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    Results: 1 to 50 of 227

    1.

    Identification of novel gene amplifications in breast cancer and coexistence of gene amplification with an activating mutation of PIK3CA.

    Kadota M, Sato M, Duncan B, Ooshima A, Yang HH, Diaz-Meyer N, Gere S, Kageyama S, Fukuoka J, Nagata T, Tsukada K, Dunn BK, Wakefield LM, Lee MP.

    Cancer Res. 2009 Sep 15;69(18):7357-65. Epub 2009 Aug 25.PMID: 19706770 [PubMed - indexed for MEDLINE]Related articles

    2.

    Trps1 regulates proliferation and apoptosis of chondrocytes through Stat3 signaling.

    Suemoto H, Muragaki Y, Nishioka K, Sato M, Ooshima A, Itoh S, Hatamura I, Ozaki M, Braun A, Gustafsson E, Fässler R.

    Dev Biol. 2007 Dec 15;312(2):572-81. Epub 2007 Oct 10.PMID: 17997399 [PubMed - indexed for MEDLINE]Related articles

    3.

    Transforming growth factor-beta can suppress tumorigenesis through effects on the putative cancer stem or early progenitor cell and committed progeny in a breast cancer xenograft model.

    Tang B, Yoo N, Vu M, Mamura M, Nam JS, Ooshima A, Du Z, Desprez PY, Anver MR, Michalowska AM, Shih J, Parks WT, Wakefield LM.

    Cancer Res. 2007 Sep 15;67(18):8643-52.PMID: 17875704 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Increased type III and V collagen expression in human corpora lutea in early pregnancy.

    Iwahashi M, Muragaki Y, Ooshima A, Umesaki N.

    Fertil Steril. 2007 Jan;87(1):178-81. Epub 2006 Nov 21.PMID: 17118369 [PubMed - indexed for MEDLINE]Related articles

    6.

    Possible role of preproghrelin gene polymorphisms in susceptibility to bulimia nervosa.

    Ando T, Komaki G, Naruo T, Okabe K, Takii M, Kawai K, Konjiki F, Takei M, Oka T, Takeuchi K, Masuda A, Ozaki N, Suematsu H, Denda K, Kurokawa N, Itakura K, Yamaguchi C, Kono M, Suzuki T, Nakai Y, Nishizono-Maher A, Koide M, Murakami K, Nagamine K, Tomita Y, Ookuma K, Tomita K, Tonai E, Ooshima A, Ishikawa T, Ichimaru Y.

    Am J Med Genet B Neuropsychiatr Genet. 2006 Dec 5;141B(8):929-34.PMID: 16921495 [PubMed - indexed for MEDLINE]Related articles

    7.

    Gene transfer of Smad7 modulates injury-induced conjunctival wound healing in mice.

    Yamanaka O, Ikeda K, Saika S, Miyazaki K, Ooshima A, Ohnishi Y.

    Mol Vis. 2006 Aug 1;12:841-51.PMID: 16902401 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    A new model of anterior subcapsular cataract: involvement of TGFbeta/Smad signaling.

    Shirai K, Saika S, Tanaka T, Okada Y, Flanders KC, Ooshima A, Ohnishi Y.

    Mol Vis. 2006 Jun 14;12:681-91.PMID: 16807527 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Interleukin-7 modulates extracellular matrix production and TGF-beta signaling in cultured human subconjunctival fibroblasts.

    Yamanaka O, Saika S, Ikeda K, Miyazaki K, Ohnishi Y, Ooshima A.

    Curr Eye Res. 2006 Jun;31(6):491-9.PMID: 16769608 [PubMed - indexed for MEDLINE]Related articles

    10.

    Loss of tumor necrosis factor alpha potentiates transforming growth factor beta-mediated pathogenic tissue response during wound healing.

    Saika S, Ikeda K, Yamanaka O, Flanders KC, Okada Y, Miyamoto T, Kitano A, Ooshima A, Nakajima Y, Ohnishi Y, Kao WW.

