PubMed

Clinical studies with oral lipid based formulations of poorly soluble compounds.

Fatouros DG, Karpf DM, Nielsen FS, Mullertz A.

Ther Clin Risk Manag. 2007 Aug;3(4):591-604.PMID: 18472981 [PubMed - in process]Related articlesFree article

In vitro-in vivo correlations of self-emulsifying drug delivery systems combining the dynamic lipolysis model and neuro-fuzzy networks.

Fatouros DG, Nielsen FS, Douroumis D, Hadjileontiadis LJ, Mullertz A.

Eur J Pharm Biopharm. 2008 Aug;69(3):887-98. Epub 2008 Feb 1.PMID: 18367386 [PubMed - indexed for MEDLINE]Related articles

Bioavailability of probucol from lipid and surfactant based formulations in minipigs: influence of droplet size and dietary state.

Nielsen FS, Petersen KB, Müllertz A.

Eur J Pharm Biopharm. 2008 Jun;69(2):553-62. Epub 2008 Jan 3.PMID: 18294829 [PubMed - indexed for MEDLINE]Related articles

Using biorelevant dissolution to obtain IVIVC of solid dosage forms containing a poorly-soluble model compound.

Lue BM, Nielsen FS, Magnussen T, Schou HM, Kristensen K, Jacobsen LO, Müllertz A.

Eur J Pharm Biopharm. 2008 Jun;69(2):648-57. Epub 2007 Dec 25.PMID: 18280122 [PubMed - indexed for MEDLINE]Related articles

Predictors of mortality in patients with type 2 diabetes with or without diabetic nephropathy: a follow-up study.

Astrup AS, Nielsen FS, Rossing P, Ali S, Kastrup J, Smidt UM, Parving HH.

J Hypertens. 2007 Dec;25(12):2479-85.PMID: 17984670 [PubMed - indexed for MEDLINE]Related articles

Structural development of self nano emulsifying drug delivery systems (SNEDDS) during in vitro lipid digestion monitored by small-angle X-ray scattering.

Fatouros DG, Deen GR, Arleth L, Bergenstahl B, Nielsen FS, Pedersen JS, Mullertz A.

Pharm Res. 2007 Oct;24(10):1844-53. Epub 2007 Apr 26.PMID: 17458683 [PubMed - indexed for MEDLINE]Related articles

Characterization of prototype self-nanoemulsifying formulations of lipophilic compounds.

Nielsen FS, Gibault E, Ljusberg-Wahren H, Arleth L, Pedersen JS, Müllertz A.

J Pharm Sci. 2007 Apr;96(4):876-92.PMID: 17279513 [PubMed - indexed for MEDLINE]Related articles

Left ventricular hypertrophy in normoalbuminuric type 2 diabetic patients not taking antihypertensive treatment.

Sato A, Tarnow L, Nielsen FS, Knudsen E, Parving HH.

QJM. 2005 Dec;98(12):879-84. Epub 2005 Nov 4.PMID: 16272208 [PubMed - indexed for MEDLINE]Related articlesFree article

Crystallization and preliminary X-ray diffraction analysis of the heterotetrameric dihydroorotate dehydrogenase B of Lactococcus lactis, a flavoprotein enzyme system consisting of two PyrDB subunits and two iron-sulfur cluster containing PyrK subunits.

Rowland P, Nielsen FS, Jensen KF, Larsen S.

Acta Crystallogr D Biol Crystallogr. 1997 Nov 1;53(Pt 6):802-4.PMID: 15299876 [PubMed]Related articles

Insertion of foreign T cell epitopes in human tumor necrosis factor alpha with minimal effect on protein structure and biological activity.

Nielsen FS, Sauer J, Bäcklund J, Voldborg B, Gregorius K, Mouritsen S, Bratt T.

J Biol Chem. 2004 Aug 6;279(32):33593-600. Epub 2004 Jun 1.PMID: 15173183 [PubMed - indexed for MEDLINE]Related articlesFree article

Myocardial perfusion in type 2 diabetes with left ventricular hypertrophy: normalisation by acute angiotensin-converting enzyme inhibition.

Hesse B, Meyer C, Nielsen FS, Sato A, Hove JD, Holm S, Bang LE, Kofoed KF, Svendsen TL, Parving HH, Opie LH.

Eur J Nucl Med Mol Imaging. 2004 Mar;31(3):362-8. Epub 2003 Dec 5.PMID: 14658015 [PubMed - indexed for MEDLINE]Related articles

Dipyridamole, cold pressor test, and demonstration of endothelial dysfunction: a PET study of myocardial perfusion in diabetes.

