PubMed

Shortcomings of current models of glucose-induced insulin secretion.

Henquin JC, Nenquin M, Ravier MA, Szollosi A.

Diabetes Obes Metab. 2009 Nov;11 Suppl 4:168-79.PMID: 19817799 [PubMed - in process]Related articles

Glucose controls cytosolic Ca2+ and insulin secretion in mouse islets lacking adenosine triphosphate-sensitive K+ channels owing to a knockout of the pore-forming subunit Kir6.2.

Ravier MA, Nenquin M, Miki T, Seino S, Henquin JC.

Endocrinology. 2009 Jan;150(1):33-45. Epub 2008 Sep 11.PMID: 18787024 [PubMed - indexed for MEDLINE]Related articles

Insulin secretion in islets from mice with a double knockout for the dense core vesicle proteins islet antigen-2 (IA-2) and IA-2beta.

Henquin JC, Nenquin M, Szollosi A, Kubosaki A, Notkins AL.

J Endocrinol. 2008 Mar;196(3):573-81.PMID: 18310453 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-induced cytosolic pH changes in beta-cells and insulin secretion are not causally related: studies in islets lacking the Na+/H+ exchangeR NHE1.

Stiernet P, Nenquin M, Moulin P, Jonas JC, Henquin JC.

J Biol Chem. 2007 Aug 24;282(34):24538-46. Epub 2007 Jun 28.PMID: 17599909 [PubMed - indexed for MEDLINE]Related articlesFree article

Nutrient control of insulin secretion in perifused adult pig islets.

Dufrane D, Nenquin M, Henquin JC.

Diabetes Metab. 2007 Dec;33(6):430-8. Epub 2007 Jun 20.PMID: 17584514 [PubMed - indexed for MEDLINE]Related articlesFree article

Overnight culture unmasks glucose-induced insulin secretion in mouse islets lacking ATP-sensitive K+ channels by improving the triggering Ca2+ signal.

Szollosi A, Nenquin M, Henquin JC.

J Biol Chem. 2007 May 18;282(20):14768-76. Epub 2007 Mar 27.PMID: 17389589 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose stimulates Ca2+ influx and insulin secretion in 2-week-old beta-cells lacking ATP-sensitive K+ channels.

Szollosi A, Nenquin M, Aguilar-Bryan L, Bryan J, Henquin JC.

J Biol Chem. 2007 Jan 19;282(3):1747-56. Epub 2006 Nov 30.PMID: 17138557 [PubMed - indexed for MEDLINE]Related articlesFree article

Nutrient control of insulin secretion in isolated normal human islets.

Henquin JC, Dufrane D, Nenquin M.

Diabetes. 2006 Dec;55(12):3470-7.PMID: 17130494 [PubMed - indexed for MEDLINE]Related articlesFree article

In vivo and in vitro glucose-induced biphasic insulin secretion in the mouse: pattern and role of cytoplasmic Ca2+ and amplification signals in beta-cells.

Henquin JC, Nenquin M, Stiernet P, Ahren B.

Diabetes. 2006 Feb;55(2):441-51.PMID: 16443779 [PubMed - indexed for MEDLINE]Related articlesFree article

Both triggering and amplifying pathways contribute to fuel-induced insulin secretion in the absence of sulfonylurea receptor-1 in pancreatic beta-cells.

Nenquin M, Szollosi A, Aguilar-Bryan L, Bryan J, Henquin JC.

J Biol Chem. 2004 Jul 30;279(31):32316-24. Epub 2004 Jun 1.PMID: 15175349 [PubMed - indexed for MEDLINE]Related articlesFree article

Hierarchy of the beta-cell signals controlling insulin secretion.

Henquin JC, Ravier MA, Nenquin M, Jonas JC, Gilon P.

Eur J Clin Invest. 2003 Sep;33(9):742-50. Review. No abstract available. PMID: 12925032 [PubMed - indexed for MEDLINE]Related articles

SERCA3 ablation does not impair insulin secretion but suggests distinct roles of different sarcoendoplasmic reticulum Ca(2+) pumps for Ca(2+) homeostasis in pancreatic beta-cells.

