PubMed

Acute infection with a single hepatitis C virus strain in dialysis patients: Analysis of adaptive immune response and viral variability.

Weseslindtner L, Neumann-Haefelin C, Viazov S, Haberstroh A, Kletzmayr J, Aberle JH, Timm J, Ross SR, Klauser-Braun R, Baumert TF, Roggendorf M, Thimme R, Holzmann H.

J Hepatol. 2009 Apr;50(4):693-704. Epub 2009 Jan 27.PMID: 19231006 [PubMed - indexed for MEDLINE]Related articles

Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27-restricted human immune response.

Dazert E, Neumann-Haefelin C, Bressanelli S, Fitzmaurice K, Kort J, Timm J, McKiernan S, Kelleher D, Gruener N, Tavis JE, Rosen HR, Shaw J, Bowness P, Blum HE, Klenerman P, Bartenschlager R, Thimme R.

J Clin Invest. 2009 Feb;119(2):376-86. doi: 10.1172/JCI36587. Epub 2009 Jan 12.PMID: 19139562 [PubMed - indexed for MEDLINE]Related articlesFree article

Comprehensive analysis of the alpha-fetoprotein-specific CD8+ T cell responses in patients with hepatocellular carcinoma.

Thimme R, Neagu M, Boettler T, Neumann-Haefelin C, Kersting N, Geissler M, Makowiec F, Obermaier R, Hopt UT, Blum HE, Spangenberg HC.

Hepatology. 2008 Dec;48(6):1821-33.PMID: 19003875 [PubMed - indexed for MEDLINE]Related articles

[RNA interference as antiviral strategy]

Neumann-Haefelin C, Blum HE, Thimme R.

Dtsch Med Wochenschr. 2008 Nov;133(46):2407-9. Epub 2008 Nov 4. Review. German. PMID: 18988133 [PubMed - indexed for MEDLINE]Related articles

Adaptive immune responses to hepatitis C virus: from viral immunobiology to a vaccine.

Thimme R, Neumann-Haefelin C, Boettler T, Blum HE.

Biol Chem. 2008 May;389(5):457-67. Review.PMID: 18953713 [PubMed - indexed for MEDLINE]Related articles

Escape from HLA-B*08-restricted CD8 T cells by hepatitis C virus is associated with fitness costs.

Salloum S, Oniangue-Ndza C, Neumann-Haefelin C, Hudson L, Giugliano S, aus dem Siepen M, Nattermann J, Spengler U, Lauer GM, Wiese M, Klenerman P, Bright H, Scherbaum N, Thimme R, Roggendorf M, Viazov S, Timm J.

J Virol. 2008 Dec;82(23):11803-12. Epub 2008 Sep 24.PMID: 18815309 [PubMed - indexed for MEDLINE]Related articlesFree article

Reversal of visceral adiposity in candy-diet fed female Wistar rats by the CB1 receptor antagonist rimonabant.

Herling AW, Kilp S, Juretschke HP, Neumann-Haefelin C, Gerl M, Kramer W.

Int J Obes (Lond). 2008 Sep;32(9):1363-72. Epub 2008 Jul 15.PMID: 18626484 [PubMed - indexed for MEDLINE]Related articles

Virological and immunological determinants of intrahepatic virus-specific CD8+ T-cell failure in chronic hepatitis C virus infection.

Neumann-Haefelin C, Timm J, Spangenberg HC, Wischniowski N, Nazarova N, Kersting N, Roggendorf M, Allen TM, Blum HE, Thimme R.

Hepatology. 2008 Jun;47(6):1824-36.PMID: 18454507 [PubMed - indexed for MEDLINE]Related articles

Adaptive immune responses to hepatitis C virus: from viral immunobiology to a vaccine.

Thimme R, Neumann-Haefelin C, Boettler T, Blum HE.

Biol Chem. 2008 Mar 6. [Epub ahead of print]PMID: 18321220 [PubMed - as supplied by publisher]Related articles

Analysis of the evolutionary forces in an immunodominant CD8 epitope in hepatitis C virus at a population level.

Neumann-Haefelin C, Frick DN, Wang JJ, Pybus OG, Salloum S, Narula GS, Eckart A, Biezynski A, Eiermann T, Klenerman P, Viazov S, Roggendorf M, Thimme R, Reiser M, Timm J.

