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    Results: 1 to 50 of 59

    1.

    Impact of human immunodeficiency virus type 1 reverse transcriptase inhibitor drug resistance mutation interactions on phenotypic susceptibility.

    Trivedi V, Von Lindern J, Montes-Walters M, Rojo DR, Shell EJ, Parkin N, O'Brien WA, Ferguson MR.

    AIDS Res Hum Retroviruses. 2008 Oct;24(10):1291-300.PMID: 18844463 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    A critical role for CD63 in HIV replication and infection of macrophages and cell lines.

    Chen H, Dziuba N, Friedrich B, von Lindern J, Murray JL, Rojo DR, Hodge TW, O'Brien WA, Ferguson MR.

    Virology. 2008 Sep 30;379(2):191-6. Epub 2008 Aug 5.PMID: 18682304 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Evolution of HIV resistance mutations in patients maintained on a stable treatment regimen after virologic failure.

    Goetz MB, Ferguson MR, Han X, McMillan G, St Clair M, Pappa KA, McClernon DR, O'Brien WA.

    J Acquir Immune Defic Syndr. 2006 Dec 15;43(5):541-9.PMID: 17075391 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Saquinavir/Ritonavir: its evolution and current treatment role.

    O'Brien WA 3rd.

    AIDS Read. 2006 Jan;16(1):38-44; discussion 43. Review.PMID: 16433471 [PubMed - indexed for MEDLINE]Related articles

    5.

    Combinatorial selection, inhibition, and antiviral activity of DNA thioaptamers targeting the RNase H domain of HIV-1 reverse transcriptase.

    Somasunderam A, Ferguson MR, Rojo DR, Thiviyanathan V, Li X, O'Brien WA, Gorenstein DG.

    Biochemistry. 2005 Aug 2;44(30):10388-95.PMID: 16042416 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Specificity of the antibody response to the pneumococcal polysaccharide and conjugate vaccines in human immunodeficiency virus-infected adults.

    Feikin DR, Elie CM, Goetz MB, Lennox JL, Carlone GM, Romero-Steiner S, Holder PF, O'Brien WA, Whitney CG, Butler JC, Breiman RF.

    Clin Diagn Lab Immunol. 2004 Jan;11(1):137-41.PMID: 14715560 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    New classes of HIV drugs on the horizon. A review of the presentation at the satellite symposium "New hope: advancing care in HIV infection" at the 15th annual Association of Nurses in AIDS Care conference, November 2002.

    O'Brien WA.

    AIDS Read. 2003 Mar;13(3 Suppl):S4-8. Review.PMID: 12765159 [PubMed - indexed for MEDLINE]Related articles

    8.

    Potential role for CD63 in CCR5-mediated human immunodeficiency virus type 1 infection of macrophages.

    von Lindern JJ, Rojo D, Grovit-Ferbas K, Yeramian C, Deng C, Herbein G, Ferguson MR, Pappas TC, Decker JM, Singh A, Collman RG, O'Brien WA.

    J Virol. 2003 Mar;77(6):3624-33.PMID: 12610138 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Special issues in the management of patients with ESRD and HIV infection.

    Ahuja TS, O'brien WA.

    Am J Kidney Dis. 2003 Feb;41(2):279-91. Review.PMID: 12552489 [PubMed - indexed for MEDLINE]Related articles

    10.

    HIV-1 replication cycle.

    Ferguson MR, Rojo DR, von Lindern JJ, O'Brien WA.

    Clin Lab Med. 2002 Sep;22(3):611-35. Review.PMID: 12244589 [PubMed - indexed for MEDLINE]Related articles

    11.

    Viral load response to a pneumococcal conjugate vaccine, polysaccharide vaccine or placebo among HIV-infected patients.

    Goetz MB, Feikin DR, Lennox JL, O'Brien WA, Elie CM, Butler JC, Breiman RF.

    AIDS. 2002 Jul 5;16(10):1421-3.PMID: 12131220 [PubMed - indexed for MEDLINE]Related articles

    12.

    Genotypic HIV-1 drug resistance testing in antiretroviral-naive subjects in Houston, Texas.

    Nannini EC, Han X, O'Brien WA, Arduino RC.

    J Acquir Immune Defic Syndr. 2002 Mar 1;29(3):317-9. No abstract available. PMID: 11873085 [PubMed - indexed for MEDLINE]Related articles

    13.

    Randomized trial of the quantitative and functional antibody responses to a 7-valent pneumococcal conjugate vaccine and/or 23-valent polysaccharide vaccine among HIV-infected adults.

    Feikin DR, Elie CM, Goetz MB, Lennox JL, Carlone GM, Romero-Steiner S, Holder PF, O'Brien WA, Whitney CG, Butler JC, Breiman RF.

    Vaccine. 2001 Nov 12;20(3-4):545-53.PMID: 11672921 [PubMed - indexed for MEDLINE]Related articles

    14.

