PubMed

HDAC7 and FoxA1 in estrogen-mediated repression of RPRM.

Malik S, Jiang S, Garee JP, Verdin E, Lee AV, O'Malley BW, Zhang M, Belaguli NS, Oesterreich S.

Mol Cell Biol. 2009 Nov 16. [Epub ahead of print]PMID: 19917725 [PubMed - as supplied by publisher]Related articles

An estrogen receptor alpha activity indicator model in mice.

Han SJ, O'Malley BW, Demayo FJ.

Genesis. 2009 Oct 30. [Epub ahead of print]PMID: 19882671 [PubMed - as supplied by publisher]Related articles

Maturation of microRNA is hormonally regulated by a nuclear receptor.

Yamagata K, Fujiyama S, Ito S, Ueda T, Murata T, Naitou M, Takeyama K, Minami Y, O'Malley BW, Kato S.

Mol Cell. 2009 Oct 23;36(2):340-7.PMID: 19854141 [PubMed - in process]Related articles

Minireview: The SRC Family of Coactivators: An Entree to Understanding a Subset of Polygenic Diseases?

Lonard DM, Kumar R, O'Malley BW.

Mol Endocrinol. 2009 Oct 21. [Epub ahead of print]PMID: 19846539 [PubMed - as supplied by publisher]Related articles

Nuclear receptor coregulators in cancer biology.

O'Malley BW, Kumar R.

Cancer Res. 2009 Nov 1;69(21):8217-22. Epub 2009 Oct 20.PMID: 19843848 [PubMed - in process]Related articles

Biochemical control of CARM1 enzymatic activity by phosphorylation.

Feng Q, He B, Jung SY, Song Y, Qin J, Tsai SY, Tsai MJ, O'Malley BW.

J Biol Chem. 2009 Oct 20. [Epub ahead of print]PMID: 19843527 [PubMed - as supplied by publisher]Related articlesFree article

Inflammatory pseudotumor of the trigeminal nerve: a neoplastic mimic you do not want to miss.

Seol JG, Loevner LA, O'Malley BW Jr, Grady MS.

AJNR Am J Neuroradiol. 2009 Nov;30(10):1941-3. Epub 2009 Sep 12.PMID: 19749214 [PubMed - in process]Related articles

Silk-elastinlike protein polymer hydrogels for localized adenoviral gene therapy of head and neck tumors.

Greish K, Araki K, Li D, O'Malley BW Jr, Dandu R, Frandsen J, Cappello J, Ghandehari H.

Biomacromolecules. 2009 Aug 10;10(8):2183-8.PMID: 19722557 [PubMed - indexed for MEDLINE]Related articles

Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family.

Xu J, Wu RC, O'Malley BW.

Nat Rev Cancer. 2009 Sep;9(9):615-30. Review.PMID: 19701241 [PubMed - indexed for MEDLINE]Related articles

Head and neck squamous cell carcinoma targeted chemosensitization.

Figures MR, Wobb J, Araki K, Liu T, Xu L, Zhu H, O'Malley BW Jr, Li D.

Otolaryngol Head Neck Surg. 2009 Aug;141(2):177-83.PMID: 19643248 [PubMed - indexed for MEDLINE]Related articles

Current management of juvenile nasopharyngeal angiofibroma: a tertiary center experience 1999-2007.

Bleier BS, Kennedy DW, Palmer JN, Chiu AG, Bloom JD, O'Malley BW Jr.

Am J Rhinol Allergy. 2009 May-Jun;23(3):328-30.PMID: 19490810 [PubMed - indexed for MEDLINE]Related articles

Molecular disruption of RAD50 sensitizes human tumor cells to cisplatin-based chemotherapy.

Abuzeid WM, Jiang X, Shi G, Wang H, Paulson D, Araki K, Jungreis D, Carney J, O'Malley BW Jr, Li D.

J Clin Invest. 2009 Jul;119(7):1974-85.PMID: 19487811 [PubMed - indexed for MEDLINE]Related articlesFree article

Endoscopic closure of CSF rhinorrhea: 193 cases over 21 years.

Banks CA, Palmer JN, Chiu AG, O'Malley BW Jr, Woodworth BA, Kennedy DW.

Otolaryngol Head Neck Surg. 2009 Jun;140(6):826-33. Epub 2009 Feb 28.PMID: 19467398 [PubMed - indexed for MEDLINE]Related articles

Skeletal consequences of deletion of steroid receptor coactivator-2/transcription intermediary factor-2.

