Related articles

Angiotensin receptor blocker and dihydropyridine calcium channel blocker combinations: an emerging strategy in hypertension therapy.

Oparil S, Weber M.

Postgrad Med. 2009 Mar;121(2):25-39. Review.PMID: 19332960 [PubMed - indexed for MEDLINE]Related articles

Hormone therapy of premature ovarian failure: the case for "natural" estrogen.

Oparil S.

Hypertension. 2009 May;53(5):745-6. Epub 2009 Mar 30. No abstract available. PMID: 19332657 [PubMed - indexed for MEDLINE]Related articles

Loss of Thy-1 inhibits alveolar development in the newborn mouse lung.

Nicola T, Hagood JS, James ML, Macewen MW, Williams TA, Hewitt MM, Schwiebert L, Bulger A, Oparil S, Chen YF, Ambalavanan N.

Am J Physiol Lung Cell Mol Physiol. 2009 May;296(5):L738-50. Epub 2009 Mar 6.PMID: 19270178 [PubMed - indexed for MEDLINE]Related articles

Effects of losartan compared with atenolol on lipids in patients with hypertension and left ventricular hypertrophy: the Losartan Intervention For Endpoint reduction in hypertension study.

Olsen MH, Wachtell K, Beevers G, Dahlöf B, de Simone G, Devereux RB, de Faire U, Fyhrquist F, Ibsen H, Kjeldsen SE, Lederballe-Pedersen O, Lindholm LH, Lyle PA, Nieminen MS, Omvik P, Oparil S, Wedel H.

J Hypertens. 2009 Mar;27(3):567-74.PMID: 19262226 [PubMed - indexed for MEDLINE]Related articles

Sleep apnea, aldosterone, and resistant hypertension.

Pimenta E, Calhoun DA, Oparil S.

Prog Cardiovasc Dis. 2009 Mar-Apr;51(5):371-80. Review.PMID: 19249443 [PubMed - indexed for MEDLINE]Related articles

Estrogen and mechanisms of vascular protection.

Xing D, Nozell S, Chen YF, Hage F, Oparil S.

Arterioscler Thromb Vasc Biol. 2009 Mar;29(3):289-95. Epub 2009 Feb 16. Review.PMID: 19221203 [PubMed - indexed for MEDLINE]Related articles

More focus on therapeutic targets and improved tolerability in hypertension.

Hedner T, Kjeldsen SE, Narkiewicz K, Oparil S.

Blood Press Suppl. 2008 Dec;2:3-4. No abstract available. PMID: 19203018 [PubMed - indexed for MEDLINE]Related articles

ONTARGET, TRANSCEND and PROFESS--clarifying, confusing or misleading?

Oparil S, Kjeldsen SE, Hedner T, Narkiewicz K.

Blood Press. 2009;18(1-2):4-6. No abstract available. PMID: 19191085 [PubMed - indexed for MEDLINE]Related articles

Results of an olmesartan medoxomil-based treatment regimen in hypertensive patients.

Oparil S, Chrysant SG, Kereiakes D, Xu J, Chavanu KJ, Waverczak W, Dubiel R.

J Clin Hypertens (Greenwich). 2008 Dec;10(12):911-21.PMID: 19120717 [PubMed - indexed for MEDLINE]Related articles

Benefits of hypertension management in diabetes: an opportunity not to be missed.

Narkiewicz K, Oparil S, Kjeldsen S, Hedner T.

Blood Press. 2008;17(5-6):248-9. No abstract available. PMID: 19085534 [PubMed - indexed for MEDLINE]Related articles

Prognostic importance of hemoglobin in hypertensive patients with electrocardiographic left ventricular hypertrophy: the Losartan Intervention For End point reduction in hypertension (LIFE) study.

Olsen MH, Wachtell K, Beevers G, Dahlöf B, Devereux RB, de Faire U, Fyhrquist F, Ibsen H, Kjeldsen SE, Lederballe-Pedersen O, Lindholm LH, Narayan P, Nieminen MS, Omvik P, Oparil S, Wedel H.

