PubMed

Phase II Trial of Temozolomide and Sorafenib in Advanced Melanoma Patients with or without Brain Metastases.

Amaravadi RK, Schuchter LM, McDermott DF, Kramer A, Giles L, Gramlich K, Carberry M, Troxel AB, Letrero R, Nathanson KL, Atkins MB, O'Dwyer PJ, Flaherty KT.

Clin Cancer Res. 2009 Dec 15;15(24):7711-7718. Epub .PMID: 19996224 [PubMed - as supplied by publisher]Related articles

A risk variant in an miR-125b binding site in BMPR1B is associated with breast cancer pathogenesis.

Saetrom P, Biesinger J, Li SM, Smith D, Thomas LF, Majzoub K, Rivas GE, Alluin J, Rossi JJ, Krontiris TG, Weitzel J, Daly MB, Benson AB, Kirkwood JM, O'Dwyer PJ, Sutphen R, Stewart JA, Johnson D, Larson GP.

Cancer Res. 2009 Sep 15;69(18):7459-65. Epub 2009 Sep 8.PMID: 19738052 [PubMed - indexed for MEDLINE]Related articles

Pharmacokinetic analysis of irinotecan plus bevacizumab in patients with advanced solid tumors.

Denlinger CS, Blanchard R, Xu L, Bernaards C, Litwin S, Spittle C, Berg DJ, McLaughlin S, Redlinger M, Dorr A, Hambleton J, Holden S, Kearns A, Kenkare-Mitra S, Lum B, Meropol NJ, O'Dwyer PJ.

Cancer Chemother Pharmacol. 2009 Dec;65(1):97-105. Epub 2009 May 5.PMID: 19415281 [PubMed - indexed for MEDLINE]Related articles

The terrible choice: re-evaluating hospice eligibility criteria for cancer.

Casarett DJ, Fishman JM, Lu HL, O'Dwyer PJ, Barg FK, Naylor MD, Asch DA.

J Clin Oncol. 2009 Feb 20;27(6):953-9. Epub 2008 Dec 29.PMID: 19114698 [PubMed - indexed for MEDLINE]Related articlesFree article

Do phase 1 patients have greater needs for palliative care compared with other cancer patients?

Finlay E, Lu HL, Henderson H, O'Dwyer PJ, Casarett DJ.

Cancer. 2009 Jan 15;115(2):446-53.PMID: 19107769 [PubMed - indexed for MEDLINE]Related articles

Strong signature of natural selection within an FHIT intron implicated in prostate cancer risk.

Ding Y, Larson G, Rivas G, Lundberg C, Geller L, Ouyang C, Weitzel J, Archambeau J, Slater J, Daly MB, Benson AB, Kirkwood JM, O'Dwyer PJ, Sutphen R, Stewart JA, Johnson D, Nordborg M, Krontiris TG.

PLoS One. 2008;3(10):e3533. Epub 2008 Oct 27.PMID: 18953408 [PubMed - indexed for MEDLINE]Related articlesFree article

Experience in identifying the venous drainage of the adrenal gland during laparoscopic adrenalectomy.

Parnaby CN, Galbraith N, O'Dwyer PJ.

Clin Anat. 2008 Oct;21(7):660-5.PMID: 18816449 [PubMed - indexed for MEDLINE]Related articles

The measurement of chronic pain and health-related quality of life following inguinal hernia repair: a review of the literature.

van Hanswijck de Jonge P, Lloyd A, Horsfall L, Tan R, O'Dwyer PJ.

Hernia. 2008 Dec;12(6):561-9. Epub 2008 Aug 21. Review.PMID: 18716856 [PubMed - indexed for MEDLINE]Related articles

A phase I trial of the oral, multikinase inhibitor sorafenib in combination with carboplatin and paclitaxel.

Flaherty KT, Schiller J, Schuchter LM, Liu G, Tuveson DA, Redlinger M, Lathia C, Xia C, Petrenciuc O, Hingorani SR, Jacobetz MA, Van Belle PA, Elder D, Brose MS, Weber BL, Albertini MR, O'Dwyer PJ.

