PubMed

Symmetric signalling within asymmetric dimers of the Staphylococcus aureus receptor histidine kinase AgrC.

George Cisar EA, Geisinger E, Muir TW, Novick RP.

Mol Microbiol. 2009 Oct;74(1):44-57. Epub 2009 Aug 24.PMID: 19708918 [PubMed - in process]Related articles

Specificity of staphylococcal phage and SaPI DNA packaging as revealed by integrase and terminase mutations.

Ubeda C, Olivarez NP, Barry P, Wang H, Kong X, Matthews A, Tallent SM, Christie GE, Novick RP.

Mol Microbiol. 2009 Apr;72(1):98-108.PMID: 19347993 [PubMed - indexed for MEDLINE]Related articles

agr receptor mutants reveal distinct modes of inhibition by staphylococcal autoinducing peptides.

Geisinger E, Muir TW, Novick RP.

Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1216-21. Epub 2009 Jan 15.PMID: 19147840 [PubMed - indexed for MEDLINE]Related articlesFree article

Killing niche competitors by remote-control bacteriophage induction.

Selva L, Viana D, Regev-Yochay G, Trzcinski K, Corpa JM, Lasa I, Novick RP, Penadés JR.

Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1234-8. Epub 2009 Jan 13.PMID: 19141630 [PubMed - indexed for MEDLINE]Related articlesFree article

Phage-mediated intergeneric transfer of toxin genes.

Chen J, Novick RP.

Science. 2009 Jan 2;323(5910):139-41.PMID: 19119236 [PubMed - indexed for MEDLINE]Related articles

Prevalence of agr dysfunction among colonizing Staphylococcus aureus strains.

Shopsin B, Drlica-Wagner A, Mathema B, Adhikari RP, Kreiswirth BN, Novick RP.

J Infect Dis. 2008 Oct 15;198(8):1171-4.PMID: 18752431 [PubMed - indexed for MEDLINE]Related articles

Quorum sensing in staphylococci.

Novick RP, Geisinger E.

Annu Rev Genet. 2008;42:541-64. Review.PMID: 18713030 [PubMed - indexed for MEDLINE]Related articles

agr function in clinical Staphylococcus aureus isolates.

Traber KE, Lee E, Benson S, Corrigan R, Cantera M, Shopsin B, Novick RP.

Microbiology. 2008 Aug;154(Pt 8):2265-74.PMID: 18667559 [PubMed - indexed for MEDLINE]Related articlesFree article

Cyclic peptide inhibitors of staphylococcal virulence prepared by Fmoc-based thiolactone peptide synthesis.

George EA, Novick RP, Muir TW.

J Am Chem Soc. 2008 Apr 9;130(14):4914-24. Epub 2008 Mar 12.PMID: 18335939 [PubMed - indexed for MEDLINE]Related articles

Regulatory organization of the staphylococcal sae locus.

Adhikari RP, Novick RP.

Microbiology. 2008 Mar;154(Pt 3):949-59.PMID: 18310041 [PubMed - indexed for MEDLINE]Related articlesFree article

Medicine. Combating impervious bugs.

Novick RP.

Science. 2008 Feb 15;319(5865):910-1. No abstract available. PMID: 18276877 [PubMed - indexed for MEDLINE]Related articles

Staphylococcus aureus pathogenicity island DNA is packaged in particles composed of phage proteins.

Tormo MA, Ferrer MD, Maiques E, Ubeda C, Selva L, Lasa I, Calvete JJ, Novick RP, Penadés JR.

J Bacteriol. 2008 Apr;190(7):2434-40. Epub 2008 Jan 25.PMID: 18223072 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of ligand specificity determinants in AgrC, the Staphylococcus aureus quorum-sensing receptor.

Geisinger E, George EA, Muir TW, Novick RP.

J Biol Chem. 2008 Apr 4;283(14):8930-8. Epub 2008 Jan 25.PMID: 18222919 [PubMed - indexed for MEDLINE]Related articlesFree article

SaPI mutations affecting replication and transfer and enabling autonomous replication in the absence of helper phage.

