PubMed

Detecting outliers when fitting data with nonlinear regression - a new method based on robust nonlinear regression and the false discovery rate.

Motulsky HJ, Brown RE.

BMC Bioinformatics. 2006 Mar 9;7:123.PMID: 16526949 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of ketotifen on human lymphocytes in vitro and in vivo.

Petrasch S, van Tits LJ, Motulsky HJ, Brodde OE, Michel MC.

Arzneimittelforschung. 1993 Aug;43(8):904-8.PMID: 8216451 [PubMed - indexed for MEDLINE]Related articles

Does verapamil act as an immunomodulatory drug in vivo?

Maisel AS, Murray D, Polizzi S, Motulsky HJ, Brodde OE, van Tits LJ, Michel MC.

Immunopharmacology. 1991 Sep-Oct;22(2):85-91.PMID: 1761403 [PubMed - indexed for MEDLINE]Related articles

Cyclic AMP counteracts mitogen-induced inositol phosphate generation and increases in intracellular Ca2+ concentrations in human lymphocytes.

van Tits LJ, Michel MC, Motulsky HJ, Maisel AS, Brodde OE.

Br J Pharmacol. 1991 Jun;103(2):1288-94.PMID: 1653068 [PubMed - indexed for MEDLINE]Related articlesFree article

Stoichiometry of receptor-Gs-adenylate cyclase interactions.

Alousi AA, Jasper JR, Insel PA, Motulsky HJ.

FASEB J. 1991 Jun;5(9):2300-3.PMID: 1650314 [PubMed - indexed for MEDLINE]Related articlesFree article

PET receptors. Counting receptors using positron emission tomography.

Motulsky HJ.

Circulation. 1990 Oct;82(4):1536-8. No abstract available. PMID: 2169358 [PubMed - indexed for MEDLINE]Related articles

Distinction of NPY receptors in vitro and in vivo. I. NPY-(18-36) discriminates NPY receptor subtypes in vitro.

Michel MC, Schlicker E, Fink K, Boublik JH, Göthert M, Willette RN, Daly RN, Hieble JP, Rivier JE, Motulsky HJ.

Am J Physiol. 1990 Jul;259(1 Pt 1):E131-9.PMID: 2164786 [PubMed - indexed for MEDLINE]Related articles

Beta-adrenoceptor metabolism in wild-type, Gs, and protein kinase A-variant S49 cells.

Jasper JR, Motulsky HJ, Mahan LC, Insel PA.

Am J Physiol. 1990 Jul;259(1 Pt 1):C41-6.PMID: 1973600 [PubMed - indexed for MEDLINE]Related articles

Adrenergic control of circulating lymphocyte subpopulations. Effects of congestive heart failure, dynamic exercise, and terbutaline treatment.

Maisel AS, Knowlton KU, Fowler P, Rearden A, Ziegler MG, Motulsky HJ, Insel PA, Michel MC.

J Clin Invest. 1990 Feb;85(2):462-7.PMID: 2153706 [PubMed - indexed for MEDLINE]Related articlesFree article

Nonadrenergic [3H]idazoxan binding sites are physically distinct from alpha 2-adrenergic receptors.

Michel MC, Regan JW, Gerhardt MA, Neubig RR, Insel PA, Motulsky HJ.

Mol Pharmacol. 1990 Jan;37(1):65-8.PMID: 2153910 [PubMed - indexed for MEDLINE]Related articles

Lack of inotropic effects of neuropeptide Y in human myocardium.

Michel MC, Wirth SC, Zerkowski HR, Maisel AS, Motulsky HJ.

J Cardiovasc Pharmacol. 1989 Dec;14(6):919-22.PMID: 2481782 [PubMed - indexed for MEDLINE]Related articles

A new method for isolation of human lymphocyte subsets reveals differential regulation of beta-adrenergic receptors by terbutaline treatment.

Maisel AS, Fowler P, Rearden A, Motulsky HJ, Michel MC.

Clin Pharmacol Ther. 1989 Oct;46(4):429-39.PMID: 2551559 [PubMed - indexed for MEDLINE]Related articles

Defective signal transduction in T lymphocytes.