Clin Cancer Res. 2008 Aug 1;14(15):4836-42.PMID: 18676756 [PubMed - indexed for MEDLINE]Related articlesFree article

Early discharge following liver resection for colorectal metastases.

MacKay G, O'Dwyer PJ.

Scott Med J. 2008 May;53(2):22-4.PMID: 18549066 [PubMed - indexed for MEDLINE]Related articles

Phase II trial of sorafenib in advanced thyroid cancer.

Gupta-Abramson V, Troxel AB, Nellore A, Puttaswamy K, Redlinger M, Ransone K, Mandel SJ, Flaherty KT, Loevner LA, O'Dwyer PJ, Brose MS.

J Clin Oncol. 2008 Oct 10;26(29):4714-9. Epub 2008 Jun 9.PMID: 18541894 [PubMed - indexed for MEDLINE]Related articlesFree article

Disruption of signaling through SEK1 and MKK7 yields differential responses in hypoxic colon cancer cells treated with oxaliplatin.

Vasilevskaya IA, Selvakumaran M, O'Dwyer PJ.

Mol Pharmacol. 2008 Jul;74(1):246-54. Epub 2008 Apr 24.PMID: 18436711 [PubMed - indexed for MEDLINE]Related articlesFree article

How should we design supportive cancer care? The patient's perspective.

Casarett D, Fishman J, O'Dwyer PJ, Barg FK, Naylor M, Asch DA.

J Clin Oncol. 2008 Mar 10;26(8):1296-301.PMID: 18323553 [PubMed - indexed for MEDLINE]Related articles

Inguinal hernias.

Jenkins JT, O'Dwyer PJ.

BMJ. 2008 Feb 2;336(7638):269-72. Review. No abstract available. PMID: 18244999 [PubMed - indexed for MEDLINE]Related articles

Pilot study of DCE-MRI to predict progression-free survival with sorafenib therapy in renal cell carcinoma.

Flaherty KT, Rosen MA, Heitjan DF, Gallagher ML, Schwartz B, Schnall MD, O'Dwyer PJ.

Cancer Biol Ther. 2008 Apr;7(4):496-501. Epub 2008 Jan 22.PMID: 18219225 [PubMed - indexed for MEDLINE]Related articlesFree article

Antitumor effect of the angiogenesis inhibitor bevacizumab is dependent on susceptibility of tumors to hypoxia-induced apoptosis.

Selvakumaran M, Yao KS, Feldman MD, O'Dwyer PJ.

Biochem Pharmacol. 2008 Feb 1;75(3):627-38. Epub 2007 Oct 11.PMID: 18178171 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of laparoscopic adrenalectomy for adrenal tumours of 6 cm or greater.

Parnaby CN, Chong PS, Chisholm L, Farrow J, Connell JM, O'Dwyer PJ.

Surg Endosc. 2008 Mar;22(3):617-21. Epub 2007 Dec 11.PMID: 18071798 [PubMed - indexed for MEDLINE]Related articles

A phase I and pharmacokinetic study of lapatinib in combination with infusional 5-fluorouracil, leucovorin and irinotecan.

Midgley RS, Kerr DJ, Flaherty KT, Stevenson JP, Pratap SE, Koch KM, Smith DA, Versola M, Fleming RA, Ward C, O'Dwyer PJ, Middleton MR.

Ann Oncol. 2007 Dec;18(12):2025-9. Epub 2007 Sep 9.PMID: 17846021 [PubMed - indexed for MEDLINE]Related articlesFree article

Laparoscopic colorectal resection does not reduce incisional hernia rates when compared with open colorectal resection.

Ihedioha U, Mackay G, Leung E, Molloy RG, O'Dwyer PJ.