J Virol. 2008 Apr;82(7):3438-51. Epub 2008 Jan 23.PMID: 18216107 [PubMed - indexed for MEDLINE]Related articlesFree article

Scavenger receptor class B is required for hepatitis C virus uptake and cross-presentation by human dendritic cells.

Barth H, Schnober EK, Neumann-Haefelin C, Thumann C, Zeisel MB, Diepolder HM, Hu Z, Liang TJ, Blum HE, Thimme R, Lambotin M, Baumert TF.

J Virol. 2008 Apr;82(7):3466-79. Epub 2008 Jan 23.PMID: 18216094 [PubMed - indexed for MEDLINE]Related articlesFree article

Immune responses against HCV-NS3 after accidental infection with HCV-NS3 recombinant vaccinia virus.

Eisenbach C, Neumann-Haefelin C, Freyse A, Korsukéwitz T, Hoyler B, Stremmel W, Thimme R, Encke J.

J Viral Hepat. 2007 Nov;14(11):817-9. No abstract available. PMID: 17927619 [PubMed - indexed for MEDLINE]Related articles

Host and viral factors contributing to CD8+ T cell failure in hepatitis C virus infection.

Neumann-Haefelin C, Spangenberg HC, Blum HE, Thimme R.

World J Gastroenterol. 2007 Sep 28;13(36):4839-47. Review.PMID: 17828815 [PubMed - indexed for MEDLINE]Related articlesFree article

Absence of viral escape within a frequently recognized HLA-A26-restricted CD8+ T-cell epitope targeting the functionally constrained hepatitis C virus NS5A/5B cleavage site.

Neumann-Haefelin C, Killinger T, Timm J, Southwood S, McKinney D, Blum HE, Thimme R.

J Gen Virol. 2007 Jul;88(Pt 7):1986-91.PMID: 17554032 [PubMed - indexed for MEDLINE]Related articlesFree article

[Immunopathogenesis of viral hepatitis]

Neumann-Haefelin C, Thimme R.

Praxis (Bern 1994). 2007 Apr 4;96(14):545-51. Review. German. PMID: 17455566 [PubMed - indexed for MEDLINE]Related articles

Impact of the genetic restriction of virus-specific T-cell responses in hepatitis C virus infection.

Neumann-Haefelin C, Thimme R.

Genes Immun. 2007 Apr;8(3):181-92. Epub 2007 Jan 18. Review.PMID: 17230195 [PubMed - indexed for MEDLINE]Related articles

Analysis of CD127 and KLRG1 expression on hepatitis C virus-specific CD8+ T cells reveals the existence of different memory T-cell subsets in the peripheral blood and liver.

Bengsch B, Spangenberg HC, Kersting N, Neumann-Haefelin C, Panther E, von Weizsäcker F, Blum HE, Pircher H, Thimme R.

J Virol. 2007 Jan;81(2):945-53. Epub 2006 Nov 1.PMID: 17079288 [PubMed - indexed for MEDLINE]Related articlesFree article

Correlation between MR-spectroscopic rat hippocampal choline levels and phospholipase A2.

Sartorius A, Schloss P, Vollmayr B, Ende G, Neumann-Haefelin C, Hoehn M, Henn FA.

World J Biol Psychiatry. 2006;7(4):246-50.PMID: 17071545 [PubMed - indexed for MEDLINE]Related articles

[Immunological T cell analyses -- current state and clinical relevance]

Neumann-Haefelin C, Blum HE, Thimme R.

Dtsch Med Wochenschr. 2006 Jun 2;131(22):1273-8. Review. German. No abstract available. PMID: 16755424 [PubMed - indexed for MEDLINE]Related articles

Dominant influence of an HLA-B27 restricted CD8+ T cell response in mediating HCV clearance and evolution.

Neumann-Haefelin C, McKiernan S, Ward S, Viazov S, Spangenberg HC, Killinger T, Baumert TF, Nazarova N, Sheridan I, Pybus O, von Weizsäcker F, Roggendorf M, Kelleher D, Klenerman P, Blum HE, Thimme R.

Hepatology. 2006 Mar;43(3):563-72.PMID: 16496339 [PubMed - indexed for MEDLINE]Related articles

Muscle type-specific fatty acid metabolism in insulin resistance: an integrated in vivo study in Zucker diabetic fatty rats.

Beha A, Juretschke HP, Kuhlmann J, Neumann-Haefelin C, Belz U, Gerl M, Kramer W, Roden M, Herling AW.

