PubMed

Therapeutic conversion of the combination of ipratropium and albuterol to tiotropium in patients with chronic obstructive pulmonary disease.

Niewoehner DE, Lapidus R, Cote C, Sharafkhaneh A, Plautz M, Johnson P, Kesten S.

Pulm Pharmacol Ther. 2009 Dec;22(6):587-92. Epub 2009 Sep 6.PMID: 19737620 [PubMed - in process]Related articles

TORCH and UPLIFT: what has been learned from the COPD "mega-trials"?

Niewoehner DE.

COPD. 2009 Feb;6(1):1-3.PMID: 19229702 [PubMed - indexed for MEDLINE]Related articles

Exhaled nitric oxide, systemic inflammation, and the spirometric response to inhaled fluticasone propionate in severe chronic obstructive pulmonary disease: a prospective study.

Kunisaki KM, Rice KL, Janoff EN, Rector TS, Niewoehner DE.

Ther Adv Respir Dis. 2008 Apr;2(2):55-64.PMID: 19124359 [PubMed - indexed for MEDLINE]Related articles

Antibiotic prophylaxis for chronic obstructive pulmonary disease: resurrecting an old idea.

Kunisaki KM, Niewoehner DE.

Am J Respir Crit Care Med. 2008 Dec 1;178(11):1098-9. No abstract available. PMID: 19023036 [PubMed - indexed for MEDLINE]Related articles

Relation of chronic obstructive pulmonary disease exacerbations to FEV(1)--an intricate tango.

Niewoehner DE.

Respiration. 2009;77(2):229-35. Epub 2008 Oct 7. Review.PMID: 18840996 [PubMed - indexed for MEDLINE]Related articles

Oral prednisolone was not inferior to intravenous prednisolone for treatment failure in chronic obstructive pulmonary disease exacerbation.

Niewoehner DE.

Evid Based Med. 2008 Oct;13(5):145. No abstract available. PMID: 18836113 [PubMed]Related articles

Viral pathogens in acute exacerbations of chronic obstructive pulmonary disease.

Camargo CA Jr, Ginde AA, Clark S, Cartwright CP, Falsey AR, Niewoehner DE.

Intern Emerg Med. 2008 Dec;3(4):355-9. Epub 2008 Sep 30.PMID: 18825480 [PubMed - indexed for MEDLINE]Related articles

Responses to tiotropium in African-American and Caucasian patients with chronic obstructive pulmonary disease.

Rice KL, Leimer I, Kesten S, Niewoehner DE.

Transl Res. 2008 Aug;152(2):88-94. Epub 2008 Jun 23.PMID: 18674743 [PubMed - indexed for MEDLINE]Related articles

Role of tiotropium in the treatment of COPD.

Rice KL, Kunisaki KM, Niewoehner DE.

Int J Chron Obstruct Pulmon Dis. 2007;2(2):95-105. Review.PMID: 18044681 [PubMed - indexed for MEDLINE]Related articlesFree article

Premature discontinuation of patients: a potential bias in COPD clinical trials.

Kesten S, Plautz M, Piquette CA, Habib MP, Niewoehner DE.

Eur Respir J. 2007 Nov;30(5):898-906. Epub 2007 Aug 9. Erratum in: Eur Respir J. 2008 Jan;31(1):226. PMID: 17690120 [PubMed - indexed for MEDLINE]Related articlesFree article

Procalcitonin level-guided treatment reduced antibiotic use in exacerbations of COPD.

Niewoehner DE.

ACP J Club. 2007 May-Jun;146(3):57. No abstract available. PMID: 17474666 [PubMed]Related articles

Management of acute exacerbations of chronic obstructive pulmonary disease in the elderly : an appraisal of published evidence.

Kunisaki KM, Rice KL, Niewoehner DE.

Drugs Aging. 2007;24(4):303-24. Review.PMID: 17432925 [PubMed - indexed for MEDLINE]Related articles

Risk indexes for exacerbations and hospitalizations due to COPD.

