PubMed

Effect of xanthone from Kielmeyera coriacea stems on serotonergic neurons of the median raphe nucleus.

Sela VR, Hattanda I, Albrecht CM, De Almeida CB, Obici S, Cortez DA, Audi EA.

Phytomedicine. 2009 Aug 10. [Epub ahead of print]PMID: 19674881 [PubMed - as supplied by publisher]Related articles

Targeting the CNS to treat type 2 diabetes.

Sandoval DA, Obici S, Seeley RJ.

Nat Rev Drug Discov. 2009 May;8(5):386-98. Review.PMID: 19404312 [PubMed - indexed for MEDLINE]Related articles

Minireview: Molecular targets for obesity therapy in the brain.

Obici S.

Endocrinology. 2009 Jun;150(6):2512-7. Epub 2009 Apr 16. Review.PMID: 19372196 [PubMed - indexed for MEDLINE]Related articles

Food intake-independent effects of CB1 antagonism on glucose and lipid metabolism.

Cota D, Sandoval DA, Olivieri M, Prodi E, D'Alessio DA, Woods SC, Seeley RJ, Obici S.

Obesity (Silver Spring). 2009 Aug;17(8):1641-5. Epub 2009 Mar 26.PMID: 19325539 [PubMed - indexed for MEDLINE]Related articles

Oral glutamine dipeptide prevents against prolonged hypoglycemia induced by Detemir insulin in rats.

Felisberto-Junior AM, Manso FC, Gazola VA, Obici S, Geisler SA, Bazotte RB.

Biol Pharm Bull. 2009 Feb;32(2):232-6.PMID: 19182381 [PubMed - indexed for MEDLINE]Related articlesFree article

Liver glycogen metabolism during short-term insulin-induced hypoglycemia in fed rats.

Obici S, Lopes-Bertolini G, Curi R, Bazotte RB.

Cell Biochem Funct. 2008 Oct;26(7):755-9.PMID: 18800354 [PubMed - indexed for MEDLINE]Related articles

Contribution of hepatic glycogenolysis and gluconeogenesis in the defense against short-term insulin induced hypoglycemia in rats.

Nascimento KF, Garcia RF, Gazola VA, de Souza HM, Obici S, Bazotte RB.

Life Sci. 2008 May 7;82(19-20):1018-22. Epub 2008 Mar 8.PMID: 18433794 [PubMed - indexed for MEDLINE]Related articles

Preliminary toxicity study of dichloromethane extract of Kielmeyera coriacea stems in mice and rats.

Obici S, Otobone FJ, da Silva Sela VR, Ishida K, da Silva JC, Nakamura CV, Garcia Cortez DA, Audi EA.

J Ethnopharmacol. 2008 Jan 4;115(1):131-9. Epub 2007 Sep 25.PMID: 17997061 [PubMed - indexed for MEDLINE]Related articles

Transgenic MSH overexpression attenuates the metabolic effects of a high-fat diet.

Lee M, Kim A, Chua SC Jr, Obici S, Wardlaw SL.

Am J Physiol Endocrinol Metab. 2007 Jul;293(1):E121-31. Epub 2007 Mar 20.PMID: 17374695 [PubMed - indexed for MEDLINE]Related articlesFree article

Central nervous system and control of endogenous glucose production.

Demuro G, Obici S.

Curr Diab Rep. 2006 Jun;6(3):188-93. Review.PMID: 16898570 [PubMed - indexed for MEDLINE]Related articles

Minireview: the brain as a molecular target for diabetic therapy.

Prodi E, Obici S.

Endocrinology. 2006 Jun;147(6):2664-9. Epub 2006 Mar 23. Review.PMID: 16556761 [PubMed - indexed for MEDLINE]Related articlesFree article

Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats.

Pocai A, Lam TK, Obici S, Gutierrez-Juarez R, Muse ED, Arduini A, Rossetti L.

J Clin Invest. 2006 Apr;116(4):1081-91. Epub 2006 Mar 9.PMID: 16528412 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation.

Du X, Edelstein D, Obici S, Higham N, Zou MH, Brownlee M.