Mödder UI, Monroe DG, Fraser DG, Spelsberg TC, Rosen CJ, Géhin M, Chambon P, O'Malley BW, Khosla S.

J Biol Chem. 2009 Jul 10;284(28):18767-77. Epub 2009 May 7.PMID: 19423703 [PubMed - indexed for MEDLINE]Related articles

Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas.

McKenna NJ, Cooney AJ, DeMayo FJ, Downes M, Glass CK, Lanz RB, Lazar MA, Mangelsdorf DJ, Moore DD, Qin J, Steffen DL, Tsai MJ, Tsai SY, Yu R, Margolis RN, Evans RM, O'Malley BW.

Mol Endocrinol. 2009 Jun;23(6):740-6. Epub 2009 May 7. Review. Erratum in: Mol Endocrinol. 2009 Sep;23(9):1522. PMID: 19423650 [PubMed - indexed for MEDLINE]Related articles

Foxa2-dependent hepatic gene regulatory networks depend on physiological state.

Bochkis IM, Schug J, Rubins NE, Chopra AR, O'Malley BW, Kaestner KH.

Physiol Genomics. 2009 Jul 9;38(2):186-95. Epub 2009 May 5.PMID: 19417011 [PubMed - indexed for MEDLINE]Related articles

OTU Domain-containing ubiquitin aldehyde-binding protein 1 (OTUB1) deubiquitinates estrogen receptor (ER) alpha and affects ERalpha transcriptional activity.

Stanisić V, Malovannaya A, Qin J, Lonard DM, O'Malley BW.

J Biol Chem. 2009 Jun 12;284(24):16135-45. Epub 2009 Apr 21.PMID: 19383985 [PubMed - indexed for MEDLINE]Related articles

Chitosan glycerophosphate-based semirigid dexamethasone eluting biodegradable stent.

Bleier BS, Paulson DP, O'Malley BW, Li D, Palmer JN, Chiu AG, Cohen NA.

Am J Rhinol Allergy. 2009 Jan-Feb;23(1):76-9.PMID: 19379617 [PubMed - indexed for MEDLINE]Related articles

Transoral robotic surgery: does the ends justify the means?

Weinstein GS, O'Malley BW Jr, Desai SC, Quon H.

Curr Opin Otolaryngol Head Neck Surg. 2009 Apr;17(2):126-31. Review.PMID: 19342953 [PubMed - indexed for MEDLINE]Related articles

Endoscopic resection of advanced anterior skull base lesions: oncologically safe?

Cohen MA, Liang J, Cohen IJ, Grady MS, O'Malley BW Jr, Newman JG.

ORL J Otorhinolaryngol Relat Spec. 2009;71(3):123-8. Epub 2009 Mar 24.PMID: 19321974 [PubMed - indexed for MEDLINE]Related articles

The "fourth dimension" of gene transcription.

O'Malley BW.

Mol Endocrinol. 2009 May;23(5):587-9. Epub 2009 Feb 12.PMID: 19221049 [PubMed - indexed for MEDLINE]Related articles

Cytotoxicity and antiangiogenesis by fibroblast growth factor 2-targeted Ad-TK cancer gene therapy.

Saito K, Khan K, Sosnowski B, Li D, O'Malley BW Jr.

Laryngoscope. 2009 Apr;119(4):665-74.PMID: 19213040 [PubMed - indexed for MEDLINE]Related articles

The predictive and therapeutic value of thymidine phosphorylase and dihydropyrimidine dehydrogenase in capecitabine (Xeloda)-based chemotherapy for head and neck cancer.

Saito K, Khan K, Yu SZ, Ronson S, Rhee J, Li G, Van Echo D, Suntharalingam M, O'Malley BW Jr, Li D.

Laryngoscope. 2009 Jan;119(1):82-8.PMID: 19117293 [PubMed - indexed for MEDLINE]Related articles

Disruption of the SRC-1 gene in mice suppresses breast cancer metastasis without affecting primary tumor formation.

Wang S, Yuan Y, Liao L, Kuang SQ, Tien JC, O'Malley BW, Xu J.

Proc Natl Acad Sci U S A. 2009 Jan 6;106(1):151-6. Epub 2008 Dec 24.PMID: 19109434 [PubMed - indexed for MEDLINE]Related articlesFree article

Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease.

