PubMed

HLA class I antibodies provoke graft arteriosclerosis in human arteries transplanted into SCID/beige mice.

Galvani S, Augé N, Calise D, Thiers JC, Canivet C, Kamar N, Rostaing L, Abbal M, Sallusto F, Salvayre R, Böhler T, Zou Y, Stastny P, Nègre-Salvayre A, Thomsen M.

Am J Transplant. 2009 Nov;9(11):2607-14.PMID: 19843036 [PubMed - in process]Related articles

Integrin alpha(v)beta(3), metalloproteinases, and sphingomyelinase-2 mediate urokinase mitogenic effect.

Maupas-Schwalm F, Bedel A, Augé N, Grazide MH, Mucher E, Thiers JC, Salvayre R, Nègre-Salvayre A.

Cell Signal. 2009 Dec;21(12):1925-34. Epub 2009 Sep 6.PMID: 19735728 [PubMed - in process]Related articles

Hyperglycemia and glycation in diabetic complications.

Negre-Salvayre A, Salvayre R, Augé N, Pamplona R, Portero-Otín M.

Antioxid Redox Signal. 2009 Dec;11(12):3071-109.PMID: 19489690 [PubMed - in process]Related articles

Polyoma BK virus-associated nephropathy in kidney-transplant patients: Effects of leflunomide on T-cell functions and disease outcome.

Canivet C, Rostaing L, Galvani S, Böhler T, Gandia P, Mengelle C, Guilbeau-Frugier C, Thomsen M, Salvayre R, Negre-Salvayre A, Kamar N.

Int Immunopharmacol. 2009 Aug;9(9):1131-6. Epub 2009 May 13.PMID: 19446045 [PubMed - in process]Related articles

FTY720 Inhibits Tumor Necrosis Factor-alpha-Induced Proliferation and Extracellular Signal-Regulated Kinase Phosphorylation of Human Smooth Muscle Cells.

Böhler T, Kamar N, Etienne L, Galvani S, Canivet C, Thomsen M, Salvayre R, Nègre-Salvayre A, Rostaing L, Auge N.

Transplant Proc. 2009 Mar;41(2):705-6.PMID: 19328962 [PubMed - indexed for MEDLINE]Related articles

Small, dense HDL3 particles attenuates apoptosis in endothelial cells: Pivotal role of apolipoprotein A-I.

de Souza JA, Vindis C, Nègre-Salvayre A, Rye KA, Couturier M, Therond P, Chantepie S, Salvayre R, Chapman MJ, Kontush A.

J Cell Mol Med. 2009 Feb 20. [Epub ahead of print]PMID: 19243471 [PubMed - as supplied by publisher]Related articles

Cytokines correlate with age in healthy volunteers, dialysis patients and kidney-transplant patients.

Böhler T, Canivet C, Nguyen PN, Galvani S, Thomsen M, Durand D, Salvayre R, Negre-Salvayre A, Rostaing L, Kamar N.

Cytokine. 2009 Mar;45(3):169-73. Epub 2009 Jan 14.PMID: 19147373 [PubMed - indexed for MEDLINE]Related articles

Resveratrol inhibits the mTOR mitogenic signaling evoked by oxidized LDL in smooth muscle cells.

Brito PM, Devillard R, Nègre-Salvayre A, Almeida LM, Dinis TC, Salvayre R, Augé N.

Atherosclerosis. 2009 Jul;205(1):126-34. Epub 2008 Nov 24.PMID: 19108833 [PubMed - indexed for MEDLINE]Related articles

Oxidized low-density lipoproteins trigger endoplasmic reticulum stress in vascular cells: prevention by oxygen-regulated protein 150 expression.

Sanson M, Augé N, Vindis C, Muller C, Bando Y, Thiers JC, Marachet MA, Zarkovic K, Sawa Y, Salvayre R, Nègre-Salvayre A.

Circ Res. 2009 Feb 13;104(3):328-36. Epub 2008 Dec 23.PMID: 19106412 [PubMed - indexed for MEDLINE]Related articles

TRPC1 is regulated by caveolin-1 and is involved in oxidized LDL-induced apoptosis of vascular smooth muscle cells.

Ingueneau C, Huynh-Do U, Marcheix B, Athias A, Gambert P, Nègre-Salvayre A, Salvayre R, Vindis C.

J Cell Mol Med. 2008 Nov 14. [Epub ahead of print]PMID: 19040417 [PubMed - as supplied by publisher]Related articles

Carbonyl scavenger and antiatherogenic effects of hydrazine derivatives.

