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Exertional dyspnea in chronic obstructive pulmonary disease: mechanisms and treatment approaches.

Ora J, Jensen D, Oʼdonnell DE.

Curr Opin Pulm Med. 2009 Nov 18. [Epub ahead of print]PMID: 19926997 [PubMed - as supplied by publisher]Related articles

Effects of Obesity on Perceptual and Mechanical Responses to Bronchoconstriction in Asthma.

Deesomchok A, Fisher T, Webb KA, Ora J, Lam YM, Lougheed MD, O'Donnell DE.

Am J Respir Crit Care Med. 2009 Nov 12. [Epub ahead of print]PMID: 19910609 [PubMed - as supplied by publisher]Related articles

Combined effects of obesity and chronic obstructive pulmonary disease on dyspnea and exercise tolerance.

Ora J, Laveneziana P, Ofir D, Deesomchok A, Webb KA, O'Donnell DE.

Am J Respir Crit Care Med. 2009 Nov 15;180(10):964-71.PMID: 19897773 [PubMed - in process]Related articles

Performance during constant workrate cycling exercise in women with COPD and hyperinflation.

Laviolette L, O'Donnell DE, Webb KA, Hamilton AL, Kesten S, Maltais F.

COPD. 2009 Oct;6(5):340-51.PMID: 19863363 [PubMed - in process]Related articles

Chronic obstructive pulmonary disease in men and women: myths and reality.

Camp PG, O'Donnell DE, Postma DS.

Proc Am Thorac Soc. 2009 Sep 15;6(6):535-8.PMID: 19741264 [PubMed - in process]Related articlesFree article

Bronchodilator effect on ventilatory, pulmonary gas exchange, and heart rate kinetics during high-intensity exercise in COPD.

Laveneziana P, Palange P, Ora J, Martolini D, O'Donnell DE.

Eur J Appl Physiol. 2009 Aug 27. [Epub ahead of print]PMID: 19711095 [PubMed - as supplied by publisher]Related articles

Combined Effects of Obesity and COPD on Dyspnea and Exercise Tolerance.

Ora J, Laveneziana P, Ofir D, Deesomchok A, Webb KA, O'Donnell DE.

Am J Respir Crit Care Med. 2009 Jul 30. [Epub ahead of print]PMID: 19644044 [PubMed - as supplied by publisher]Related articles

Vastus lateralis Na(+)-K(+)-ATPase activity, protein, and isoform distribution in chronic obstructive pulmonary disease.

Green HJ, Burnett ME, D'Arsigny CL, Webb KA, McBride I, Ouyang J, O'Donnell DE.

Muscle Nerve. 2009 Jul;40(1):62-8.PMID: 19472354 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of activity-related dyspnea in pulmonary diseases.

O'Donnell DE, Ora J, Webb KA, Laveneziana P, Jensen D.

Respir Physiol Neurobiol. 2009 May 30;167(1):116-32. Epub 2009 Feb 7. Review.PMID: 19450767 [PubMed - indexed for MEDLINE]Related articles

Effects of pregnancy, obesity and aging on the intensity of perceived breathlessness during exercise in healthy humans.

Jensen D, Ofir D, O'Donnell DE.

Respir Physiol Neurobiol. 2009 May 30;167(1):87-100. Epub 2009 Feb 7. Review.PMID: 19450766 [PubMed - indexed for MEDLINE]Related articles

The clinical physiology and integrative neurobiology of dyspnea: introduction to the Special Issue of Respir. Physiol. Neurobiol.

Fisher JT, O'Donnell DE.

Respir Physiol Neurobiol. 2009 May 30;167(1):1. Epub 2009 Feb 24. No abstract available. PMID: 19450764 [PubMed - indexed for MEDLINE]Related articles

Reliability of ventilatory parameters during cycle ergometry in multicentre trials in COPD.

O'Donnell DE, Travers J, Webb KA, He Z, Lam YM, Hamilton A, Kesten S, Maltais F, Magnussen H.

Eur Respir J. 2009 Oct;34(4):866-74. Epub 2009 Mar 12.PMID: 19282342 [PubMed - in process]Related articles

Mechanisms of activity-related breathlessness in healthy human pregnancy.

Jensen D, Webb KA, Davies GA, O'Donnell DE.

