PubMed

Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes.

Nejentsev S, Walker N, Riches D, Egholm M, Todd JA.

Science. 2009 Apr 17;324(5925):387-9. Epub 2009 Mar 5.PMID: 19264985 [PubMed - indexed for MEDLINE]Related articlesFree article

MCP-1 promoter variant -362C associated with protection from pulmonary tuberculosis in Ghana, West Africa.

Thye T, Nejentsev S, Intemann CD, Browne EN, Chinbuah MA, Gyapong J, Osei I, Owusu-Dabo E, Zeitels LR, Herb F, Horstmann RD, Meyer CG.

Hum Mol Genet. 2009 Jan 15;18(2):381-8. Epub 2008 Oct 20.PMID: 18940815 [PubMed - indexed for MEDLINE]Related articles

Genetic association and expression studies indicate a role of toll-like receptor 8 in pulmonary tuberculosis.

Davila S, Hibberd ML, Hari Dass R, Wong HE, Sahiratmadja E, Bonnard C, Alisjahbana B, Szeszko JS, Balabanova Y, Drobniewski F, van Crevel R, van de Vosse E, Nejentsev S, Ottenhoff TH, Seielstad M.

PLoS Genet. 2008 Oct;4(10):e1000218. Epub 2008 Oct 10.PMID: 18927625 [PubMed - indexed for MEDLINE]Related articlesFree article

Sequencing-based genotyping and association analysis of the MICA and MICB genes in type 1 diabetes.

Field SF, Nejentsev S, Walker NM, Howson JM, Godfrey LM, Jolley JD, Hardy MP, Todd JA.

Diabetes. 2008 Jun;57(6):1753-6. Epub 2008 Mar 10.PMID: 18332098 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of association of the TIRAP (MAL) S180L variant and tuberculosis in three populations.

Nejentsev S, Thye T, Szeszko JS, Stevens H, Balabanova Y, Chinbuah AM, Hibberd M, van de Vosse E, Alisjahbana B, van Crevel R, Ottenhoff TH, Png E, Drobniewski F, Todd JA, Seielstad M, Horstmann RD.

Nat Genet. 2008 Mar;40(3):261-2; author reply 262-3. No abstract available. PMID: 18305471 [PubMed - indexed for MEDLINE]Related articles

Down-regulation of NKG2D and NKp80 ligands by Kaposi's sarcoma-associated herpesvirus K5 protects against NK cell cytotoxicity.

Thomas M, Boname JM, Field S, Nejentsev S, Salio M, Cerundolo V, Wills M, Lehner PJ.

Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1656-61. Epub 2008 Jan 29.PMID: 18230726 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of extended human leukocyte antigen haplotype association with Addison's disease in three populations.

Gombos Z, Hermann R, Kiviniemi M, Nejentsev S, Reimand K, Fadeyev V, Peterson P, Uibo R, Ilonen J.

Eur J Endocrinol. 2007 Dec;157(6):757-61.PMID: 18057383 [PubMed - indexed for MEDLINE]Related articlesFree article

Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A.

Nejentsev S, Howson JM, Walker NM, Szeszko J, Field SF, Stevens HE, Reynolds P, Hardy M, King E, Masters J, Hulme J, Maier LM, Smyth D, Bailey R, Cooper JD, Ribas G, Campbell RD, Clayton DG, Todd JA; Wellcome Trust Case Control Consortium.

Nature. 2007 Dec 6;450(7171):887-92. Epub 2007 Nov 14.PMID: 18004301 [PubMed - indexed for MEDLINE]Related articlesFree article

Comprehensive association analysis of the vitamin D pathway genes, VDR, CYP27B1, and CYP24A1, in prostate cancer.

Holick CN, Stanford JL, Kwon EM, Ostrander EA, Nejentsev S, Peters U.

Cancer Epidemiol Biomarkers Prev. 2007 Oct;16(10):1990-9.PMID: 17932346 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of the vitamin D metabolism gene CYP27B1 with type 1 diabetes.

Bailey R, Cooper JD, Zeitels L, Smyth DJ, Yang JH, Walker NM, Hyppönen E, Dunger DB, Ramos-Lopez E, Badenhoop K, Nejentsev S, Todd JA.

Diabetes. 2007 Oct;56(10):2616-21. Epub 2007 Jul 2.PMID: 17606874 [PubMed - indexed for MEDLINE]Related articlesFree article

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.

