PubMed

Leptin is induced in the ischemic cerebral cortex and exerts neuroprotection through NF-kappaB/c-Rel-dependent transcription.

Valerio A, Dossena M, Bertolotti P, Boroni F, Sarnico I, Faraco G, Chiarugi A, Frontini A, Giordano A, Liou HC, De Simoni MG, Spano P, Carruba MO, Pizzi M, Nisoli E.

Stroke. 2009 Feb;40(2):610-7. Epub 2008 Nov 20.PMID: 19023096 [PubMed - indexed for MEDLINE]Related articles

Morphometric changes induced by amino acid supplementation in skeletal and cardiac muscles of old mice.

Corsetti G, Pasini E, D'Antona G, Nisoli E, Flati V, Assanelli D, Dioguardi FS, Bianchi R.

Am J Cardiol. 2008 Jun 2;101(11A):26E-34E.PMID: 18514623 [PubMed - indexed for MEDLINE]Related articles

Amino acids and mitochondrial biogenesis.

Nisoli E, Cozzi V, Carruba MO.

Am J Cardiol. 2008 Jun 2;101(11A):22E-25E. Review.PMID: 18514622 [PubMed - indexed for MEDLINE]Related articles

Leptin-dependent STAT3 phosphorylation in postnatal mouse hypothalamus.

Frontini A, Bertolotti P, Tonello C, Valerio A, Nisoli E, Cinti S, Giordano A.

Brain Res. 2008 Jun 18;1215:105-15. Epub 2008 Apr 10.PMID: 18485333 [PubMed - indexed for MEDLINE]Related articles

Cannabinoid type 1 receptor blockade promotes mitochondrial biogenesis through endothelial nitric oxide synthase expression in white adipocytes.

Tedesco L, Valerio A, Cervino C, Cardile A, Pagano C, Vettor R, Pasquali R, Carruba MO, Marsicano G, Lutz B, Pagotto U, Nisoli E.

Diabetes. 2008 Aug;57(8):2028-36. Epub 2008 May 13.PMID: 18477809 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum leptin levels are higher in females affected by frontotemporal lobar degeneration than Alzheimer's disease.

Alberici A, Bocchio L, Geroldi C, Zanardini R, Bonomini C, Bugari G, Iacobello C, Caimi L, Gennarelli M, Zanetti O, Valerio A, Nisoli E, Borroni B, Padovani A.

J Neurol Neurosurg Psychiatry. 2008 Jun;79(6):712-5. Epub 2008 Feb 1.PMID: 18245138 [PubMed - indexed for MEDLINE]Related articles

Really different knockout strains in movement?

Nisoli E.

J Physiol. 2008 Feb 1;586(3):913; author reply 915-6. Epub 2007 Dec 20. No abstract available. PMID: 18096594 [PubMed - indexed for MEDLINE]Related articlesFree article

D2 dopamine receptor (DRD2) gene Taq1A polymorphism and the eating-related psychological traits in eating disorders (anorexia nervosa and bulimia) and obesity.

Nisoli E, Brunani A, Borgomainerio E, Tonello C, Dioni L, Briscini L, Redaelli G, Molinari E, Cavagnini F, Carruba MO.

Eat Weight Disord. 2007 Jun;12(2):91-6.PMID: 17615493 [PubMed - indexed for MEDLINE]Related articles

Defective mitochondrial biogenesis: a hallmark of the high cardiovascular risk in the metabolic syndrome?

Nisoli E, Clementi E, Carruba MO, Moncada S.

Circ Res. 2007 Mar 30;100(6):795-806. Review.PMID: 17395885 [PubMed - indexed for MEDLINE]Related articlesFree article

TNF-alpha downregulates eNOS expression and mitochondrial biogenesis in fat and muscle of obese rodents.

Valerio A, Cardile A, Cozzi V, Bracale R, Tedesco L, Pisconti A, Palomba L, Cantoni O, Clementi E, Moncada S, Carruba MO, Nisoli E.

J Clin Invest. 2006 Oct;116(10):2791-8. Epub 2006 Sep 14.PMID: 16981010 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitric oxide and mitochondrial biogenesis.

Nisoli E, Carruba MO.

J Cell Sci. 2006 Jul 15;119(Pt 14):2855-62.PMID: 16825426 [PubMed - indexed for MEDLINE]Related articlesFree article

White adipocytes are less prone to apoptotic stimuli than brown adipocytes in rodent.

Nisoli E, Cardile A, Bulbarelli A, Tedesco L, Bracale R, Cozzi V, Morroni M, Cinti S, Valerio A, Carruba MO.