Arredouani A, Guiot Y, Jonas JC, Liu LH, Nenquin M, Pertusa JA, Rahier J, Rolland JF, Shull GE, Stevens M, Wuytack F, Henquin JC, Gilon P.

Diabetes. 2002 Nov;51(11):3245-53.PMID: 12401716 [PubMed - indexed for MEDLINE]Related articlesFree article

The elevation of glutamate content and the amplification of insulin secretion in glucose-stimulated pancreatic islets are not causally related.

Bertrand G, Ishiyama N, Nenquin M, Ravier MA, Henquin JC.

J Biol Chem. 2002 Sep 6;277(36):32883-91. Epub 2002 Jun 26.PMID: 12087106 [PubMed - indexed for MEDLINE]Related articlesFree article

Signals and pools underlying biphasic insulin secretion.

Henquin JC, Ishiyama N, Nenquin M, Ravier MA, Jonas JC.

Diabetes. 2002 Feb;51 Suppl 1:S60-7. Review.PMID: 11815460 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of protein synthesis sequentially impairs distinct steps of stimulus-secretion coupling in pancreatic beta cells.

Garcia-Barrado MJ, Ravier MA, Rolland JF, Gilon P, Nenquin M, Henquin JC.

Endocrinology. 2001 Jan;142(1):299-307.PMID: 11145593 [PubMed - indexed for MEDLINE]Related articlesFree article

The oscillatory behavior of pancreatic islets from mice with mitochondrial glycerol-3-phosphate dehydrogenase knockout.

Ravier MA, Eto K, Jonkers FC, Nenquin M, Kadowaki T, Henquin JC.

J Biol Chem. 2000 Jan 21;275(3):1587-93.PMID: 10636849 [PubMed - indexed for MEDLINE]Related articlesFree article

Unbound rather than total concentration and saturation rather than unsaturation determine the potency of fatty acids on insulin secretion.

Warnotte C, Nenquin M, Henquin JC.

Mol Cell Endocrinol. 1999 Jul 20;153(1-2):147-53.PMID: 10459862 [PubMed - indexed for MEDLINE]Related articles

Tolbutamide and diazoxide influence insulin secretion by changing the concentration but not the action of cytoplasmic Ca2+ in beta-cells.

Mariot P, Gilon P, Nenquin M, Henquin JC.

Diabetes. 1998 Mar;47(3):365-73.PMID: 9519741 [PubMed - indexed for MEDLINE]Related articlesFree article

Relative contribution of Ca2+-dependent and Ca2+-independent mechanisms to the regulation of insulin secretion by glucose.

Sato Y, Nenquin M, Henquin JC.

FEBS Lett. 1998 Jan 9;421(2):115-9.PMID: 9468290 [PubMed - indexed for MEDLINE]Related articles

No evidence for a role of reverse Na(+)-Ca2+ exchange in insulin release from mouse pancreatic islets.

Garcia-Barrado MJ, Gilon P, Sato Y, Nenquin M, Henquin JC.

Am J Physiol. 1996 Sep;271(3 Pt 1):E426-33.PMID: 8843734 [PubMed - indexed for MEDLINE]Related articles

Muscarinic stimulation exerts both stimulatory and inhibitory effects on the concentration of cytoplasmic Ca2+ in the electrically excitable pancreatic B-cell.

Gilon P, Nenquin M, Henquin JC.

Biochem J. 1995 Oct 1;311 ( Pt 1):259-67.PMID: 7575463 [PubMed - indexed for MEDLINE]Related articlesFree article

Multiple effects and stimulation of insulin secretion by the tyrosine kinase inhibitor genistein in normal mouse islets.

Jonas JC, Plant TD, Gilon P, Detimary P, Nenquin M, Henquin JC.