Am Heart J. 2009 Jan;157(1):177-84. Epub 2008 Oct 17.PMID: 19081416 [PubMed - indexed for MEDLINE]Related articles

Aliskiren and valsartan in stage 2 hypertension: subgroup analysis of a randomized, double-blind study.

Yarows SA, Oparil S, Patel S, Fang H, Zhang J.

Adv Ther. 2008 Dec;25(12):1288-302.PMID: 19066757 [PubMed - in process]Related articles

Combining RAAS and calcium channel blockade: ACCOMPLISH in perspective.

Kjeldsen SE, Weber M, Oparil S, Jamerson KA.

Blood Press. 2008;17(5-6):260-9.PMID: 19061055 [PubMed - indexed for MEDLINE]Related articles

Protein O-GlcNAcylation: a new signaling paradigm for the cardiovascular system.

Laczy B, Hill BG, Wang K, Paterson AJ, White CR, Xing D, Chen YF, Darley-Usmar V, Oparil S, Chatham JC.

Am J Physiol Heart Circ Physiol. 2009 Jan;296(1):H13-28. Epub 2008 Nov 21.PMID: 19028792 [PubMed - indexed for MEDLINE]Related articles

Management of older hypertensive patients.

Hedner T, Kjeldsen S, Oparil S, Narkiewics K.

Blood Press. 2008;17(4):184-5. No abstract available. PMID: 18932064 [PubMed - indexed for MEDLINE]Related articles

Renin inhibitors: novel agents for renoprotection or a better angiotensin receptor blocker for blood pressure lowering?

Pimenta E, Oparil S.

Cardiol Clin. 2008 Nov;26(4):527-35. Review.PMID: 18929229 [PubMed - indexed for MEDLINE]Related articles

Should we prefer different drugs to treat hypertension in older and younger adults? Practical implications of clinical trials: American perspective.

Pimenta E, Oparil S.

Pol Arch Med Wewn. 2008 Sep;118(9):508-12. Review.PMID: 18846986 [PubMed - indexed for MEDLINE]Related articlesFree article

Fixed combinations in the management of hypertension: patient perspectives and rationale for development and utility of the olmesartan-amlodipine combination.

Pimenta E, Oparil S.

Vasc Health Risk Manag. 2008;4(3):653-64. Review.PMID: 18827915 [PubMed - indexed for MEDLINE]Related articlesFree article

Beyond brachial pressure effect.

Pimenta E, Oparil S.

Curr Hypertens Rep. 2008 Jun;10(3):213-5. No abstract available. PMID: 18765092 [PubMed]Related articles

Achieving better blood pressure control.

Hedner T, Oparil S, Narkiewicz K, Kjeldsen SE.

Blood Press Suppl. 2008 Jun;1:3-4. No abstract available. PMID: 18705529 [PubMed - indexed for MEDLINE]Related articles

Renin inhibition: should it supplant ACE inhibitors and ARBS in high risk patients?

Gaddam KK, Oparil S.

Curr Opin Nephrol Hypertens. 2008 Sep;17(5):484-90. Review.PMID: 18695389 [PubMed - indexed for MEDLINE]Related articles

More is less? Optimal combination therapy for adequate blood pressure lowering in hypertension.

Kjeldsen SE, Hedner T, Narkiewicz K, Oparil S.

Blood Press. 2008;17(3):132-3. No abstract available. PMID: 18665471 [PubMed - indexed for MEDLINE]Related articles

Marked regional left ventricular heterogeneity in hypertensive left ventricular hypertrophy patients: a losartan intervention for endpoint reduction in hypertension (LIFE) cardiovascular magnetic resonance and echocardiographic substudy.

Biederman RW, Doyle M, Young AA, Devereux RB, Kortright E, Perry G, Bella JN, Oparil S, Calhoun D, Pohost GM, Dell'Italia LJ.

Hypertension. 2008 Aug;52(2):279-86. Epub 2008 Jul 7.PMID: 18606908 [PubMed - indexed for MEDLINE]Related articlesFree article

A stunning day in hypertension research - Results of ONTARGET, ACCOMPLISH and HYVET.

Kjeldsen SE, Oparil S, Narkiewicz K, Hedner T.