J Clin Invest. 2006 Apr;116(4):1071-80. Epub 2006 Mar 9.PMID: 16528409 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular disruption of hypothalamic nutrient sensing induces obesity.

He W, Lam TK, Obici S, Rossetti L.

Nat Neurosci. 2006 Feb;9(2):227-33. Epub 2006 Jan 15.PMID: 16415870 [PubMed - indexed for MEDLINE]Related articles

Central leptin acutely reverses diet-induced hepatic insulin resistance.

Pocai A, Morgan K, Buettner C, Gutierrez-Juarez R, Obici S, Rossetti L.

Diabetes. 2005 Nov;54(11):3182-9.PMID: 16249443 [PubMed - indexed for MEDLINE]Related articlesFree article

A brain-liver circuit regulates glucose homeostasis.

Pocai A, Obici S, Schwartz GJ, Rossetti L.

Cell Metab. 2005 Jan;1(1):53-61.PMID: 16054044 [PubMed - indexed for MEDLINE]Related articles

Restoration of liver insulin signaling in Insr knockout mice fails to normalize hepatic insulin action.

Okamoto H, Obici S, Accili D, Rossetti L.

J Clin Invest. 2005 May;115(5):1314-22.PMID: 15864351 [PubMed - indexed for MEDLINE]Related articlesFree article

Severe impairment in liver insulin signaling fails to alter hepatic insulin action in conscious mice.

Buettner C, Patel R, Muse ED, Bhanot S, Monia BP, McKay R, Obici S, Rossetti L.

J Clin Invest. 2005 May;115(5):1306-13.PMID: 15864350 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypothalamic K(ATP) channels control hepatic glucose production.

Pocai A, Lam TK, Gutierrez-Juarez R, Obici S, Schwartz GJ, Bryan J, Aguilar-Bryan L, Rossetti L.

Nature. 2005 Apr 21;434(7036):1026-31.PMID: 15846348 [PubMed - indexed for MEDLINE]Related articles

Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis.

Lam TK, Pocai A, Gutierrez-Juarez R, Obici S, Bryan J, Aguilar-Bryan L, Schwartz GJ, Rossetti L.

Nat Med. 2005 Mar;11(3):320-7. Epub 2005 Feb 27.PMID: 15735652 [PubMed - indexed for MEDLINE]Related articles

Melanocortin-independent effects of leptin on hepatic glucose fluxes.

Gutiérrez-Juárez R, Obici S, Rossetti L.

J Biol Chem. 2004 Nov 26;279(48):49704-15. Epub 2004 Sep 10.PMID: 15364916 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of resistin in diet-induced hepatic insulin resistance.

Muse ED, Obici S, Bhanot S, Monia BP, McKay RA, Rajala MW, Scherer PE, Rossetti L.

J Clin Invest. 2004 Jul;114(2):232-9.PMID: 15254590 [PubMed - indexed for MEDLINE]Related articlesFree article

Abnormal glucose homeostasis due to chronic hyperresistinemia.

Rangwala SM, Rich AS, Rhoades B, Shapiro JS, Obici S, Rossetti L, Lazar MA.

Diabetes. 2004 Aug;53(8):1937-41. Epub 2004 Jun 9.PMID: 15189975 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypothalamic responses to long-chain fatty acids are nutritionally regulated.

Morgan K, Obici S, Rossetti L.

J Biol Chem. 2004 Jul 23;279(30):31139-48. Epub 2004 May 19.PMID: 15155754 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of fasted blood glucose by resistin.

Banerjee RR, Rangwala SM, Shapiro JS, Rich AS, Rhoades B, Qi Y, Wang J, Rajala MW, Pocai A, Scherer PE, Steppan CM, Ahima RS, Obici S, Rossetti L, Lazar MA.

Science. 2004 Feb 20;303(5661):1195-8.PMID: 14976316 [PubMed - indexed for MEDLINE]Related articlesFree article

A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity.

Combs TP, Pajvani UB, Berg AH, Lin Y, Jelicks LA, Laplante M, Nawrocki AR, Rajala MW, Parlow AF, Cheeseboro L, Ding YY, Russell RG, Lindemann D, Hartley A, Baker GR, Obici S, Deshaies Y, Ludgate M, Rossetti L, Scherer PE.