Surg Endosc. 2008 Mar;22(3):689-92.PMID: 17623241 [PubMed - indexed for MEDLINE]Related articles

Priorities in colorectal cancer research: recommendations from the Gastrointestinal Scientific Leadership Council of the Coalition of Cancer Cooperative Groups.

O'Dwyer PJ, Eckhardt SG, Haller DG, Tepper J, Ahnen D, Hamilton S, Benson AB 3rd, Rothenberg M, Petrelli N, Lenz HJ, Diasio R, DuBois R, Sargent D, Sloan J, Johnson CD, Comis RL, O'Connell MJ; Gastrointestinal Scientific Leadership Council of the Coalition of Cancer Cooperative Groups.

J Clin Oncol. 2007 Jun 1;25(16):2313-21. Review.PMID: 17538178 [PubMed - indexed for MEDLINE]Related articles

Treatment of asymptomatic inguinal hernias.

Chung L, O'Dwyer PJ.

Surgeon. 2007 Apr;5(2):95-100; quiz 100, 121. Review.PMID: 17450691 [PubMed - indexed for MEDLINE]Related articles

Effect of time interval between surgery and preoperative chemoradiotherapy with 5-fluorouracil or 5-fluorouracil and oxaliplatin on outcomes in rectal cancer.

Dolinsky CM, Mahmoud NN, Mick R, Sun W, Whittington RW, Solin LJ, Haller DG, Giantonio BJ, O'Dwyer PJ, Rosato EF, Fry RD, Metz JM.

J Surg Oncol. 2007 Sep 1;96(3):207-12.PMID: 17443718 [PubMed - indexed for MEDLINE]Related articles

Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200.

Giantonio BJ, Catalano PJ, Meropol NJ, O'Dwyer PJ, Mitchell EP, Alberts SR, Schwartz MA, Benson AB 3rd; Eastern Cooperative Oncology Group Study E3200.

J Clin Oncol. 2007 Apr 20;25(12):1539-44.PMID: 17442997 [PubMed - indexed for MEDLINE]Related articles

Laparoscopic colonic resection in fast-track patients does not enhance short-term recovery after elective surgery.

MacKay G, Ihedioha U, McConnachie A, Serpell M, Molloy RG, O'Dwyer PJ.

Colorectal Dis. 2007 May;9(4):368-72.PMID: 17432992 [PubMed - indexed for MEDLINE]Related articles

Prospective, five-year follow-up study of patients with symptomatic uncomplicated diverticular disease.

Salem TA, Molloy RG, O'Dwyer PJ.

Dis Colon Rectum. 2007 Sep;50(9):1460-4.PMID: 17431721 [PubMed - indexed for MEDLINE]Related articles

Prospective study on the role of C-reactive protein (CRP) in patients with an acute abdomen.

Salem TA, Molloy RG, O'Dwyer PJ.

Ann R Coll Surg Engl. 2007 Apr;89(3):233-7.PMID: 17394705 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of G1/S transition potentiates oxaliplatin-induced cell death in colon cancer cell lines.

Rakitina TV, Vasilevskaya IA, O'Dwyer PJ.

Biochem Pharmacol. 2007 Jun 1;73(11):1715-26. Epub 2007 Feb 4.PMID: 17343830 [PubMed - indexed for MEDLINE]Related articles

Clinical activity and immune modulation in cancer patients treated with CP-870,893, a novel CD40 agonist monoclonal antibody.

Vonderheide RH, Flaherty KT, Khalil M, Stumacher MS, Bajor DL, Hutnick NA, Sullivan P, Mahany JJ, Gallagher M, Kramer A, Green SJ, O'Dwyer PJ, Running KL, Huhn RD, Antonia SJ.

J Clin Oncol. 2007 Mar 1;25(7):876-83.PMID: 17327609 [PubMed - indexed for MEDLINE]Related articles

Differential gene expression patterns and interaction networks in BCR-ABL-positive and -negative adult acute lymphoblastic leukemias.