Todd JA, Walker NM, Cooper JD, Smyth DJ, Downes K, Plagnol V, Bailey R, Nejentsev S, Field SF, Payne F, Lowe CE, Szeszko JS, Hafler JP, Zeitels L, Yang JH, Vella A, Nutland S, Stevens HE, Schuilenburg H, Coleman G, Maisuria M, Meadows W, Smink LJ, Healy B, Burren OS, Lam AA, Ovington NR, Allen J, Adlem E, Leung HT, Wallace C, Howson JM, Guja C, Ionescu-Tîrgovişte C; Genetics of Type 1 Diabetes in Finland, Simmonds MJ, Heward JM, Gough SC; Wellcome Trust Case Control Consortium, Dunger DB, Wicker LS, Clayton DG.

Nat Genet. 2007 Jul;39(7):857-64. Epub 2007 Jun 6.PMID: 17554260 [PubMed - indexed for MEDLINE]Related articlesFree article

Sequencing and association analysis of the type 1 diabetes-linked region on chromosome 10p12-q11.

Nejentsev S, Smink LJ, Smyth D, Bailey R, Lowe CE, Payne F, Masters J, Godfrey L, Lam A, Burren O, Stevens H, Nutland S, Walker NM, Smith A, Twells R, Barratt BJ, Wright C, French L, Chen Y, Deloukas P, Rogers J, Dunham I, Todd JA.

BMC Genet. 2007 May 17;8:24.PMID: 17509149 [PubMed - indexed for MEDLINE]Related articlesFree article

Resequencing and association analysis of the SP110 gene in adult pulmonary tuberculosis.

Szeszko JS, Healy B, Stevens H, Balabanova Y, Drobniewski F, Todd JA, Nejentsev S.

Hum Genet. 2007 Apr;121(2):155-60. Epub 2006 Dec 6.PMID: 17149599 [PubMed - indexed for MEDLINE]Related articles

No evidence for a major effect of two common polymorphisms of the catalase gene in type 1 diabetes susceptibility.

Pask R, Cooper JD, Walker NM, Nutland S, Hutchings J, Dunger DB, Nejentsev S, Todd JA.

Diabetes Metab Res Rev. 2006 Sep-Oct;22(5):356-60.PMID: 16453382 [PubMed - indexed for MEDLINE]Related articles

Genetics of susceptibility to tuberculosis in humans.

Newport MJ, Nejentsev S.

Monaldi Arch Chest Dis. 2004 Apr-Jun;61(2):102-11. Review.PMID: 15510710 [PubMed - indexed for MEDLINE]Related articles

Analysis of the vitamin D receptor gene sequence variants in type 1 diabetes.

Nejentsev S, Cooper JD, Godfrey L, Howson JM, Rance H, Nutland S, Walker NM, Guja C, Ionescu-Tirgovişte C, Savage DA, Undlien DE, Rønningen KS, Tuomilehto-Wolf E, Tuomilehto J, Gillespie KM, Ring SM, Strachan DP, Widmer B, Dunger D, Todd JA.

Diabetes. 2004 Oct;53(10):2709-12.PMID: 15448105 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparative high-resolution analysis of linkage disequilibrium and tag single nucleotide polymorphisms between populations in the vitamin D receptor gene.

Nejentsev S, Godfrey L, Snook H, Rance H, Nutland S, Walker NM, Lam AC, Guja C, Ionescu-Tirgoviste C, Undlien DE, Rønningen KS, Tuomilehto-Wolf E, Tuomilehto J, Newport MJ, Clayton DG, Todd JA.

Hum Mol Genet. 2004 Aug 1;13(15):1633-9. Epub 2004 Jun 2.PMID: 15175274 [PubMed - indexed for MEDLINE]Related articlesFree article

Lack of association of the vitamin D receptor gene with Graves' disease in UK Caucasians.

Collins JE, Heward JM, Nithiyananthan R, Nejentsev S, Todd JA, Franklyn JA, Gough SC.

Clin Endocrinol (Oxf). 2004 May;60(5):618-24.PMID: 15104566 [PubMed - indexed for MEDLINE]Related articles

No association between interferon-gamma receptor-1 gene polymorphism and pulmonary tuberculosis in a Gambian population sample.

Awomoyi AA, Nejentsev S, Richardson A, Hull J, Koch O, Podinovskaia M, Todd JA, McAdam KP, Blackwell JM, Kwiatkowski D, Newport MJ.

Thorax. 2004 Apr;59(4):291-4.PMID: 15047947 [PubMed - indexed for MEDLINE]Related articlesFree article

A linkage study of 12 IDDM susceptibility loci in the Finnish population.

Laine AP, Nejentsev S, Veijola R, Korpinen E, Sjöroos M, Simell O, Knip M, Akerblom HK, Ilonen J.

Diabetes Metab Res Rev. 2004 Mar-Apr;20(2):144-9.PMID: 15037990 [PubMed - indexed for MEDLINE]Related articles

Association of intercellular adhesion molecule-1 gene with type 1 diabetes.