Blood Press. 2008;17(2):68-9. No abstract available. PMID: 18568694 [PubMed - indexed for MEDLINE]Related articles

Urgent need to address quality control issues of out-of-office blood pressure measurement and patient risk assessment.

Hedner T, Kjeldsen SE, Narkiewicz K, Oparil S.

Blood Press. 2008;17(1):5-6. No abstract available. PMID: 18568686 [PubMed - indexed for MEDLINE]Related articles

Characterization of resistant hypertension: association between resistant hypertension, aldosterone, and persistent intravascular volume expansion.

Gaddam KK, Nishizaka MK, Pratt-Ubunama MN, Pimenta E, Aban I, Oparil S, Calhoun DA.

Arch Intern Med. 2008 Jun 9;168(11):1159-64.PMID: 18541823 [PubMed - indexed for MEDLINE]Related articlesFree article

Thiazide-induced dysglycemia: call for research from a working group from the national heart, lung, and blood institute.

Carter BL, Einhorn PT, Brands M, He J, Cutler JA, Whelton PK, Bakris GL, Brancati FL, Cushman WC, Oparil S, Wright JT Jr; Working Group from the National Heart, Lung, and Blood Institute.

Hypertension. 2008 Jul;52(1):30-6. Epub 2008 May 26. Review. No abstract available. PMID: 18504319 [PubMed - indexed for MEDLINE]Related articlesFree article

Transforming growth factor-beta signaling mediates hypoxia-induced pulmonary arterial remodeling and inhibition of alveolar development in newborn mouse lung.

Ambalavanan N, Nicola T, Hagood J, Bulger A, Serra R, Murphy-Ullrich J, Oparil S, Chen YF.

Am J Physiol Lung Cell Mol Physiol. 2008 Jul;295(1):L86-95. Epub 2008 May 16.PMID: 18487357 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of oxygen availability in CFTR expression and function.

Guimbellot JS, Fortenberry JA, Siegal GP, Moore B, Wen H, Venglarik C, Chen YF, Oparil S, Sorscher EJ, Hong JS.

Am J Respir Cell Mol Biol. 2008 Nov;39(5):514-21. Epub 2008 May 12.PMID: 18474670 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased protein O-GlcNAc modification inhibits inflammatory and neointimal responses to acute endoluminal arterial injury.

Xing D, Feng W, Nöt LG, Miller AP, Zhang Y, Chen YF, Majid-Hassan E, Chatham JC, Oparil S.

Am J Physiol Heart Circ Physiol. 2008 Jul;295(1):H335-42. Epub 2008 May 9.PMID: 18469144 [PubMed - indexed for MEDLINE]Related articlesFree article

A double-blind, randomized study evaluating losartan potassium monotherapy or in combination with hydrochlorothiazide versus placebo in obese patients with hypertension.

Oparil S, Abate N, Chen E, Creager MA, Galet V, Jia G, Julius S, Lerman A, Lyle PA, Pool J, Tershakovec AM.

Curr Med Res Opin. 2008 Apr;24(4):1101-14. Epub 2008 Mar 6.PMID: 18328120 [PubMed - indexed for MEDLINE]Related articles

Mechanisms and treatment of resistant hypertension.

Pimenta E, Gaddam KK, Oparil S.

J Clin Hypertens (Greenwich). 2008 Mar;10(3):239-44.PMID: 18326968 [PubMed - indexed for MEDLINE]Related articles

Hypertension: what it is; what it isn't; how to think about it, to prevent it, and to manage it. Interview by George D. Lundberg.

Oparil S.

MedGenMed. 2007 Dec 12;9(4):56. No abstract available. PMID: 18311405 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of losartan in women with hypertension and left ventricular hypertrophy: results from the Losartan Intervention for Endpoint Reduction in Hypertension Study.

Os I, Franco V, Kjeldsen SE, Manhem K, Devereux RB, Gerdts E, Hille DA, Lyle PA, Okin PM, Dahlöf B, Oparil S.

Hypertension. 2008 Apr;51(4):1103-8. Epub 2008 Feb 7.PMID: 18259029 [PubMed - indexed for MEDLINE]Related articlesFree article