Galvani S, Coatrieux C, Elbaz M, Grazide MH, Thiers JC, Parini A, Uchida K, Kamar N, Rostaing L, Baltas M, Salvayre R, Nègre-Salvayre A.

Free Radic Biol Med. 2008 Nov 15;45(10):1457-67. Epub 2008 Sep 9.PMID: 18801426 [PubMed - indexed for MEDLINE]Related articles

E-cadherin/beta-catenin/T-cell factor pathway is involved in smooth muscle cell proliferation elicited by oxidized low-density lipoprotein.

Bedel A, Nègre-Salvayre A, Heeneman S, Grazide MH, Thiers JC, Salvayre R, Maupas-Schwalm F.

Circ Res. 2008 Sep 26;103(7):694-701. Epub 2008 Aug 14.PMID: 18703780 [PubMed - indexed for MEDLINE]Related articlesFree article

In vitro mitogen-stimulated T-cell from hepatitis C virus-positive liver transplantation candidates, increases T-cell activation markers and T-cell proliferation.

Canivet C, Böhler T, Galvani S, Péron JM, Muscari F, Alric L, Barange K, Salvayre R, Negre-Salvayre A, Durand D, Suc B, Izopet J, Thomsen M, Rostaing L, Kamar N.

Transpl Immunol. 2008 May;19(2):112-9. Epub 2008 Apr 3.PMID: 18503886 [PubMed - indexed for MEDLINE]Related articles

Development of novel antiatherogenic biaryls: design, synthesis, and reactivity.

Delomenède M, Bedos-Belval F, Duran H, Vindis C, Baltas M, Nègre-Salvayre A.

J Med Chem. 2008 Jun 12;51(11):3171-81. Epub 2008 May 9.PMID: 18465848 [PubMed - indexed for MEDLINE]Related articles

Oxygen-regulated protein-150 prevents calcium homeostasis deregulation and apoptosis induced by oxidized LDL in vascular cells.

Sanson M, Ingueneau C, Vindis C, Thiers JC, Glock Y, Rousseau H, Sawa Y, Bando Y, Mallat Z, Salvayre R, Nègre-Salvayre A.

Cell Death Differ. 2008 Aug;15(8):1255-65. Epub 2008 Apr 11.PMID: 18404158 [PubMed - indexed for MEDLINE]Related articlesFree article

Pharmacodynamic monitoring of the conversion from mycophenolate mofetil to enteric-coated mycophenolate sodium in stable kidney-allograft recipients.

Böhler T, Canivet C, Galvani S, Therville N, Salvayre R, Negre-Salvayre A, Durand D, Thomsen M, Rostaing L, Kamar N.

Int Immunopharmacol. 2008 May;8(5):769-73. Epub 2008 Feb 20.PMID: 18387521 [PubMed - indexed for MEDLINE]Related articles

Caveolin-1 sensitizes vascular smooth muscle cells to mildly oxidized LDL-induced apoptosis.

Ingueneau C, Huynh-Do U, Thiers JC, Nègre-Salvayre A, Salvayre R, Vindis C.

Biochem Biophys Res Commun. 2008 May 9;369(3):889-93. Epub 2008 Mar 6.PMID: 18328807 [PubMed - indexed for MEDLINE]Related articles

Effect of FTY720 on apoptosis of smooth muscle cells.

Böhler T, Guillebaud J, Etienne L, Canivet C, Kamar N, Rostaing L, Thiers JC, Galvani S, Augé N, Salvayre R, Nègre-Salvayre A, Thomsen M.

Transplant Proc. 2007 Oct;39(8):2624-6.PMID: 17954194 [PubMed - indexed for MEDLINE]Related articles

Metabolic syndrome features small, apolipoprotein A-I-poor, triglyceride-rich HDL3 particles with defective anti-apoptotic activity.

de Souza JA, Vindis C, Hansel B, Nègre-Salvayre A, Therond P, Serrano CV Jr, Chantepie S, Salvayre R, Bruckert E, Chapman MJ, Kontush A.

Atherosclerosis. 2008 Mar;197(1):84-94. Epub 2007 Sep 14.PMID: 17868679 [PubMed - indexed for MEDLINE]Related articles

Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors.

Negre-Salvayre A, Coatrieux C, Ingueneau C, Salvayre R.