Br J Pharmacol. 1995 Feb;114(4):872-80.PMID: 7773549 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms of the stimulation of insulin release by saturated fatty acids. A study of palmitate effects in mouse beta-cells.

Warnotte C, Gilon P, Nenquin M, Henquin JC.

Diabetes. 1994 May;43(5):703-11.PMID: 8168648 [PubMed - indexed for MEDLINE]Related articles

Two sites of glucose control of insulin release with distinct dependence on the energy state in pancreatic B-cells.

Detimary P, Gilon P, Nenquin M, Henquin JC.

Biochem J. 1994 Feb 1;297 ( Pt 3):455-61.PMID: 8110181 [PubMed - indexed for MEDLINE]Related articlesFree article

Vanadate stimulation of insulin release in normal mouse islets.

Zhang AQ, Gao ZY, Gilon P, Nenquin M, Drews G, Henquin JC.

J Biol Chem. 1991 Nov 15;266(32):21649-56.PMID: 1657974 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms of the stimulation of insulin release by arginine-vasopressin in normal mouse islets.

Gao ZY, Drews G, Nenquin M, Plant TD, Henquin JC.

J Biol Chem. 1990 Sep 15;265(26):15724-30.PMID: 2203783 [PubMed - indexed for MEDLINE]Related articlesFree article

Galanin and epinephrine act on distinct receptors to inhibit insulin release by the same mechanisms including an increase in K+ permeability of the B-cell membrane.

Drews G, Debuyser A, Nenquin M, Henquin JC.

Endocrinology. 1990 Mar;126(3):1646-53.PMID: 1689655 [PubMed - indexed for MEDLINE]Related articles

Comparison of the inhibition of insulin release by activation of adenosine and alpha 2-adrenergic receptors in rat beta-cells.

Bertrand G, Nenquin M, Henquin JC.

Biochem J. 1989 Apr 1;259(1):223-8.PMID: 2470346 [PubMed - indexed for MEDLINE]Related articlesFree article

The muscarinic receptor subtype in mouse pancreatic B-cells.

Henquin JC, Nenquin M.

FEBS Lett. 1988 Aug 15;236(1):89-92.PMID: 3042468 [PubMed - indexed for MEDLINE]Related articles

Muscarinic control of pancreatic B cell function involves sodium-dependent depolarization and calcium influx.

Henquin JC, Garcia MC, Bozem M, Hermans MP, Nenquin M.

Endocrinology. 1988 May;122(5):2134-42.PMID: 3282876 [PubMed - indexed for MEDLINE]Related articles

Effects of acute sodium omission on insulin release, ionic flux and membrane potential in mouse pancreatic B-cells.

de Miguel R, Tamagawa T, Schmeer W, Nenquin M, Henquin JC.

Biochim Biophys Acta. 1988 Apr 25;969(2):198-207.PMID: 3281715 [PubMed - indexed for MEDLINE]Related articles

Stimulation of insulin release by benzoic acid derivatives related to the non-sulphonylurea moiety of glibenclamide: structural requirements and cellular mechanisms.

Henquin JC, Garrino MG, Nenquin M.

Eur J Pharmacol. 1987 Sep 11;141(2):243-51.PMID: 3119355 [PubMed - indexed for MEDLINE]Related articles

The ionic, electrical, and secretory effects of protein kinase C activation in mouse pancreatic B-cells: studies with a phorbol ester.

Bozem M, Nenquin M, Henquin JC.

Endocrinology. 1987 Sep;121(3):1025-33.PMID: 3304975 [PubMed - indexed for MEDLINE]Related articles

Distinct mechanisms for two amplification systems of insulin release.

Henquin JC, Bozem M, Schmeer W, Nenquin M.

Biochem J. 1987 Sep 1;246(2):393-9.PMID: 2825637 [PubMed - indexed for MEDLINE]Related articlesFree article

Magnesium uptake by pancreatic islet cells is modulated by stimulators and inhibitors of the B-cell function.