Niewoehner DE, Lokhnygina Y, Rice K, Kuschner WG, Sharafkhaneh A, Sarosi GA, Krumpe P, Pieper K, Kesten S.

Chest. 2007 Jan;131(1):20-8.PMID: 17218552 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhaled corticosteroids for chronic obstructive pulmonary disease: a status report.

Niewoehner DE, Wilt TJ.

Am J Respir Crit Care Med. 2007 Jan 15;175(2):103-4. No abstract available. PMID: 17200504 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical efficacy of OM-85 BV in COPD and chronic bronchitis: a systematic review.

Sprenkle MD, Niewoehner DE, MacDonald R, Rutks I, Wilt TJ.

COPD. 2005 Mar;2(1):167-75. Review.PMID: 17136978 [PubMed - indexed for MEDLINE]Related articles

Disease management as an evolving role for respiratory therapists.

Stoller JK, Niewoehner DE, Fan VS.

Respir Care. 2006 Dec;51(12):1400-2. No abstract available. PMID: 17134519 [PubMed - indexed for MEDLINE]Related articlesFree article

The impact of severe exacerbations on quality of life and the clinical course of chronic obstructive pulmonary disease.

Niewoehner DE.

Am J Med. 2006 Oct;119(10 Suppl 1):38-45. Review.PMID: 16996898 [PubMed - indexed for MEDLINE]Related articles

Prevention of exacerbations of chronic obstructive pulmonary disease with tiotropium, a once-daily inhaled anticholinergic bronchodilator: a randomized trial.

Niewoehner DE, Rice K, Cote C, Paulson D, Cooper JA Jr, Korducki L, Cassino C, Kesten S.

Ann Intern Med. 2005 Sep 6;143(5):317-26.PMID: 16144890 [PubMed - indexed for MEDLINE]Related articlesFree article

Interventions to prevent chronic obstructive pulmonary disease exacerbations.

Niewoehner DE.

Am J Med. 2004 Dec 20;117 Suppl 12A:41S-48S. Review.PMID: 15693642 [PubMed - indexed for MEDLINE]Related articles

The Veterans Short Form 36 questionnaire is predictive of mortality and health-care utilization in a population of veterans with a self-reported diagnosis of asthma or COPD.

Sprenkle MD, Niewoehner DE, Nelson DB, Nichol KL.

Chest. 2004 Jul;126(1):81-9.PMID: 15249446 [PubMed - indexed for MEDLINE]Related articlesFree article

Review: methylxanthines are not effective for acute exacerbations of chronic obstructive pulmonary disease.

Niewoehner DE.

ACP J Club. 2004 May-Jun;140(3):60. No abstract available. PMID: 15122823 [PubMed]Related articles

The role of systemic corticosteroids in acute exacerbation of chronic obstructive pulmonary disease.

Niewoehner DE.

Am J Respir Med. 2002;1(4):243-8. Review.PMID: 14720044 [PubMed - indexed for MEDLINE]Related articles

Review: ipratropium is not more effective than beta 2-agonists for acute exacerbations of chronic obstructive pulmonary disease.

Niewoehner DE.

ACP J Club. 2003 May-Jun;138(3):73. No abstract available. PMID: 12725628 [PubMed]Related articles

Screening for lung cancer: the guidelines.

Bach PB, Niewoehner DE, Black WC; American College of Chest Physicians.

Chest. 2003 Jan;123(1 Suppl):83S-88S.PMID: 12527567 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical utility of tumor markers in the management of non-small cell lung cancer.

Niewoehner DE, Rubins JB.

Methods Mol Med. 2003;75:135-41. Review. No abstract available. PMID: 12407738 [PubMed - indexed for MEDLINE]Related articles

Montelukast improved pulmonary function and asthma-specific quality of life in aspirin-intolerant asthma.

Niewoehner DE.