Cell Death Differ. 2006 Dec;13(12):2154-6. Epub 2006 May 12. No abstract available. PMID: 16691210 [PubMed - indexed for MEDLINE]Related articlesFree article

A critical reflection on the definition of metabolic syndrome.

Federspil G, Nisoli E, Vettor R.

Pharmacol Res. 2006 Jun;53(6):449-56. Epub 2006 Mar 27. Review.PMID: 16632375 [PubMed - indexed for MEDLINE]Related articles

The hydrolipidic ratio in age-related maturation of adipose tissues.

Cavallini I, Marino MA, Tonello C, Marzola P, Nicolato E, Fabene PF, Calderan L, Bernardi P, Asperio RM, Nisoli E, Sbarbati A.

Biomed Pharmacother. 2006 Apr;60(3):139-43. Epub 2006 Feb 28.PMID: 16554142 [PubMed - indexed for MEDLINE]Related articles

Leptin increases axonal growth cone size in developing mouse cortical neurons by convergent signals inactivating glycogen synthase kinase-3beta.

Valerio A, Ghisi V, Dossena M, Tonello C, Giordano A, Frontini A, Ferrario M, Pizzi M, Spano P, Carruba MO, Nisoli E.

J Biol Chem. 2006 May 5;281(18):12950-8. Epub 2006 Mar 7.PMID: 16522636 [PubMed - indexed for MEDLINE]Related articlesFree article

Tumor necrosis factor-alpha induces apoptosis in rat brown adipocytes.

Nisoli E, Briscini L, Tonello C, De Giuli-Morghen C, Carruba MO.

Cell Death Differ. 1997 Dec;4(8):771-8.PMID: 16465289 [PubMed]Related articlesFree article

Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS.

Nisoli E, Tonello C, Cardile A, Cozzi V, Bracale R, Tedesco L, Falcone S, Valerio A, Cantoni O, Clementi E, Moncada S, Carruba MO.

Science. 2005 Oct 14;310(5746):314-7.PMID: 16224023 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitric oxide and mitochondrial biogenesis: a key to long-term regulation of cellular metabolism.

Clementi E, Nisoli E.

Comp Biochem Physiol A Mol Integr Physiol. 2005 Oct;142(2):102-10. Epub 2005 Aug 8. Review.PMID: 16091305 [PubMed - indexed for MEDLINE]Related articles

Regional-dependent increase of sympathetic innervation in rat white adipose tissue during prolonged fasting.

Giordano A, Frontini A, Murano I, Tonello C, Marino MA, Carruba MO, Nisoli E, Cinti S.

J Histochem Cytochem. 2005 Jun;53(6):679-87.PMID: 15928317 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of insulin and free fatty acids in the regulation of ob gene expression and plasma leptin in normal rats.

Pagano C, Dorigo A, Nisoli E, Tonello C, Calcagno A, Tami V, Granzotto M, Carruba MO, Federspil G, Vettor R.

Obes Res. 2004 Dec;12(12):2062-9.PMID: 15687408 [PubMed - indexed for MEDLINE]Related articles

Reversible transdifferentiation of secretory epithelial cells into adipocytes in the mammary gland.

Morroni M, Giordano A, Zingaretti MC, Boiani R, De Matteis R, Kahn BB, Nisoli E, Tonello C, Pisoschi C, Luchetti MM, Marelli M, Cinti S.

Proc Natl Acad Sci U S A. 2004 Nov 30;101(48):16801-6. Epub 2004 Nov 19.PMID: 15556998 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitochondrial biogenesis by NO yields functionally active mitochondria in mammals.

Nisoli E, Falcone S, Tonello C, Cozzi V, Palomba L, Fiorani M, Pisconti A, Brunelli S, Cardile A, Francolini M, Cantoni O, Carruba MO, Moncada S, Clementi E.

Proc Natl Acad Sci U S A. 2004 Nov 23;101(47):16507-12. Epub 2004 Nov 15. Erratum in: Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5635. PMID: 15545607 [PubMed - indexed for MEDLINE]Related articlesFree article

Emerging aspects of pharmacotherapy for obesity and metabolic syndrome.

Nisoli E, Carruba MO.

Pharmacol Res. 2004 Nov;50(5):453-69. Review.PMID: 15458765 [PubMed - indexed for MEDLINE]Related articles

The bioequivalence and therapeutic efficacy.

Gervasoni M, Pirola R, Bareggi SR, Tonello C, Nisoli E, Vialba L.