Eur J Appl Physiol. 2009 May;106(2):253-65. Epub 2009 Mar 3.PMID: 19255773 [PubMed - indexed for MEDLINE]Related articles

Effect of biventricular pacing on ventilatory and perceptual responses to exercise in patients with stable chronic heart failure.

Laveneziana P, O'Donnell DE, Ofir D, Agostoni P, Padeletti L, Ricciardi G, Palange P, Duranti R, Scano G.

J Appl Physiol. 2009 May;106(5):1574-83. Epub 2009 Feb 26.PMID: 19246658 [PubMed - indexed for MEDLINE]Related articles

A controlled trial of 6-weeks' treatment with a novel inhaled phosphodiesterase type-4 inhibitor in COPD.

Vestbo J, Tan L, Atkinson G, Ward J; UK-500,001 Global Study Team.

Eur Respir J. 2009 May;33(5):1039-44. Epub 2009 Feb 12.PMID: 19213793 [PubMed - indexed for MEDLINE]Related articles

Muscle fiber type characteristics in females with chronic obstructive pulmonary disease. A preliminary study.

Green HJ, Burnett ME, D'Arsigny C, Iqbal S, Ouyang J, Webb KA, O'Donnell DE.

J Mol Histol. 2009 Feb;40(1):41-51. Epub 2009 Feb 11.PMID: 19205906 [PubMed - indexed for MEDLINE]Related articles

[Dynamic lung hyperinflation and its clinical implication in COPD]

O'donnell DE.

Rev Mal Respir. 2008 Dec;25(10):1305-18. Review. French. PMID: 19107020 [PubMed - indexed for MEDLINE]Related articles

Evaluation of acute bronchodilator reversibility in patients with symptoms of GOLD stage I COPD.

O'Donnell DE, Laveneziana P, Ora J, Webb KA, Lam YM, Ofir D.

Thorax. 2009 Mar;64(3):216-23. Epub 2008 Dec 3.PMID: 19052054 [PubMed - indexed for MEDLINE]Related articles

Obesity and the lung: 5. Obesity and COPD.

Franssen FM, O'Donnell DE, Goossens GH, Blaak EE, Schols AM.

Thorax. 2008 Dec;63(12):1110-7. Review.PMID: 19020276 [PubMed - indexed for MEDLINE]Related articles

Mechanical ventilatory constraints during incremental cycle exercise in human pregnancy: implications for respiratory sensation.

Jensen D, Webb KA, Davies GA, O'Donnell DE.

J Physiol. 2008 Oct 1;586(Pt 19):4735-50. Epub 2008 Aug 7.PMID: 18687714 [PubMed - indexed for MEDLINE]Related articlesFree article

The major limitation to exercise performance in COPD is dynamic hyperinflation.

O'Donnell DE, Webb KA.

J Appl Physiol. 2008 Aug;105(2):753-5; discussion 755-7. No abstract available. PMID: 18678624 [PubMed - indexed for MEDLINE]Related articlesFree article

Altered metabolic and transporter characteristics of vastus lateralis in chronic obstructive pulmonary disease.

Green HJ, Burnett ME, D'Arsigny CL, O'Donnell DE, Ouyang J, Webb KA.

J Appl Physiol. 2008 Sep;105(3):879-86. Epub 2008 Jul 17.PMID: 18635880 [PubMed - indexed for MEDLINE]Related articlesFree article

Organization of metabolic pathways in vastus lateralis of patients with chronic obstructive pulmonary disease.

Green HJ, Bombardier E, Burnett M, Iqbal S, D'Arsigny CL, O'Donnell DE, Ouyang J, Webb KA.

Am J Physiol Regul Integr Comp Physiol. 2008 Sep;295(3):R935-41. Epub 2008 Jul 16.PMID: 18635455 [PubMed - indexed for MEDLINE]Related articles

Abnormal sarcoplasmic reticulum Ca2+-sequestering properties in skeletal muscle in chronic obstructive pulmonary disease.

Green HJ, Burnett M, Duhamel TA, D'Arsigny C, O'Donnell DE, Webb KA, Ouyang J.

Am J Physiol Cell Physiol. 2008 Aug;295(2):C350-7. Epub 2008 May 28.PMID: 18508908 [PubMed - indexed for MEDLINE]Related articlesFree article

Sex differences in the perceived intensity of breathlessness during exercise with advancing age.