ACP J Club. 2002 Jul-Aug;137(1):20. No abstract available. PMID: 12093219 [PubMed]Related articles

Role of corticosteroids in acute exacerbations of chronic obstructive pulmonary disease.

Niewoehner DE.

Curr Opin Pulm Med. 2001 Mar;7(2):75-8. Review.PMID: 11224727 [PubMed - indexed for MEDLINE]Related articles

Corticosteroids in chronic obstructive pulmonary disease. Clinical benefits and risks.

McEvoy CE, Niewoehner DE.

Clin Chest Med. 2000 Dec;21(4):739-52. Review.PMID: 11194783 [PubMed - indexed for MEDLINE]Related articles

Withdrawal of chronic systemic corticosteroids in patients with COPD: a randomized trial.

Rice KL, Rubins JB, Lebahn F, Parenti CM, Duane PG, Kuskowski M, Joseph AM, Niewoehner DE.

Am J Respir Crit Care Med. 2000 Jul;162(1):174-8.PMID: 10903238 [PubMed - indexed for MEDLINE]Related articlesFree article

Relation of FEV(1) to clinical outcomes during exacerbations of chronic obstructive pulmonary disease. Department of Veterans Affairs Cooperative Study Group.

Niewoehner DE, Collins D, Erbland ML.

Am J Respir Crit Care Med. 2000 Apr;161(4 Pt 1):1201-5.PMID: 10764312 [PubMed - indexed for MEDLINE]Related articlesFree article

Systemic corticosteroids for chronic obstructive pulmonary disease: benefits and risks.

Niewoehner DE.

Monaldi Arch Chest Dis. 1999 Oct;54(5):422-6. Review.PMID: 10741103 [PubMed - indexed for MEDLINE]Related articles

Effect of systemic glucocorticoids on exacerbations of chronic obstructive pulmonary disease. Department of Veterans Affairs Cooperative Study Group.

Niewoehner DE, Erbland ML, Deupree RH, Collins D, Gross NJ, Light RW, Anderson P, Morgan NA.

N Engl J Med. 1999 Jun 24;340(25):1941-7.PMID: 10379017 [PubMed - indexed for MEDLINE]Related articlesFree article

Steroid-induced osteoporosis. Are your asthmatic patients at risk?

Niewoehner CB, Niewoehner DE.

Postgrad Med. 1999 Mar;105(3):79-83, 87-8, 91. Review.PMID: 10086035 [PubMed - indexed for MEDLINE]Related articles

Serum carcinoembryonic antigen as an adjunct to preoperative staging of lung cancer.

Rubins JB, Dunitz J, Rubins HB, Maddaus MA, Niewoehner DE.

J Thorac Cardiovasc Surg. 1998 Sep;116(3):412-6.PMID: 9731783 [PubMed - indexed for MEDLINE]Related articles

Systemic Corticosteroids in Chronic Obstructive Pulmonary Disease Exacerbations (SCCOPE): rationale and design of an equivalence trial. Veterans Administration Cooperative Trials SCCOPE Study Group.

Erbland ML, Deupree RH, Niewoehner DE.

Control Clin Trials. 1998 Aug;19(4):404-17.PMID: 9683314 [PubMed - indexed for MEDLINE]Related articles

Do molecular markers predict survival in non-small-cell lung cancer?

Greatens TM, Niehans GA, Rubins JB, Jessurun J, Kratzke RA, Maddaus MA, Niewoehner DE.

Am J Respir Crit Care Med. 1998 Apr;157(4 Pt 1):1093-7.PMID: 9563724 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between corticosteroid use and vertebral fractures in older men with chronic obstructive pulmonary disease.

McEvoy CE, Ensrud KE, Bender E, Genant HK, Yu W, Griffith JM, Niewoehner DE.

Am J Respir Crit Care Med. 1998 Mar;157(3 Pt 1):704-9.PMID: 9517579 [PubMed - indexed for MEDLINE]Related articlesFree article

Adverse effects of corticosteroid therapy for COPD. A critical review.

