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    Results: 1 to 50 of 109

    1.

    The Deletion Variant of Nicotinamide Nucleotide Transhydrogenase (Nnt) Does Not Affect Insulin Secretion or Glucose Tolerance.

    Wong N, Blair AR, Morahan G, Andrikopoulos S.

    Endocrinology. 2009 Nov 11. [Epub ahead of print]PMID: 19906813 [PubMed - as supplied by publisher]Related articles

    2.

    Quantification of Insulin Gene Expression During Development of Pancreatic Islet Cells.

    Jiang FX, Mehta M, Morahan G.

    Pancreas. 2009 Oct 2. [Epub ahead of print]PMID: 19812524 [PubMed - as supplied by publisher]Related articles

    3.

    Rescue of skeletal muscle alpha-actin-null mice by cardiac (fetal) alpha-actin.

    Nowak KJ, Ravenscroft G, Jackaman C, Filipovska A, Davies SM, Lim EM, Squire SE, Potter AC, Baker E, Clément S, Sewry CA, Fabian V, Crawford K, Lessard JL, Griffiths LM, Papadimitriou JM, Shen Y, Morahan G, Bakker AJ, Davies KE, Laing NG.

    J Cell Biol. 2009 Jun 1;185(5):903-15. Epub 2009 May 25.PMID: 19468071 [PubMed - indexed for MEDLINE]Related articles

    4.

    Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.

    Barrett JC, Clayton DG, Concannon P, Akolkar B, Cooper JD, Erlich HA, Julier C, Morahan G, Nerup J, Nierras C, Plagnol V, Pociot F, Schuilenburg H, Smyth DJ, Stevens H, Todd JA, Walker NM, Rich SS; The Type 1 Diabetes Genetics Consortium.

    Nat Genet. 2009 May 10. [Epub ahead of print]PMID: 19430480 [PubMed - as supplied by publisher]Related articles

    5.

    Potential of small molecule protein tyrosine kinase inhibitors as immuno-modulators and inhibitors of the development of type 1 diabetes.

    Little PJ, Cohen N, Morahan G.

    ScientificWorldJournal. 2009 Mar 31;9:224-8. No abstract available. PMID: 19347233 [PubMed - indexed for MEDLINE]Related articles

    6.

    Results of the MHC fine mapping workshop.

    Rich SS, Akolkar B, Concannon P, Erlich H, Hilner J, Julier C, Morahan G, Nerup J, Nierras C, Pociot F, Todd JA.

    Diabetes Obes Metab. 2009 Feb;11 Suppl 1:108-9. No abstract available. PMID: 19143823 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Missingness in the T1DGC MHC fine-mapping SNP data: association with HLA genotype and potential influence on genetic association studies.

    James I, McKinnon E, Gaudieri S, Morahan G; Diabetes Genetics Consortium.

    Diabetes Obes Metab. 2009 Feb;11 Suppl 1:101-7.PMID: 19143822 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Association of MHC SNP genotype with susceptibility to type 1 diabetes: a modified survival approach.

    McKinnon E, Morahan G, Nolan D, James I; Diabetes Genetics Consortium.

    Diabetes Obes Metab. 2009 Feb;11 Suppl 1:92-100.PMID: 19143821 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Effect of linkage status of affected sib-pairs on the search for novel type 1 diabetes susceptibility genes in the HLA complex.

    Morahan G, Mehta M, McKinnon E, James I; Diabetes Genetics Consortium.

    Diabetes Obes Metab. 2009 Feb;11 Suppl 1:67-73.PMID: 19143817 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Genome-wide scan for linkage to type 1 diabetes in 2,496 multiplex families from the Type 1 Diabetes Genetics Consortium.

    Concannon P, Chen WM, Julier C, Morahan G, Akolkar B, Erlich HA, Hilner JE, Nerup J, Nierras C, Pociot F, Todd JA, Rich SS; Type 1 Diabetes Genetics Consortium.

    Diabetes. 2009 Apr;58(4):1018-22. Epub 2009 Jan 9.PMID: 19136655 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Establishment of "The Gene Mine": a resource for rapid identification of complex trait genes.

