PubMed

A novel synthetic androgen receptor ligand, S42, works as a selective androgen receptor modulator and possesses metabolic effects with little impact on the prostate.

Min L, Yanase T, Tanaka T, Fan W, Nomura M, Kawate H, Okabe T, Takayanagi R, Nawata H.

Endocrinology. 2009 Dec;150(12):5606-16. Epub 2009 Oct 23.PMID: 19854864 [PubMed - in process]Related articles

Impact of metabolic syndrome on the progression of Intima-Media Thickening in Japanese--a follow-up study.

Matoba Y, Inoguchi T, Suzuki S, Nasu S, Hashimoto T, Yanase T, Nawata H, Takayanagi R.

Diabetes Res Clin Pract. 2009 Dec;86(3):e50-3. Epub 2009 Oct 8.PMID: 19818522 [PubMed - in process]Related articles

Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.

Takeuchi F, Serizawa M, Yamamoto K, Fujisawa T, Nakashima E, Ohnaka K, Ikegami H, Sugiyama T, Katsuya T, Miyagishi M, Nakashima N, Nawata H, Nakamura J, Kono S, Takayanagi R, Kato N.

Diabetes. 2009 Jul;58(7):1690-9. Epub 2009 Apr 28.PMID: 19401414 [PubMed - indexed for MEDLINE]Related articlesFree article

High prevalence of peripheral arterial disease diagnosed by low ankle-brachial index in Japanese patients with diabetes: the Kyushu Prevention Study for Atherosclerosis.

Maeda Y, Inoguchi T, Tsubouchi H, Sawada F, Sasaki S, Fujii M, Saito R, Yanase T, Shimabukuro M, Nawata H, Takayanagi R.

Diabetes Res Clin Pract. 2008 Dec;82(3):378-82. Epub 2008 Oct 19.PMID: 18930561 [PubMed - indexed for MEDLINE]Related articles

Functional potentiation of leptin-signal transducer and activator of transcription 3 signaling by the androgen receptor.

Fan W, Yanase T, Nishi Y, Chiba S, Okabe T, Nomura M, Yoshimatsu H, Kato S, Takayanagi R, Nawata H.

Endocrinology. 2008 Dec;149(12):6028-36. Epub 2008 Aug 14.PMID: 18703637 [PubMed - indexed for MEDLINE]Related articles

Adipose tissue-derived and bone marrow-derived mesenchymal cells develop into different lineage of steroidogenic cells by forced expression of steroidogenic factor 1.

Gondo S, Okabe T, Tanaka T, Morinaga H, Nomura M, Takayanagi R, Nawata H, Yanase T.

Endocrinology. 2008 Sep;149(9):4717-25. Epub 2008 Jun 19.PMID: 18566117 [PubMed - indexed for MEDLINE]Related articlesFree article

Androgens and metabolic syndrome: lessons from androgen receptor knock out (ARKO) mice.

Yanase T, Fan W, Kyoya K, Min L, Takayanagi R, Kato S, Nawata H.

J Steroid Biochem Mol Biol. 2008 Apr;109(3-5):254-7. Epub 2008 Mar 13.PMID: 18472261 [PubMed - indexed for MEDLINE]Related articles

Methylation of a conserved intronic CpG island of mouse SF-1 is associated with cell-specific expression of SF-1 in a culture system but not with tissue-specific expression.

Shirohzu H, Okabe T, Gondo S, Tanaka T, Ohe K, Morinaga H, Kawate H, Nomura M, Takayanagi R, Nawata H, Yanase T.

Biochem Biophys Res Commun. 2008 May 9;369(3):862-7. Epub 2008 Mar 4.PMID: 18325326 [PubMed - indexed for MEDLINE]Related articles

Blocking of monocyte chemoattractant protein-1 (MCP-1) activity attenuates the severity of acute pancreatitis in rats.

Ishibashi T, Zhao H, Kawabe K, Oono T, Egashira K, Suzuki K, Nawata H, Takayanagi R, Ito T.

J Gastroenterol. 2008;43(1):79-85. Epub 2008 Feb 24.PMID: 18297440 [PubMed - indexed for MEDLINE]Related articles

[Steroid receptor superfamily and its mechanism of action]

Nawata H, Yanase T, Okabe T, Nomura M.

