PubMed

Effect of dietary oils on host resistance to fungal infection in psychologically stressed mice.

Oarada M, Igarashi M, Tsuzuki T, Kurita N, Gonoi T, Nikawa T, Hirasaka K, Miyazawa T, Nakagawa K, Kamei K.

Biosci Biotechnol Biochem. 2009 Sep;73(9):1994-8. Epub 2009 Sep 7.PMID: 19734677 [PubMed - in process]Related articlesFree article

[Development of ubiquitin ligase inhibitor as a drug against unloading-mediated muscle atrophy]

Nikawa T.

Seikagaku. 2009 Jul;81(7):614-8. Review. Japanese. No abstract available. PMID: 19697867 [PubMed - indexed for MEDLINE]Related articles

Ubiquitin ligase Cbl-b is a negative regulator for insulin-like growth factor 1 signaling during muscle atrophy caused by unloading.

Nakao R, Hirasaka K, Goto J, Ishidoh K, Yamada C, Ohno A, Okumura Y, Nonaka I, Yasutomo K, Baldwin KM, Kominami E, Higashibata A, Nagano K, Tanaka K, Yasui N, Mills EM, Takeda S, Nikawa T.

Mol Cell Biol. 2009 Sep;29(17):4798-811. Epub 2009 Jun 22.PMID: 19546233 [PubMed - indexed for MEDLINE]Related articles

Beneficial effects of a low-protein diet on host resistance to Paracoccidioides brasiliensis in mice.

Oarada M, Kamei K, Gonoi T, Tsuzuki T, Toyotome T, Hirasaka K, Nikawa T, Sato A, Kurita N.

Nutrition. 2009 Sep;25(9):954-63. Epub 2009 Apr 28.PMID: 19403266 [PubMed - indexed for MEDLINE]Related articles

Awa (Tokushima) lactate-fermented tea as well as green tea enhance the effect of diet restriction on obesity in rats.

Sogawa M, Seura T, Kohno S, Hirasaka K, Yamaguchi Y, Takagaki R, Harada A, Okumura Y, Yamamoto S, Kishi K, Nikawa T.

J Med Invest. 2009 Feb;56(1-2):42-8.PMID: 19262013 [PubMed - indexed for MEDLINE]Related articlesFree article

Polyphenols prevent clinorotation-induced expression of atrogenes in mouse C2C12 skeletal myotubes.

Hemdan DI, Hirasaka K, Nakao R, Kohno S, Kagawa S, Abe T, Harada-Sukeno A, Okumura Y, Nakaya Y, Terao J, Nikawa T.

J Med Invest. 2009 Feb;56(1-2):26-32.PMID: 19262011 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose infusion suppresses surgery-induced muscle protein breakdown by inhibiting ubiquitin-proteasome pathway in rats.

Mikura M, Yamaoka I, Doi M, Kawano Y, Nakayama M, Nakao R, Hirasaka K, Okumura Y, Nikawa T.

Anesthesiology. 2009 Jan;110(1):81-8.PMID: 19104174 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of dimethyl sulphoxide and dexamethasone on mRNA expression of myogenesis- and muscle proteolytic system-related genes in mouse myoblastic C2C12 cells.

Nishimura M, Mikura M, Hirasaka K, Okumura Y, Nikawa T, Kawano Y, Nakayama M, Ikeda M.

J Biochem. 2008 Dec;144(6):717-24. Epub 2008 Oct 3.PMID: 18835828 [PubMed - indexed for MEDLINE]Related articles

Peroxidized cholesterol-induced matrix metalloproteinase-9 activation and its suppression by dietary beta-carotene in photoaging of hairless mouse skin.

Minami Y, Kawabata K, Kubo Y, Arase S, Hirasaka K, Nikawa T, Bando N, Kawai Y, Terao J.

J Nutr Biochem. 2009 May;20(5):389-98. Epub 2008 Jul 24.PMID: 18656335 [PubMed - indexed for MEDLINE]Related articles

Cathepsin C propeptide interacts with intestinal alkaline phosphatase and heat shock cognate protein 70 in human Caco-2 cells.

Hirasaka K, Tokuoka K, Nakao R, Yamada C, Oarada M, Imagawa T, Ishidoh K, Okumura Y, Kishi K, Nikawa T.

