PubMed

Immune escape mechanisms of intraocular tumors.

Niederkorn JY.

Prog Retin Eye Res. 2009 Sep;28(5):329-47. Epub 2009 Jun 27. Review.PMID: 19563908 [PubMed - indexed for MEDLINE]Related articles

Inhibition of Chemokine Receptor Expression on Uveal Melanomas by CXCR4 siRNA Blocks Tumor Cell Invasion and Liver Metastasis of Uveal Melanoma Cells.

Li H, Yang W, Chen PW, Alizadeh H, Niederkorn JY.

Invest Ophthalmol Vis Sci. 2009 Jun 24. [Epub ahead of print]PMID: 19553629 [PubMed - as supplied by publisher]Related articles

Allergic airway hyperreactivity increases the risk for corneal allograft rejection.

Niederkorn JY, Chen PW, Mellon J, Stevens C, Mayhew E.

Am J Transplant. 2009 May;9(5):1017-26.PMID: 19422331 [PubMed - indexed for MEDLINE]Related articles

IL-17 disrupts corneal barrier following desiccating stress.

De Paiva CS, Chotikavanich S, Pangelinan SB, Pitcher JD 3rd, Fang B, Zheng X, Ma P, Farley WJ, Siemasko KF, Niederkorn JY, Stern ME, Li DQ, Pflugfelder SC.

Mucosal Immunol. 2009 May;2(3):243-53. Epub 2009 Feb 25.PMID: 19242409 [PubMed - indexed for MEDLINE]Related articles

PD-L1 expression on human ocular cells and its possible role in regulating immune-mediated ocular inflammation.

Yang W, Li H, Chen PW, Alizadeh H, He Y, Hogan RN, Niederkorn JY.

Invest Ophthalmol Vis Sci. 2009 Jan;50(1):273-80. Epub 2008 Sep 12.PMID: 18791172 [PubMed - indexed for MEDLINE]Related articles

Immune regulatory mechanisms in allergic conjunctivitis: insights from mouse models.

Niederkorn JY.

Curr Opin Allergy Clin Immunol. 2008 Oct;8(5):472-6. Review.PMID: 18769204 [PubMed - indexed for MEDLINE]Related articlesFree article

In vitro expanded CD4+CD25+Foxp3+ regulatory T cells maintain a normal phenotype and suppress immune-mediated ocular surface inflammation.

Siemasko KF, Gao J, Calder VL, Hanna R, Calonge M, Pflugfelder SC, Niederkorn JY, Stern ME.

Invest Ophthalmol Vis Sci. 2008 Dec;49(12):5434-40. Epub 2008 Jul 24.PMID: 18658093 [PubMed - indexed for MEDLINE]Related articles

Modulation of corneal and stromal matrix metalloproteinase by the mannose-induced Acanthamoeba cytolytic protein.

Alizadeh H, Li H, Neelam S, Niederkorn JY.

Exp Eye Res. 2008 Sep;87(3):286-91. Epub 2008 Jun 25.PMID: 18627771 [PubMed - indexed for MEDLINE]Related articlesFree article

Emerging concepts in CD8(+) T regulatory cells.

Niederkorn JY.

Curr Opin Immunol. 2008 Jun;20(3):327-31. Epub 2008 Apr 10. Review.PMID: 18406591 [PubMed - indexed for MEDLINE]Related articlesFree article

PD-L1: PD-1 interaction contributes to the functional suppression of T-cell responses to human uveal melanoma cells in vitro.

Yang W, Chen PW, Li H, Alizadeh H, Niederkorn JY.

Invest Ophthalmol Vis Sci. 2008 Jun;49(6):2518-25. Epub 2008 Feb 22.PMID: 18296654 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential expression of chemokine receptors on uveal melanoma cells and their metastases.

Li H, Alizadeh H, Niederkorn JY.

Invest Ophthalmol Vis Sci. 2008 Feb;49(2):636-43.PMID: 18235009 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of activated macrophages in Acanthamoeba keratitis.

Alizadeh H, Neelam S, Niederkorn JY.