Nippon Rinsho. 2008 Jan;66(1):9-15. Review. Japanese. PMID: 18186252 [PubMed - indexed for MEDLINE]Related articles

Frequent microsatellite instability in non-Hodgkin lymphomas irresponsive to chemotherapy.

Miyashita K, Fujii K, Yamada Y, Hattori H, Taguchi K, Yamanaka T, Yoshida MA, Okamura J, Oda S, Muta K, Nawata H, Takayanagi R, Uike N.

Leuk Res. 2008 Aug;32(8):1183-95. Epub 2008 Jan 4.PMID: 18177936 [PubMed - indexed for MEDLINE]Related articles

Optimal cut points of waist circumference for the clinical diagnosis of metabolic syndrome in the Japanese population.

Matoba Y, Inoguchi T, Nasu S, Suzuki S, Yanase T, Nawata H, Takayanagi R.

Diabetes Care. 2008 Mar;31(3):590-2. Epub 2007 Dec 10. No abstract available. PMID: 18071008 [PubMed - indexed for MEDLINE]Related articlesFree article

Steroidogenic factor 1/adrenal 4 binding protein transforms human bone marrow mesenchymal cells into steroidogenic cells.

Tanaka T, Gondo S, Okabe T, Ohe K, Shirohzu H, Morinaga H, Nomura M, Tani K, Takayanagi R, Nawata H, Yanase T.

J Mol Endocrinol. 2007 Nov;39(5):343-50.PMID: 17975261 [PubMed - indexed for MEDLINE]Related articlesFree article

Glutathione S-transferase theta 1 expressed in granulosa cells as a biomarker for oocyte quality in age-related infertility.

Ito M, Muraki M, Takahashi Y, Imai M, Tsukui T, Yamakawa N, Nakagawa K, Ohgi S, Horikawa T, Iwasaki W, Iida A, Nishi Y, Yanase T, Nawata H, Miyado K, Kono T, Hosoi Y, Saito H.

Fertil Steril. 2008 Oct;90(4):1026-35. Epub 2007 Oct 24.PMID: 17919612 [PubMed - indexed for MEDLINE]Related articles

A Japanese model of disease management.

Nakashima N, Kobayashi K, Inoguchi T, Nishida D, Tanaka N, Nakazono H, Hoshino A, Soejima H, Takayanagi R, Nawata H.

Stud Health Technol Inform. 2007;129(Pt 2):1174-8.PMID: 17911900 [PubMed - indexed for MEDLINE]Related articles

Genetic interactions between activin type IIB receptor and Smad2 genes in asymmetrical patterning of the thoracic organs and the development of pancreas islets.

Goto Y, Nomura M, Tanaka K, Kondo A, Morinaga H, Okabe T, Yanase T, Nawata H, Takayanagi R, Li E.

Dev Dyn. 2007 Oct;236(10):2865-74.PMID: 17849440 [PubMed - indexed for MEDLINE]Related articlesFree article

Atrazine-induced aromatase expression is SF-1 dependent: implications for endocrine disruption in wildlife and reproductive cancers in humans.

Fan W, Yanase T, Morinaga H, Gondo S, Okabe T, Nomura M, Komatsu T, Morohashi K, Hayes TB, Takayanagi R, Nawata H.

Environ Health Perspect. 2007 May;115(5):720-7. Epub 2007 Feb 5.PMID: 17520059 [PubMed - indexed for MEDLINE]Related articlesFree article

The pituitary function of androgen receptor constitutes a glucocorticoid production circuit.

Miyamoto J, Matsumoto T, Shiina H, Inoue K, Takada I, Ito S, Itoh J, Minematsu T, Sato T, Yanase T, Nawata H, Osamura YR, Kato S.

Mol Cell Biol. 2007 Jul;27(13):4807-14. Epub 2007 Apr 30.PMID: 17470551 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification and synergism of cis-acting elements essential for basal promoter activity of the human type 1 angiotensin II receptor gene in PLC-PRF-5 cells.

Shimoda S, Ohnaka K, Sakai Y, Nawata H, Takayanagi R.