Kjaer A, Meyer C, Nielsen FS, Parving HH, Hesse B.

J Nucl Med. 2003 Jan;44(1):19-23.PMID: 12515871 [PubMed - indexed for MEDLINE]Related articlesFree article

Preventing diabetic nephropathy: an audit.

Hansen HP, Lund SS, Rossing P, Tarnow L, Nielsen FS, Jensen T, Parving HH.

Scand J Clin Lab Invest. 2001;61(6):471-7.PMID: 11681537 [PubMed - indexed for MEDLINE]Related articles

Diabetic nephropathy in non-insulin dependent diabetes mellitus. Cardiovascular risk factors and antihypertensive treatment.

Nielsen FS.

Dan Med Bull. 2000 Sep;47(4):249-70. Review. No abstract available. PMID: 11064829 [PubMed - indexed for MEDLINE]Related articles

Cardiovascular morbidity and early mortality cluster in parents of type 1 diabetic patients with diabetic nephropathy.

Tarnow L, Rossing P, Nielsen FS, Fagerudd JA, Poirier O, Parving HH.

Diabetes Care. 2000 Jan;23(1):30-3.PMID: 10857964 [PubMed - indexed for MEDLINE]Related articlesFree article

Biochemical characterization of the heteromeric Bacillus subtilis dihydroorotate dehydrogenase and its isolated subunits.

Kahler AE, Nielsen FS, Switzer RL.

Arch Biochem Biophys. 1999 Nov 15;371(2):191-201.PMID: 10545205 [PubMed - indexed for MEDLINE]Related articles

Increased sympathetic activity during sleep and nocturnal hypertension in Type 2 diabetic patients with diabetic nephropathy.

Nielsen FS, Hansen HP, Jacobsen P, Rossing P, Smidt UM, Christensen NJ, Pevet P, Vivien-Roels B, Parving HH.

Diabet Med. 1999 Jul;16(7):555-62.PMID: 10445830 [PubMed - indexed for MEDLINE]Related articles

Natural course of kidney function in Type 2 diabetic patients with diabetic nephropathy.

Christensen PK, Rossing P, Nielsen FS, Parving HH.

Diabet Med. 1999 May;16(5):388-94.PMID: 10342338 [PubMed - indexed for MEDLINE]Related articles

Effects of nisoldipine and lisinopril on left ventricular mass and function in diabetic nephropathy.

Tarnow L, Sato A, Ali S, Rossing P, Nielsen FS, Parving HH.

Diabetes Care. 1999 Mar;22(3):491-4.PMID: 10097934 [PubMed - indexed for MEDLINE]Related articlesFree article

Cyclosporine nephrotoxicity in type 1 diabetic patients. A 7-year follow-up study.

Parving HH, Tarnow L, Nielsen FS, Rossing P, Mandrup-Poulsen T, Osterby R, Nerup J.

Diabetes Care. 1999 Mar;22(3):478-83.PMID: 10097932 [PubMed - indexed for MEDLINE]Related articlesFree article

The crystal structure of Lactococcus lactis dihydroorotate dehydrogenase A complexed with the enzyme reaction product throws light on its enzymatic function.

Rowland P, Björnberg O, Nielsen FS, Jensen KF, Larsen S.

Protein Sci. 1998 Jun;7(6):1269-79.PMID: 9655329 [PubMed - indexed for MEDLINE]Related articlesFree article

Beneficial impact of ramipril on left ventricular hypertrophy in normotensive nonalbuminuric NIDDM patients.

Nielsen FS, Sato A, Ali S, Tarnow L, Smidt UM, Kastrup J, Parving HH.

Diabetes Care. 1998 May;21(5):804-9.PMID: 9589245 [PubMed - indexed for MEDLINE]Related articlesFree article

Predisposition to essential hypertension and development of diabetic nephropathy in IDDM patients.

Fagerudd JA, Tarnow L, Jacobsen P, Stenman S, Nielsen FS, Pettersson-Fernholm KJ, Grönhagen-Riska C, Parving HH, Groop PH.

Diabetes. 1998 Mar;47(3):439-44.PMID: 9519751 [PubMed - indexed for MEDLINE]Related articlesFree article

Kidney function after withdrawal of long-term antihypertensive treatment in diabetic nephropathy.

Hansen HP, Nielsen FS, Rossing P, Jacobsen P, Jensen BR, Parving HH.

Kidney Int Suppl. 1997 Dec;63:S49-53.PMID: 9407421 [PubMed - indexed for MEDLINE]Related articles

Lisinopril improves endothelial dysfunction in hypertensive NIDDM subjects with diabetic nephropathy.