Michel MC, Maisel AS, Motulsky HJ.

N Engl J Med. 1989 Aug 17;321(7):475-6. No abstract available. PMID: 2788245 [PubMed - indexed for MEDLINE]Related articles

Calculating receptor number from binding experiments using same compound as radioligand and competitor.

DeBlasi A, O'Reilly K, Motulsky HJ.

Trends Pharmacol Sci. 1989 Jun;10(6):227-9.PMID: 2773043 [PubMed - indexed for MEDLINE]Related articles

Alpha 2-adrenergic receptor stimulation mobilizes intracellular Ca2+ in human erythroleukemia cells.

Michel MC, Brass LF, Williams A, Bokoch GM, LaMorte VJ, Motulsky HJ.

J Biol Chem. 1989 Mar 25;264(9):4986-91. Erratum in: J Biol Chem 1989 Oct 5;264(28):16963. PMID: 2564396 [PubMed - indexed for MEDLINE]Related articlesFree article

[3H]idazoxan and some other alpha 2-adrenergic drugs also bind with high affinity to a nonadrenergic site.

Michel MC, Brodde OE, Schnepel B, Behrendt J, Tschada R, Motulsky HJ, Insel PA.

Mol Pharmacol. 1989 Mar;35(3):324-30.PMID: 2564631 [PubMed - indexed for MEDLINE]Related articles

Tachyphylaxis with amrinone therapy: association with sequestration and down-regulation of lymphocyte beta-adrenergic receptors.

Maisel AS, Wright CM, Carter SM, Ziegler M, Motulsky HJ.

Ann Intern Med. 1989 Feb 1;110(3):195-201.PMID: 2536258 [PubMed - indexed for MEDLINE]Related articles

Elevation of plasma neuropeptide Y levels in congestive heart failure.

Maisel AS, Scott NA, Motulsky HJ, Michel MC, Boublik JH, Rivier JE, Ziegler M, Allen RS, Brown MR.

Am J Med. 1989 Jan;86(1):43-8.PMID: 2910096 [PubMed - indexed for MEDLINE]Related articles

Interaction between alpha 2-adrenergic and NPY receptor pathways in human erythroleukemia cells.

Motulsky HJ, Michel MC.

Clin Exp Hypertens A. 1989;11 Suppl 1:281-6.PMID: 2545382 [PubMed - indexed for MEDLINE]Related articles

Neuropeptide Y mobilizes Ca2+ and inhibits adenylate cyclase in human erythroleukemia cells.

Motulsky HJ, Michel MC.

Am J Physiol. 1988 Dec;255(6 Pt 1):E880-5.PMID: 3202164 [PubMed - indexed for MEDLINE]Related articles

In vivo regulation of beta-adrenergic receptors on mononuclear leukocytes and heart. Assessment of receptor compartmentation after agonist infusion and acute aortic constriction in guinea pigs.

Maisel AS, Ziegler MG, Carter S, Insel PA, Motulsky HJ.

J Clin Invest. 1988 Dec;82(6):2038-44.PMID: 2848867 [PubMed - indexed for MEDLINE]Related articlesFree article

The potency and kinetics of the beta-adrenergic receptors on human neutrophils.

Mueller H, Motulsky HJ, Sklar LA.

Mol Pharmacol. 1988 Sep;34(3):347-53.PMID: 2901665 [PubMed - indexed for MEDLINE]Related articles

Characterization of a bromoacetylated derivative of pindolol as a high affinity, irreversible beta adrenergic antagonist in cultured cells.

Jasper JR, Motulsky HJ, Insel PA.

J Pharmacol Exp Ther. 1988 Mar;244(3):820-4.PMID: 2908047 [PubMed - indexed for MEDLINE]Related articles

Fitting curves to data using nonlinear regression: a practical and nonmathematical review.

Motulsky HJ, Ransnas LA.

FASEB J. 1987 Nov;1(5):365-74. Review.PMID: 3315805 [PubMed - indexed for MEDLINE]Related articlesFree article

Ischemia- and agonist-induced changes in alpha- and beta-adrenergic receptor traffic in guinea pig hearts.

Maisel AS, Motulsky HJ, Ziegler MG, Insel PA.