    Am J Pathol. 2006 Jun;168(6):1848-60.PMID: 16723700 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Combination gene therapy of HGF and truncated type II TGF-beta receptor for rat liver cirrhosis after partial hepatectomy.

    Ozawa S, Uchiyama K, Nakamori M, Ueda K, Iwahashi M, Ueno H, Muragaki Y, Ooshima A, Yamaue H.

    Surgery. 2006 Apr;139(4):563-73.PMID: 16627068 [PubMed - indexed for MEDLINE]Related articles

    12.

    Immunohistochemical analysis of collagen expression in human corpora lutea during the menstrual cycle and early pregnancy.

    Iwahashi M, Muragaki Y, Ooshima A, Umesaki N.

    Fertil Steril. 2006 Apr;85 Suppl 1:1093-6.PMID: 16616079 [PubMed - indexed for MEDLINE]Related articles

    13.

    Up-regulation of Cbfa1 and Pit-1 in calcified artery of uraemic rats with severe hyperphosphataemia and secondary hyperparathyroidism.

    Mizobuchi M, Ogata H, Hatamura I, Koiwa F, Saji F, Shiizaki K, Negi S, Kinugasa E, Ooshima A, Koshikawa S, Akizawa T.

    Nephrol Dial Transplant. 2006 Apr;21(4):911-6. Epub 2005 Dec 29.PMID: 16384827 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis.

    Roberts AB, Tian F, Byfield SD, Stuelten C, Ooshima A, Saika S, Flanders KC.

    Cytokine Growth Factor Rev. 2006 Feb-Apr;17(1-2):19-27. Epub 2005 Nov 11. Review.PMID: 16290023 [PubMed - indexed for MEDLINE]Related articles

    15.

    Upregulation of transforming growth factor-beta1 and vascular endothelial growth factor in cultured keloid fibroblasts: relevance to angiogenic activity.

    Fujiwara M, Muragaki Y, Ooshima A.

    Arch Dermatol Res. 2005 Oct;297(4):161-9. Epub 2005 Oct 26.PMID: 16184401 [PubMed - indexed for MEDLINE]Related articles

    16.

    Adenoviral gene transfer of BMP-7, Id2, or Id3 suppresses injury-induced epithelial-to-mesenchymal transition of lens epithelium in mice.

    Saika S, Ikeda K, Yamanaka O, Flanders KC, Ohnishi Y, Nakajima Y, Muragaki Y, Ooshima A.

    Am J Physiol Cell Physiol. 2006 Jan;290(1):C282-9. Epub 2005 Aug 24.PMID: 16120655 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Keloid-derived fibroblasts show increased secretion of factors involved in collagen turnover and depend on matrix metalloproteinase for migration.

    Fujiwara M, Muragaki Y, Ooshima A.

    Br J Dermatol. 2005 Aug;153(2):295-300.PMID: 16086739 [PubMed - indexed for MEDLINE]Related articles

    18.

    Inhibition of p38MAP kinase suppresses fibrotic reaction of retinal pigment epithelial cells.

    Saika S, Yamanaka O, Ikeda K, Kim-Mitsuyama S, Flanders KC, Yoo J, Roberts AB, Nishikawa-Ishida I, Ohnishi Y, Muragaki Y, Ooshima A.

    Lab Invest. 2005 Jul;85(7):838-50.PMID: 15924151 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Expression of Smad7 in mouse eyes accelerates healing of corneal tissue after exposure to alkali.

    Saika S, Ikeda K, Yamanaka O, Miyamoto T, Ohnishi Y, Sato M, Muragaki Y, Ooshima A, Nakajima Y, Kao WW, Flanders KC, Roberts AB.

    Am J Pathol. 2005 May;166(5):1405-18.PMID: 15855641 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Therapeutic effect of topical administration of SN50, an inhibitor of nuclear factor-kappaB, in treatment of corneal alkali burns in mice.

    Saika S, Miyamoto T, Yamanaka O, Kato T, Ohnishi Y, Flanders KC, Ikeda K, Nakajima Y, Kao WW, Sato M, Muragaki Y, Ooshima A.