Endocrinology. 2004 Jan;145(1):367-83. Epub 2003 Oct 23.PMID: 14576179 [PubMed - indexed for MEDLINE]Related articlesFree article

Minireview: nutrient sensing and the regulation of insulin action and energy balance.

Obici S, Rossetti L.

Endocrinology. 2003 Dec;144(12):5172-8. Epub 2003 Sep 11. Review.PMID: 12970158 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production.

Obici S, Feng Z, Arduini A, Conti R, Rossetti L.

Nat Med. 2003 Jun;9(6):756-61. Epub 2003 May 18.PMID: 12754501 [PubMed - indexed for MEDLINE]Related articles

Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice.

Gelling RW, Du XQ, Dichmann DS, Romer J, Huang H, Cui L, Obici S, Tang B, Holst JJ, Fledelius C, Johansen PB, Rossetti L, Jelicks LA, Serup P, Nishimura E, Charron MJ.

Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1438-43. Epub 2003 Jan 24.PMID: 12552113 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipose-derived resistin and gut-derived resistin-like molecule-beta selectively impair insulin action on glucose production.

Rajala MW, Obici S, Scherer PE, Rossetti L.

J Clin Invest. 2003 Jan;111(2):225-30.PMID: 12531878 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypothalamic insulin signaling is required for inhibition of glucose production.

Obici S, Zhang BB, Karkanias G, Rossetti L.

Nat Med. 2002 Dec;8(12):1376-82. Epub 2002 Nov 11.PMID: 12426561 [PubMed - indexed for MEDLINE]Related articles

Identification of a biochemical link between energy intake and energy expenditure.

Obici S, Wang J, Chowdury R, Feng Z, Siddhanta U, Morgan K, Rossetti L.

J Clin Invest. 2002 Jun;109(12):1599-605.PMID: 12070307 [PubMed - indexed for MEDLINE]Related articlesFree article

Decreasing hypothalamic insulin receptors causes hyperphagia and insulin resistance in rats.

Obici S, Feng Z, Karkanias G, Baskin DG, Rossetti L.

Nat Neurosci. 2002 Jun;5(6):566-72.PMID: 12021765 [PubMed - indexed for MEDLINE]Related articles

Central administration of oleic acid inhibits glucose production and food intake.

Obici S, Feng Z, Morgan K, Stein D, Karkanias G, Rossetti L.

Diabetes. 2002 Feb;51(2):271-5.PMID: 11812732 [PubMed - indexed for MEDLINE]Related articlesFree article

Endogenous glucose production is inhibited by the adipose-derived protein Acrp30.

Combs TP, Berg AH, Obici S, Scherer PE, Rossetti L.

J Clin Invest. 2001 Dec;108(12):1875-81.PMID: 11748271 [PubMed - indexed for MEDLINE]Related articlesFree article

Overfeeding rapidly induces leptin and insulin resistance.

Wang J, Obici S, Morgan K, Barzilai N, Feng Z, Rossetti L.

Diabetes. 2001 Dec;50(12):2786-91.PMID: 11723062 [PubMed - indexed for MEDLINE]Related articlesFree article

Central melanocortin receptors regulate insulin action.

Obici S, Feng Z, Tan J, Liu L, Karkanias G, Rossetti L.

J Clin Invest. 2001 Oct;108(7):1079-85.PMID: 11581309 [PubMed - indexed for MEDLINE]Related articlesFree article

A multicopy transcription-repair gene, BTF2p44, maps to the SMA region and demonstrates SMA associated deletions.

Carter TA, Bönnemann CG, Wang CH, Obici S, Parano E, De Fatima Bonaldo M, Ross BM, Penchaszadeh GK, Mackenzie A, Soares MB, Kunkel LM, Gilliam TC.

Hum Mol Genet. 1997 Feb;6(2):229-36.PMID: 9063743 [PubMed - indexed for MEDLINE]Related articlesFree article

The v-Ki-Ras oncogene alters cAMP nuclear signaling by regulating the location and the expression of cAMP-dependent protein kinase IIbeta.

