PubMed

Adipose Tissue-Derived Stem Cells Inhibit Neointimal Formation in a Paracrine Fashion in Rat Femoral Artery.

Takahashi M, Suzuki E, Oba S, Nishimatsu H, Kimura K, Nagano T, Nagai R, Hirata Y.

Am J Physiol Heart Circ Physiol. 2009 Nov 25. [Epub ahead of print]PMID: 19940081 [PubMed - as supplied by publisher]

AGE-Modified Collagens I and III Induce Keratinocyte Terminal Differentiation through AGE Receptor CD36: Epidermal-Dermal Interaction in Acquired Perforating Dermatosis.

Fujimoto E, Kobayashi T, Fujimoto N, Akiyama M, Tajima S, Nagai R.

J Invest Dermatol. 2009 Oct 29. [Epub ahead of print]PMID: 19865095 [PubMed - as supplied by publisher]Related articles

Glycation of a food allergen by the Maillard reaction enhances its T-cell immunogenicity: Role of macrophage scavenger receptor class A type I and II.

Ilchmann A, Burgdorf S, Scheurer S, Waibler Z, Nagai R, Wellner A, Yamamoto Y, Yamamoto H, Henle T, Kurts C, Kalinke U, Vieths S, Toda M.

J Allergy Clin Immunol. 2009 Oct 26. [Epub ahead of print]PMID: 19864011 [PubMed - as supplied by publisher]Related articles

Regulation of transforming growth factor-{beta}-dependent cyclooxygenase-2 expression in fibroblasts.

Matsumura T, Suzuki T, Aizawa K, Sawaki D, Munemasa Y, Ishida J, Nagai R.

J Biol Chem. 2009 Oct 16. [Epub ahead of print]PMID: 19837676 [PubMed - as supplied by publisher]Related articlesFree article

Syntrophin-2 is required for eye development in Drosophila.

Nagai R, Hashimoto R, Tanaka Y, Taguchi O, Sato M, Matsukage A, Yamaguchi M.

Exp Cell Res. 2009 Oct 23. [Epub ahead of print]PMID: 19836389 [PubMed - as supplied by publisher]Related articles

Cardiovascular event rates in patients with cerebrovascular disease and atherothrombosis at other vascular locations: results from 1-year outcomes in the Japanese REACH Registry.

Uchiyama S, Goto S, Matsumoto M, Nagai R, Origasa H, Yamazaki T, Shigematsu H, Shimada K, Yamada N, Bhatt DL, Steg PG, Ikeda Y; REduction of Atherothrombosis for Continued Health Registry Investigators.

J Neurol Sci. 2009 Dec 15;287(1-2):45-51. Epub 2009 Oct 7.PMID: 19815240 [PubMed - in process]Related articles

Adipose tissue inflammation in obesity and metabolic syndrome.

Nishimura S, Manabe I, Nagai R.

Discov Med. 2009 Aug;8(41):55-60.PMID: 19788868 [PubMed - in process]Related articles

Periadventitial adipose tissue plays a critical role in vascular remodeling.

Takaoka M, Nagata D, Kihara S, Shimomura I, Kimura Y, Tabata Y, Saito Y, Nagai R, Sata M.

Circ Res. 2009 Oct 23;105(9):906-11. Epub 2009 Sep 17.PMID: 19762682 [PubMed - indexed for MEDLINE]Related articles

Effect of reactive-aldehydes on the modification and dysfunction of human serum albumin.

Mera K, Takeo K, Izumi M, Maruyama T, Nagai R, Otagiri M.

J Pharm Sci. 2009 Sep 16. [Epub ahead of print]PMID: 19760671 [PubMed - as supplied by publisher]Related articles

Ablation of neutral cholesterol ester hydrolase 1 accelerates atherosclerosis.

Sekiya M, Osuga J, Nagashima S, Ohshiro T, Igarashi M, Okazaki H, Takahashi M, Tazoe F, Wada T, Ohta K, Takanashi M, Kumagai M, Nishi M, Takase S, Yahagi N, Yagyu H, Ohashi K, Nagai R, Kadowaki T, Furukawa Y, Ishibashi S.

Cell Metab. 2009 Sep;10(3):219-28.PMID: 19723498 [PubMed - in process]Related articles

Astragalosides isolated from the root of astragalus radix inhibit the formation of advanced glycation end products.

