PubMed

Purification and characterization of mammalian glucose transporters expressed in Pichia pastoris.

Alisio A, Mueckler M.

Protein Expr Purif. 2009 Oct 31. [Epub ahead of print]PMID: 19883765 [PubMed - as supplied by publisher]Related articles

Model of the exofacial substrate-binding site and helical folding of the human Glut1 glucose transporter based on scanning mutagenesis.

Mueckler M, Makepeace C.

Biochemistry. 2009 Jun 30;48(25):5934-42.PMID: 19449892 [PubMed - indexed for MEDLINE]Related articles

Identification of amino acid residues within the C terminus of the Glut4 glucose transporter that are essential for insulin-stimulated redistribution to the plasma membrane.

Song XM, Hresko RC, Mueckler M.

J Biol Chem. 2008 May 2;283(18):12571-85. Epub 2008 Feb 27.PMID: 18305115 [PubMed - indexed for MEDLINE]Related articlesFree article

Transmembrane segment 6 of the Glut1 glucose transporter is an outer helix and contains amino acid side chains essential for transport activity.

Mueckler M, Makepeace C.

J Biol Chem. 2008 Apr 25;283(17):11550-5. Epub 2008 Feb 1.PMID: 18245775 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of lipopolysaccharide-induced increases in neutrophil glucose uptake.

Schuster DP, Brody SL, Zhou Z, Bernstein M, Arch R, Link D, Mueckler M.

Am J Physiol Lung Cell Mol Physiol. 2007 Apr;292(4):L845-51. Epub 2006 Nov 22.PMID: 17122354 [PubMed - indexed for MEDLINE]Related articlesFree article

Transmembrane segment 12 of the Glut1 glucose transporter is an outer helix and is not directly involved in the transport mechanism.

Mueckler M, Makepeace C.

J Biol Chem. 2006 Dec 1;281(48):36993-8. Epub 2006 Oct 3.PMID: 17020877 [PubMed - indexed for MEDLINE]Related articlesFree article

mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes.

Hresko RC, Mueckler M.

J Biol Chem. 2005 Dec 9;280(49):40406-16. Epub 2005 Oct 11.PMID: 16221682 [PubMed - indexed for MEDLINE]Related articlesFree article

Cysteine-scanning mutagenesis and substituted cysteine accessibility analysis of transmembrane segment 4 of the Glut1 glucose transporter.

Mueckler M, Makepeace C.

J Biol Chem. 2005 Nov 25;280(47):39562-8. Epub 2005 Sep 19.PMID: 16172126 [PubMed - indexed for MEDLINE]Related articlesFree article

Transmembrane segment 3 of the Glut1 glucose transporter is an outer helix.

Mueckler M, Roach W, Makepeace C.

J Biol Chem. 2004 Nov 5;279(45):46876-81. Epub 2004 Aug 10.PMID: 15308632 [PubMed - indexed for MEDLINE]Related articlesFree article

Relative proximity and orientation of helices 4 and 8 of the GLUT1 glucose transporter.

Alisio A, Mueckler M.

J Biol Chem. 2004 Jun 18;279(25):26540-5. Epub 2004 Apr 7.PMID: 15073187 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of transmembrane segment 8 of the GLUT1 glucose transporter by cysteine-scanning mutagenesis and substituted cysteine accessibility.

Mueckler M, Makepeace C.

J Biol Chem. 2004 Mar 12;279(11):10494-9. Epub 2003 Dec 19.PMID: 14688257 [PubMed - indexed for MEDLINE]Related articlesFree article

Wolframin expression induces novel ion channel activity in endoplasmic reticulum membranes and increases intracellular calcium.

Osman AA, Saito M, Makepeace C, Permutt MA, Schlesinger P, Mueckler M.

J Biol Chem. 2003 Dec 26;278(52):52755-62. Epub 2003 Oct 3.PMID: 14527944 [PubMed - indexed for MEDLINE]Related articlesFree article

Reconstitution of phosphoinositide 3-kinase-dependent insulin signaling in a cell-free system.