Ubeda C, Maiques E, Barry P, Matthews A, Tormo MA, Lasa I, Novick RP, Penadés JR.

Mol Microbiol. 2008 Feb;67(3):493-503. Epub 2007 Dec 17.PMID: 18086210 [PubMed - indexed for MEDLINE]Related articles

Sequence analysis reveals genetic exchanges and intraspecific spread of SaPI2, a pathogenicity island involved in menstrual toxic shock.

Subedi A, Ubeda C, Adhikari RP, Penadés JR, Novick RP.

Microbiology. 2007 Oct;153(Pt 10):3235-45.PMID: 17906123 [PubMed - indexed for MEDLINE]Related articlesFree article

A pathogenicity island replicon in Staphylococcus aureus replicates as an unstable plasmid.

Ubeda C, Barry P, Penadés JR, Novick RP.

Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14182-8. Epub 2007 Aug 10.PMID: 17693549 [PubMed - indexed for MEDLINE]Related articlesFree article

A nonsense mutation in agrA accounts for the defect in agr expression and the avirulence of Staphylococcus aureus 8325-4 traP::kan.

Adhikari RP, Arvidson S, Novick RP.

Infect Immun. 2007 Sep;75(9):4534-40. Epub 2007 Jul 2.PMID: 17606604 [PubMed - indexed for MEDLINE]Related articlesFree article

SaPI operon I is required for SaPI packaging and is controlled by LexA.

Ubeda C, Maiques E, Tormo MA, Campoy S, Lasa I, Barbé J, Novick RP, Penadés JR.

Mol Microbiol. 2007 Jul;65(1):41-50.PMID: 17581119 [PubMed - indexed for MEDLINE]Related articles

Role of staphylococcal phage and SaPI integrase in intra- and interspecies SaPI transfer.

Maiques E, Ubeda C, Tormo MA, Ferrer MD, Lasa I, Novick RP, Penadés JR.

J Bacteriol. 2007 Aug;189(15):5608-16. Epub 2007 Jun 1.PMID: 17545290 [PubMed - indexed for MEDLINE]Related articlesFree article

svrA, a multi-drug exporter, does not control agr.

Chen J, Novick RP.

Microbiology. 2007 May;153(Pt 5):1604-8.PMID: 17464075 [PubMed - indexed for MEDLINE]Related articlesFree article

The SaPIs: mobile pathogenicity islands of Staphylococcus.

Novick RP, Subedi A.

Chem Immunol Allergy. 2007;93:42-57. Review.PMID: 17369699 [PubMed - indexed for MEDLINE]Related articles

Inhibition of rot translation by RNAIII, a key feature of agr function.

Geisinger E, Adhikari RP, Jin R, Ross HF, Novick RP.

Mol Microbiol. 2006 Aug;61(4):1038-48.PMID: 16879652 [PubMed - indexed for MEDLINE]Related articles

Use of targetrons to disrupt essential and nonessential genes in Staphylococcus aureus reveals temperature sensitivity of Ll.LtrB group II intron splicing.

Yao J, Zhong J, Fang Y, Geisinger E, Novick RP, Lambowitz AM.

RNA. 2006 Jul;12(7):1271-81. Epub 2006 Jun 1.PMID: 16741231 [PubMed - indexed for MEDLINE]Related articlesFree article

beta-lactam antibiotics induce the SOS response and horizontal transfer of virulence factors in Staphylococcus aureus.

Maiques E, Ubeda C, Campoy S, Salvador N, Lasa I, Novick RP, Barbé J, Penadés JR.

J Bacteriol. 2006 Apr;188(7):2726-9.PMID: 16547063 [PubMed - indexed for MEDLINE]Related articlesFree article

Interrupters on the bacterial party line.

Novick RP.

Nat Chem Biol. 2005 Nov;1(6):321-2. No abstract available. PMID: 16408068 [PubMed - indexed for MEDLINE]Related articles

Subinhibitory cerulenin inhibits staphylococcal exoprotein production by blocking transcription rather than by blocking secretion.

Adhikari RP, Novick RP.