J Physiol Sci. 2008 Apr;58(2):105-11. Epub 2008 Mar 1.PMID: 18307834 [PubMed - indexed for MEDLINE]Related articles

Subcutaneous injection, from birth, of epigallocatechin-3-gallate, a component of green tea, limits the onset of muscular dystrophy in mdx mice: a quantitative histological, immunohistochemical and electrophysiological study.

Nakae Y, Hirasaka K, Goto J, Nikawa T, Shono M, Yoshida M, Stoward PJ.

Histochem Cell Biol. 2008 Apr;129(4):489-501. Epub 2008 Feb 9.PMID: 18264714 [PubMed - indexed for MEDLINE]Related articles

Effects of dimethyl sulfoxide and dexamethasone on mRNA expression of housekeeping genes in cultures of C2C12 myotubes.

Nishimura M, Nikawa T, Kawano Y, Nakayama M, Ikeda M.

Biochem Biophys Res Commun. 2008 Mar 14;367(3):603-8. Epub 2008 Jan 10.PMID: 18191039 [PubMed - indexed for MEDLINE]Related articles

Effects of dietary fish oil on lipid peroxidation and serum triacylglycerol levels in psychologically stressed mice.

Oarada M, Tsuzuki T, Gonoi T, Igarashi M, Kamei K, Nikawa T, Hirasaka K, Ogawa T, Miyazawa T, Nakagawa K, Kurita N.

Nutrition. 2008 Jan;24(1):67-75.PMID: 18070659 [PubMed - indexed for MEDLINE]Related articles

Osteoactivin fragments produced by ectodomain shedding induce MMP-3 expression via ERK pathway in mouse NIH-3T3 fibroblasts.

Furochi H, Tamura S, Mameoka M, Yamada C, Ogawa T, Hirasaka K, Okumura Y, Imagawa T, Oguri S, Ishidoh K, Kishi K, Higashiyama S, Nikawa T.

FEBS Lett. 2007 Dec 22;581(30):5743-50. Epub 2007 Nov 26.PMID: 18036345 [PubMed - indexed for MEDLINE]Related articles

Distinct effects of anterior pyriform cortex and the lateral hypothalamus lesions on protein intake in rats.

Nakao R, Ozaki E, Hasegawa M, Kondo A, Uezu K, Hirasaka K, Nikawa T, Kishi K.

J Med Invest. 2007 Aug;54(3-4):255-60.PMID: 17878674 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of osteoactivin protects skeletal muscle from severe degeneration caused by long-term denervation in mice.

Furochi H, Tamura S, Takeshima K, Hirasaka K, Nakao R, Kishi K, Nikawa T.

J Med Invest. 2007 Aug;54(3-4):248-54.PMID: 17878673 [PubMed - indexed for MEDLINE]Related articlesFree article

Deficiency of Cbl-b gene enhances infiltration and activation of macrophages in adipose tissue and causes peripheral insulin resistance in mice.

Hirasaka K, Kohno S, Goto J, Furochi H, Mawatari K, Harada N, Hosaka T, Nakaya Y, Ishidoh K, Obata T, Ebina Y, Gu H, Takeda S, Kishi K, Nikawa T.

Diabetes. 2007 Oct;56(10):2511-22. Epub 2007 Jun 29.PMID: 17601987 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of single administration of Rokumi-gan (TJ-87) on serum amino acid concentration of 6 healthy Japanese male volunteers.

Takahashi H, Nakao R, Hirasaka K, Kishi K, Nikawa T.

J Med Invest. 2007 Feb;54(1-2):91-8.PMID: 17380019 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of dietary oils on lymphocyte immunological activity in psychologically stressed mice.

Oarada M, Gonoi T, Tsuzuki T, Igarashi M, Hirasaka K, Nikawa T, Onishi Y, Toyotome T, Kamei K, Miyazawa T, Nakagawa K, Kashima M, Kurita N.

Biosci Biotechnol Biochem. 2007 Jan;71(1):174-82. Epub 2007 Jan 7.PMID: 17213666 [PubMed - indexed for MEDLINE]Related articlesFree article

Distinct expression of mast cell tryptase and protease activated receptor-2 in synovia of rheumatoid arthritis and osteoarthritis.