J Parasitol. 2007 Oct;93(5):1114-20.PMID: 18163346 [PubMed - indexed for MEDLINE]Related articles

Immune mechanisms of corneal allograft rejection.

Niederkorn JY.

Curr Eye Res. 2007 Dec;32(12):1005-16. Review.PMID: 18085464 [PubMed - indexed for MEDLINE]Related articles

Effect of immunization with the mannose-induced Acanthamoeba protein and Acanthamoeba plasminogen activator in mitigating Acanthamoeba keratitis.

Alizadeh H, Neelam S, Niederkorn JY.

Invest Ophthalmol Vis Sci. 2007 Dec;48(12):5597-604.PMID: 18055809 [PubMed - indexed for MEDLINE]Related articlesFree article

CD4+ T-cell-dependent tumour rejection in an immune-privileged environment requires macrophages.

Dace DS, Chen PW, Niederkorn JY.

Immunology. 2008 Mar;123(3):367-77. Epub 2007 Oct 17.PMID: 17944931 [PubMed - indexed for MEDLINE]Related articlesFree article

Uveal melanoma expression of indoleamine 2,3-deoxygenase: establishment of an immune privileged environment by tryptophan depletion.

Chen PW, Mellon JK, Mayhew E, Wang S, He YG, Hogan N, Niederkorn JY.

Exp Eye Res. 2007 Nov;85(5):617-25. Epub 2007 Jul 25.PMID: 17870068 [PubMed - indexed for MEDLINE]Related articlesFree article

Expansion of B cells is necessary for the induction of T-cell tolerance elicited through the anterior chamber of the eye.

Ashour HM, Niederkorn JY.

Int Arch Allergy Immunol. 2007;144(4):343-6. Epub 2007 Jul 16.PMID: 17671393 [PubMed - indexed for MEDLINE]Related articles

Induction of anterior chamber-associated immune deviation requires an intact, functional spleen. 1981.

Streilein JW, Niederkorn JY.

Ocul Immunol Inflamm. 2007 May-Jun;15(3):187-94. No abstract available. PMID: 17613833 [PubMed - indexed for MEDLINE]Related articles

Dry eye-induced conjunctival epithelial squamous metaplasia is modulated by interferon-gamma.

De Paiva CS, Villarreal AL, Corrales RM, Rahman HT, Chang VY, Farley WJ, Stern ME, Niederkorn JY, Li DQ, Pflugfelder SC.

Invest Ophthalmol Vis Sci. 2007 Jun;48(6):2553-60.PMID: 17525184 [PubMed - indexed for MEDLINE]Related articlesFree article

CD8+ T cells circumvent immune privilege in the eye and mediate intraocular tumor rejection by a TNF-alpha-dependent mechanism.

Dace DS, Chen PW, Niederkorn JY.

J Immunol. 2007 May 15;178(10):6115-22.PMID: 17475837 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunogenicity and immune privilege of corneal allografts.

Hori J, Niederkorn JY.

Chem Immunol Allergy. 2007;92:290-9. Review.PMID: 17264504 [PubMed - indexed for MEDLINE]Related articles

Regulatory T cells and the eye.

Niederkorn JY.

Chem Immunol Allergy. 2007;92:131-9. Review.PMID: 17264489 [PubMed - indexed for MEDLINE]Related articles

The induction of anterior chamber-associated immune deviation.

Niederkorn JY.

Chem Immunol Allergy. 2007;92:27-35. Review.PMID: 17264480 [PubMed - indexed for MEDLINE]Related articles

Regional immunity and immune privilege.

Kaplan HJ, Niederkorn JY.

Chem Immunol Allergy. 2007;92:11-26. Review.PMID: 17264479 [PubMed - indexed for MEDLINE]Related articles

Rationale for immune response and the eye.

Niederkorn JY, Kaplan HJ.

Chem Immunol Allergy. 2007;92:1-3. No abstract available. PMID: 17264477 [PubMed - indexed for MEDLINE]Related articles

Evaluation of ocular surface inflammation in the presence of dry eye and allergic conjunctival disease.