Br J Pharmacol. 2008 Jan;153(1):6-20. Epub 2007 Jul 23. Review.PMID: 17643134 [PubMed - indexed for MEDLINE]Related articlesFree article

[Neutral lipid storage diseases and ATGL (adipose triglyceride lipase) and CGI-58/ABHD5 (alpha-beta hydrolase domain-containing 5) deficiency: myopathy, ichthyosis, but no obesity]

Fischer J, Negre-Salvayre A, Salvayre R.

Med Sci (Paris). 2007 Jun-Jul;23(6-7):575-8. French. No abstract available. PMID: 17631826 [PubMed - indexed for MEDLINE]Related articles

Synthesis of ferulic ester dimers, functionalisation and biological evaluation as potential antiatherogenic and antiplasmodial agents.

Rakotondramanana DL, Delomenède M, Baltas M, Duran H, Bedos-Belval F, Rasoanaivo P, Negre-Salvayre A, Gornitzka H.

Bioorg Med Chem. 2007 Sep 15;15(18):6018-26. Epub 2007 Jun 29.PMID: 17624792 [PubMed - indexed for MEDLINE]Related articles

Preferential sphingosine-1-phosphate enrichment and sphingomyelin depletion are key features of small dense HDL3 particles: relevance to antiapoptotic and antioxidative activities.

Kontush A, Therond P, Zerrad A, Couturier M, Négre-Salvayre A, de Souza JA, Chantepie S, Chapman MJ.

Arterioscler Thromb Vasc Biol. 2007 Aug;27(8):1843-9. Epub 2007 Jun 14.PMID: 17569880 [PubMed - indexed for MEDLINE]Related articlesFree article

MAO-A-induced mitogenic signaling is mediated by reactive oxygen species, MMP-2, and the sphingolipid pathway.

Coatrieux C, Sanson M, Negre-Salvayre A, Parini A, Hannun Y, Itohara S, Salvayre R, Auge N.

Free Radic Biol Med. 2007 Jul 1;43(1):80-9. Epub 2007 Apr 10.PMID: 17561096 [PubMed - indexed for MEDLINE]Related articles

Methylglyoxal induces advanced glycation end product (AGEs) formation and dysfunction of PDGF receptor-beta: implications for diabetic atherosclerosis.

Cantero AV, Portero-Otín M, Ayala V, Auge N, Sanson M, Elbaz M, Thiers JC, Pamplona R, Salvayre R, Nègre-Salvayre A.

FASEB J. 2007 Oct;21(12):3096-106. Epub 2007 May 15.PMID: 17504976 [PubMed - indexed for MEDLINE]Related articlesFree article

Role for furin in tumor necrosis factor alpha-induced activation of the matrix metalloproteinase/sphingolipid mitogenic pathway.

Tellier E, Nègre-Salvayre A, Bocquet B, Itohara S, Hannun YA, Salvayre R, Augé N.

Mol Cell Biol. 2007 Apr;27(8):2997-3007. Epub 2007 Feb 5.PMID: 17283058 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipid oxidation products and oxidized low-density lipoproteins impair platelet-derived growth factor receptor activity in smooth muscle cells: implication in atherosclerosis.

Vindis C, Escargueil-Blanc I, Uchida K, Elbaz M, Salvayre R, Negre-Salvayre A.

Redox Rep. 2007;12(1):96-100.PMID: 17263919 [PubMed - indexed for MEDLINE]Related articles

The gene encoding adipose triglyceride lipase (PNPLA2) is mutated in neutral lipid storage disease with myopathy.

Fischer J, Lefèvre C, Morava E, Mussini JM, Laforêt P, Negre-Salvayre A, Lathrop M, Salvayre R.

Nat Genet. 2007 Jan;39(1):28-30. Epub 2006 Dec 24.PMID: 17187067 [PubMed - indexed for MEDLINE]Related articles

Simultaneous determination of allantoin, hypoxanthine, xanthine, and uric acid in serum/plasma by CE.

Caussé E, Pradelles A, Dirat B, Negre-Salvayre A, Salvayre R, Couderc F.

Electrophoresis. 2007 Feb;28(3):381-7.PMID: 17177243 [PubMed - indexed for MEDLINE]Related articles

Antioxidant and cytoprotective properties of high-density lipoproteins in vascular cells.

Negre-Salvayre A, Dousset N, Ferretti G, Bacchetti T, Curatola G, Salvayre R.

Free Radic Biol Med. 2006 Oct 1;41(7):1031-40. Epub 2006 Jul 12. Review.PMID: 16962927 [PubMed - indexed for MEDLINE]Related articles

Desensitization of platelet-derived growth factor receptor-beta by oxidized lipids in vascular cells and atherosclerotic lesions: prevention by aldehyde scavengers.