Murata H, Hresko RC, Mueckler M.

J Biol Chem. 2003 Jun 13;278(24):21607-14. Epub 2003 Apr 7.PMID: 12682058 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphoinositide-dependent kinase-2 is a distinct protein kinase enriched in a novel cytoskeletal fraction associated with adipocyte plasma membranes.

Hresko RC, Murata H, Mueckler M.

J Biol Chem. 2003 Jun 13;278(24):21615-22. Epub 2003 Apr 7.PMID: 12682057 [PubMed - indexed for MEDLINE]Related articlesFree article

Investigating the cellular targets of HIV protease inhibitors: implications for metabolic disorders and improvements in drug therapy.

Murata H, Hruz PW, Mueckler M.

Curr Drug Targets Infect Disord. 2002 Mar;2(1):1-8. Review.PMID: 12462148 [PubMed - indexed for MEDLINE]Related articles

Enhanced O-GlcNAc protein modification is associated with insulin resistance in GLUT1-overexpressing muscles.

Buse MG, Robinson KA, Marshall BA, Hresko RC, Mueckler MM.

Am J Physiol Endocrinol Metab. 2002 Aug;283(2):E241-50.PMID: 12110528 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of pp68 as the Tyrosine-phosphorylated Form of SYNCRIP/NSAP1. A cytoplasmic RNA-binding protein.

Hresko RC, Mueckler M.

J Biol Chem. 2002 Jul 12;277(28):25233-8. Epub 2002 May 6.PMID: 11994298 [PubMed - indexed for MEDLINE]Related articlesFree article

Indinavir inhibits the glucose transporter isoform Glut4 at physiologic concentrations.

Murata H, Hruz PW, Mueckler M.

AIDS. 2002 Apr 12;16(6):859-63.PMID: 11919487 [PubMed - indexed for MEDLINE]Related articles

Indinavir induces acute and reversible peripheral insulin resistance in rats.

Hruz PW, Murata H, Qiu H, Mueckler M.

Diabetes. 2002 Apr;51(4):937-42.PMID: 11916910 [PubMed - indexed for MEDLINE]Related articlesFree article

Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators.

Joost HG, Bell GI, Best JD, Birnbaum MJ, Charron MJ, Chen YT, Doege H, James DE, Lodish HF, Moley KH, Moley JF, Mueckler M, Rogers S, Schürmann A, Seino S, Thorens B.

Am J Physiol Endocrinol Metab. 2002 Apr;282(4):E974-6.PMID: 11882521 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of transmembrane segment 10 of the Glut1 glucose transporter by cysteine-scanning mutagenesis and substituted cysteine accessibility.

Mueckler M, Makepeace C.

J Biol Chem. 2002 Feb 1;277(5):3498-503. Epub 2001 Nov 16.PMID: 11713254 [PubMed - indexed for MEDLINE]Related articlesFree article

Structural analysis of the GLUT1 facilitative glucose transporter (review).

Hruz PW, Mueckler MM.

Mol Membr Biol. 2001 Jul-Sep;18(3):183-93. Review.PMID: 11681785 [PubMed - indexed for MEDLINE]Related articles

Insulin resistance and the disruption of Glut4 trafficking in skeletal muscle.

Mueckler M.

J Clin Invest. 2001 May;107(10):1211-3. No abstract available. PMID: 11375407 [PubMed - indexed for MEDLINE]Related articlesFree article

Adverse metabolic consequences of HIV protease inhibitor therapy: the search for a central mechanism.

Hruz PW, Murata H, Mueckler M.

Am J Physiol Endocrinol Metab. 2001 Apr;280(4):E549-53. Review.PMID: 11254460 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose transport and apoptosis.

Moley KH, Mueckler MM.

Apoptosis. 2000 Apr;5(2):99-105. Review.PMID: 11232248 [PubMed - indexed for MEDLINE]Related articles

Cysteine-scanning mutagenesis of transmembrane segment 11 of the GLUT1 facilitative glucose transporter.

Hruz PW, Mueckler MM.