Nakano S, Mishiro T, Takahara S, Yokoi H, Hamada D, Yukata K, Takata Y, Goto T, Egawa H, Yasuoka S, Furouchi H, Hirasaka K, Nikawa T, Yasui N.

Clin Rheumatol. 2007 Aug;26(8):1284-92. Epub 2007 Jan 5.PMID: 17205215 [PubMed - indexed for MEDLINE]Related articles

Restraint stress alters the duodenal expression of genes important for lipid metabolism in rat.

Sato T, Yamamoto H, Sawada N, Nashiki K, Tsuji M, Muto K, Kume H, Sasaki H, Arai H, Nikawa T, Taketani Y, Takeda E.

Toxicology. 2006 Oct 29;227(3):248-61. Epub 2006 Aug 14.PMID: 16962226 [PubMed - indexed for MEDLINE]Related articles

Soy protein diet prevents hypermethioninemia caused by portacaval shunt in rats.

Shimooka R, Yasuhiro K, Chiba N, Tanaka J, Rokutan K, Furochi H, Hirasaka K, Nikawa T, Kishi K.

J Med Invest. 2006 Aug;53(3-4):255-63.PMID: 16953062 [PubMed - indexed for MEDLINE]Related articlesFree article

Ubiquitin ligase gene expression in healthy volunteers with 20-day bedrest.

Ogawa T, Furochi H, Mameoka M, Hirasaka K, Onishi Y, Suzue N, Oarada M, Akamatsu M, Akima H, Fukunaga T, Kishi K, Yasui N, Ishidoh K, Fukuoka H, Nikawa T.

Muscle Nerve. 2006 Oct;34(4):463-9.PMID: 16868939 [PubMed - indexed for MEDLINE]Related articles

Immobilization decreases duodenal calcium absorption through a 1,25-dihydroxyvitamin D-dependent pathway.

Sato T, Yamamoto H, Sawada N, Nashiki K, Tsuji M, Nikawa T, Arai H, Morita K, Taketani Y, Takeda E.

J Bone Miner Metab. 2006;24(4):291-9.PMID: 16816923 [PubMed - indexed for MEDLINE]Related articles

Ubiquitin ligase Cbl-b downregulates bone formation through suppression of IGF-I signaling in osteoblasts during denervation.

Suzue N, Nikawa T, Onishi Y, Yamada C, Hirasaka K, Ogawa T, Furochi H, Kosaka H, Ishidoh K, Gu H, Takeda S, Ishimaru N, Hayashi Y, Yamamoto H, Kishi K, Yasui N.

J Bone Miner Res. 2006 May;21(5):722-34.PMID: 16734387 [PubMed - indexed for MEDLINE]Related articles

Identification of mono-ubiquitinated LDH-A in skeletal muscle cells exposed to oxidative stress.

Onishi Y, Hirasaka K, Ishihara I, Oarada M, Goto J, Ogawa T, Suzue N, Nakano S, Furochi H, Ishidoh K, Kishi K, Nikawa T.

Biochem Biophys Res Commun. 2005 Oct 28;336(3):799-806.PMID: 16154111 [PubMed - indexed for MEDLINE]Related articles

Short-term hypergravity does not affect protein-ubiquitination and proliferation in rat L6 myoblastic cells.

Hirasaka K, Nikawa T, Asanoma Y, Furochi H, Onishi Y, Ogawa T, Suzue N, Oarada M, Shimazu T, Kishi K.

Biol Sci Space. 2005 Mar;19(1):3-7.PMID: 16118477 [PubMed - indexed for MEDLINE]Related articlesFree article

Osteoactivin upregulates expression of MMP-3 and MMP-9 in fibroblasts infiltrated into denervated skeletal muscle in mice.

Ogawa T, Nikawa T, Furochi H, Kosyoji M, Hirasaka K, Suzue N, Sairyo K, Nakano S, Yamaoka T, Itakura M, Kishi K, Yasui N.

Am J Physiol Cell Physiol. 2005 Sep;289(3):C697-707.PMID: 16100390 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinorotation prevents differentiation of rat myoblastic L6 cells in association with reduced NF-kappa B signaling.

Hirasaka K, Nikawa T, Yuge L, Ishihara I, Higashibata A, Ishioka N, Okubo A, Miyashita T, Suzue N, Ogawa T, Oarada M, Kishi K.