Microbiology. 2005 Sep;151(Pt 9):3059-69.PMID: 16151216 [PubMed - indexed for MEDLINE]Related articlesFree article

The agr radiation: an early event in the evolution of staphylococci.

Wright JS 3rd, Traber KE, Corrigan R, Benson SA, Musser JM, Novick RP.

J Bacteriol. 2005 Aug;187(16):5585-94.PMID: 16077103 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced susceptibility of Staphylococcus aureus to vancomycin and platelet microbicidal protein correlates with defective autolysis and loss of accessory gene regulator (agr) function.

Sakoulas G, Eliopoulos GM, Fowler VG Jr, Moellering RC Jr, Novick RP, Lucindo N, Yeaman MR, Bayer AS.

Antimicrob Agents Chemother. 2005 Jul;49(7):2687-92.PMID: 15980337 [PubMed - indexed for MEDLINE]Related articlesFree article

Staphylococcus intermedius produces a functional agr autoinducing peptide containing a cyclic lactone.

Ji G, Pei W, Zhang L, Qiu R, Lin J, Benito Y, Lina G, Novick RP.

J Bacteriol. 2005 May;187(9):3139-50.PMID: 15838041 [PubMed - indexed for MEDLINE]Related articlesFree article

Antibiotic-induced SOS response promotes horizontal dissemination of pathogenicity island-encoded virulence factors in staphylococci.

Ubeda C, Maiques E, Knecht E, Lasa I, Novick RP, Penadés JR.

Mol Microbiol. 2005 May;56(3):836-44.PMID: 15819636 [PubMed - indexed for MEDLINE]Related articles

Transient interference with staphylococcal quorum sensing blocks abscess formation.

Wright JS 3rd, Jin R, Novick RP.

Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1691-6. Epub 2005 Jan 21.PMID: 15665088 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of mild acid on gene expression in Staphylococcus aureus.

Weinrick B, Dunman PM, McAleese F, Murphy E, Projan SJ, Fang Y, Novick RP.

J Bacteriol. 2004 Dec;186(24):8407-23.PMID: 15576791 [PubMed - indexed for MEDLINE]Related articlesFree article

Hydrophobic interactions drive ligand-receptor recognition for activation and inhibition of staphylococcal quorum sensing.

Wright JS 3rd, Lyon GJ, George EA, Muir TW, Novick RP.

Proc Natl Acad Sci U S A. 2004 Nov 16;101(46):16168-73. Epub 2004 Nov 4.PMID: 15528279 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel cassette-based shuttle vector system for gram-positive bacteria.

Charpentier E, Anton AI, Barry P, Alfonso B, Fang Y, Novick RP.

Appl Environ Microbiol. 2004 Oct;70(10):6076-85.PMID: 15466553 [PubMed - indexed for MEDLINE]Related articlesFree article

Synthesis of group A streptococcal virulence factors is controlled by a regulatory RNA molecule.

Mangold M, Siller M, Roppenser B, Vlaminckx BJ, Penfound TA, Klein R, Novak R, Novick RP, Charpentier E.

Mol Microbiol. 2004 Sep;53(5):1515-27.PMID: 15387826 [PubMed - indexed for MEDLINE]Related articles

Peptide signaling in Staphylococcus aureus and other Gram-positive bacteria.

Lyon GJ, Novick RP.

Peptides. 2004 Sep;25(9):1389-403. Review.PMID: 15374643 [PubMed - indexed for MEDLINE]Related articles

Distinguishing human ethnic groups by means of sequences from Helicobacter pylori: lessons from Ladakh.

Wirth T, Wang X, Linz B, Novick RP, Lum JK, Blaser M, Morelli G, Falush D, Achtman M.

Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):4746-51. Epub 2004 Mar 29.PMID: 15051885 [PubMed - indexed for MEDLINE]Related articlesFree article

Systemic tumor targeting and killing by Sindbis viral vectors.

Tseng JC, Levin B, Hurtado A, Yee H, Perez de Castro I, Jimenez M, Shamamian P, Jin R, Novick RP, Pellicer A, Meruelo D.