    Am J Pathol. 2005 May;166(5):1393-403.PMID: 15855640 [PubMed - indexed for MEDLINE]Related articlesFree article

    21.

    Therapeutic effects of adenoviral gene transfer of bone morphogenic protein-7 on a corneal alkali injury model in mice.

    Saika S, Ikeda K, Yamanaka O, Flanders KC, Nakajima Y, Miyamoto T, Ohnishi Y, Kao WW, Muragaki Y, Ooshima A.

    Lab Invest. 2005 Apr;85(4):474-86.PMID: 15696184 [PubMed - indexed for MEDLINE]Related articlesFree article

    22.

    Biochemical and cellular effects of direct maxacalcitol injection into parathyroid gland in uremic rats.

    Shiizaki K, Negi S, Hatamura I, Sakaguchi T, Saji F, Kunimoto K, Mizobuchi M, Imazeki I, Ooshima A, Akizawa T.

    J Am Soc Nephrol. 2005 Jan;16(1):97-108. Epub 2004 Dec 1.PMID: 15574509 [PubMed - indexed for MEDLINE]Related articlesFree article

    23.

    Accumulation of thrombospondin-1 in post-operative capsular fibrosis and its down-regulation in lens cells during lens fiber formation.

    Saika S, Miyamoto T, Ishida I, Barbour WK, Ohnishi Y, Ooshima A.

    Exp Eye Res. 2004 Aug;79(2):147-56.PMID: 15325561 [PubMed - indexed for MEDLINE]Related articles

    24.

    Sonic hedgehog expression and role in healing corneal epithelium.

    Saika S, Muragaki Y, Okada Y, Miyamoto T, Ohnishi Y, Ooshima A, Kao WW.

    Invest Ophthalmol Vis Sci. 2004 Aug;45(8):2577-85.PMID: 15277480 [PubMed - indexed for MEDLINE]Related articlesFree article

    25.

    Smad3 is required for dedifferentiation of retinal pigment epithelium following retinal detachment in mice.

    Saika S, Kono-Saika S, Tanaka T, Yamanaka O, Ohnishi Y, Sato M, Muragaki Y, Ooshima A, Yoo J, Flanders KC, Roberts AB.

    Lab Invest. 2004 Oct;84(10):1245-58.PMID: 15273699 [PubMed - indexed for MEDLINE]Related articlesFree article

    26.

    Fibroblast growth factor 2: roles of regulation of lens cell proliferation and epithelial-mesenchymal transition in response to injury.

    Tanaka T, Saika S, Ohnishi Y, Ooshima A, McAvoy JW, Liu CY, Azhar M, Doetschman T, Kao WW.

    Mol Vis. 2004 Jul 15;10:462-7.PMID: 15273655 [PubMed - indexed for MEDLINE]Related articlesFree article

    27.

    Transient adenoviral gene transfer of Smad7 prevents injury-induced epithelial-mesenchymal transition of lens epithelium in mice.

    Saika S, Ikeda K, Yamanaka O, Sato M, Muragaki Y, Ohnishi Y, Ooshima A, Nakajima Y, Namikawa K, Kiyama H, Flanders KC, Roberts AB.

    Lab Invest. 2004 Oct;84(10):1259-70.PMID: 15258599 [PubMed - indexed for MEDLINE]Related articlesFree article

    28.

    Protein expression pattern of collagen type XV in mouse cornea.

    Saika S, Okada Y, Miyamoto T, Yamanaka O, Ohnishi Y, Yamanaka A, Ooshima A.

    Graefes Arch Clin Exp Ophthalmol. 2004 May;242(5):432-6. Epub 2004 Jan 29.PMID: 14752666 [PubMed - indexed for MEDLINE]Related articles

    29.

    Smad3 signaling is required for epithelial-mesenchymal transition of lens epithelium after injury.

    Saika S, Kono-Saika S, Ohnishi Y, Sato M, Muragaki Y, Ooshima A, Flanders KC, Yoo J, Anzano M, Liu CY, Kao WW, Roberts AB.

    Am J Pathol. 2004 Feb;164(2):651-63.PMID: 14742269 [PubMed - indexed for MEDLINE]Related articlesFree article

    30.