    Sensitivity of human immunodeficiency virus type 1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptor.

    Derdeyn CA, Decker JM, Sfakianos JN, Zhang Z, O'Brien WA, Ratner L, Shaw GM, Hunter E.

    J Virol. 2001 Sep;75(18):8605-14.PMID: 11507206 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Resistance to apoptosis in HIV-infected CD4+ T lymphocytes is mediated by macrophages: role for Nef and immune activation in viral persistence.

    Mahlknecht U, Deng C, Lu MC, Greenough TC, Sullivan JL, O'Brien WA, Herbein G.

    J Immunol. 2000 Dec 1;165(11):6437-46.PMID: 11086083 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Comparison of immunologic restoration and virologic response in plasma, tonsillar tissue, and cerebrospinal fluid in HIV-1-infected patients treated with double versus triple antiretroviral therapy in very early stages: The Spanish EARTH-2 Study. Early Anti-Retroviral Therapy Study.

    García F, Alonso MM, Romeu J, Knobel H, Arrizabalaga J, Ferrer E, Dalmau D, Ruiz I, Vidal F, Frances A, Segura F, Gomez-Sirvent JL, Cruceta A, Clotet B, Pumarola T, Gallart T, O'Brien WA, Miró JM, Gatell JM.

    J Acquir Immune Defic Syndr. 2000 Sep 1;25(1):26-35.PMID: 11064501 [PubMed - indexed for MEDLINE]Related articles

    17.

    Sensitivity of human immunodeficiency virus type 1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120.

    Derdeyn CA, Decker JM, Sfakianos JN, Wu X, O'Brien WA, Ratner L, Kappes JC, Shaw GM, Hunter E.

    J Virol. 2000 Sep;74(18):8358-67.PMID: 10954535 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Resistance against reverse transcriptase inhibitors.

    O'Brien WA.

    Clin Infect Dis. 2000 Jun;30 Suppl 2:S185-92. Review.PMID: 10860904 [PubMed - indexed for MEDLINE]Related articles

    19.

    Tumor necrosis factor (TNF)-alpha and TNF receptors in viral pathogenesis.

    Herbein G, O'Brien WA.

    Proc Soc Exp Biol Med. 2000 Mar;223(3):241-57. Review.PMID: 10719836 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    A randomized study comparing triple versus double antiretroviral therapy or no treatment in HIV-1-infected patients in very early stage disease: the Spanish Earth-1 study.

    García F, Romeu J, Grau I, Sambeat MA, Dalmau D, Knobel H, Gomez-Sirvent JL, Arrizabalaga J, Cruceta A, Clotet BG, Podzamczer D, Pumarola T, Gallart T, O'Brien WA, Miró JM, Gatell JM.

    AIDS. 1999 Dec 3;13(17):2377-88.PMID: 10597779 [PubMed - indexed for MEDLINE]Related articles

    21.

    Dynamics of viral load rebound and immunological changes after stopping effective antiretroviral therapy.

    García F, Plana M, Vidal C, Cruceta A, O'Brien WA, Pantaleo G, Pumarola T, Gallart T, Miró JM, Gatell JM.

    AIDS. 1999 Jul 30;13(11):F79-86.PMID: 10449278 [PubMed - indexed for MEDLINE]Related articles

    22.

    Determinant in human immunodeficiency virus type 1 for efficient replication under cytokine-induced CD4(+) T-helper 1 (Th1)- and Th2-type conditions.

    Suzuki Y, Koyanagi Y, Tanaka Y, Murakami T, Misawa N, Maeda N, Kimura T, Shida H, Hoxie JA, O'Brien WA, Yamamoto N.

    J Virol. 1999 Jan;73(1):316-24.PMID: 9847335 [PubMed - indexed for MEDLINE]Related articlesFree article

    23.

    Natural killer cells from HIV-1+ patients produce C-C chemokines and inhibit HIV-1 infection.

    Fehniger TA, Herbein G, Yu H, Para MI, Bernstein ZP, O'Brien WA, Caligiuri MA.

    J Immunol. 1998 Dec 1;161(11):6433-8.PMID: 9834136 [PubMed - indexed for MEDLINE]Related articlesFree article

    24.

    Effect of oral beta-carotene supplementation on plasma human immunodeficiency virus (HIV) RNA levels and CD4+ cell counts in HIV-infected patients.

    Nimmagadda AP, Burri BJ, Neidlinger T, O'Brien WA, Goetz MB.

    Clin Infect Dis. 1998 Nov;27(5):1311-3.PMID: 9827288 [PubMed - indexed for MEDLINE]Related articles

    25.

    Potential contributions of viral envelope and host genetic factors in a human immunodeficiency virus type 1-infected long-term survivor.