Chopra AR, Louet JF, Saha P, An J, Demayo F, Xu J, York B, Karpen S, Finegold M, Moore D, Chan L, Newgard CB, O'Malley BW.

Science. 2008 Nov 28;322(5906):1395-9.PMID: 19039140 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of endoscopic and microscopic removal of pituitary adenomas: single-surgeon experience and the learning curve.

O'Malley BW Jr, Grady MS, Gabel BC, Cohen MA, Heuer GG, Pisapia J, Bohman LE, Leibowitz JM.

Neurosurg Focus. 2008;25(6):E10.PMID: 19035697 [PubMed - indexed for MEDLINE]Related articles

Multi-modulation of nuclear receptor coactivators through posttranslational modifications.

Han SJ, Lonard DM, O'Malley BW.

Trends Endocrinol Metab. 2009 Jan;20(1):8-15. Epub 2008 Nov 18. Review.PMID: 19019695 [PubMed - indexed for MEDLINE]Related articles

The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1{alpha}.

Coste A, Louet JF, Lagouge M, Lerin C, Antal MC, Meziane H, Schoonjans K, Puigserver P, O'Malley BW, Auwerx J.

Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):17187-92. Epub 2008 Oct 28.PMID: 18957541 [PubMed - indexed for MEDLINE]Related articlesFree article

Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover.

Li C, Liang YY, Feng XH, Tsai SY, Tsai MJ, O'Malley BW.

Mol Cell. 2008 Sep 26;31(6):835-49.PMID: 18922467 [PubMed - indexed for MEDLINE]Related articlesFree article

Dual roles for coactivator activator and its counterbalancing isoform coactivator modulator in human kidney cell tumorigenesis.

Kang YK, Schiff R, Ko L, Wang T, Tsai SY, Tsai MJ, O'Malley BW.

Cancer Res. 2008 Oct 1;68(19):7887-96.PMID: 18829545 [PubMed - indexed for MEDLINE]Related articlesFree article

Coactivators and corepressors: what's in a name?

O'Malley BW, McKenna NJ.

Mol Endocrinol. 2008 Oct;22(10):2213-4. Epub 2008 Aug 13.PMID: 18701638 [PubMed - indexed for MEDLINE]Related articlesFree article

The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression.

Qin L, Liao L, Redmond A, Young L, Yuan Y, Chen H, O'Malley BW, Xu J.

Mol Cell Biol. 2008 Oct;28(19):5937-50. Epub 2008 Jul 21.PMID: 18644862 [PubMed - indexed for MEDLINE]Related articlesFree article

Dynamic regulation of progesterone receptor activity in female reproductive tissues.

Han SJ, DeMayo FJ, O'Malley BW.

Ernst Schering Found Symp Proc. 2007;(1):25-43. Review.PMID: 18543433 [PubMed - indexed for MEDLINE]Related articles

Steroid receptor coactivator 2: an essential coregulator of progestin-induced uterine and mammary morphogenesis.

Mukherjee A, Amato P, Craig-Allred D, DeMayo FJ, O'Malley BW, Lydon JP.

Ernst Schering Found Symp Proc. 2007;(1):55-76. Review.PMID: 18540568 [PubMed - indexed for MEDLINE]Related articles

Retinoblastoma RB94 enhances radiation treatment of head and neck squamous cell carcinoma.

Araki K, Ahmad SM, Li G, Bray DA Jr, Saito K, Wang D, Wirtz U, Sreedharan S, O'Malley BW Jr, Li D.

Clin Cancer Res. 2008 Jun 1;14(11):3514-9.PMID: 18519784 [PubMed - indexed for MEDLINE]Related articlesFree article

Cracking the coregulator codes.

O'Malley BW, Qin J, Lanz RB.

Curr Opin Cell Biol. 2008 Jun;20(3):310-5. Epub 2008 May 20. Review.PMID: 18499426 [PubMed - indexed for MEDLINE]Related articles

The nuclear receptor coactivator amplified in breast cancer-1 is required for Neu (ErbB2/HER2) activation, signaling, and mammary tumorigenesis in mice.

Fereshteh MP, Tilli MT, Kim SE, Xu J, O'Malley BW, Wellstein A, Furth PA, Riegel AT.

Cancer Res. 2008 May 15;68(10):3697-706.PMID: 18483252 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene transcription: two worlds merged.