Ofir D, Laveneziana P, Webb KA, Lam YM, O'Donnell DE.

J Appl Physiol. 2008 Jun;104(6):1583-93. Epub 2008 Apr 24.PMID: 18436700 [PubMed - indexed for MEDLINE]Related articlesFree article

Canadian Thoracic Society recommendations for management of chronic obstructive pulmonary disease - 2008 update - highlights for primary care.

O'Donnell DE, Hernandez P, Kaplan A, Aaron S, Bourbeau J, Marciniuk D, Balter M, Ford G, Gervais A, Lacasse Y, Maltais F, Road J, Rocker G, Sin D, Sinuff T, Voduc N.

Can Respir J. 2008 Jan-Feb;15 Suppl A:1A-8A.PMID: 18292855 [PubMed - indexed for MEDLINE]Related articles

Point: Counterpoint - The major limitations to exercise performance in COPD.

Aliverti A Phd, Macklem PT, Debigare R, Maltais F, O'Donnell DE, Webb KA M Sc.

J Appl Physiol. 2008 Mar 13. [Epub ahead of print]PMID: 18339888 [PubMed - as supplied by publisher]Related articles

Physiological mechanisms of hyperventilation during human pregnancy.

Jensen D, Duffin J, Lam YM, Webb KA, Simpson JA, Davies GA, Wolfe LA, O'Donnell DE.

Respir Physiol Neurobiol. 2008 Mar 20;161(1):76-86. Epub 2008 Jan 12.PMID: 18289946 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of dyspnoea relief and improved exercise endurance after furosemide inhalation in COPD.

Jensen D, Amjadi K, Harris-McAllister V, Webb KA, O'Donnell DE.

Thorax. 2008 Jul;63(7):606-13. Epub 2008 Feb 4.PMID: 18250181 [PubMed - indexed for MEDLINE]Related articles

Chemical and mechanical adaptations of the respiratory system at rest and during exercise in human pregnancy.

Jensen D, Webb KA, O'Donnell DE.

Appl Physiol Nutr Metab. 2007 Dec;32(6):1239-50. Review.PMID: 18059602 [PubMed - indexed for MEDLINE]Related articles

Ventilatory constraints and dyspnea during exercise in chronic obstructive pulmonary disease.

Laveneziana P, Parker CM, O'Donnell DE.

Appl Physiol Nutr Metab. 2007 Dec;32(6):1225-38. Review.PMID: 18059601 [PubMed - indexed for MEDLINE]Related articles

Canadian Thoracic Society recommendations for management of chronic obstructive pulmonary disease - 2007 update.

O'Donnell DE, Aaron S, Bourbeau J, Hernandez P, Marciniuk DD, Balter M, Ford G, Gervais A, Goldstein R, Hodder R, Kaplan A, Keenan S, Lacasse Y, Maltais F, Road J, Rocker G, Sin D, Sinuff T, Voduc N.

Can Respir J. 2007 Sep;14 Suppl B:5B-32B. Review.PMID: 17885691 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of dyspnea during cycle exercise in symptomatic patients with GOLD stage I chronic obstructive pulmonary disease.

Ofir D, Laveneziana P, Webb KA, Lam YM, O'Donnell DE.

Am J Respir Crit Care Med. 2008 Mar 15;177(6):622-9. Epub 2007 Nov 15.PMID: 18006885 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms of exertional dyspnea in patients with cancer.

Travers J, Dudgeon DJ, Amjadi K, McBride I, Dillon K, Laveneziana P, Ofir D, Webb KA, O'Donnell DE.

J Appl Physiol. 2008 Jan;104(1):57-66. Epub 2007 Nov 1.PMID: 17975124 [PubMed - indexed for MEDLINE]Related articlesFree article

Dyspnea and activity limitation in COPD: mechanical factors.

O'Donnell DE, Laveneziana P.

COPD. 2007 Sep;4(3):225-36. Review.PMID: 17729066 [PubMed - indexed for MEDLINE]Related articles

Pathophysiology of dyspnea in chronic obstructive pulmonary disease: a roundtable.

O'Donnell DE, Banzett RB, Carrieri-Kohlman V, Casaburi R, Davenport PW, Gandevia SC, Gelb AF, Mahler DA, Webb KA.