Motomura K, Fujiwara Y, Kiyota N, Tsurushima K, Takeya M, Nohara T, Nagai R, Ikeda T.

J Agric Food Chem. 2009 Sep 9;57(17):7666-72.PMID: 19681610 [PubMed - in process]Related articles

Detecting occult coronary artery disease followed by early coronary artery bypass surgery in patients with diabetic retinopathy: Report from a diabetic retinocoronary clinic.

Ohno T, Kinoshita O, Fujita H, Kato S, Hirose A, Sigeeda T, Otomo K, Ando J, Kadowaki T, Araie M, Nagai R, Takamoto S.

J Thorac Cardiovasc Surg. 2009 Jun 16. [Epub ahead of print]PMID: 19660392 [PubMed - as supplied by publisher]Related articles

A nanoparticle system specifically designed to deliver short interfering RNA inhibits tumor growth in vivo.

Yagi N, Manabe I, Tottori T, Ishihara A, Ogata F, Kim JH, Nishimura S, Fujiu K, Oishi Y, Itaka K, Kato Y, Yamauchi M, Nagai R.

Cancer Res. 2009 Aug 15;69(16):6531-8. Epub 2009 Aug 4.PMID: 19654315 [PubMed - indexed for MEDLINE]Related articles

Tea polyphenols regulate key mediators on inflammatory cardiovascular diseases.

Suzuki J, Isobe M, Morishita R, Nagai R.

Mediators Inflamm. 2009;2009:494928. Epub 2009 Jul 19. Review.PMID: 19636434 [PubMed - indexed for MEDLINE]Related articlesFree article

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity.

Nishimura S, Manabe I, Nagasaki M, Eto K, Yamashita H, Ohsugi M, Otsu M, Hara K, Ueki K, Sugiura S, Yoshimura K, Kadowaki T, Nagai R.

Nat Med. 2009 Aug;15(8):914-20. Epub 2009 Jul 26.PMID: 19633658 [PubMed - indexed for MEDLINE]Related articles

Hormone-sensitive lipase deficiency suppresses insulin secretion from pancreatic islets of Lep ob/ob mice.

Sekiya M, Yahagi N, Tamura Y, Okazaki H, Igarashi M, Ohta K, Takanashi M, Kumagai M, Takase S, Nishi M, Takeuchi Y, Izumida Y, Kubota M, Ohashi K, Iizuka Y, Yagyu H, Gotoda T, Nagai R, Shimano H, Yamada N, Kadowaki T, Ishibashi S, Osuga J.

Biochem Biophys Res Commun. 2009 Sep 25;387(3):511-5. Epub 2009 Jul 18.PMID: 19619509 [PubMed - indexed for MEDLINE]Related articles

Infective endocarditis by bartonellaquintana masquerading as antineutrophil cytoplasmic antibody-associated small vessel vasculitis.

Sugiyama H, Sahara M, Imai Y, Ono M, Okamoto K, Kikuchi K, Nagai R.

Cardiology. 2009;114(3):208-11. Epub 2009 Jul 15.PMID: 19602882 [PubMed - in process]Related articles

Targeting of neutral cholesterol ester hydrolase to the endoplasmic reticulum via its N-terminal sequence.

Igarashi M, Osuga JI, Isshiki M, Sekiya M, Okazaki H, Takase S, Takanashi M, Ohta K, Kumagai M, Nishi M, Fujita T, Nagai R, Kadowaki T, Ishibashi S.

J Lipid Res. 2009 Jul 10. [Epub ahead of print]PMID: 19592704 [PubMed - as supplied by publisher]Related articlesFree article

Succination of thiol groups in adipose tissue proteins in diabetes: succination inhibits polymerization and secretion of adiponectin.

Frizzell N, Rajesh M, Jepson MJ, Nagai R, Carson JA, Thorpe SR, Baynes JW.

J Biol Chem. 2009 Sep 18;284(38):25772-81. Epub 2009 Jul 10.PMID: 19592500 [PubMed - indexed for MEDLINE]Related articles

A novel Drosophila Girdin-like protein is involved in Akt pathway control of cell size.