Lonard DM, O'Malley BW.

Nature. 2008 Apr 24;452(7190):946-7. No abstract available. PMID: 18432236 [PubMed - indexed for MEDLINE]Related articles

SRC-3 transcription-coupled activation, degradation, and the ubiquitin clock: is there enough coactivator to go around in cells?

Lonard DM, O'Malley BW.

Sci Signal. 2008 Apr 1;1(13):pe16.PMID: 18385039 [PubMed - indexed for MEDLINE]Related articles

Atypical protein kinase C regulates dual pathways for degradation of the oncogenic coactivator SRC-3/AIB1.

Yi P, Feng Q, Amazit L, Lonard DM, Tsai SY, Tsai MJ, O'Malley BW.

Mol Cell. 2008 Feb 29;29(4):465-76.PMID: 18313384 [PubMed - indexed for MEDLINE]Related articlesFree article

Bone growth and turnover in progesterone receptor knockout mice.

Rickard DJ, Iwaniec UT, Evans G, Hefferan TE, Hunter JC, Waters KM, Lydon JP, O'Malley BW, Khosla S, Spelsberg TC, Turner RT.

Endocrinology. 2008 May;149(5):2383-90. Epub 2008 Feb 14.PMID: 18276762 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel controlled local drug delivery system for inner ear disease.

Paulson DP, Abuzeid W, Jiang H, Oe T, O'Malley BW, Li D.

Laryngoscope. 2008 Apr;118(4):706-11.PMID: 18182968 [PubMed - indexed for MEDLINE]Related articles

Novel adenoviral gene delivery system targeted against head and neck cancer.

Li D, Guang W, Abuzeid WM, Roy S, Gao GP, Sauk JJ, O'Malley BW Jr.

Laryngoscope. 2008 Apr;118(4):650-8.PMID: 18176343 [PubMed - indexed for MEDLINE]Related articles

Ataxia telangiectasia-mutated and p53 are potential mediators of chloroquine-induced resistance to mammary carcinogenesis.

Loehberg CR, Thompson T, Kastan MB, Maclean KH, Edwards DG, Kittrell FS, Medina D, Conneely OM, O'Malley BW.

Cancer Res. 2007 Dec 15;67(24):12026-33.PMID: 18089834 [PubMed - indexed for MEDLINE]Related articlesFree article

Transoral robotic surgery: radical tonsillectomy.

Weinstein GS, O'Malley BW Jr, Snyder W, Sherman E, Quon H.

Arch Otolaryngol Head Neck Surg. 2007 Dec;133(12):1220-6.PMID: 18086963 [PubMed - indexed for MEDLINE]Related articlesFree article

Robotic skull base surgery: preclinical investigations to human clinical application.

O'Malley BW Jr, Weinstein GS.

Arch Otolaryngol Head Neck Surg. 2007 Dec;133(12):1215-9.PMID: 18086962 [PubMed - indexed for MEDLINE]Related articlesFree article

The skeletal response to estrogen is impaired in female but not in male steroid receptor coactivator (SRC)-1 knock out mice.

Mödder UI, Sanyal A, Xu J, O'Malley BW, Spelsberg TC, Khosla S.

Bone. 2008 Feb;42(2):414-21. Epub 2007 Nov 4.PMID: 18055287 [PubMed - indexed for MEDLINE]Related articlesFree article

Report of a case of sinonasal undifferentiated carcinoma arising in a background of extensive nasal gliomatosis.

Tetzlaff MT, Liu P, O'Malley BW Jr, LiVolsi VA, Elder D.

Head Neck. 2008 Apr;30(4):549-55.PMID: 17972313 [PubMed - indexed for MEDLINE]Related articles

Robotic anterior and midline skull base surgery: preclinical investigations.

O'Malley BW Jr, Weinstein GS.

Int J Radiat Oncol Biol Phys. 2007;69(2 Suppl):S125-8.PMID: 17848280 [PubMed - indexed for MEDLINE]Related articles

A repressive role for prohibitin in estrogen signaling.

He B, Feng Q, Mukherjee A, Lonard DM, DeMayo FJ, Katzenellenbogen BS, Lydon JP, O'Malley BW.

Mol Endocrinol. 2008 Feb;22(2):344-60. Epub 2007 Oct 11.PMID: 17932104 [PubMed - indexed for MEDLINE]Related articlesFree article