    Grovit-Ferbas K, Ferbas J, Gudeman V, Sadeghi S, Goetz MB, Giorgi JV, Chen IS, O'Brien WA.

    J Virol. 1998 Nov;72(11):8650-8.PMID: 9765405 [PubMed - indexed for MEDLINE]Related articlesFree article

    26.

    Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4.

    Herbein G, Mahlknecht U, Batliwalla F, Gregersen P, Pappas T, Butler J, O'Brien WA, Verdin E.

    Nature. 1998 Sep 10;395(6698):189-94.PMID: 9744279 [PubMed - indexed for MEDLINE]Related articles

    27.

    Effects of influenza vaccination in HIV-infected adults: a double-blind, placebo-controlled trial.

    Tasker SA, O'Brien WA, Treanor JJ, Weiss PJ, Olson PE, Kaplan AH, Wallace MR.

    Vaccine. 1998 May-Jun;16(9-10):1039-42.PMID: 9682356 [PubMed - indexed for MEDLINE]Related articles

    28.

    Impact on the immune system of undetectable plasma HIV-1 RNA for more than 2 years.

    Arnó A, Ruiz L, Juan M, Zayat MK, Puig T, Balagué M, Romeu J, Pujol R, O'Brien WA, Clotet B.

    AIDS. 1998 May 7;12(7):697-704.PMID: 9619800 [PubMed - indexed for MEDLINE]Related articles

    29.

    The significance of vitamin A and carotenoid status in persons infected by the human immunodeficiency virus.

    Nimmagadda A, O'Brien WA, Goetz MB.

    Clin Infect Dis. 1998 Mar;26(3):711-8. Review.PMID: 9524850 [PubMed - indexed for MEDLINE]Related articles

    30.

    The effect of exercise training on aerobic fitness, immune indices, and quality of life in HIV+ patients.

    Stringer WW, Berezovskaya M, O'Brien WA, Beck CK, Casaburi R.

    Med Sci Sports Exerc. 1998 Jan;30(1):11-6.PMID: 9475639 [PubMed - indexed for MEDLINE]Related articles

    31.

    A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor.

    Doranz BJ, Grovit-Ferbas K, Sharron MP, Mao SH, Goetz MB, Daar ES, Doms RW, O'Brien WA.

    J Exp Med. 1997 Oct 20;186(8):1395-400.PMID: 9334380 [PubMed - indexed for MEDLINE]Related articlesFree article

    32.

    Changes in plasma HIV RNA levels and CD4+ lymphocyte counts predict both response to antiretroviral therapy and therapeutic failure. VA Cooperative Study Group on AIDS.

    O'Brien WA, Hartigan PM, Daar ES, Simberkoff MS, Hamilton JD.

    Ann Intern Med. 1997 Jun 15;126(12):939-45.PMID: 9182470 [PubMed - indexed for MEDLINE]Related articlesFree article

    33.

    Human immunodeficiency virus type 1 activation after blood transfusion.

    Mudido PM, Georges D, Dorazio D, Yen-Lieberman B, Bae S, O'Brien WA, Spritzler J, Lederman MM.

    Transfusion. 1996 Oct;36(10):860-5.PMID: 8863771 [PubMed - indexed for MEDLINE]Related articles

    34.

    HIV viral load markers in clinical practice.

    Saag MS, Holodniy M, Kuritzkes DR, O'Brien WA, Coombs R, Poscher ME, Jacobsen DM, Shaw GM, Richman DD, Volberding PA.

    Nat Med. 1996 Jun;2(6):625-9. Review.PMID: 8640545 [PubMed - indexed for MEDLINE]Related articles

    35.

    Anti-human immunodeficiency virus type 1 activity of an oligocationic compound mediated via gp120 V3 interactions.

    O'Brien WA, Sumner-Smith M, Mao SH, Sadeghi S, Zhao JQ, Chen IS.

    J Virol. 1996 May;70(5):2825-31.PMID: 8627756 [PubMed - indexed for MEDLINE]Related articlesFree article

    36.

    Changes in plasma HIV-1 RNA and CD4+ lymphocyte counts and the risk of progression to AIDS. Veterans Affairs Cooperative Study Group on AIDS.

    O'Brien WA, Hartigan PM, Martin D, Esinhart J, Hill A, Benoit S, Rubin M, Simberkoff MS, Hamilton JD.

    N Engl J Med. 1996 Feb 15;334(7):426-31.PMID: 8552144 [PubMed - indexed for MEDLINE]Related articlesFree article

    37.

    Long-term follow-up of symptomatic HIV-infected patients originally randomized to early versus later zidovudine treatment; report of a Veterans Affairs Cooperative Study. VA Cooperative Study Group on AIDS Treatment.