Proc Am Thorac Soc. 2007 May;4(2):145-68. Review.PMID: 17494725 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of tiotropium bromide on the cardiovascular response to exercise in COPD.

Travers J, Laveneziana P, Webb KA, Kesten S, O'Donnell DE.

Respir Med. 2007 Sep;101(9):2017-24. Epub 2007 May 1.PMID: 17475459 [PubMed - indexed for MEDLINE]Related articles

The clinical importance of dynamic lung hyperinflation in COPD.

O'Donnell DE, Laveneziana P.

COPD. 2006 Dec;3(4):219-32. Review.PMID: 17361503 [PubMed - indexed for MEDLINE]Related articles

Ventilatory and perceptual responses to cycle exercise in obese women.

Ofir D, Laveneziana P, Webb KA, O'Donnell DE.

J Appl Physiol. 2007 Jun;102(6):2217-26. Epub 2007 Jan 18.PMID: 17234804 [PubMed - indexed for MEDLINE]Related articlesFree article

Recommendations on the use of exercise testing in clinical practice.

ERS Task Force, Palange P, Ward SA, Carlsen KH, Casaburi R, Gallagher CG, Gosselink R, O'Donnell DE, Puente-Maestu L, Schols AM, Singh S, Whipp BJ.

Eur Respir J. 2007 Jan;29(1):185-209. Review.PMID: 17197484 [PubMed - indexed for MEDLINE]Related articlesFree article

Dynamic hyperinflation during bronchoconstriction in asthma: implications for symptom perception.

Lougheed MD, Fisher T, O'Donnell DE.

Chest. 2006 Oct;130(4):1072-81.PMID: 17035440 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscle blood-flow dynamics at exercise onset: do the limbs differ?

Tschakovsky ME, Saunders NR, Webb KA, O'Donnell DE.

Med Sci Sports Exerc. 2006 Oct;38(10):1811-8. Review.PMID: 17019304 [PubMed - indexed for MEDLINE]Related articles

Effects of human pregnancy and advancing gestation on respiratory discomfort during exercise.

Jensen D, Webb KA, Wolfe LA, O'Donnell DE.

Respir Physiol Neurobiol. 2007 Apr 16;156(1):85-93. Epub 2006 Aug 22.PMID: 16996321 [PubMed - indexed for MEDLINE]Related articles

Effect of fluticasone propionate/salmeterol on lung hyperinflation and exercise endurance in COPD.

O'Donnell DE, Sciurba F, Celli B, Mahler DA, Webb KA, Kalberg CJ, Knobil K.

Chest. 2006 Sep;130(3):647-56.PMID: 16963658 [PubMed - indexed for MEDLINE]Related articlesFree article

Sensory-mechanical relationships during high-intensity, constant-work-rate exercise in COPD.

O'Donnell DE, Hamilton AL, Webb KA.

J Appl Physiol. 2006 Oct;101(4):1025-35. Epub 2006 May 4.PMID: 16675610 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperinflation, dyspnea, and exercise intolerance in chronic obstructive pulmonary disease.

O'Donnell DE.

Proc Am Thorac Soc. 2006 Apr;3(2):180-4. Review.PMID: 16565429 [PubMed - indexed for MEDLINE]Related articlesFree article

COPD exacerbations . 3: Pathophysiology.

O'Donnell DE, Parker CM.

Thorax. 2006 Apr;61(4):354-61. Review.PMID: 16565268 [PubMed - indexed for MEDLINE]Related articlesFree article

Is sustained pharmacologic lung volume reduction now possible in COPD?

O'Donnell DE.

Chest. 2006 Mar;129(3):501-3. No abstract available. PMID: 16537841 [PubMed - indexed for MEDLINE]Related articlesFree article

Combined physiological effects of bronchodilators and hyperoxia on exertional dyspnoea in normoxic COPD.

Peters MM, Webb KA, O'Donnell DE.

Thorax. 2006 Jul;61(7):559-67. Epub 2006 Feb 7.PMID: 16467067 [PubMed - indexed for MEDLINE]Related articlesFree article

Physiological changes during symptom recovery from moderate exacerbations of COPD.

Parker CM, Voduc N, Aaron SD, Webb KA, O'Donnell DE.

Eur Respir J. 2005 Sep;26(3):420-8.PMID: 16135722 [PubMed - indexed for MEDLINE]Related articlesFree article