Nielsen FS, Rossing P, Gall MA, Smidt UM, Chen JW, Sato A, Parving HH.

Scand J Clin Lab Invest. 1997 Aug;57(5):427-34.PMID: 9279969 [PubMed - indexed for MEDLINE]Related articles

Left ventricular hypertrophy in non-insulin-dependent diabetic patients with and without diabetic nephropathy.

Nielsen FS, Ali S, Rossing P, Bang LE, Svendsen TL, Gall MA, Smidt UM, Kastrup J, Parving HH.

Diabet Med. 1997 Jul;14(7):538-46.PMID: 9223391 [PubMed - indexed for MEDLINE]Related articles

Long-term effect of lisinopril and atenolol on kidney function in hypertensive NIDDM subjects with diabetic nephropathy.

Nielsen FS, Rossing P, Gall MA, Skøtt P, Smidt UM, Parving HH.

Diabetes. 1997 Jul;46(7):1182-8.PMID: 9200654 [PubMed - indexed for MEDLINE]Related articles

Polymorphisms in the interleukin-1 gene cluster do not contribute to the genetic susceptibility of diabetic nephropathy in Caucasian patients with IDDM.

Tarnow L, Pociot F, Hansen PM, Rossing P, Nielsen FS, Hansen BV, Parving HH.

Diabetes. 1997 Jun;46(6):1075-6. No abstract available. PMID: 9166682 [PubMed - indexed for MEDLINE]Related articles

White coat hypertension in NIDDM patients with and without incipient and overt diabetic nephropathy.

Nielsen FS, Gaede P, Vedel P, Pedersen O, Parving HH.

Diabetes Care. 1997 May;20(5):859-63.PMID: 9135956 [PubMed - indexed for MEDLINE]Related articles

Differences between nisoldipine and lisinopril on glomerular filtration rates and albuminuria in hypertensive IDDM patients with diabetic nephropathy during the first year of treatment.

Rossing P, Tarnow L, Boelskifte S, Jensen BR, Nielsen FS, Parving HH.

Diabetes. 1997 Mar;46(3):481-7.PMID: 9032106 [PubMed - indexed for MEDLINE]Related articles

The crystal structure of the flavin containing enzyme dihydroorotate dehydrogenase A from Lactococcus lactis.

Rowland P, Nielsen FS, Jensen KF, Larsen S.

Structure. 1997 Feb 15;5(2):239-52.PMID: 9032071 [PubMed - indexed for MEDLINE]Related articles

[Low birth weight--increased risk of diabetic nephropathies?]

Rossing P, Tarnow L, Nielsen FS, Hansen BV, Brenner BM, Parving HH.

Ugeskr Laeger. 1996 Dec 30;159(1):41-4. Danish. PMID: 9012073 [PubMed - indexed for MEDLINE]Related articles

Macro-microangiopathy and endothelial dysfunction in NIDDM patients with and without diabetic nephropathy.

Parving HH, Nielsen FS, Bang LE, Smidt UM, Svendsen TL, Chen JW, Gall MA, Rossing P.

Diabetologia. 1996 Dec;39(12):1590-7.PMID: 8960847 [PubMed - indexed for MEDLINE]Related articles

Glomerular hyperfiltration in microalbuminuric NIDDM patients.

Vedel P, Obel J, Nielsen FS, Bang LE, Svendsen TL, Pedersen OB, Parving HH.

Diabetologia. 1996 Dec;39(12):1584-9.PMID: 8960846 [PubMed - indexed for MEDLINE]Related articles

Increased plasma apolipoprotein (a) levels in IDDM patients with diabetic nephropathy.

Tarnow L, Rossing P, Nielsen FS, Hansen BV, Dyerberg J, Parving HH.

Diabetes Care. 1996 Dec;19(12):1382-7.PMID: 8941468 [PubMed - indexed for MEDLINE]Related articles

[Albuminuria and glycemic control. The significance for mortality in non-insulin-dependent diabetes mellitus]

Gall MA, Borch-Johnsen K, Hougaard P, Nielsen FS, Parving HH.

Ugeskr Laeger. 1996 Nov 25;158(48):6907-11. Danish. PMID: 8984753 [PubMed - indexed for MEDLINE]Related articles

The B form of dihydroorotate dehydrogenase from Lactococcus lactis consists of two different subunits, encoded by the pyrDb and pyrK genes, and contains FMN, FAD, and [FeS] redox centers.

Nielsen FS, Andersen PS, Jensen KF.