Juric D, Lacayo NJ, Ramsey MC, Racevskis J, Wiernik PH, Rowe JM, Goldstone AH, O'Dwyer PJ, Paietta E, Sikic BI.

J Clin Oncol. 2007 Apr 10;25(11):1341-9. Epub 2007 Feb 20.PMID: 17312329 [PubMed - indexed for MEDLINE]Related articles

Watchful waiting was as safe as surgical repair for minimally symptomatic inguinal hernias.

O'Dwyer PJ, Chung L.

Evid Based Med. 2006 Jun;11(3):73. No abstract available. PMID: 17213095 [PubMed]Related articles

Malignant disease in peptic ulcer surgery patients after long term follow-up: a cohort study of 1992 patients.

Jenkins JT, Duncan JR, Hole D, O'Dwyer PJ, McGregor JR.

Eur J Surg Oncol. 2007 Aug;33(6):706-12. Epub 2007 Jan 5.PMID: 17207958 [PubMed - indexed for MEDLINE]Related articles

Randomized clinical trial of the effect of postoperative intravenous fluid restriction on recovery after elective colorectal surgery.

MacKay G, Fearon K, McConnachie A, Serpell MG, Molloy RG, O'Dwyer PJ.

Br J Surg. 2006 Dec;93(12):1469-74.PMID: 17078116 [PubMed - indexed for MEDLINE]Related articles

The present and future of angiogenesis-directed treatments of colorectal cancer.

O'Dwyer PJ.

Oncologist. 2006 Oct;11(9):992-8. Review.PMID: 17030640 [PubMed - indexed for MEDLINE]Related articlesFree article

A complex fistula caused by an eroding pelvic mesh sling.

Ihedioha U, Leung E, Chung L, Burgess G, Hendry D, O'dwyer PJ.

Hernia. 2007 Feb;11(1):75-8. Epub 2006 Sep 23.PMID: 17024307 [PubMed - indexed for MEDLINE]Related articles

Uridine diphosphate glucuronosyltransferase (UGT) 1A1 and irinotecan: practical pharmacogenomics arrives in cancer therapy.

O'Dwyer PJ, Catalano RB.

J Clin Oncol. 2006 Oct 1;24(28):4534-8. Review. No abstract available. PMID: 17008691 [PubMed - indexed for MEDLINE]Related articles

Gene expression profiling of human ovarian tumours.

Biade S, Marinucci M, Schick J, Roberts D, Workman G, Sage EH, O'Dwyer PJ, Livolsi VA, Johnson SW.

Br J Cancer. 2006 Oct 23;95(8):1092-100. Epub 2006 Sep 12.PMID: 16969345 [PubMed - indexed for MEDLINE]Related articlesFree article

Sorafenib in advanced melanoma: a Phase II randomised discontinuation trial analysis.

Eisen T, Ahmad T, Flaherty KT, Gore M, Kaye S, Marais R, Gibbens I, Hackett S, James M, Schuchter LM, Nathanson KL, Xia C, Simantov R, Schwartz B, Poulin-Costello M, O'Dwyer PJ, Ratain MJ.

Br J Cancer. 2006 Sep 4;95(5):581-6. Epub 2006 Aug 1.PMID: 16880785 [PubMed - indexed for MEDLINE]Related articlesFree article

A phase II study of high-dose bevacizumab in combination with irinotecan, 5-fluorouracil, leucovorin, as initial therapy for advanced colorectal cancer: results from the Eastern Cooperative Oncology Group study E2200.

Giantonio BJ, Levy DE, O'dwyer PJ, Meropol NJ, Catalano PJ, Benson AB 3rd; Eastern Cooperative Oncology Group.

Ann Oncol. 2006 Sep;17(9):1399-403. Epub 2006 Jul 27.PMID: 16873427 [PubMed - indexed for MEDLINE]Related articlesFree article

Observation or operation for patients with an asymptomatic inguinal hernia: a randomized clinical trial.

O'Dwyer PJ, Norrie J, Alani A, Walker A, Duffy F, Horgan P.