    Role of p38 MAP kinase in regulation of cell migration and proliferation in healing corneal epithelium.

    Saika S, Okada Y, Miyamoto T, Yamanaka O, Ohnishi Y, Ooshima A, Liu CY, Weng D, Kao WW.

    Invest Ophthalmol Vis Sci. 2004 Jan;45(1):100-9.PMID: 14691160 [PubMed - indexed for MEDLINE]Related articlesFree article

    31.

    Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction.

    Sato M, Muragaki Y, Saika S, Roberts AB, Ooshima A.

    J Clin Invest. 2003 Nov;112(10):1486-94.PMID: 14617750 [PubMed - indexed for MEDLINE]Related articlesFree article

    32.

    Percutaneous maxacalcitol injection therapy regresses hyperplasia of parathyroid and induces apoptosis in uremia.

    Shiizaki K, Hatamura I, Negi S, Narukawa N, Mizobuchi M, Sakaguchi T, Ooshima A, Akizawa T.

    Kidney Int. 2003 Sep;64(3):992-1003.PMID: 12911549 [PubMed - indexed for MEDLINE]Related articles

    33.

    Decreased type I collagen expression in human uterine cervix during pregnancy.

    Iwahashi M, Muragaki Y, Ooshima A, Umesaki N.

    J Clin Endocrinol Metab. 2003 May;88(5):2231-5.PMID: 12727979 [PubMed - indexed for MEDLINE]Related articlesFree article

    34.

    Response of lens epithelial cells to injury: role of lumican in epithelial-mesenchymal transition.

    Saika S, Miyamoto T, Tanaka S, Tanaka T, Ishida I, Ohnishi Y, Ooshima A, Ishiwata T, Asano G, Chikama T, Shiraishi A, Liu CY, Kao CW, Kao WW.

    Invest Ophthalmol Vis Sci. 2003 May;44(5):2094-102.PMID: 12714648 [PubMed - indexed for MEDLINE]Related articlesFree article

    35.

    Osteopontin: a component of matrix in capsular opacification and subcapsular cataract.

    Saika S, Miyamoto T, Ishida I, Ohnishi Y, Ooshima A.

    Invest Ophthalmol Vis Sci. 2003 Apr;44(4):1622-8.PMID: 12657601 [PubMed - indexed for MEDLINE]Related articlesFree article

    36.

    Effects of interferon-gamma on human subconjunctival fibroblasts in the presence of TGFbeta1: reversal of TGFbeta-stimulated collagen production.

    Yamanaka O, Saika S, Okada Y, Ooshima A, Ohnishi Y.

    Graefes Arch Clin Exp Ophthalmol. 2003 Feb;241(2):116-24. Epub 2002 Dec 24.PMID: 12605266 [PubMed - indexed for MEDLINE]Related articles

    37.

    TGFbeta-Smad signalling in postoperative human lens epithelial cells.

    Saika S, Miyamoto T, Ishida I, Shirai K, Ohnishi Y, Ooshima A, McAvoy JW.

    Br J Ophthalmol. 2002 Dec;86(12):1428-33.PMID: 12446380 [PubMed - indexed for MEDLINE]Related articlesFree article

    38.

    Lens epithelial cell death after cataract surgery.

    Saika S, Miyamoto T, Ishida I, Ohnishi Y, Ooshima A.

    J Cataract Refract Surg. 2002 Aug;28(8):1452-6.PMID: 12160819 [PubMed - indexed for MEDLINE]Related articles

    39.

    Cellular fibronectin, but not collagens, disappears in the central posterior capsules during healing after lens extraction and IOL implantation in rabbits.

    Tanaka S, Saika S, Ohmi S, Miyamoto T, Ishida I, Okada Y, Yamanaka O, Ohnishi Y, Ooshima A.

    Jpn J Ophthalmol. 2002 Mar-Apr;46(2):147-52.PMID: 12062219 [PubMed - indexed for MEDLINE]Related articles

    40.

    Collagens XII and XIV (FACITs) in capsular opacification and in cultured lens epithelial cells.