J Biol Chem. 1996 Nov 15;271(46):29359-65.PMID: 8910599 [PubMed - indexed for MEDLINE]Related articlesFree article

Fish oil in diabetic nephropathy.

Rossing P, Hansen BV, Nielsen FS, Myrup B, Hølmer G, Parving HH.

Diabetes Care. 1996 Nov;19(11):1214-9.PMID: 8908382 [PubMed - indexed for MEDLINE]Related articles

Circadian rhythm of arterial blood pressure and albuminuria in diabetic nephropathy.

Hansen HP, Rossing P, Tarnow L, Nielsen FS, Jensen BR, Parving HH.

Kidney Int. 1996 Aug;50(2):579-85.PMID: 8840289 [PubMed - indexed for MEDLINE]Related articles

Angiotensin-II type 1 receptor gene polymorphism and diabetic microangiopathy.

Tarnow L, Cambien F, Rossing P, Nielsen FS, Hansen BV, Ricard S, Poirer O, Parving HH.

Nephrol Dial Transplant. 1996 Jun;11(6):1019-23.PMID: 8671962 [PubMed - indexed for MEDLINE]Related articlesFree article

Purification and characterization of dihydroorotate dehydrogenase A from Lactococcus lactis, crystallization and preliminary X-ray diffraction studies of the enzyme.

Nielsen FS, Rowland P, Larsen S, Jensen KF.

Protein Sci. 1996 May;5(5):852-6.PMID: 8732756 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensinogen gene polymorphisms in IDDM patients with diabetic nephropathy.

Tarnow L, Cambien F, Rossing P, Nielsen FS, Hansen BV, Ricard S, Poirier O, Parving HH.

Diabetes. 1996 Mar;45(3):367-369.PMID: 8593944 [PubMed - indexed for MEDLINE]Related articles

Low birth weight. A risk factor for development of diabetic nephropathy?

Rossing P, Tarnow L, Nielsen FS, Hansen BV, Brenner BM, Parving HH.

Diabetes. 1995 Dec;44(12):1405-7.PMID: 7589846 [PubMed - indexed for MEDLINE]Related articles

Acquired oligonephropathy and diabetic nephropathy.

Nielsen FS, Gall MA, Parving HH.

Am J Kidney Dis. 1995 Dec;26(6):898-903.PMID: 7503063 [PubMed - indexed for MEDLINE]Related articles

Albuminuria and poor glycemic control predict mortality in NIDDM.

Gall MA, Borch-Johnsen K, Hougaard P, Nielsen FS, Parving HH.

Diabetes. 1995 Nov;44(11):1303-9.PMID: 7589828 [PubMed - indexed for MEDLINE]Related articles

On the mechanisms of blunted nocturnal decline in arterial blood pressure in NIDDM patients with diabetic nephropathy.

Nielsen FS, Rossing P, Bang LE, Svendsen TL, Gall MA, Smidt UM, Parving HH.

Diabetes. 1995 Jul;44(7):783-9.PMID: 7789646 [PubMed - indexed for MEDLINE]Related articles

Insertion/deletion polymorphism in the angiotensin-I-converting enzyme gene is associated with coronary heart disease in IDDM patients with diabetic nephropathy.

Tarnow L, Cambien F, Rossing P, Nielsen FS, Hansen BV, Lecerf L, Poirier O, Danilov S, Boelskifte S, Borch-Johnsen K.

Diabetologia. 1995 Jul;38(7):798-803.PMID: 7556981 [PubMed - indexed for MEDLINE]Related articles

Increased glomerular filtration rate after withdrawal of long-term antihypertensive treatment in diabetic nephropathy.

Hansen HP, Rossing P, Tarnow L, Nielsen FS, Jensen BR, Parving HH.

Kidney Int. 1995 Jun;47(6):1726-31.PMID: 7643542 [PubMed - indexed for MEDLINE]Related articles

Lack of relationship between an insertion/deletion polymorphism in the angiotensin I-converting enzyme gene and diabetic nephropathy and proliferative retinopathy in IDDM patients.

Tarnow L, Cambien F, Rossing P, Nielsen FS, Hansen BV, Lecerf L, Poirier O, Danilov S, Parving HH.

Diabetes. 1995 May;44(5):489-94.PMID: 7729604 [PubMed - indexed for MEDLINE]Related articles

Long-term comparison of human insulin analogue B10Asp and soluble human insulin in IDDM patients on a basal/bolus insulin regimen.

Nielsen FS, Jørgensen LN, Ipsen M, Voldsgaard AI, Parving HH.

Diabetologia. 1995 May;38(5):592-8.PMID: 7489843 [PubMed - indexed for MEDLINE]Related articles