McEvoy CE, Niewoehner DE.

Chest. 1997 Mar;111(3):732-43. Review.PMID: 9118715 [PubMed - indexed for MEDLINE]Related articlesFree article

Systemic corticosteroids in COPD. An unresolved clinical dilemma.

Niewoehner DE, Erbland ML.

Chest. 1996 Oct;110(4):867-9. No abstract available. PMID: 8874233 [PubMed - indexed for MEDLINE]Related articlesFree article

Rb and p16INK4a expression in resected non-small cell lung tumors.

Kratzke RA, Greatens TM, Rubins JB, Maddaus MA, Niewoehner DE, Niehans GA, Geradts J.

Cancer Res. 1996 Aug 1;56(15):3415-20.PMID: 8758904 [PubMed - indexed for MEDLINE]Related articlesFree article

Lung cancer surgery. A critical review of the evidence.

Lederle FA, Niewoehner DE.

Arch Intern Med. 1994 Nov 14;154(21):2397-400. Review.PMID: 7979834 [PubMed - indexed for MEDLINE]Related articles

Pneumolysin activates phospholipase A in pulmonary artery endothelial cells.

Rubins JB, Mitchell TJ, Andrew PW, Niewoehner DE.

Infect Immun. 1994 Sep;62(9):3829-36.PMID: 8063399 [PubMed - indexed for MEDLINE]Related articlesFree article

Toxicity of pneumolysin to pulmonary alveolar epithelial cells.

Rubins JB, Duane PG, Clawson D, Charboneau D, Young J, Niewoehner DE.

Infect Immun. 1993 Apr;61(4):1352-8.PMID: 8454338 [PubMed - indexed for MEDLINE]Related articlesFree article

Amiodarone-induced endothelial injury is associated with phospholipase C-mediated hydrolysis of membrane phospholipids.

Duane PG, Rice KL, Charboneau DE, Niewoehner DE.

J Lab Clin Med. 1992 Dec;120(6):955-63.PMID: 1453116 [PubMed - indexed for MEDLINE]Related articles

Time course of functional repair of the alveolar epithelium after hyperoxic injury.

Palazzo RM, Wangensteen OD, Niewoehner DE.

J Appl Physiol. 1992 Nov;73(5):1881-7.PMID: 1474064 [PubMed - indexed for MEDLINE]Related articles

H2O2 injury causes Ca(2+)-dependent and -independent hydrolysis of phosphatidylcholine in alveolar epithelial cells.

Rice KL, Duane PG, Archer SL, Gilboe DP, Niewoehner DE.

Am J Physiol. 1992 Oct;263(4 Pt 1):L430-8.PMID: 1415720 [PubMed - indexed for MEDLINE]Related articles

Some antiphospholipid antibodies inhibit phospholipase A2 activity.

Schorer AE, Duane PG, Woods VL, Niewoehner DE.

J Lab Clin Med. 1992 Jul;120(1):67-77.PMID: 1613330 [PubMed - indexed for MEDLINE]Related articles

What lies ahead? Future research and treatment for chronic obstructive pulmonary disease.

Niewoehner DE.

Am J Med. 1991 Oct 21;91(4A):41S-46S. Review.PMID: 1951403 [PubMed - indexed for MEDLINE]Related articles

Cadmium ion-induced alterations of phospholipid metabolism in endothelial cells.

Nelson JM, Duane PG, Rice KL, Niewoehner DE.

Am J Respir Cell Mol Biol. 1991 Oct;5(4):328-36.PMID: 1910817 [PubMed - indexed for MEDLINE]Related articles

Relationship of oxidant-mediated cytotoxicity to phospholipid metabolism in endothelial cells.

Duane PG, Rice KL, Charboneau DE, King MB, Gilboe DP, Niewoehner DE.

Am J Respir Cell Mol Biol. 1991 May;4(5):408-16.PMID: 2021479 [PubMed - indexed for MEDLINE]Related articles