Biochemistry. 2000 Aug 8;39(31):9367-72.PMID: 10924131 [PubMed - indexed for MEDLINE]Related articles

GLUT8 is a glucose transporter responsible for insulin-stimulated glucose uptake in the blastocyst.

Carayannopoulos MO, Chi MM, Cui Y, Pingsterhaus JM, McKnight RA, Mueckler M, Devaskar SU, Moley KH.

Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7313-8.PMID: 10860996 [PubMed - indexed for MEDLINE]Related articlesFree article

The mechanism of insulin resistance caused by HIV protease inhibitor therapy.

Murata H, Hruz PW, Mueckler M.

J Biol Chem. 2000 Jul 7;275(27):20251-4.PMID: 10806189 [PubMed - indexed for MEDLINE]Related articlesFree article

Transgenic overexpression of hexokinase II in skeletal muscle does not increase glucose disposal in wild-type or Glut1-overexpressing mice.

Hansen PA, Marshall BA, Chen M, Holloszy JO, Mueckler M.

J Biol Chem. 2000 Jul 21;275(29):22381-6.PMID: 10764781 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel 68-kDa adipocyte protein phosphorylated on tyrosine in response to insulin and osmotic shock.

Hresko RC, Mueckler M.

J Biol Chem. 2000 Jun 16;275(24):18114-20.PMID: 10764780 [PubMed - indexed for MEDLINE]Related articlesFree article

Transgenic mice overexpressing GLUT-1 protein in muscle exhibit increased muscle glycogenesis after exercise.

Ren JM, Barucci N, Marshall BA, Hansen P, Mueckler MM, Shulman GI.

Am J Physiol Endocrinol Metab. 2000 Apr;278(4):E588-92.PMID: 10751190 [PubMed - indexed for MEDLINE]Related articlesFree article

Cysteine-scanning mutagenesis of transmembrane segment 7 of the GLUT1 glucose transporter.

Hruz PW, Mueckler MM.

J Biol Chem. 1999 Dec 17;274(51):36176-80.PMID: 10593902 [PubMed - indexed for MEDLINE]Related articlesFree article

ADP-ribosylation factor 6 (ARF6) defines two insulin-regulated secretory pathways in adipocytes.

Yang CZ, Mueckler M.

J Biol Chem. 1999 Sep 3;274(36):25297-300.PMID: 10464254 [PubMed - indexed for MEDLINE]Related articlesFree article

A conserved amino acid motif (R-X-G-R-R) in the Glut1 glucose transporter is an important determinant of membrane topology.

Sato M, Mueckler M.

J Biol Chem. 1999 Aug 27;274(35):24721-5.PMID: 10455140 [PubMed - indexed for MEDLINE]Related articlesFree article

Transmembrane segment 5 of the Glut1 glucose transporter is an amphipathic helix that forms part of the sugar permeation pathway.

Mueckler M, Makepeace C.

J Biol Chem. 1999 Apr 16;274(16):10923-6.PMID: 10196171 [PubMed - indexed for MEDLINE]Related articlesFree article

GLUT-1 or GLUT-4 transgenes in obese mice improve glucose tolerance but do not prevent insulin resistance.

Marshall BA, Hansen PA, Ensor NJ, Ogden MA, Mueckler M.

Am J Physiol. 1999 Feb;276(2 Pt 1):E390-400.PMID: 9950801 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperglycemia induces apoptosis in pre-implantation embryos through cell death effector pathways.

Moley KH, Chi MM, Knudson CM, Korsmeyer SJ, Mueckler MM.

Nat Med. 1998 Dec;4(12):1421-4. Erratum in: Nat Med 2002 Mar;8(3):303. PMID: 9846581 [PubMed - indexed for MEDLINE]Related articles

A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome).

Inoue H, Tanizawa Y, Wasson J, Behn P, Kalidas K, Bernal-Mizrachi E, Mueckler M, Marshall H, Donis-Keller H, Crock P, Rogers D, Mikuni M, Kumashiro H, Higashi K, Sobue G, Oka Y, Permutt MA.