Clin Ther. 2004 May;26(5):801-2. No abstract available. PMID: 15220025 [PubMed - indexed for MEDLINE]Related articles

Can endogenous gaseous messengers control mitochondrial biogenesis in mammalian cells?

Nisoli E, Clementi E, Tonello C, Moncada S, Carruba MO.

Prostaglandins Other Lipid Mediat. 2004 Jan;73(1-2):9-27. Review.PMID: 15165028 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial biogenesis as a cellular signaling framework.

Nisoli E, Clementi E, Moncada S, Carruba MO.

Biochem Pharmacol. 2004 Jan 1;67(1):1-15. Review. Erratum in: Biochem Pharmacol. 2004 Feb 15;67(4):803. PMID: 14667924 [PubMed - indexed for MEDLINE]Related articles

A benefit-risk assessment of sibutramine in the management of obesity.

Nisoli E, Carruba MO.

Drug Saf. 2003;26(14):1027-48. Review.PMID: 14583064 [PubMed - indexed for MEDLINE]Related articles

The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis.

Cota D, Marsicano G, Tschöp M, Grübler Y, Flachskamm C, Schubert M, Auer D, Yassouridis A, Thöne-Reineke C, Ortmann S, Tomassoni F, Cervino C, Nisoli E, Linthorst AC, Pasquali R, Lutz B, Stalla GK, Pagotto U.

J Clin Invest. 2003 Aug;112(3):423-31.PMID: 12897210 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide.

Nisoli E, Clementi E, Paolucci C, Cozzi V, Tonello C, Sciorati C, Bracale R, Valerio A, Francolini M, Moncada S, Carruba MO.

Science. 2003 Feb 7;299(5608):896-9.PMID: 12574632 [PubMed - indexed for MEDLINE]Related articlesFree article

New pharmacological tools for obesity.

Nisoli E, Carruba MO.

J Endocrinol Invest. 2002 Nov;25(10):905-14. Review.PMID: 12508954 [PubMed - indexed for MEDLINE]Related articles

Multiple symmetric lipomatosis may be the consequence of defective noradrenergic modulation of proliferation and differentiation of brown fat cells.

Nisoli E, Regianini L, Briscini L, Bulbarelli A, Busetto L, Coin A, Enzi G, Carruba MO.

J Pathol. 2002 Nov;198(3):378-87.PMID: 12375271 [PubMed - indexed for MEDLINE]Related articles

An assessment of the safety and efficacy of sibutramine, an anti-obesity drug with a novel mechanism of action.

Nisoli E, Carruba MO.

Obes Rev. 2000 Oct;1(2):127-39. Review.PMID: 12119986 [PubMed - indexed for MEDLINE]Related articles

Changes in FAT/CD36, UCP2, UCP3 and GLUT4 gene expression during lipid infusion in rat skeletal and heart muscle.

Vettor R, Fabris R, Serra R, Lombardi AM, Tonello C, Granzotto M, Marzolo MO, Carruba MO, Ricquier D, Federspil G, Nisoli E.

Int J Obes Relat Metab Disord. 2002 Jun;26(6):838-47.PMID: 12037655 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for a functional nitric oxide synthase system in brown adipocyte nucleus.

Giordano A, Tonello C, Bulbarelli A, Cozzi V, Cinti S, Carruba MO, Nisoli E.

FEBS Lett. 2002 Mar 13;514(2-3):135-40.PMID: 11943139 [PubMed - indexed for MEDLINE]Related articles

Protective effects of noradrenaline against tumor necrosis factor-alpha-induced apoptosis in cultured rat brown adipocytes: role of nitric oxide-induced heat shock protein 70 expression.

Nisoli E, Regianini L, Bulbarelli A, Briscini L, Breacale R, Carruba MO.

Int J Obes Relat Metab Disord. 2001 Oct;25(10):1421-30.PMID: 11673761 [PubMed - indexed for MEDLINE]Related articlesFree article

Preferential channeling of energy fuels toward fat rather than muscle during high free fatty acid availability in rats.

Fabris R, Nisoli E, Lombardi AM, Tonello C, Serra R, Granzotto M, Cusin I, Rohner-Jeanrenaud F, Federspil G, Carruba MO, Vettor R.

Diabetes. 2001 Mar;50(3):601-8.PMID: 11246880 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficacy and tolerability of moclobemide in bulimia nervosa: a placebo-controlled trial.

Carruba MO, Cuzzolaro M, Riva L, Bosello O, Liberti S, Castra R, Dalle Grave R, Santonastaso P, Garosi V, Nisoli E.