Am J Physiol. 1987 Nov;253(5 Pt 2):H1159-66.PMID: 2825544 [PubMed - indexed for MEDLINE]Related articles

Compartmentation of alpha 2-adrenergic receptors in human erythroleukemia (HEL) cells.

McKernan RM, Howard MJ, Motulsky HJ, Insel PA.

Mol Pharmacol. 1987 Aug;32(1):258-65.PMID: 3039340 [PubMed - indexed for MEDLINE]Related articles

Interactions of amiloride with alpha- and beta-adrenergic receptors: amiloride reveals an allosteric site on alpha 2-adrenergic receptors.

Howard MJ, Hughes RJ, Motulsky HJ, Mullen MD, Insel PA.

Mol Pharmacol. 1987 Jul;32(1):53-8.PMID: 3037303 [PubMed - indexed for MEDLINE]Related articles

Receptor redistribution does not accompany terbutaline-induced down regulation of beta-adrenergic receptors on human mononuclear leukocytes.

Maisel AS, Motulsky HJ.

Clin Pharmacol Ther. 1987 Jul;42(1):100-6.PMID: 3036413 [PubMed - indexed for MEDLINE]Related articles

Propranolol treatment externalizes beta-adrenergic receptors in guinea pig myocardium and prevents further externalization by ischemia.

Maisel AS, Motulsky HJ, Insel PA.

Circ Res. 1987 Jan;60(1):108-12.PMID: 3032472 [PubMed - indexed for MEDLINE]Related articlesFree article

Life cycles of cardiac alpha 1- and beta-adrenergic receptors.

Maisel AS, Motulsky HJ, Insel PA.

Biochem Pharmacol. 1987 Jan 1;36(1):1-6. Review. No abstract available. PMID: 3026400 [PubMed - indexed for MEDLINE]Related articles

Expression of fibrinogen receptors during activation and subsequent desensitization of human platelets by epinephrine.

Shattil SJ, Motulsky HJ, Insel PA, Flaherty L, Brass LF.

Blood. 1986 Dec;68(6):1224-31.PMID: 3779100 [PubMed - indexed for MEDLINE]Related articlesFree article

Transient catecholamine modulation of neutrophil activation: kinetic and intracellular aspects of isoproterenol action.

Tecoma ES, Motulsky HJ, Traynor AE, Omann GM, Muller H, Sklar LA.

J Leukoc Biol. 1986 Nov;40(5):629-44.PMID: 3021883 [PubMed - indexed for MEDLINE]Related articlesFree article

Temperature-dependent binding of hydrophilic beta-adrenergic receptor ligands to intact human lymphocytes.

Thede-Reynolds KR, Motulsky HJ, Feldman RD.

Life Sci. 1986 Oct 13;39(15):1325-34.PMID: 2876367 [PubMed - indexed for MEDLINE]Related articles

In vivo regulation of beta-adrenergic receptors on human mononuclear leukocytes: assessment of receptor number, location, and function after posture change, exercise, and isoproterenol infusion.

DeBlasi A, Maisel AS, Feldman RD, Ziegler MG, Fratelli M, DiLallo M, Smith DA, Lai CY, Motulsky HJ.

J Clin Endocrinol Metab. 1986 Oct;63(4):847-53.PMID: 3018026 [PubMed - indexed for MEDLINE]Related articles

Desensitization and redistribution of beta-adrenergic receptors on human mononuclear leukocytes.

Motulsky HJ, Cunningham EM, DeBlasi A, Insel PA.

Am J Physiol. 1986 May;250(5 Pt 1):E583-90.PMID: 3010734 [PubMed - indexed for MEDLINE]Related articles

Regulation of hormone-stimulated cyclic AMP accumulation in intact human mononuclear leukocytes by blood plasma.

Motulsky HJ, Smith D, Terman BI, Feldman R.

J Cyclic Nucleotide Protein Phosphor Res. 1986;11(5):329-43.PMID: 3040817 [PubMed - indexed for MEDLINE]Related articles

Desensitization of epinephrine-initiated platelet aggregation does not alter binding to the alpha 2-adrenergic receptor or receptor coupling to adenylate cyclase.