Stern ME, Siemasko KF, Gao J, Calonge M, Niederkorn JY, Pflugfelder SC.

Ocul Surf. 2005 Oct;3(4 Suppl):S161-4.PMID: 17216110 [PubMed]Related articles

Corneal immune privilege.

Niederkorn JY.

Ocul Surf. 2005 Oct;3(4 Suppl):S158-60.PMID: 17216109 [PubMed]Related articles

Pathways of corneal and ocular surface inflammation: a perspective from the cullen symposium.

McDermott AM, Perez V, Huang AJ, Pflugfelder SC, Stern ME, Baudouin C, Beuerman RW, Burns AR, Calder VL, Calonge M, Chodosh J, Coster DJ, Dana R, Hazlett LD, Jones DB, Kim SK, Knop E, Li DQ, Mitchell BM, Niederkorn JY, Pearlman E, Wilhelmus KR, Kurie E.

Ocul Surf. 2005 Oct;3(4 Suppl):S131-8.PMID: 17216102 [PubMed]Related articles

Gammadelta T cells promote anterior chamber-associated immune deviation and immune privilege through their production of IL-10.

Ashour HM, Niederkorn JY.

J Immunol. 2006 Dec 15;177(12):8331-7.PMID: 17142729 [PubMed - indexed for MEDLINE]Related articlesFree article

Ocular immune privilege is circumvented by CD4+ T cells, leading to the rejection of intraocular tumors in an IFN-{gamma}-dependent manner.

Dace DS, Chen PW, Alizadeh H, Niederkorn JY.

J Leukoc Biol. 2007 Feb;81(2):421-9. Epub 2006 Oct 31.PMID: 17077163 [PubMed - indexed for MEDLINE]Related articlesFree article

Intracorneal instillation of latex beads induces macrophage-dependent protection against Acanthamoeba keratitis.

Clarke DW, Alizadeh H, Niederkorn JY.

Invest Ophthalmol Vis Sci. 2006 Nov;47(11):4917-25.PMID: 17065507 [PubMed - indexed for MEDLINE]Related articlesFree article

Oral immunization with Acanthamoeba castellanii mannose-binding protein ameliorates amoebic keratitis.

Garate M, Alizadeh H, Neelam S, Niederkorn JY, Panjwani N.

Infect Immun. 2006 Dec;74(12):7032-4. Epub 2006 Sep 18.PMID: 16982837 [PubMed - indexed for MEDLINE]Related articlesFree article

The immunobiology of Acanthamoeba keratitis.

Clarke DW, Niederkorn JY.

Microbes Infect. 2006 Apr;8(5):1400-5. Epub 2006 Feb 9. Review.PMID: 16697233 [PubMed - indexed for MEDLINE]Related articles

Peripheral tolerance via the anterior chamber of the eye: role of B cells in MHC class I and II antigen presentation.

Ashour HM, Niederkorn JY.

J Immunol. 2006 May 15;176(10):5950-7.PMID: 16670303 [PubMed - indexed for MEDLINE]Related articlesFree article

CD4+ T-cell-independent rejection of corneal allografts.

Niederkorn JY, Stevens C, Mellon J, Mayhew E.

Transplantation. 2006 Apr 27;81(8):1171-8.PMID: 16641604 [PubMed - indexed for MEDLINE]Related articles

Downregulation of survivin expression enhances sensitivity of cultured uveal melanoma cells to cisplatin treatment.

Li H, Niederkorn JY, Neelam S, Alizadeh H.

Exp Eye Res. 2006 Jul;83(1):176-82. Epub 2006 Apr 11.PMID: 16584731 [PubMed - indexed for MEDLINE]Related articles

See no evil, hear no evil, do no evil: the lessons of immune privilege.

Niederkorn JY.

Nat Immunol. 2006 Apr;7(4):354-9. Review.PMID: 16550198 [PubMed - indexed for MEDLINE]Related articles

Desiccating stress induces T cell-mediated Sjögren's Syndrome-like lacrimal keratoconjunctivitis.