Nejentsev S, Guja C, McCormack R, Cooper J, Howson JM, Nutland S, Rance H, Walker N, Undlien D, Ronningen KS, Tuomilehto-Wolf E, Tuomilehto J, Ionescu-Tirgoviste C, Gale EA, Bingley PJ, Gillespie KM, Savage DA, Carson DJ, Patterson CC, Maxwell AP, Todd JA.

Lancet. 2003 Nov 22;362(9397):1723-4.PMID: 14643123 [PubMed - indexed for MEDLINE]Related articles

Intercellular adhesion molecule-1 K469E polymorphism: study of association with multiple sclerosis.

Nejentsev S, Laaksonen M, Tienari PJ, Fernandez O, Cordell H, Ruutiainen J, Wikström J, Pastinen T, Kuokkanen S, Hillert J, Ilonen J.

Hum Immunol. 2003 Mar;64(3):345-9.PMID: 12590979 [PubMed - indexed for MEDLINE]Related articles

CD86 gene polymorphisms: no association with Type I diabetes among Finnish subjects.

Turpeinen H, Laine AP, Nejentsev S, Sjöroos M, Ilonen J, Simell O, Veijola R, Knip M, Akerblom HK, Knip M.

Diabetologia. 2002 Jul;45(7):1041-2. No abstract available. PMID: 12187923 [PubMed - indexed for MEDLINE]Related articles

HLA haplotype analysis in Finnish patients with rheumatoid arthritis.

Tuokko J, Nejentsev S, Luukkainen R, Toivanen A, Ilonen J.

Arthritis Rheum. 2001 Feb;44(2):315-22.PMID: 11229461 [PubMed - indexed for MEDLINE]Related articlesFree article

Non-class II HLA gene associated with type 1 diabetes maps to the 240-kb region near HLA-B.

Nejentsev S, Gombos Z, Laine AP, Veijola R, Knip M, Simell O, Vaarala O, Akerblom HK, Ilonen J.

Diabetes. 2000 Dec;49(12):2217-21.PMID: 11118029 [PubMed - indexed for MEDLINE]Related articlesFree article

Intercellular adhesion molecule-1 (ICAM-1) K469E polymorphism: no association with type 1 diabetes among Finns.

Nejentsev S, Laine AP, Simell O, Ilonen J.

Tissue Antigens. 2000 Jun;55(6):568-70.PMID: 10902613 [PubMed - indexed for MEDLINE]Related articles

Population-based genetic screening for the estimation of Type 1 diabetes mellitus risk in Finland: selective genotyping of markers in the HLA-DQB1, HLA-DQA1 and HLA-DRB1 loci.

Nejentsev S, Sjöroos M, Soukka T, Knip M, Simell O, Lövgren T, Ilonen J.

Diabet Med. 1999 Dec;16(12):985-92.PMID: 10656226 [PubMed - indexed for MEDLINE]Related articles

Distribution of insulin-dependent diabetes mellitus (IDDM)-related HLA alleles correlates with the difference in IDDM incidence in four populations of the Eastern Baltic region.

Nejentsev S, Koskinen S, Sjöroos M, Reijonen H, Schwartz EI, Kovalchuk L, Sochnev A, Adojaan B, Podar T, Knip M, Simell O, Koskenvuo M, Akerblom HK, Ilonen J.

Tissue Antigens. 1998 Nov;52(5):473-7.PMID: 9864037 [PubMed - indexed for MEDLINE]Related articles

HLA-DR4 subtype and -B alleles in DQB1*0302-positive haplotypes associated with IDDM. The Childhood Diabetes in Finland Study Group.

Reijonen H, Nejentsev S, Tuokko J, Koskinen S, Tuomilehto-Wolf E, Akerblom HK, Ilonen J.

Eur J Immunogenet. 1997 Oct;24(5):357-63.PMID: 9442803 [PubMed - indexed for MEDLINE]Related articles

The effect of HLA-B allele on the IDDM risk defined by DRB1*04 subtypes and DQB1*0302.

Nejentsev S, Reijonen H, Adojaan B, Kovalchuk L, Sochnevs A, Schwartz EI, Akerblom HK, Ilonen J.

Diabetes. 1997 Nov;46(11):1888-92.PMID: 9356041 [PubMed - indexed for MEDLINE]Related articles

HLA-DQB1*0304-DRB1*0408 haplotype associated with insulin-dependent diabetes mellitus in populations in the eastern Baltic region.

Ilonen J, Koskinen S, Nejentsev S, Sjöroos M, Knip M, Schwartz EI, Adojaan B, Kovalchuk L, Sochnevs A.

Tissue Antigens. 1997 May;49(5):532-4.PMID: 9174152 [PubMed - indexed for MEDLINE]Related articles