Motulsky HJ, Shattil SJ, Ferry N, Rozansky D, Insel PA.

Mol Pharmacol. 1986 Jan;29(1):1-6.PMID: 2418346 [PubMed - indexed for MEDLINE]Related articles

Agonist-induced redistribution of beta-adrenergic receptors on intact human mononuclear leukocytes: redistributed receptors are nonfunctional.

De Blasi A, Lipartiti M, Motulsky HJ, Insel PA, Fratelli M.

J Clin Endocrinol Metab. 1985 Dec;61(6):1081-8.PMID: 2865270 [PubMed - indexed for MEDLINE]Related articles

Externalization of beta-adrenergic receptors promoted by myocardial ischemia.

Maisel AS, Motulsky HJ, Insel PA.

Science. 1985 Oct 11;230(4722):183-6.PMID: 2994229 [PubMed - indexed for MEDLINE]Related articles

Do agonists promote rapid internalization of beta-adrenergic receptors?

Mahan LC, Motulsky HJ, Insel PA.

Proc Natl Acad Sci U S A. 1985 Oct;82(19):6566-70.PMID: 2864689 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of cyclic AMP accumulation in lymphoid cells.

Insel PA, Motulsky HJ, Mahan LC.

Proc Soc Exp Biol Med. 1985 Sep;179(4):472-8.PMID: 2991940 [PubMed - indexed for MEDLINE]Related articles

Episodic catatonia, hypertension, and tachycardia: elevated plasma catecholamines.

Wheeler AH, Ziegler MG, Insel PA, Motulsky HJ.

Neurology. 1985 Jul;35(7):1053-5.PMID: 4010946 [PubMed - indexed for MEDLINE]Related articles

Effects of Na+ on the muscarinic cholinergic receptor of rat ventricular myocytes.

Buxton IL, Rozansky D, Brunton LL, Motulsky HJ.

J Cardiovasc Pharmacol. 1985 May-Jun;7(3):476-81.PMID: 2410677 [PubMed - indexed for MEDLINE]Related articles

Hypotension after quinidine plus verapamil. Possible additive competition at alpha-adrenergic receptors.

Maisel AS, Motulsky HJ, Insel PA.

N Engl J Med. 1985 Jan 17;312(3):167-70. No abstract available. PMID: 2981405 [PubMed - indexed for MEDLINE]Related articles

Quinidine is a competitive antagonist at alpha 1- and alpha 2-adrenergic receptors.

Motulsky HJ, Maisel AS, Snavely MD, Insel PA.

Circ Res. 1984 Sep;55(3):376-81.PMID: 6147208 [PubMed - indexed for MEDLINE]Related articlesFree article

A hypothesis linking intracellular sodium, membrane receptors, and hypertension.

Insel PA, Motulsky HJ.

Life Sci. 1984 Mar 12;34(11):1009-13.PMID: 6321865 [PubMed - indexed for MEDLINE]Related articles

The kinetics of competitive radioligand binding predicted by the law of mass action.

Motulsky HJ, Mahan LC.

Mol Pharmacol. 1984 Jan;25(1):1-9.PMID: 6708928 [PubMed - indexed for MEDLINE]Related articles

ADP- and epinephrine-elicited release of [3H]guanylylimidodiphosphate from platelet membranes. Implications for receptor-Ni stoichiometry.

Motulsky HJ, Insel PA.

FEBS Lett. 1983 Nov 28;164(1):13-6.PMID: 6653777 [PubMed - indexed for MEDLINE]Related articles

Time-dependent decreases in binding affinity of agonists for beta-adrenergic receptors of intact S49 lymphoma cells. A mechanism of desensitization.

Insel PA, Mahan LC, Motulsky HJ, Stoolman LM, Koachman AM.

J Biol Chem. 1983 Nov 25;258(22):13597-605.PMID: 6315705 [PubMed - indexed for MEDLINE]Related articlesFree article

Calcium-channel-blocking agents.

Insel PA, Motulsky HJ.

N Engl J Med. 1983 Jun 2;308(22):1361-2. No abstract available. PMID: 6302509 [PubMed - indexed for MEDLINE]Related articles