Henquin JC, Nenquin M, Awouters P, Cogneau M.

Eur J Biochem. 1986 Mar 17;155(3):653-7.PMID: 3514212 [PubMed - indexed for MEDLINE]Related articlesFree article

Pharmacological control of 86Rb efflux from mouse pancreatic islets.

Henquin JC, Garrino MG, Nenquin M, Paolisso G, Hermans M.

Adv Exp Med Biol. 1986;211:83-93. No abstract available. PMID: 2440254 [PubMed - indexed for MEDLINE]Related articles

Effects of a calcium channel agonist on the electrical, ionic and secretory events in mouse pancreatic B-cells.

Henquin JC, Schmeer W, Nenquin M, Meissner HP.

Biochem Biophys Res Commun. 1985 Sep 16;131(2):980-6.PMID: 3902016 [PubMed - indexed for MEDLINE]Related articles

Mechanism of the stimulation of insulin release in vitro by HB 699, a benzoic acid derivative similar to the non-sulphonylurea moiety of glibenclamide.

Garrino MG, Schmeer W, Nenquin M, Meissner HP, Henquin JC.

Diabetologia. 1985 Sep;28(9):697-703.PMID: 3934021 [PubMed - indexed for MEDLINE]Related articles

Nutrient insulin secretagogues decrease 45Ca2+ efflux from islet cells by a mechanism other than the inhibition of the Na+-Ca2+ countertransport.

Henquin JC, de Miguel R, Garrino MG, Hermans M, Nenquin M.

FEBS Lett. 1985 Jul 22;187(1):177-81.PMID: 3926535 [PubMed - indexed for MEDLINE]Related articles

Sparteine increases insulin release by decreasing the K+ permeability of the B-cell membrane.

Paolisso G, Nenquin M, Schmeer W, Mathot F, Meissner HP, Henquin JC.

Biochem Pharmacol. 1985 Jul 1;34(13):2355-61.PMID: 3893438 [PubMed - indexed for MEDLINE]Related articles

The effects of cesium chloride on insulin release, ionic fluxes and membrane potential in pancreatic B-cells.

Paolisso G, Nenquin M, Meissner HP, Henquin JC.

Biochim Biophys Acta. 1985 Feb 21;844(2):200-8.PMID: 3882155 [PubMed - indexed for MEDLINE]Related articles

Distinct effects of acetylcholine and glucose on 45calcium and 86rubidium efflux from mouse pancreatic islets.

Nenquin M, Awouters P, Mathot F, Henquin JC.

FEBS Lett. 1984 Oct 29;176(2):457-61.PMID: 6386527 [PubMed - indexed for MEDLINE]Related articles

Forskolin suppresses the slow cyclic variations of glucose-induced electrical activity in pancreatic B cells.

Henquin JC, Schmeer W, Nenquin M, Meissner HP.

Biochem Biophys Res Commun. 1984 May 16;120(3):797-803.PMID: 6329184 [PubMed - indexed for MEDLINE]Related articles

Glucose modulates Mg2+ fluxes in pancreatic islet cells.

Henquin JC, Tamagawa T, Nenquin M, Cogneau M.

Nature. 1983 Jan 6;301(5895):73-4.PMID: 6337339 [PubMed - indexed for MEDLINE]Related articles

Diazoxide and D600 inhibition of insulin release. Distinct mechanisms explain the specificity for different stimuli.

Henquin JC, Charles S, Nenquin M, Mathot F, Tamagawa T.

Diabetes. 1982 Sep;31(9):776-83. No abstract available. PMID: 6131003 [PubMed - indexed for MEDLINE]Related articles

Quinine-induced modifications of insulin release and glucose metabolism by isolated pancreatic islets.

Henquin JC, Horemans B, Nenquin M, Verniers J, Lambert AE.

FEBS Lett. 1975 Oct 1;57(3):280-4. No abstract available. PMID: 1102333 [PubMed - indexed for MEDLINE]Related articles