Am J Physiol Endocrinol Metab. 2006 May;290(5):E989-97. Epub 2005 Dec 27.PMID: 16380389 [PubMed - indexed for MEDLINE]Related articlesFree article

Intrahepatic CD8+ T-cell failure during chronic hepatitis C virus infection.

Spangenberg HC, Viazov S, Kersting N, Neumann-Haefelin C, McKinney D, Roggendorf M, von Weizsäcker F, Blum HE, Thimme R.

Hepatology. 2005 Oct;42(4):828-37.PMID: 16175596 [PubMed - indexed for MEDLINE]Related articles

T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection.

Boettler T, Spangenberg HC, Neumann-Haefelin C, Panther E, Urbani S, Ferrari C, Blum HE, von Weizsäcker F, Thimme R.

J Virol. 2005 Jun;79(12):7860-7.PMID: 15919940 [PubMed - indexed for MEDLINE]Related articlesFree article

Correlation between insulin resistance and intramyocellular lipid levels in rats.

Kuhlmann J, Neumann-Haefelin C, Belz U, Kramer W, Juretschke HP, Herling AW.

Magn Reson Med. 2005 Jun;53(6):1275-82.PMID: 15906287 [PubMed - indexed for MEDLINE]Related articles

Uptake and presentation of hepatitis C virus-like particles by human dendritic cells.

Barth H, Ulsenheimer A, Pape GR, Diepolder HM, Hoffmann M, Neumann-Haefelin C, Thimme R, Henneke P, Klein R, Paranhos-Baccalà G, Depla E, Liang TJ, Blum HE, Baumert TF.

Blood. 2005 May 1;105(9):3605-14. Epub 2005 Jan 18.PMID: 15657184 [PubMed - indexed for MEDLINE]Related articlesFree article

T cell response in hepatitis C virus infection.

Neumann-Haefelin C, Blum HE, Chisari FV, Thimme R.

J Clin Virol. 2005 Feb;32(2):75-85. Review.PMID: 15653409 [PubMed - indexed for MEDLINE]Related articles

Multiple spin-echo spectroscopic imaging for rapid quantitative assessment of N-acetylaspartate and lactate in acute stroke.

Stengel A, Neumann-Haefelin T, Singer OC, Neumann-Haefelin C, Zanella FE, Lanfermann H, Pilatus U.

Magn Reson Med. 2004 Aug;52(2):228-38.PMID: 15282804 [PubMed - indexed for MEDLINE]Related articles

[Suppressor T-cells: immunologic regulator cells and clinical perspectives]

Neumann-Haefelin C, Spangenberg HC, Thimme R, Blum HE.

Dtsch Med Wochenschr. 2004 Jul 23;129(30):1627-30. Review. German. PMID: 15257502 [PubMed - indexed for MEDLINE]Related articles

Characterization of adenosine-A1 receptor-mediated antilipolysis in rats by tissue microdialysis, 1H-spectroscopy, and glucose clamp studies.

Schoelch C, Kuhlmann J, Gossel M, Mueller G, Neumann-Haefelin C, Belz U, Kalisch J, Biemer-Daub G, Kramer W, Juretschke HP, Herling AW.

Diabetes. 2004 Jul;53(7):1920-6.PMID: 15220221 [PubMed - indexed for MEDLINE]Related articlesFree article

[The role of the virus specific T-cell response in acute and chronic HBV and HCV infection]

Panther E, Spangenberg HC, Neumann-Haefelin C, Rösler K, Blum HE, von Weizsäcker F, Thimme R.

Z Gastroenterol. 2004 Jan;42(1):39-46. Review. German. PMID: 14997402 [PubMed - indexed for MEDLINE]Related articles

Muscle-type specific intramyocellular and hepatic lipid metabolism during starvation in wistar rats.

Neumann-Haefelin C, Beha A, Kuhlmann J, Belz U, Gerl M, Quint M, Biemer-Daub G, Broenstrup M, Stein M, Kleinschmidt E, Schaefer HL, Schmoll D, Kramer W, Juretschke HP, Herling AW.

Diabetes. 2004 Mar;53(3):528-34.PMID: 14988234 [PubMed - indexed for MEDLINE]Related articlesFree article

Specific creatine rise in learned helplessness induced by electroconvulsive shock treatment.

Sartorius A, Vollmayr B, Neumann-Haefelin C, Ende G, Hoehn M, Henn FA.