Vindis C, Escargueil-Blanc I, Elbaz M, Marcheix B, Grazide MH, Uchida K, Salvayre R, Nègre-Salvayre A.

Circ Res. 2006 Mar 31;98(6):785-92. Epub 2006 Mar 9.PMID: 16527993 [PubMed - indexed for MEDLINE]Related articlesFree article

Design, synthesis, and evaluation of pharmacological properties of cinnamic derivatives as antiatherogenic agents.

Lapeyre C, Delomenède M, Bedos-Belval F, Duran H, Nègre-Salvayre A, Baltas M.

J Med Chem. 2005 Dec 29;48(26):8115-24.PMID: 16366593 [PubMed - indexed for MEDLINE]Related articles

The grape-derived polyphenol resveratrol differentially affects epidermal and platelet-derived growth factor signaling in human liver myofibroblasts.

Godichaud S, Si-Tayeb K, Augé N, Desmoulière A, Balabaud C, Payrastre B, Nègre-Salvayre A, Rosenbaum J.

Int J Biochem Cell Biol. 2006;38(4):629-37. Epub 2005 Nov 28.PMID: 16343977 [PubMed - indexed for MEDLINE]Related articles

Chlamydia pneumoniae alters mildly oxidized low-density lipoprotein-induced cell death in human endothelial cells, leading to necrosis rather than apoptosis.

Nazzal D, Cantero AV, Therville N, Segui B, Negre-Salvayre A, Thomsen M, Benoist H.

J Infect Dis. 2006 Jan 1;193(1):136-45. Epub 2005 Nov 29.PMID: 16323142 [PubMed - indexed for MEDLINE]Related articles

Structural modifications of HDL and functional consequences.

Ferretti G, Bacchetti T, Nègre-Salvayre A, Salvayre R, Dousset N, Curatola G.

Atherosclerosis. 2006 Jan;184(1):1-7. Epub 2005 Sep 12. Review.PMID: 16157342 [PubMed - indexed for MEDLINE]Related articles

Effect of 4-hydroxynonenal on phosphatidylethanolamine containing condensed monolayer and on its interaction with apolipoprotein A-I.

Lecompte MF, Clavilier J, Rolland C, Collet X, Nègre-Salvayre A, Salvayre R.

FEBS Lett. 2005 Sep 12;579(22):5074-8.PMID: 16139275 [PubMed - indexed for MEDLINE]Related articles

A deletion in the gene encoding sphingomyelin phosphodiesterase 3 (Smpd3) results in osteogenesis and dentinogenesis imperfecta in the mouse.

Aubin I, Adams CP, Opsahl S, Septier D, Bishop CE, Auge N, Salvayre R, Negre-Salvayre A, Goldberg M, Guénet JL, Poirier C.

Nat Genet. 2005 Aug;37(8):803-5. Epub 2005 Jul 17.PMID: 16025116 [PubMed - indexed for MEDLINE]Related articles

High-density lipoproteins prevent the oxidized low-density lipoprotein-induced epidermal [corrected] growth factor receptor activation and subsequent matrix metalloproteinase-2 upregulation.

Robbesyn F, Augé N, Vindis C, Cantero AV, Barbaras R, Negre-Salvayre A, Salvayre R.

Arterioscler Thromb Vasc Biol. 2005 Jun;25(6):1206-12. Epub 2005 Apr 7. Erratum in: Arterioscler Thromb Vasc Biol. 2005 Aug;25(8):e128. PMID: 15817880 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of the {beta}-catenin/T-cell-specific transcription factor/lymphoid enhancer factor-1 pathway by plasminogen activators in ECV304 carcinoma cells.

Maupas-Schwalm F, Robinet C, Augé N, Thiers JC, Garcia V, Cambus JP, Salvayre R, Nègre-Salvayre A.

Cancer Res. 2005 Jan 15;65(2):526-32.PMID: 15695395 [PubMed - indexed for MEDLINE]Related articlesFree article

Two distinct calcium-dependent mitochondrial pathways are involved in oxidized LDL-induced apoptosis.

Vindis C, Elbaz M, Escargueil-Blanc I, Augé N, Heniquez A, Thiers JC, Nègre-Salvayre A, Salvayre R.

Arterioscler Thromb Vasc Biol. 2005 Mar;25(3):639-45. Epub 2004 Dec 23.PMID: 15618541 [PubMed - indexed for MEDLINE]Related articlesFree article

Dual role of oxidized LDL on the NF-kappaB signaling pathway.