Puseenam A, Yoshioka Y, Nagai R, Hashimoto R, Suyari O, Itoh M, Enomoto A, Takahashi M, Yamaguchi M.

Exp Cell Res. 2009 Nov 15;315(19):3370-80. Epub 2009 Jun 26.PMID: 19560458 [PubMed - in process]Related articles

Local delivery of synthetic prostacycline agonist augments collateral growth and improves cardiac function in a swine chronic cardiac ischemia model.

Iwata H, Nakamura K, Sumi M, Ninomiya M, Sakai Y, Hirata Y, Akaike M, Igarashi T, Takamoto S, Nagai R, Sata M.

Life Sci. 2009 Jul 31;85(5-6):255-61. Epub 2009 Jun 13.PMID: 19527738 [PubMed - indexed for MEDLINE]Related articles

[Genomic research in hypertension and cardiovascular diseases]

Morita H, Nagai R.

Nippon Rinsho. 2009 Jun;67(6):1095-102. Japanese. PMID: 19507499 [PubMed - indexed for MEDLINE]Related articles

Announcement of retraction.

Nagai R.

Int Heart J. 2009 May;50(3):405. No abstract available. PMID: 19506343 [PubMed - indexed for MEDLINE]Related articlesFree article

The mechanism of anti-inflammatory effects of prostaglandin E2 receptor 4 activation in murine cardiac transplantation.

Ogawa M, Suzuki J, Kosuge H, Takayama K, Nagai R, Isobe M.

Transplantation. 2009 Jun 15;87(11):1645-53.PMID: 19502955 [PubMed - indexed for MEDLINE]Related articles

Immunohistochemical detection of advanced glycation end products in human bladder with specific monoclonal antibody.

Matsumoto K, Fujiwara Y, Nagai R, Yoshida M.

Int J Urol. 2009 Apr;16(4):402-5; discussion 405-6.PMID: 19425220 [PubMed - indexed for MEDLINE]Related articles

Association between changes in obesity parameters and incidence of chronic kidney disease in Japanese individuals.

Ishizaka Y, Ishizaka N, Tani M, Toda A, Toda E, Koike K, Nagai R, Yamakado M.

Kidney Blood Press Res. 2009;32(2):141-9. Epub 2009 Apr 30.PMID: 19407460 [PubMed - in process]Related articles

Fluvastatin accelerates re-endothelialization impaired by local sirolimus treatment.

Fukuda D, Enomoto S, Shirakawa I, Nagai R, Sata M.

Eur J Pharmacol. 2009 Jun 10;612(1-3):87-92. Epub 2009 Apr 14.PMID: 19371739 [PubMed - indexed for MEDLINE]Related articles

Molecular dynamism of Fe-S cluster biosynthesis implicated by the structure of the SufC(2)-SufD(2) complex.

Wada K, Sumi N, Nagai R, Iwasaki K, Sato T, Suzuki K, Hasegawa Y, Kitaoka S, Minami Y, Outten FW, Takahashi Y, Fukuyama K.

J Mol Biol. 2009 Mar 20;387(1):245-58. Epub 2009 Jan 31.PMID: 19361433 [PubMed - indexed for MEDLINE]Related articles

A critical role of COX-2 in the progression of neointimal formation after wire injury in mice.

Ogawa M, Suzuki J, Hirata Y, Nagai R, Isobe M.

Expert Opin Ther Targets. 2009 May;13(5):505-11.PMID: 19344227 [PubMed - indexed for MEDLINE]Related articles

Elevated serum uric acid is an independent predictor for cardiovascular events in patients with severe coronary artery stenosis: subanalysis of the Japanese Coronary Artery Disease (JCAD) Study.

Okura T, Higaki J, Kurata M, Irita J, Miyoshi K, Yamazaki T, Hayashi D, Kohro T, Nagai R; Japanese Coronary Artery Disease Study Investigators.

Circ J. 2009 May;73(5):885-91. Epub 2009 Mar 31.PMID: 19336924 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of renin-angiotensin system attenuates periadventitial inflammation and reduces atherosclerotic lesion formation.

Fukuda D, Enomoto S, Nagai R, Sata M.

Biomed Pharmacother. 2009 Mar 10. [Epub ahead of print]PMID: 19304450 [PubMed - as supplied by publisher]Related articles

Smoking exposure, 17q21 variants, and early-onset asthma.