Biochim Biophys Acta. 2005 Mar 22;1743(1-2):130-40.PMID: 15777848 [PubMed - indexed for MEDLINE]Related articles

Relationship between cathepsin B and thrombin in rheumatoid arthritis.

Mishiro T, Nakano S, Takahara S, Miki M, Nakamura Y, Yasuoka S, Nikawa T, Yasui N.

J Rheumatol. 2004 Jul;31(7):1265-73.PMID: 15229942 [PubMed - indexed for MEDLINE]Related articles

Skeletal muscle gene expression in space-flown rats.

Nikawa T, Ishidoh K, Hirasaka K, Ishihara I, Ikemoto M, Kano M, Kominami E, Nonaka I, Ogawa T, Adams GR, Baldwin KM, Yasui N, Kishi K, Takeda S.

FASEB J. 2004 Mar;18(3):522-4. Epub 2004 Jan 8.PMID: 14715702 [PubMed - indexed for MEDLINE]Related articlesFree article

Physical stress by magnetic force accelerates differentiation of human osteoblasts.

Yuge L, Okubo A, Miyashita T, Kumagai T, Nikawa T, Takeda S, Kanno M, Urabe Y, Sugiyama M, Kataoka K.

Biochem Biophys Res Commun. 2003 Nov 7;311(1):32-8.PMID: 14575691 [PubMed - indexed for MEDLINE]Related articles

Dietary supplementation with docosahexaenoic acid, but not with eicosapentaenoic acid, reduces host resistance to fungal infection in mice.

Oarada M, Tsuduki T, Suzuki T, Miyazawa T, Nikawa T, Hong-quan G, Kurita N.

Biochim Biophys Acta. 2003 Aug 22;1622(3):151-60.PMID: 12928111 [PubMed - indexed for MEDLINE]Related articles

Isolation and characterization of a novel gene sfig in rat skeletal muscle up-regulated by spaceflight (STS-90).

Kano M, Kitano T, Ikemoto M, Hirasaka K, Asanoma Y, Ogawa T, Takeda S, Nonaka I, Adams GR, Baldwin KM, Oarada M, Kishi K, Nikawa T.

J Med Invest. 2003 Feb;50(1-2):39-47.PMID: 12630567 [PubMed - indexed for MEDLINE]Related articles

A relative high dose of vitamin E does not attenuate unweighting-induced oxidative stress and ubiquitination in rat skeletal muscle.

Ikemoto M, Okamura Y, Kano M, Hirasaka K, Tanaka R, Yamamoto T, Sasa T, Ogawa T, Sairyo K, Kishi K, Nikawa T.

J Physiol Anthropol Appl Human Sci. 2002 Sep;21(5):257-63.PMID: 12491823 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of timing of food deprivation on host resistance to fungal infection in mice.

Oarada M, Nikawa T, Kurita N.

Br J Nutr. 2002 Aug;88(2):151-8.PMID: 12144718 [PubMed - indexed for MEDLINE]Related articles

Effects of a soy protein diet on exercise-induced muscle protein catabolism in rats.

Nikawa T, Ikemoto M, Sakai T, Kano M, Kitano T, Kawahara T, Teshima S, Rokutan K, Kishi K.

Nutrition. 2002 Jun;18(6):490-5.PMID: 12044822 [PubMed - indexed for MEDLINE]Related articles

Cysteine supplementation prevents unweighting-induced ubiquitination in association with redox regulation in rat skeletal muscle.

Ikemoto M, Nikawa T, Kano M, Hirasaka K, Kitano T, Watanabe C, Tanaka R, Yamamoto T, Kamada M, Kishi K.

Biol Chem. 2002 Mar-Apr;383(3-4):715-21.PMID: 12033461 [PubMed - indexed for MEDLINE]Related articles

[Gene expression in skeletal muscle of spaceflight rat]

Nikawa T, Ikemoto M, Kano M, Hirasaka K, Takeda SI, Baldwin KM, Nonaka I, Ishido K, Kominami H, Rokutan K, Kishi K.

Biol Sci Space. 2001 Oct;15(3):312-3. Japanese. No abstract available. PMID: 11997658 [PubMed - indexed for MEDLINE]Related articles

A cysteine protease inhibitor prevents suspension-induced declines in bone weight and strength in rats.