Niederkorn JY, Stern ME, Pflugfelder SC, De Paiva CS, Corrales RM, Gao J, Siemasko K.

J Immunol. 2006 Apr 1;176(7):3950-7.PMID: 16547229 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential roles of CD8+ and CD8- T lymphocytes in corneal allograft rejection in 'high-risk' hosts.

Niederkorn JY, Stevens C, Mellon J, Mayhew E.

Am J Transplant. 2006 Apr;6(4):705-13.PMID: 16539627 [PubMed - indexed for MEDLINE]Related articles

The pathophysiology of Acanthamoeba keratitis.

Clarke DW, Niederkorn JY.

Trends Parasitol. 2006 Apr;22(4):175-80. Epub 2006 Feb 24. Review.PMID: 16500148 [PubMed - indexed for MEDLINE]Related articles

Immune privilege of the eye and fetus: parallel universes?

Niederkorn JY, Wang S.

Transplantation. 2005 Nov 15;80(9):1139-44. Review.PMID: 16314777 [PubMed - indexed for MEDLINE]Related articles

Effect of an anti-CD54 (ICAM-1) monoclonal antibody (UV3) on the growth of human uveal melanoma cells transplanted heterotopically and orthotopically in SCID mice.

Wang S, Coleman EJ, Pop LM, Brooks KJ, Vitetta ES, Niederkorn JY.

Int J Cancer. 2006 Feb 15;118(4):932-41.PMID: 16152588 [PubMed - indexed for MEDLINE]Related articles

A renewed appreciation for ocular immune privilege.

Niederkorn JY.

Arch Soc Esp Oftalmol. 2005 Aug;80(8):437-8; 439-40. English, Spanish. No abstract available. PMID: 16136394 [PubMed - indexed for MEDLINE]Related articlesFree article

The Th1/Th2 paradigm in ocular allergy.

Stern ME, Siemasko KF, Niederkorn JY.

Curr Opin Allergy Clin Immunol. 2005 Oct;5(5):446-50. Review.PMID: 16131922 [PubMed - indexed for MEDLINE]Related articles

Role of interferon-gamma in a mouse model of allergic conjunctivitis.

Stern ME, Siemasko K, Gao J, Duong A, Beauregard C, Calder V, Niederkorn JY.

Invest Ophthalmol Vis Sci. 2005 Sep;46(9):3239-46.PMID: 16123425 [PubMed - indexed for MEDLINE]Related articlesFree article

Failure of Acanthamoeba castellanii to produce intraocular infections.

Clarke DW, Alizadeh H, Niederkorn JY.

Invest Ophthalmol Vis Sci. 2005 Jul;46(7):2472-8.PMID: 15980238 [PubMed - indexed for MEDLINE]Related articlesFree article

Cutting edge: atopy promotes Th2 responses to alloantigens and increases the incidence and tempo of corneal allograft rejection.

Beauregard C, Stevens C, Mayhew E, Niederkorn JY.

J Immunol. 2005 Jun 1;174(11):6577-81.PMID: 15905494 [PubMed - indexed for MEDLINE]Related articlesFree article

Resistance and susceptibility of human uveal melanoma cells to TRAIL-induced apoptosis.

Li H, Niederkorn JY, Neelam S, Alizadeh H.

Arch Ophthalmol. 2005 May;123(5):654-61.PMID: 15883285 [PubMed - indexed for MEDLINE]Related articles

Immunology of intraocular tumors.

Niederkorn JY, Wang S.

Ocul Immunol Inflamm. 2005 Feb;13(1):105-10. Review.PMID: 15835077 [PubMed - indexed for MEDLINE]Related articles

Immunosuppressive factors secreted by human amniotic epithelial cells.

Li H, Niederkorn JY, Neelam S, Mayhew E, Word RA, McCulley JP, Alizadeh H.

Invest Ophthalmol Vis Sci. 2005 Mar;46(3):900-7.PMID: 15728546 [PubMed - indexed for MEDLINE]Related articlesFree article