Morita H, Nagai R.

N Engl J Med. 2009 Mar 19;360(12):1255; author reply 1255-6. No abstract available. PMID: 19297581 [PubMed - indexed for MEDLINE]Related articles

Gender differences in patients with coronary artery disease in Japan: the Japanese Coronary Artery Disease Study (the JCAD study).

Kambara H, Yamazaki T, Hayashi D, Kohro T, Okada Y, Nagai R; Japanese Coronary Artery Disease Study Investigators.

Circ J. 2009 May;73(5):912-7. Epub 2009 Mar 11.PMID: 19276612 [PubMed - indexed for MEDLINE]Related articlesFree article

A new constitutively active mutant of AMP-activated protein kinase inhibits anoxia-induced apoptosis of vascular endothelial cell.

Nagata D, Kiyosue A, Takahashi M, Satonaka H, Tanaka K, Sata M, Nagano T, Nagai R, Hirata Y.

Hypertens Res. 2009 Feb;32(2):133-9. Epub 2009 Jan 23.PMID: 19262472 [PubMed - in process]Related articles

Genetically elevated C-reactive protein and vascular disease.

Morita H, Nagai R.

N Engl J Med. 2009 Feb 26;360(9):934; author reply 934-5. No abstract available. PMID: 19256031 [PubMed - indexed for MEDLINE]Related articles

Adiponectin suppresses hepatic SREBP1c expression in an AdipoR1/LKB1/AMPK dependent pathway.

Awazawa M, Ueki K, Inabe K, Yamauchi T, Kaneko K, Okazaki Y, Bardeesy N, Ohnishi S, Nagai R, Kadowaki T.

Biochem Biophys Res Commun. 2009 Apr 24;382(1):51-6. Epub 2009 Feb 28.PMID: 19254698 [PubMed - indexed for MEDLINE]Related articles

Glyoxalase I overexpression ameliorates renal ischemia-reperfusion injury in rats.

Kumagai T, Nangaku M, Kojima I, Nagai R, Ingelfinger JR, Miyata T, Fujita T, Inagi R.

Am J Physiol Renal Physiol. 2009 Apr;296(4):F912-21. Epub 2009 Feb 11.PMID: 19211689 [PubMed - indexed for MEDLINE]Related articles

Kruppel-like factor 5 shows proliferation-specific roles in vascular remodeling, direct stimulation of cell growth, and inhibition of apoptosis.

Suzuki T, Sawaki D, Aizawa K, Munemasa Y, Matsumura T, Ishida J, Nagai R.

J Biol Chem. 2009 Apr 3;284(14):9549-57. Epub 2009 Feb 3.PMID: 19189969 [PubMed - indexed for MEDLINE]Related articles

In early-stage diabetic retinopathy, risk of cardiac events after implantation of sirolimus-eluting stent is higher than after coronary artery bypass surgery.

Masuzawa A, Ohno T, Takamoto S, Motomura N, Ono M, Fujita H, Ando J, Morita T, Hirata Y, Nagai R, Hirose A, Shigeeda T, Kato S, Araie M.

J Cardiol. 2009 Feb;53(1):86-93. Epub 2008 Nov 5.PMID: 19167643 [PubMed - in process]Related articles

Administration of angiotensin II, but not catecholamines, induces accumulation of lipids in the rat heart.

Hongo M, Ishizaka N, Furuta K, Yahagi N, Saito K, Sakurai R, Matsuzaki G, Koike K, Nagai R.

Eur J Pharmacol. 2009 Feb 14;604(1-3):87-92. Epub 2008 Dec 10.PMID: 19109942 [PubMed - indexed for MEDLINE]Related articles

Angptl 4 deficiency improves lipid metabolism, suppresses foam cell formation and protects against atherosclerosis.

Adachi H, Fujiwara Y, Kondo T, Nishikawa T, Ogawa R, Matsumura T, Ishii N, Nagai R, Miyata K, Tabata M, Motoshima H, Furukawa N, Tsuruzoe K, Kawashima J, Takeya M, Yamashita S, Koh GY, Nagy A, Suda T, Oike Y, Araki E.