Nikawa T, Ikemoto M, Watanabe C, Kitano T, Kano M, Yoshimoto M, Towatari T, Katunuma N, Shizuka F, Kishi K.

J Physiol Anthropol Appl Human Sci. 2002 Jan;21(1):51-7.PMID: 11938609 [PubMed - indexed for MEDLINE]Related articlesFree article

Toll-like receptor 4 regulates gastric pit cell responses to Helicobacter pylori infection.

Kawahara T, Kuwano Y, Teshima-Kondo S, Kawai T, Nikawa T, Kishi K, Rokutan K.

J Med Invest. 2001 Aug;48(3-4):190-7.PMID: 11694959 [PubMed - indexed for MEDLINE]Related articles

Helicobacter pylori lipopolysaccharide from type I, but not type II strains, stimulates apoptosis of cultured gastric mucosal cells.

Kawahara T, Kuwano Y, Teshima-Kondo S, Sugiyama T, Kawai T, Nikawa T, Kishi K, Rokutan K.

J Med Invest. 2001 Aug;48(3-4):167-74.PMID: 11694956 [PubMed - indexed for MEDLINE]Related articles

Impaired vitamin A-mediated mucosal IgA response in IL-5 receptor-knockout mice.

Nikawa T, Ikemoto M, Kano M, Tokuoka K, Hirasaka K, Uehara S, Takatsu K, Rokutan K, Kishi K.

Biochem Biophys Res Commun. 2001 Jul 13;285(2):546-9.PMID: 11444878 [PubMed - indexed for MEDLINE]Related articles

Space shuttle flight (STS-90) enhances degradation of rat myosin heavy chain in association with activation of ubiquitin-proteasome pathway.

Ikemoto M, Nikawa T, Takeda S, Watanabe C, Kitano T, Baldwin KM, Izumi R, Nonaka I, Towatari T, Teshima S, Rokutan K, Kishi K.

FASEB J. 2001 May;15(7):1279-81. No abstract available. PMID: 11344113 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin-1beta enhances retinoic acid-mediated expression of bone-type alkaline phosphatase in rat IEC-6 cells.

Nikawa T, Ikemoto M, Tokuoka K, Teshima S, Alpers DH, Masui Y, Kishi K, Rokutan K.

Am J Physiol Gastrointest Liver Physiol. 2001 Mar;280(3):G510-7.PMID: 11171635 [PubMed - indexed for MEDLINE]Related articlesFree article

Vitamin A prevents the decline in immunoglobulin A and Th2 cytokine levels in small intestinal mucosa of protein-malnourished mice.

Nikawa T, Odahara K, Koizumi H, Kido Y, Teshima S, Rokutan K, Kishi K.

J Nutr. 1999 May;129(5):934-41.PMID: 10222382 [PubMed - indexed for MEDLINE]Related articlesFree article

Macrophage colony-stimulating factor stimulates synthesis and secretion of a mouse homolog of a human IgE-dependent histamine-releasing factor by macrophages in vitro and in vivo.

Teshima S, Rokutan K, Nikawa T, Kishi K.

J Immunol. 1998 Dec 1;161(11):6356-66.PMID: 9834126 [PubMed - indexed for MEDLINE]Related articlesFree article

Vitamin A up-regulates expression of bone-type alkaline phosphatase in rat small intestinal crypt cell line and fetal rat small intestine.

Nikawa T, Rokutan K, Nanba K, Tokuoka K, Teshima S, Engle MJ, Alpers DH, Kishi K.

J Nutr. 1998 Nov;128(11):1869-77.PMID: 9808636 [PubMed - indexed for MEDLINE]Related articlesFree article

Guinea pig gastric mucosal cells produce abundant superoxide anion through an NADPH oxidase-like system.

Teshima S, Rokutan K, Nikawa T, Kishi K.

Gastroenterology. 1998 Nov;115(5):1186-96.PMID: 9797374 [PubMed - indexed for MEDLINE]Related articles

Glutathione depletion inhibits oxidant-induced activation of nuclear factor-kappa B, AP-1, and c-Jun/ATF-2 in cultured guinea-pig gastric epithelial cells.

Rokutan K, Teshima S, Miyoshi M, Kawai T, Nikawa T, Kishi K.

J Gastroenterol. 1998 Oct;33(5):646-55.PMID: 9773928 [PubMed - indexed for MEDLINE]Related articles