Neuroreport. 2003 Dec 2;14(17):2199-201.PMID: 14625447 [PubMed - indexed for MEDLINE]Related articles

In vivo neuroprotective effects of ACEA 1021 confirmed by magnetic resonance imaging in ischemic stroke.

Petty MA, Neumann-Haefelin C, Kalisch J, Sarhan S, Wettstein JG, Juretschke HP.

Eur J Pharmacol. 2003 Aug 1;474(1):53-62.PMID: 12909195 [PubMed - indexed for MEDLINE]Related articles

Determinants of intramyocellular lipid concentrations in rat hindleg muscle.

Neumann-Haefelin C, Kuhlmann J, Belz U, Kalisch J, Quint M, Gerl M, Juretschke HP, Herling AW.

Magn Reson Med. 2003 Aug;50(2):242-8.PMID: 12876699 [PubMed - indexed for MEDLINE]Related articles

Choline rise in the rat hippocampus induced by electroconvulsive shock treatment.

Sartorius A, Neumann-Haefelin C, Vollmayr B, Hoehn M, Henn FA.

Biol Psychiatry. 2003 Apr 1;53(7):620-3.PMID: 12679241 [PubMed - indexed for MEDLINE]Related articles

Intramyocellular lipid and insulin resistance: a longitudinal in vivo 1H-spectroscopic study in Zucker diabetic fatty rats.

Kuhlmann J, Neumann-Haefelin C, Belz U, Kalisch J, Juretschke HP, Stein M, Kleinschmidt E, Kramer W, Herling AW.

Diabetes. 2003 Jan;52(1):138-44.PMID: 12502504 [PubMed - indexed for MEDLINE]Related articlesFree article

Prediction of hemorrhagic transformation after thrombolytic therapy of clot embolism: an MRI investigation in rat brain.

Neumann-Haefelin C, Brinker G, Uhlenküken U, Pillekamp F, Hossmann KA, Hoehn M.

Stroke. 2002 May;33(5):1392-8.PMID: 11988620 [PubMed - indexed for MEDLINE]Related articlesFree article

SRP-dependent co-translational targeting and SecA-dependent translocation analyzed as individual steps in the export of a bacterial protein.

Neumann-Haefelin C, Schäfer U, Müller M, Koch HG.

EMBO J. 2000 Dec 1;19(23):6419-26.PMID: 11101515 [PubMed - indexed for MEDLINE]Related articlesFree article

In vitro studies with purified components reveal signal recognition particle (SRP) and SecA/SecB as constituents of two independent protein-targeting pathways of Escherichia coli.

Koch HG, Hengelage T, Neumann-Haefelin C, MacFarlane J, Hoffschulte HK, Schimz KL, Mechler B, Müller M.

Mol Biol Cell. 1999 Jul;10(7):2163-73.PMID: 10397756 [PubMed - indexed for MEDLINE]Related articlesFree article

[Poliomyelitis in the German Federal Republic 1974-1975 (author's transl)]

Neumann-Haefelin D, Neumann-Haefelin C, Baumeister HG, Knocke KW.

Dtsch Med Wochenschr. 1976 Sep 10;101(37):1343-5. German. PMID: 182446 [PubMed - indexed for MEDLINE]Related articles

[Passive immunization against rubella: studies on the effectiveness of rubella-immunoglobulin after intranasal infection with rubella vaccination virus]

Neumann-Haefelin D, Neumann-Haefelin Ch, Petersen EE, Luthardt T, Hass R.

Dtsch Med Wochenschr. 1975 Jan 31;100(5):177-81. German. PMID: 1112230 [PubMed - indexed for MEDLINE]Related articles

[Passive rubella prophylaxis. Influence of rubella-immune globulin on success rate of the immunization (author's transl)]

Luthardt T, Neumann-Haefelin C, Neumann-Haefelin D, Petersen EE, Haas R.

Dtsch Med Wochenschr. 1974 Jun 7;99(23):1243-5. German. No abstract available. PMID: 4843390 [PubMed - indexed for MEDLINE]Related articles

[Vaccination against rubella. A comparison of intranasal and subcutaneous aadministration of the vaccination strain RA 27-3 (author's transl)]

Petersen EE, Büche M, Doerr HW, Neumann-Haefelin C, Luthardt T, Göttsching C, Haas R.

Dtsch Med Wochenschr. 1973 Oct 5;98(40):1842-7. German. No abstract available. PMID: 4762037 [PubMed - indexed for MEDLINE]Related articles