    Simberkoff MS, Hartigan PM, Hamilton JD, Day PL, Diamond GR, Dickinson GM, Drusano GL, Egorin MJ, George WL, Gordin FM, Hawkes CA, Jensen PC, Kilmas NG, Labriola AM, O'Brien WA, Oster CN, Weinhold KJ, Wray NP, Pazner SB.

    J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Feb 1;11(2):142-50.PMID: 8556396 [PubMed - indexed for MEDLINE]Related articles

    38.

    Human immunodeficiency virus-type 1 replication can be increased in peripheral blood of seropositive patients after influenza vaccination.

    O'Brien WA, Grovit-Ferbas K, Namazi A, Ovcak-Derzic S, Wang HJ, Park J, Yeramian C, Mao SH, Zack JA.

    Blood. 1995 Aug 1;86(3):1082-9.PMID: 7620162 [PubMed - indexed for MEDLINE]Related articlesFree article

    39.

    HIV-1 entry and reverse transcription in macrophages.

    O'Brien WA.

    J Leukoc Biol. 1994 Sep;56(3):273-7. Review.PMID: 8083599 [PubMed - indexed for MEDLINE]Related articlesFree article

    40.

    Macrophage-tropic and T-cell line-adapted chimeric strains of human immunodeficiency virus type 1 differ in their susceptibilities to neutralization by soluble CD4 at different temperatures.

    O'Brien WA, Mao SH, Cao Y, Moore JP.

    J Virol. 1994 Aug;68(8):5264-9.PMID: 8035523 [PubMed - indexed for MEDLINE]Related articlesFree article

    41.

    Kinetics of human immunodeficiency virus type 1 reverse transcription in blood mononuclear phagocytes are slowed by limitations of nucleotide precursors.

    O'Brien WA, Namazi A, Kalhor H, Mao SH, Zack JA, Chen IS.

    J Virol. 1994 Feb;68(2):1258-63.PMID: 7507180 [PubMed - indexed for MEDLINE]Related articlesFree article

    42.

    Genetic and biologic basis of HIV-1 neurotropism.

    O'Brien WA.

    Res Publ Assoc Res Nerv Ment Dis. 1994;72:47-70. Review. No abstract available. PMID: 8115721 [PubMed - indexed for MEDLINE]Related articles

    43.

    Rapid enzymatic analysis for human immunodeficiency virus type 1 DNA in clinical specimens.

    Sevall JS, Prince H, Garratty G, O'Brien WA, Zack JA.

    Clin Chem. 1993 Mar;39(3):433-9.PMID: 8448853 [PubMed - indexed for MEDLINE]Related articlesFree article

    44.

    Mapping genetic determinants for human immunodeficiency virus type 1 resistance to soluble CD4.

    O'Brien WA, Chen IS, Ho DD, Daar ES.

    J Virol. 1992 May;66(5):3125-30.PMID: 1373203 [PubMed - indexed for MEDLINE]Related articlesFree article

    45.

    Human immunodeficiency virus type 1 tropism for brain microglial cells is determined by a region of the env glycoprotein that also controls macrophage tropism.

    Sharpless NE, O'Brien WA, Verdin E, Kufta CV, Chen IS, Dubois-Dalcq M.

    J Virol. 1992 Apr;66(4):2588-93.PMID: 1548785 [PubMed - indexed for MEDLINE]Related articlesFree article

    46.

    Viral determinants of cellular tropism.

    O'Brien WA.

    Pathobiology. 1992;60(4):225-33. Review.PMID: 1388720 [PubMed - indexed for MEDLINE]Related articles

    47.

    Increased susceptibility of differentiated mononuclear phagocytes to productive infection with human immunodeficiency virus-1 (HIV-1).

    Rich EA, Chen IS, Zack JA, Leonard ML, O'Brien WA.

    J Clin Invest. 1992 Jan;89(1):176-83.PMID: 1370293 [PubMed - indexed for MEDLINE]Related articlesFree article

    48.

    HIV-1 env sequence variation in brain tissue of patients with AIDS-related neurologic disease.

    Pang S, Vinters HV, Akashi T, O'Brien WA, Chen IS.

    J Acquir Immune Defic Syndr. 1991;4(11):1082-92.PMID: 1684385 [PubMed - indexed for MEDLINE]Related articles

    49.

    HIV-1 tropism for mononuclear phagocytes can be determined by regions of gp120 outside the CD4-binding domain.

    O'Brien WA, Koyanagi Y, Namazie A, Zhao JQ, Diagne A, Idler K, Zack JA, Chen IS.

    Nature. 1990 Nov 1;348(6296):69-73.PMID: 2172833 [PubMed - indexed for MEDLINE]Related articles

    50.

    Molecular pathogenesis of HIV-1.

    O'Brien WA, Zack JA, Chen IS.

    AIDS. 1990;4 Suppl 1:S41-8. Review. No abstract available. PMID: 2152585 [PubMed - indexed for MEDLINE]Related articles

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