Endocr J. 2007 Jun;54(3):413-24. Epub 2007 Apr 20.PMID: 17446655 [PubMed - indexed for MEDLINE]Related articlesFree article

Fertile females with nonalcoholic fatty liver disease (NAFLD) have higher levels of ALT than postmenopausal females: implications for the influence of fertility on NAFLD.

Kotoh K, Nakamuta M, Fukushima M, Morizono S, Enjoji M, Nawata H.

Hepatogastroenterology. 2007 Jan-Feb;54(73):224-8.PMID: 17419265 [PubMed - indexed for MEDLINE]Related articles

Prospective randomized trial of transnasal versus peroral endoscopy using an ultrathin videoendoscope in unsedated patients.

Murata A, Akahoshi K, Sumida Y, Yamamoto H, Nakamura K, Nawata H.

J Gastroenterol Hepatol. 2007 Apr;22(4):482-5.PMID: 17376037 [PubMed - indexed for MEDLINE]Related articles

Herbicide atrazine activates SF-1 by direct affinity and concomitant co-activators recruitments to induce aromatase expression via promoter II.

Fan W, Yanase T, Morinaga H, Gondo S, Okabe T, Nomura M, Hayes TB, Takayanagi R, Nawata H.

Biochem Biophys Res Commun. 2007 Apr 20;355(4):1012-8. Epub 2007 Feb 22.PMID: 17331471 [PubMed - indexed for MEDLINE]Related articles

Insulin-like growth factor 1/insulin signaling activates androgen signaling through direct interactions of Foxo1 with androgen receptor.

Fan W, Yanase T, Morinaga H, Okabe T, Nomura M, Daitoku H, Fukamizu A, Kato S, Takayanagi R, Nawata H.

J Biol Chem. 2007 Mar 9;282(10):7329-38. Epub 2007 Jan 2.PMID: 17202144 [PubMed - indexed for MEDLINE]Related articlesFree article

Changes in serum sex hormone profiles after short-term low-dose administration of dehydroepiandrosterone (DHEA) to young and elderly persons.

Yamada Y, Sekihara H, Omura M, Yanase T, Takayanagi R, Mune T, Yasuda K, Ishizuka T, Ueshiba H, Miyachi Y, Iwasaki T, Nakajima A, Nawata H.

Endocr J. 2007 Feb;54(1):153-62. Epub 2006 Dec 21.PMID: 17185878 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluation of a new carotid intima-media thickness measurement by B-mode ultrasonography using an innovative measurement software, intimascope.

Yanase T, Nasu S, Mukuta Y, Shimizu Y, Nishihara T, Okabe T, Nomura M, Inoguchi T, Nawata H.

Am J Hypertens. 2006 Dec;19(12):1206-12.PMID: 17161764 [PubMed - indexed for MEDLINE]Related articles

Successful treatment of advanced-stage autoimmune pancreatitis-related sclerosing cholangitis.

Kawabe K, Ito T, Arita Y, Nakamuta M, Nawata H, Takayanagi R.

Pancreas. 2006 Nov;33(4):434-7. No abstract available. PMID: 17079953 [PubMed - indexed for MEDLINE]Related articles

Modification of glucocorticoid sensitivity by MAP kinase signaling pathways in glucocorticoid-induced T-cell apoptosis.

Tanaka T, Okabe T, Gondo S, Fukuda M, Yamamoto M, Umemura T, Tani K, Nomura M, Goto K, Yanase T, Nawata H.

Exp Hematol. 2006 Nov;34(11):1542-52.PMID: 17046574 [PubMed - indexed for MEDLINE]Related articles

Therapeutic angiogenesis by ex vivo expanded erythroid progenitor cells.

Sasaki S, Inoguchi T, Muta K, Abe Y, Zhang M, Hiasa K, Egashira K, Sonoda N, Kobayashi K, Takayanagi R, Nawata H.

Am J Physiol Heart Circ Physiol. 2007 Jan;292(1):H657-65. Epub 2006 Sep 22.PMID: 16997894 [PubMed - indexed for MEDLINE]Related articlesFree article

Sustained contraction and loss of NO production in TGFbeta1-treated endothelial cells.

Watanabe M, Oike M, Ohta Y, Nawata H, Ito Y.