Int Clin Psychopharmacol. 2001 Jan;16(1):27-32.PMID: 11195257 [PubMed - indexed for MEDLINE]Related articles

Expression and distribution of heme oxygenase-1 and -2 in rat brown adipose tissue: the modulatory role of the noradrenergic system.

Giordano A, Nisoli E, Tonello C, Cancello R, Carruba MO, Cinti S.

FEBS Lett. 2000 Dec 29;487(2):171-5.PMID: 11150503 [PubMed - indexed for MEDLINE]Related articles

Selective stimulation of somatostatin receptor subtypes: differential effects on Ras/MAP kinase pathway and cell proliferation in human neuroblastoma cells.

Cattaneo MG, Taylor JE, Culler MD, Nisoli E, Vicentini LM.

FEBS Lett. 2000 Sep 22;481(3):271-6.PMID: 11007977 [PubMed - indexed for MEDLINE]Related articles

Tumor necrosis factor alpha mediates apoptosis of brown adipocytes and defective brown adipocyte function in obesity.

Nisoli E, Briscini L, Giordano A, Tonello C, Wiesbrock SM, Uysal KT, Cinti S, Carruba MO, Hotamisligil GS.

Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):8033-8.PMID: 10884431 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of fatty acid translocase/CD36, peroxisome proliferator-activated receptor-gamma2, leptin, uncoupling proteins 2 and 3, and tumor necrosis factor-alpha gene expression in human subcutaneous fat by lipid infusion.

Nisoli E, Carruba MO, Tonello C, Macor C, Federspil G, Vettor R.

Diabetes. 2000 Mar;49(3):319-24.PMID: 10868951 [PubMed - indexed for MEDLINE]Related articlesFree article

Nutrient channelling-regulated peroxisome proliferator-activated receptor-gamma-2 (PPARgamma-2) and leptin gene expression in human subcutaneous fat.

Nisoli E, Vettor R, Tonello C, Macor C, Federspil G, Carruba MO.

Diabetologia. 1999 Apr;42(4):495-7. No abstract available. PMID: 10230656 [PubMed - indexed for MEDLINE]Related articles

Role of sympathetic activity in controlling the expression of vascular endothelial growth factor in brown fat cells of lean and genetically obese rats.

Tonello C, Giordano A, Cozzi V, Cinti S, Stock MJ, Carruba MO, Nisoli E.

FEBS Lett. 1999 Jan 15;442(2-3):167-72.PMID: 9928995 [PubMed - indexed for MEDLINE]Related articles

Effects of nitric oxide on proliferation and differentiation of rat brown adipocytes in primary cultures.

Nisoli E, Clementi E, Tonello C, Sciorati C, Briscini L, Carruba MO.

Br J Pharmacol. 1998 Oct;125(4):888-94.PMID: 9831929 [PubMed - indexed for MEDLINE]Related articlesFree article

Advances in pharmacotherapy for obesity.

Carruba M, Tomello C, Briscini L, Nisoli E.

Int J Obes Relat Metab Disord. 1998 Aug;22 Suppl 1:S13-6; discussion S17. Review.PMID: 9758239 [PubMed - indexed for MEDLINE]Related articles

SR59230A blocks beta3-adrenoceptor-linked modulation of upcoupling protein-1 and leptin in rat brown adipocytes.

Tonello C, Dioni L, Briscini L, Nisoli E, Carruba MO.

Eur J Pharmacol. 1998 Jul 3;352(1):125-9.PMID: 9718277 [PubMed - indexed for MEDLINE]Related articles

Bcl-2 and Bax are involved in the sympathetic protection of brown adipocytes from obesity-linked apoptosis.

Briscini L, Tonello C, Dioni L, Carruba MO, Nisoli E.

FEBS Lett. 1998 Jul 10;431(1):80-4.PMID: 9684870 [PubMed - indexed for MEDLINE]Related articles

Hypocretins or hyporexins?

Nisoli E, Carruba MO, Valerio A, Borsani G.

Nat Med. 1998 Jun;4(6):645. No abstract available. PMID: 9623954 [PubMed - indexed for MEDLINE]Related articles

Nerve growth factor, beta3-adrenoceptor and uncoupling protein 1 expression in rat brown fat during postnatal development.

Nisoli E, Tonello C, Carruba MO.

Neurosci Lett. 1998 Apr 17;246(1):5-8.PMID: 9622194 [PubMed - indexed for MEDLINE]Related articles

In memory of dexfenfluramine: R.I.P.

Carruba MO, Nisoli E.

Int J Obes Relat Metab Disord. 1997 Dec;21(12):1193. No abstract available. PMID: 9426390 [PubMed - indexed for MEDLINE]Related articles