Nat Genet. 1998 Oct;20(2):143-8.PMID: 9771706 [PubMed - indexed for MEDLINE]Related articles

A high fat diet impairs stimulation of glucose transport in muscle. Functional evaluation of potential mechanisms.

Hansen PA, Han DH, Marshall BA, Nolte LA, Chen MM, Mueckler M, Holloszy JO.

J Biol Chem. 1998 Oct 2;273(40):26157-63.PMID: 9748297 [PubMed - indexed for MEDLINE]Related articlesFree article

Testing the charge difference hypothesis for the assembly of a eucaryotic multispanning membrane protein.

Sato M, Hresko R, Mueckler M.

J Biol Chem. 1998 Sep 25;273(39):25203-8.PMID: 9737982 [PubMed - indexed for MEDLINE]Related articlesFree article

Maternal hyperglycemia alters glucose transport and utilization in mouse preimplantation embryos.

Moley KH, Chi MM, Mueckler MM.

Am J Physiol. 1998 Jul;275(1 Pt 1):E38-47.PMID: 9688872 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucosamine-induced insulin resistance in 3T3-L1 adipocytes is caused by depletion of intracellular ATP.

Hresko RC, Heimberg H, Chi MM, Mueckler M.

J Biol Chem. 1998 Aug 7;273(32):20658-68.PMID: 9685425 [PubMed - indexed for MEDLINE]Related articlesFree article

Dissociation of GLUT4 translocation and insulin-stimulated glucose transport in transgenic mice overexpressing GLUT1 in skeletal muscle.

Hansen PA, Wang W, Marshall BA, Holloszy JO, Mueckler M.

J Biol Chem. 1998 Jul 17;273(29):18173-9.PMID: 9660777 [PubMed - indexed for MEDLINE]Related articlesFree article

Subcellular distribution and differential expression of endogenous ADP-ribosylation factor 6 in mammalian cells.

Yang CZ, Heimberg H, D'Souza-Schorey C, Mueckler MM, Stahl PD.

J Biol Chem. 1998 Feb 13;273(7):4006-11.PMID: 9461590 [PubMed - indexed for MEDLINE]Related articlesFree article

Ligand-independent GLUT4 translocation induced by guanosine 5'-O-(3-thiotriphosphate) involves tyrosine phosphorylation.

Haruta T, Morris AJ, Vollenweider P, Nelson JG, Rose DW, Mueckler M, Olefsky JM.

Endocrinology. 1998 Jan;139(1):358-64.PMID: 9421434 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of an amino acid residue that lies between the exofacial vestibule and exofacial substrate-binding site of the Glut1 sugar permeation pathway.

Mueckler M, Makepeace C.

J Biol Chem. 1997 Nov 28;272(48):30141-6.PMID: 9374494 [PubMed - indexed for MEDLINE]Related articlesFree article

Structure, function and biosynthesis of GLUT1.

Mueckler M, Hresko RC, Sato M.

Biochem Soc Trans. 1997 Aug;25(3):951-4. Review. No abstract available. PMID: 9388579 [PubMed - indexed for MEDLINE]Related articles

Mapping novel pancreatic islet genes to human chromosomes.

Ferrer J, Wasson J, Schoor KD, Mueckler M, Donis-Keller H, Permutt MA.

Diabetes. 1997 Mar;46(3):386-92.PMID: 9032093 [PubMed - indexed for MEDLINE]Related articles

Insulin unmasks a COOH-terminal Glut4 epitope and increases glucose transport across T-tubules in skeletal muscle.

Wang W, Hansen PA, Marshall BA, Holloszy JO, Mueckler M.

J Cell Biol. 1996 Oct;135(2):415-30.PMID: 8896598 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effects of GLUT1 or GLUT4 overexpression on hexosamine biosynthesis by muscles of transgenic mice.

Buse MG, Robinson KA, Marshall BA, Mueckler M.

J Biol Chem. 1996 Sep 20;271(38):23197-202.PMID: 8798515 [PubMed - indexed for MEDLINE]Related articlesFree article