Feliciello A, Giuliano P, Porcellini A, Garbi C, Obici S, Mele E, Angotti E, Grieco D, Amabile G, Cassano S, Li Y, Musti AM, Rubin CS, Gottesman ME, Avvedimento EV.

J Biol Chem. 1996 Oct 11;271(41):25350-9.PMID: 8810300 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of the 5' flanking region and gene encoding the mouse interferon-gamma receptor.

Raval P, Obici S, Russell SW, Murphy WJ.

Gene. 1995 Mar 10;154(2):219-23.PMID: 7890167 [PubMed - indexed for MEDLINE]Related articles

Refinement of the spinal muscular atrophy locus by genetic and physical mapping.

Wang CH, Kleyn PW, Vitale E, Ross BM, Lien L, Xu J, Carter TA, Brzustowicz LM, Obici S, Selig S, et al.

Am J Hum Genet. 1995 Jan;56(1):202-9.PMID: 7825579 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of thyrotropin receptor gene expression in rat FRTL-5 thyroid cells.

Saji M, Akamizu T, Sanchez M, Obici S, Avvedimento E, Gottesman ME, Kohn LD.

Endocrinology. 1992 Jan;130(1):520-33.PMID: 1309347 [PubMed - indexed for MEDLINE]Related articles

A replica filter assay for expression of ion transport proteins.

Obici S, al-Awqati Q, Avvedimento EV, Gottesman ME.

Am J Physiol. 1991 Oct;261(4 Pt 1):C708-12.PMID: 1928330 [PubMed - indexed for MEDLINE]Related articles

Stable expression of a secreted form of the mouse IFN-gamma receptor by rat cells.

Fernando LP, LeClaire RD, Obici S, Zavodny PJ, Russell SW, Pace JL.

J Immunol. 1991 Jul 15;147(2):541-7.PMID: 1830066 [PubMed - indexed for MEDLINE]Related articles

[Prevention in the pregnancy-puerperium cycle: a model of interdisciplinary action at the Hospital Universitário Regional do Norte do Paraná]

Narciso AM, Moraes CG, Imperatriz DM, Do Carmo LH, Assad MA, Obici SM, Taques VL.

Semina. 1991 Jun;12(2):97-101. Portuguese. PMID: 1845314 [PubMed - indexed for MEDLINE]Related articles

Reversible inhibition of a thyroid-specific trans-acting factor by Ras.

Avvedimento VE, Musti AM, Ueffing M, Obici S, Gallo A, Sanchez M, DeBrasi D, Gottesman ME.

Genes Dev. 1991 Jan;5(1):22-8.PMID: 1989905 [PubMed - indexed for MEDLINE]Related articlesFree article

Human CD8 alpha glycoprotein is expressed at the apical plasma membrane domain in permanently transformed MDCK II clones.

Migliaccio G, Zurzolo C, Nitsch L, Obici S, Lotti LV, Torrisi MR, Pascale MC, Leone A, Bonatti S.

Eur J Cell Biol. 1990 Aug;52(2):291-6.PMID: 2127916 [PubMed - indexed for MEDLINE]Related articles

Extinction and activation of the thyroglobulin promoter in hybrids of differentiated and transformed thyroid cells.

Bonapace IM, Sanchez M, Obici S, Gallo A, Garofalo S, Gentile R, Cocozza S, Avvedimento EV.

Mol Cell Biol. 1990 Mar;10(3):1033-40.PMID: 2406559 [PubMed - indexed for MEDLINE]Related articlesFree article

Reactivation of thyroglobulin gene expression in transformed thyroid cells by 5-azacytidine.

Avvedimento EV, Obici S, Sanchez M, Gallo A, Musti A, Gottesman ME.

Cell. 1989 Sep 22;58(6):1135-42.PMID: 2476239 [PubMed - indexed for MEDLINE]Related articles

Molecular characterization of a gene of the 'EGF family' expressed in undifferentiated human NTERA2 teratocarcinoma cells.

Ciccodicola A, Dono R, Obici S, Simeone A, Zollo M, Persico MG.

EMBO J. 1989 Jul;8(7):1987-91.PMID: 2792079 [PubMed - indexed for MEDLINE]Related articlesFree article