Robbesyn F, Salvayre R, Negre-Salvayre A.

Free Radic Res. 2004 Jun;38(6):541-51. Review.PMID: 15346645 [PubMed - indexed for MEDLINE]Related articles

REDD2 gene is upregulated by modified LDL or hypoxia and mediates human macrophage cell death.

Cuaz-Pérolin C, Furman C, Larigauderie G, Legedz L, Lasselin C, Copin C, Jaye M, Searfoss G, Yu KT, Duverger N, Nègre-Salvayre A, Fruchart JC, Rouis M.

Arterioscler Thromb Vasc Biol. 2004 Oct;24(10):1830-5. Epub 2004 Aug 12.PMID: 15308555 [PubMed - indexed for MEDLINE]Related articlesFree article

Role for matrix metalloproteinase-2 in oxidized low-density lipoprotein-induced activation of the sphingomyelin/ceramide pathway and smooth muscle cell proliferation.

Augé N, Maupas-Schwalm F, Elbaz M, Thiers JC, Waysbort A, Itohara S, Krell HW, Salvayre R, Nègre-Salvayre A.

Circulation. 2004 Aug 3;110(5):571-8. Epub 2004 Jul 26.PMID: 15277330 [PubMed - indexed for MEDLINE]Related articlesFree article

The sphingomyelin/ceramide pathway is involved in ERK1/2 phosphorylation, cell proliferation, and uPAR overexpression induced by tissue-type plasminogen activator.

Maupas-Schwalm F, Augé N, Robinet C, Cambus JP, Parsons SJ, Salvayre R, Nègre-Salvayre A.

FASEB J. 2004 Sep;18(12):1398-400. Epub 2004 Jul 1.PMID: 15231724 [PubMed - indexed for MEDLINE]Related articlesFree article

Proliferation and wound healing of vascular cells trigger the generation of extracellular reactive oxygen species and LDL oxidation.

Duval C, Cantero AV, Auge N, Mabile L, Thiers JC, Negre-Salvayre A, Salvayre R.

Free Radic Biol Med. 2003 Dec 15;35(12):1589-98.PMID: 14680682 [PubMed - indexed for MEDLINE]Related articles

Oxidized LDL and 4-hydroxynonenal modulate tyrosine kinase receptor activity.

Negre-Salvayre A, Vieira O, Escargueil-Blanc I, Salvayre R.

Mol Aspects Med. 2003 Aug-Oct;24(4-5):251-61. Review.PMID: 12893003 [PubMed - indexed for MEDLINE]Related articles

Pancreatic bile salt-dependent lipase induces smooth muscle cells proliferation.

Augé N, Rebaï O, Lepetit-Thévenin J, Bruneau N, Thiers JC, Mas E, Lombardo D, Negre-Salvayre A, Vérine A.

Circulation. 2003 Jul 8;108(1):86-91. Epub 2003 Jun 23.PMID: 12821548 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitochondria play a central role in apoptosis induced by alpha-tocopheryl succinate, an agent with antineoplastic activity: comparison with receptor-mediated pro-apoptotic signaling.

Weber T, Dalen H, Andera L, Nègre-Salvayre A, Augé N, Sticha M, Lloret A, Terman A, Witting PK, Higuchi M, Plasilova M, Zivny J, Gellert N, Weber C, Neuzil J.

Biochemistry. 2003 Apr 15;42(14):4277-91.PMID: 12680782 [PubMed - indexed for MEDLINE]Related articles

Impairment of the cytotoxic and oxidative activities of 7 beta-hydroxycholesterol and 7-ketocholesterol by esterification with oleate.

Monier S, Samadi M, Prunet C, Denance M, Laubriet A, Athias A, Berthier A, Steinmetz E, Jürgens G, Nègre-Salvayre A, Bessède G, Lemaire-Ewing S, Néel D, Gambert P, Lizard G.

Biochem Biophys Res Commun. 2003 Apr 11;303(3):814-24.PMID: 12670484 [PubMed - indexed for MEDLINE]Related articles

HDL counterbalance the proinflammatory effect of oxidized LDL by inhibiting intracellular reactive oxygen species rise, proteasome activation, and subsequent NF-kappaB activation in smooth muscle cells.

Robbesyn F, Garcia V, Auge N, Vieira O, Frisach MF, Salvayre R, Negre-Salvayre A.

FASEB J. 2003 Apr;17(6):743-5. Epub 2003 Feb 5.PMID: 12586748 [PubMed - indexed for MEDLINE]Related articlesFree article