Br J Pharmacol. 2006 Oct;149(4):355-64. Epub 2006 Sep 11.PMID: 16967050 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficacy and tolerability of once-weekly administration of 17.5 mg risedronate in Japanese patients with involutional osteoporosis: a comparison with 2.5-mg once-daily dosage regimen.

Kishimoto H, Fukunaga M, Kushida K, Shiraki M, Itabashi A, Nawata H, Nakamura T, Ohta H, Takaoka K, Ohashi Y; Risedronate Phase III Research Group.

J Bone Miner Metab. 2006;24(5):405-13.PMID: 16937274 [PubMed - indexed for MEDLINE]Related articles

Pivotal role of Notch signaling in regulation of erythroid maturation and proliferation.

Tachikawa Y, Matsushima T, Abe Y, Sakano S, Yamamoto M, Nishimura J, Nawata H, Takayanagi R, Muta K.

Eur J Haematol. 2006 Oct;77(4):273-81. Epub 2006 Aug 23.PMID: 16930143 [PubMed - indexed for MEDLINE]Related articles

Nuclear compartmentalization of N-CoR and its interactions with steroid receptors.

Wu Y, Kawate H, Ohnaka K, Nawata H, Takayanagi R.

Mol Cell Biol. 2006 Sep;26(17):6633-55.PMID: 16914745 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreatic pseudocyst after acute organophosphate poisoning.

Kawabe K, Ito T, Arita Y, Sadamoto Y, Harada N, Yamaguchi K, Tanaka M, Nakano I, Nawata H, Takayanagi R.

Fukuoka Igaku Zasshi. 2006 Apr;97(4):123-9.PMID: 16850858 [PubMed - indexed for MEDLINE]Related articles

Differentiation and regeneration of adrenal tissues: An initial step toward regeneration therapy for steroid insufficiency.

Yanase T, Gondo S, Okabe T, Tanaka T, Shirohzu H, Fan W, Oba K, Morinaga H, Nomura M, Ohe K, Nawata H.

Endocr J. 2006 Aug;53(4):449-59. Epub 2006 Jun 27. Review.PMID: 16807499 [PubMed - indexed for MEDLINE]Related articlesFree article

Statin attenuates high glucose-induced and angiotensin II-induced MAP kinase activity through inhibition of NAD(P)H oxidase activity in cultured mesangial cells.

Yu HY, Inoguchi T, Nakayama M, Tsubouchi H, Sato N, Sonoda N, Sasaki S, Kobayashi K, Nawata H.

Med Chem. 2005 Sep;1(5):461-6.PMID: 16787330 [PubMed - indexed for MEDLINE]Related articles

Endoscopic band ligation therapy for upper gastrointestinal bleeding related to Mallory-Weiss syndrome.

Higuchi N, Akahoshi K, Sumida Y, Kubokawa M, Motomura Y, Kimura M, Matsumoto M, Nakamura K, Nawata H.

Surg Endosc. 2006 Sep;20(9):1431-4. Epub 2006 May 15.PMID: 16703428 [PubMed - indexed for MEDLINE]Related articles

An inverse correlation of human peripheral blood regulatory T cell frequency with the disease activity of ulcerative colitis.

Takahashi M, Nakamura K, Honda K, Kitamura Y, Mizutani T, Araki Y, Kabemura T, Chijiiwa Y, Harada N, Nawata H.

Dig Dis Sci. 2006 Apr;51(4):677-86.PMID: 16614988 [PubMed - indexed for MEDLINE]Related articles

The Gly146Ala variation in human SF-1 gene: its association with insulin resistance and type 2 diabetes in Chinese.

Liu W, Liu M, Fan W, Nawata H, Yanase T.

Diabetes Res Clin Pract. 2006 Sep;73(3):322-8. Epub 2006 Mar 27.PMID: 16564598 [PubMed - indexed for MEDLINE]Related articles

Adult case of an omphalomesenteric cyst resected by laparoscopic-assisted surgery.

Sawada F, Yoshimura R, Ito K, Nakamura K, Nawata H, Mizumoto K, Shimizu S, Inoue T, Yao T, Tsuneyoshi M, Kondo A, Harada N.

World J Gastroenterol. 2006 Feb 7;12(5):825-7.PMID: 16521206 [PubMed - indexed for MEDLINE]Related articlesFree article

[Adrenal androgen and bone metabolism]

Goto K, Yanase T, Takayanagi R, Nawata H.