Biochem Biophys Res Commun. 2009 Feb 20;379(4):806-11. Epub 2008 Dec 16.PMID: 19094966 [PubMed - indexed for MEDLINE]Related articles

Association between metabolic syndrome and carotid atherosclerosis in individuals without diabetes based on the oral glucose tolerance test.

Ishizaka N, Ishizaka Y, Yamakado M, Toda E, Koike K, Nagai R.

Atherosclerosis. 2009 Jun;204(2):619-23. Epub 2008 Oct 30.PMID: 19056083 [PubMed - indexed for MEDLINE]Related articles

Candesartan ameliorates cardiac dysfunction observed in angiotensin-converting enzyme 2-deficient mice.

Nakamura K, Koibuchi N, Nishimatsu H, Higashikuni Y, Hirata Y, Kugiyama K, Nagai R, Sata M.

Hypertens Res. 2008 Oct;31(10):1953-61.PMID: 19015603 [PubMed - indexed for MEDLINE]Related articles

Elevated serum C-reactive protein levels predict cardiovascular events in the Japanese coronary artery disease (JCAD) study.

Shimada K, Fujita M, Tanaka A, Yoshida K, Jisso S, Tanaka H, Yoshikawa J, Kohro T, Hayashi D, Okada Y, Yamazaki T, Nagai R; JCAD Investigators.

Circ J. 2009 Jan;73(1):78-85. Epub 2008 Nov 17.PMID: 19015587 [PubMed - indexed for MEDLINE]Related articlesFree article

Rimonabant ameliorates insulin resistance via both adiponectin-dependent and adiponectin-independent pathways.

Watanabe T, Kubota N, Ohsugi M, Kubota T, Takamoto I, Iwabu M, Awazawa M, Katsuyama H, Hasegawa C, Tokuyama K, Moroi M, Sugi K, Yamauchi T, Noda T, Nagai R, Terauchi Y, Tobe K, Ueki K, Kadowaki T.

J Biol Chem. 2009 Jan 16;284(3):1803-12. Epub 2008 Nov 13.PMID: 19008231 [PubMed - indexed for MEDLINE]Related articles

Function and role of voltage-gated sodium channel NaV1.7 expressed in aortic smooth muscle cells.

Meguro K, Iida H, Takano H, Morita T, Sata M, Nagai R, Nakajima T.

Am J Physiol Heart Circ Physiol. 2009 Jan;296(1):H211-9. Epub 2008 Oct 31.PMID: 18978189 [PubMed - indexed for MEDLINE]Related articles

CD36 is one of important receptors promoting renal tubular injury by advanced oxidation protein products.

Iwao Y, Nakajou K, Nagai R, Kitamura K, Anraku M, Maruyama T, Otagiri M.

Am J Physiol Renal Physiol. 2008 Dec;295(6):F1871-80. Epub 2008 Oct 29.PMID: 18971214 [PubMed - indexed for MEDLINE]Related articles

Value of live 3D transoesophageal echocardiography in the diagnosis of mitral valve lesions.

Uno K, Takenaka K, Ebihara A, Nawata K, Hayashi N, Nagasaki M, Sonoda M, Takayuki O, Ono M, Kyo S, Nagai R, Takamoto S.

Eur J Echocardiogr. 2009 Mar;10(2):350-1. Epub 2008 Sep 11.PMID: 18786947 [PubMed - in process]Related articlesFree article

Identification of neutral cholesterol ester hydrolase, a key enzyme removing cholesterol from macrophages.

Okazaki H, Igarashi M, Nishi M, Sekiya M, Tajima M, Takase S, Takanashi M, Ohta K, Tamura Y, Okazaki S, Yahagi N, Ohashi K, Amemiya-Kudo M, Nakagawa Y, Nagai R, Kadowaki T, Osuga J, Ishibashi S.

J Biol Chem. 2008 Nov 28;283(48):33357-64. Epub 2008 Sep 9.PMID: 18782767 [PubMed - indexed for MEDLINE]Related articles

Recurrence of late-acquired incomplete stent apposition following sirolimus-eluting stent implantation.

Iwata H, Ako J, Nagai R.

J Invasive Cardiol. 2008 Sep;20(9):E265-8. Review.PMID: 18762685 [PubMed - indexed for MEDLINE]Related articles