Ann Surg. 2006 Aug;244(2):167-73.PMID: 16858177 [PubMed - indexed for MEDLINE]Related articlesFree article

Hernias are the most common cause of strangulation in patients presenting with small bowel obstruction.

Ihedioha U, Alani A, Modak P, Chong P, O'Dwyer PJ.

Hernia. 2006 Aug;10(4):338-40. Epub 2006 Jun 8.PMID: 16761112 [PubMed - indexed for MEDLINE]Related articles

Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma.

Ratain MJ, Eisen T, Stadler WM, Flaherty KT, Kaye SB, Rosner GL, Gore M, Desai AA, Patnaik A, Xiong HQ, Rowinsky E, Abbruzzese JL, Xia C, Simantov R, Schwartz B, O'Dwyer PJ.

J Clin Oncol. 2006 Jun 1;24(16):2505-12. Epub 2006 Apr 24.PMID: 16636341 [PubMed - indexed for MEDLINE]Related articles

Value of biopsy in the assessment of a retroperitoneal mass.

Chew C, Reid R, O'Dwyer PJ.

Surgeon. 2006 Apr;4(2):79-81.PMID: 16623162 [PubMed - indexed for MEDLINE]Related articles

Is pre-operative radiotherapy necessary in T-T rectal cancer with TME?

Mackay G, Downey M, Molloy RG, O'Dwyer PJ.

Colorectal Dis. 2006 Jan;8(1):34-6.PMID: 16519635 [PubMed - indexed for MEDLINE]Related articles

Prospective study on the management of patients with complicated diverticular disease.

Salem TA, Molloy RG, O'Dwyer PJ.

Colorectal Dis. 2006 Mar;8(3):173-6.PMID: 16466555 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of hypertension associated with BAY 43-9006.

Veronese ML, Mosenkis A, Flaherty KT, Gallagher M, Stevenson JP, Townsend RR, O'Dwyer PJ.

J Clin Oncol. 2006 Mar 20;24(9):1363-9. Epub 2006 Jan 30.PMID: 16446323 [PubMed - indexed for MEDLINE]Related articles

Laparoscopic or open preperitoneal repair in the management of recurrent groin hernias.

Alani A, Duffy F, O'Dwyer PJ.

Hernia. 2006 Apr;10(2):156-8. Epub 2005 Dec 9.PMID: 16341624 [PubMed - indexed for MEDLINE]Related articles

In vitro hypoxia-conditioned colon cancer cell lines derived from HCT116 and HT29 exhibit altered apoptosis susceptibility and a more angiogenic profile in vivo.

Yao K, Gietema JA, Shida S, Selvakumaran M, Fonrose X, Haas NB, Testa J, O'Dwyer PJ.

Br J Cancer. 2005 Dec 12;93(12):1356-63.PMID: 16333244 [PubMed - indexed for MEDLINE]Related articlesFree article

Prospective study on the presentation and outcome of patients with an acute hernia.

Alani A, Page B, O'Dwyer PJ.

Hernia. 2006 Mar;10(1):62-5. Epub 2005 Nov 5.PMID: 16273307 [PubMed - indexed for MEDLINE]Related articles

Macrophage migration inhibitory factor is a determinant of hypoxia-induced apoptosis in colon cancer cell lines.

Yao K, Shida S, Selvakumaran M, Zimmerman R, Simon E, Schick J, Haas NB, Balke M, Ross H, Johnson SW, O'Dwyer PJ.

Clin Cancer Res. 2005 Oct 15;11(20):7264-72.PMID: 16243796 [PubMed - indexed for MEDLINE]Related articlesFree article

A technically difficult endorectal ultrasound is more likely to be inaccurate.

Zammit M, Jenkins JT, Urie A, O'Dwyer PJ, Molloy RG.

Colorectal Dis. 2005 Sep;7(5):486-91.PMID: 16108886 [PubMed - indexed for MEDLINE]Related articles