Clin Calcium. 2006 Mar;16(3):429-35. Review. Japanese. PMID: 16508124 [PubMed - indexed for MEDLINE]Related articles

[Second nonmyeloablative allogeneic peripheral blood stem cell transplantation with more immunosuppressive conditioning regimen for the late graft failure of the patient with acute myeloid leukemia]

Tachikawa Y, Abe Y, Choi I, Ohtsuka R, Nagasawa E, Shibata K, Nishimura J, Nawata H, Muta K.

Fukuoka Igaku Zasshi. 2005 Nov;96(11):378-82. Japanese. PMID: 16502857 [PubMed - indexed for MEDLINE]Related articles

Suppressor of cytokine signaling-1 regulates inflammatory bowel disease in which both IFNgamma and IL-4 are involved.

Chinen T, Kobayashi T, Ogata H, Takaesu G, Takaki H, Hashimoto M, Yagita H, Nawata H, Yoshimura A.

Gastroenterology. 2006 Feb;130(2):373-88.PMID: 16472593 [PubMed - indexed for MEDLINE]Related articles

Adipose differentiation related protein induces lipid accumulation and lipid droplet formation in hepatic stellate cells.

Fukushima M, Enjoji M, Kohjima M, Sugimoto R, Ohta S, Kotoh K, Kuniyoshi M, Kobayashi K, Imamura M, Inoguchi T, Nakamuta M, Nawata H.

In Vitro Cell Dev Biol Anim. 2005 Nov-Dec;41(10):321-4.PMID: 16448220 [PubMed - indexed for MEDLINE]Related articles

[Genetic testing and gene-based testing for endocrine disorders]

Yanase T, Nawata H.

Nippon Rinsho. 2005 Dec;63 Suppl 12:207-11. Review. Japanese. No abstract available. PMID: 16416795 [PubMed - indexed for MEDLINE]Related articles

Identification of the functional domains of ANT-1, a novel coactivator of the androgen receptor.

Fan S, Goto K, Chen G, Morinaga H, Nomura M, Okabe T, Nawata H, Yanase T.

Biochem Biophys Res Commun. 2006 Mar 3;341(1):192-201. Epub 2006 Jan 9.PMID: 16414017 [PubMed - indexed for MEDLINE]Related articles

[Sex steroids and metabolic syndrome]

Yanase T, Fan W, Nawata H.

Nippon Ronen Igakkai Zasshi. 2005 Nov;42(6):633-5. Japanese. No abstract available. PMID: 16408501 [PubMed - indexed for MEDLINE]Related articles

INHA promoter polymorphisms are associated with premature ovarian failure.

Harris SE, Chand AL, Winship IM, Gersak K, Nishi Y, Yanase T, Nawata H, Shelling AN.

Mol Hum Reprod. 2005 Nov;11(11):779-84. Epub 2006 Jan 3.PMID: 16390856 [PubMed - indexed for MEDLINE]Related articlesFree article

T helper 1-inducing property of IL-27/WSX-1 signaling is required for the induction of experimental colitis.

Honda K, Nakamura K, Matsui N, Takahashi M, Kitamura Y, Mizutani T, Harada N, Nawata H, Hamano S, Yoshida H.

Inflamm Bowel Dis. 2005 Dec;11(12):1044-52.PMID: 16306766 [PubMed - indexed for MEDLINE]Related articles

Anti-monocyte chemoattractant protein 1 gene therapy attenuates experimental chronic pancreatitis induced by dibutyltin dichloride in rats.

Zhao HF, Ito T, Gibo J, Kawabe K, Oono T, Kaku T, Arita Y, Zhao QW, Usui M, Egashira K, Nawata H.

Gut. 2005 Dec;54(12):1759-67.PMID: 16284287 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of adipose differentiation-related protein (ADRP) is conjointly regulated by PU.1 and AP-1 in macrophages.

Wei P, Taniguchi S, Sakai Y, Imamura M, Inoguchi T, Nawata H, Oda S, Nakabeppu Y, Nishimura J, Ikuyama S.

J Biochem. 2005 Oct;138(4):399-412.PMID: 16272134 [PubMed - indexed for MEDLINE]Related articles