Nat Biotechnol. 2004 Jan;22(1):70-7. Epub 2003 Nov 30.PMID: 14647305 [PubMed - indexed for MEDLINE]Related articles

The staphylococcal saeRS system coordinates environmental signals with agr quorum sensing.

Novick RP, Jiang D.

Microbiology. 2003 Oct;149(Pt 10):2709-17.PMID: 14523104 [PubMed - indexed for MEDLINE]Related articlesFree article

Autoinduction and signal transduction in the regulation of staphylococcal virulence.

Novick RP.

Mol Microbiol. 2003 Jun;48(6):1429-49. Review.PMID: 12791129 [PubMed - indexed for MEDLINE]Related articles

Mobile genetic elements and bacterial toxinoses: the superantigen-encoding pathogenicity islands of Staphylococcus aureus.

Novick RP.

Plasmid. 2003 Mar;49(2):93-105. Review.PMID: 12726763 [PubMed - indexed for MEDLINE]Related articles

Staphylococcus aureus accessory gene regulator (agr) group II: is there a relationship to the development of intermediate-level glycopeptide resistance?

Sakoulas G, Eliopoulos GM, Moellering RC Jr, Novick RP, Venkataraman L, Wennersten C, DeGirolami PC, Schwaber MJ, Gold HS.

J Infect Dis. 2003 Mar 15;187(6):929-38. Epub 2003 Mar 6.PMID: 12660939 [PubMed - indexed for MEDLINE]Related articles

Responses of endoscopy patients in Ladakh, India, to Helicobacter pylori whole-cell and Cag A antigens.

Romero-Gallo J, Pérez-Pérez GI, Novick RP, Kamath P, Norbu T, Blaser MJ.

Clin Diagn Lab Immunol. 2002 Nov;9(6):1313-7.PMID: 12414766 [PubMed - indexed for MEDLINE]Related articlesFree article

Key determinants of receptor activation in the agr autoinducing peptides of Staphylococcus aureus.

Lyon GJ, Wright JS, Muir TW, Novick RP.

Biochemistry. 2002 Aug 6;41(31):10095-104.PMID: 12146974 [PubMed - indexed for MEDLINE]Related articles

Transmembrane topology of AgrB, the protein involved in the post-translational modification of AgrD in Staphylococcus aureus.

Zhang L, Gray L, Novick RP, Ji G.

J Biol Chem. 2002 Sep 20;277(38):34736-42. Epub 2002 Jul 16.PMID: 12122003 [PubMed - indexed for MEDLINE]Related articlesFree article

Global repression of exotoxin synthesis by staphylococcal superantigens.

Vojtov N, Ross HF, Novick RP.

Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):10102-7. Epub 2002 Jul 10.PMID: 12110733 [PubMed - indexed for MEDLINE]Related articlesFree article

Accessory gene regulator (agr) locus in geographically diverse Staphylococcus aureus isolates with reduced susceptibility to vancomycin.

Sakoulas G, Eliopoulos GM, Moellering RC Jr, Wennersten C, Venkataraman L, Novick RP, Gold HS.

Antimicrob Agents Chemother. 2002 May;46(5):1492-502.PMID: 11959587 [PubMed - indexed for MEDLINE]Related articlesFree article

High genetic variability of the agr locus in Staphylococcus species.

Dufour P, Jarraud S, Vandenesch F, Greenland T, Novick RP, Bes M, Etienne J, Lina G.

J Bacteriol. 2002 Feb;184(4):1180-6.PMID: 11807079 [PubMed - indexed for MEDLINE]Related articlesFree article

Reversible and specific extracellular antagonism of receptor-histidine kinase signaling.

Lyon GJ, Wright JS, Christopoulos A, Novick RP, Muir TW.

J Biol Chem. 2002 Feb 22;277(8):6247-53. Epub 2001 Dec 3.PMID: 11733525 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of the double-strand origin cruciform in pT181 replication.

Jin R, Novick RP.

Plasmid. 2001 Sep;46(2):95-105.PMID: 11591135 [PubMed - indexed for MEDLINE]Related articles