    Saika S, Miyamoto T, Tanaka T, Ishida I, Ohnishi Y, Ooshima A.

    Curr Eye Res. 2001 Dec;23(6):463-8.PMID: 12045897 [PubMed - indexed for MEDLINE]Related articles

    41.

    Epithelial repair: roles of extracellular matrix.

    Saika S, Ohnishi Y, Ooshima A, Liu CY, Kao WW.

    Cornea. 2002 Mar;21(2 Suppl 1):S23-9. Review.PMID: 11995806 [PubMed - indexed for MEDLINE]Related articles

    42.

    Histopathology of anterior lens capsules in vitrectomized eyes with tamponade by silicone oil.

    Saika S, Miyamoto T, Tanaka T, Ohnishi Y, Ooshima A, Kimura W.

    J Cataract Refract Surg. 2002 Feb;28(2):376-8.PMID: 11821226 [PubMed - indexed for MEDLINE]Related articles

    43.

    Latent TGFbeta binding protein-1 and fibrillin-1 in human capsular opacification and in cultured lens epithelial cells.

    Saika S, Miyamoto T, Tanaka T, Ishida I, Ohnishi Y, Ooshima A.

    Br J Ophthalmol. 2001 Nov;85(11):1362-6.PMID: 11673307 [PubMed - indexed for MEDLINE]Related articlesFree article

    44.

    Lens epithelial cell regeneration of a capsule-like structure during postoperative healing in rabbits.

    Saika S, Miyamoto T, Ishida I, Okada Y, Ohnishi Y, Ooshima A.

    J Cataract Refract Surg. 2001 Jul;27(7):1076-8.PMID: 11489579 [PubMed - indexed for MEDLINE]Related articles

    45.

    Decreased type III and V collagen expression in chorionic villi of hydatidiform mole.

    Iwahashi M, Muragaki Y, Ooshima A, Nakano R.

    J Clin Endocrinol Metab. 2001 Jul;86(7):3346-50.PMID: 11443210 [PubMed - indexed for MEDLINE]Related articlesFree article

    46.

    Accumulation of latent transforming growth factor-beta binding protein-1 and TGF beta 1 in extracellular matrix of filtering bleb and of cultured human subconjunctival fibroblasts.

    Saika S, Yamanaka O, Baba Y, Kawashima Y, Shirai K, Miyamoto T, Okada Y, Ohnishi Y, Ooshima A.

    Graefes Arch Clin Exp Ophthalmol. 2001 Mar;239(3):234-41.PMID: 11405075 [PubMed - indexed for MEDLINE]Related articles

    47.

    Overexpression of type IV collagen in chorionic villi in hydatidiform mole.

    Iwahashi M, Muragaki Y, Ooshima A, Nakano R.

    J Clin Endocrinol Metab. 2001 Jun;86(6):2649-52.PMID: 11397867 [PubMed - indexed for MEDLINE]Related articlesFree article

    48.

    Smad translocation and growth suppression in lens epithelial cells by endogenous TGFbeta2 during wound repair.

    Saika S, Okada Y, Miyamoto T, Ohnishi Y, Ooshima A, McAvoy JW.

    Exp Eye Res. 2001 Jun;72(6):679-86.PMID: 11384156 [PubMed - indexed for MEDLINE]Related articles

    49.

    A nonsense mutation in TRPS1 in a Japanese family with tricho-rhino-phalangeal syndrome type I.

    Hatamura I, Kanauchi Y, Takahara M, Fujiwara M, Muragaki Y, Ooshima A, Ogino T.

    Clin Genet. 2001 May;59(5):366-7. No abstract available. PMID: 11359471 [PubMed - indexed for MEDLINE]Related articles

    50.

    Expression of involucrin by ocular surface epithelia of patients with benign and malignant disorders.

    Saika S, Minamide A, Tanaka T, Miyamoto T, Okada Y, Kawashima Y, Ohnishi Y, Ooshima A, Kao WW.

    Curr Eye Res. 2000 Nov;21(5):877-85.PMID: 11262609 [PubMed - indexed for MEDLINE]Related articles

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