    Morahan G, Balmer L, Monley D.

    Mamm Genome. 2008 Jun;19(6):390-3. Epub 2008 Aug 21.PMID: 18716834 [PubMed - indexed for MEDLINE]Related articles

    12.

    A human type 1 diabetes susceptibility locus maps to chromosome 21q22.3.

    Concannon P, Onengut-Gumuscu S, Todd JA, Smyth DJ, Pociot F, Bergholdt R, Akolkar B, Erlich HA, Hilner JE, Julier C, Morahan G, Nerup J, Nierras CR, Chen WM, Rich SS; Type 1 Diabetes Genetics Consortium.

    Diabetes. 2008 Oct;57(10):2858-61. Epub 2008 Jul 22.PMID: 18647951 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    The clinical course of steroid-sensitive childhood nephrotic syndrome is associated with a functional IL12B promoter polymorphism.

    Müller-Berghaus J, Kemper MJ, Hoppe B, Querfeld U, Müller-Wiefel DE, Morahan G, Schadendorf D, Tenbrock K.

    Nephrol Dial Transplant. 2008 Dec;23(12):3841-4. Epub 2008 Jul 15.PMID: 18632587 [PubMed - indexed for MEDLINE]Related articles

    14.

    Type 1 diabetes: lessons for other autoimmune diseases?

    Harrison LC, Honeyman MC, Morahan G, Wentworth JM, Elkassaby S, Colman PG, Fourlanos S.

    J Autoimmun. 2008 Nov;31(3):306-10. Epub 2008 Jun 16.PMID: 18558477 [PubMed - indexed for MEDLINE]Related articles

    15.

    Systems genetics can provide new insights in to immune regulation and autoimmunity.

    Morahan G, Peeva V, Mehta M, Williams R.

    J Autoimmun. 2008 Nov;31(3):233-6. Epub 2008 Jun 3.PMID: 18511236 [PubMed - indexed for MEDLINE]Related articles

    16.

    The rising incidence of type 1 diabetes is accounted for by cases with lower-risk human leukocyte antigen genotypes.

    Fourlanos S, Varney MD, Tait BD, Morahan G, Honeyman MC, Colman PG, Harrison LC.

    Diabetes Care. 2008 Aug;31(8):1546-9. Epub 2008 May 16.PMID: 18487476 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Too much of a good thing: why it is bad to stimulate the beta cell to secrete insulin.

    Aston-Mourney K, Proietto J, Morahan G, Andrikopoulos S.

    Diabetologia. 2008 Apr;51(4):540-5. Epub 2008 Feb 2.PMID: 18246324 [PubMed - indexed for MEDLINE]Related articles

    18.

    Identification of Plet-1 as a specific marker of early thymic epithelial progenitor cells.

    Depreter MG, Blair NF, Gaskell TL, Nowell CS, Davern K, Pagliocca A, Stenhouse FH, Farley AM, Fraser A, Vrana J, Robertson K, Morahan G, Tomlinson SR, Blackburn CC.

    Proc Natl Acad Sci U S A. 2008 Jan 22;105(3):961-6. Epub 2008 Jan 14.PMID: 18195351 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Increased nicotinamide nucleotide transhydrogenase levels predispose to insulin hypersecretion in a mouse strain susceptible to diabetes.

    Aston-Mourney K, Wong N, Kebede M, Zraika S, Balmer L, McMahon JM, Fam BC, Favaloro J, Proietto J, Morahan G, Andrikopoulos S.

    Diabetologia. 2007 Dec;50(12):2476-85. Epub 2007 Oct 6.PMID: 17922105 [PubMed - indexed for MEDLINE]Related articles

    20.

    Systems genetics: the next generation in genetics research?

    Morahan G, Williams RW.

    Novartis Found Symp. 2007;281:181-8; discussion 188-91, 208-9. Review. No abstract available. PMID: 17534074 [PubMed - indexed for MEDLINE]Related articles

    21.

    Association of variants in the IL12B gene with leprosy and tuberculosis.

    Morahan G, Kaur G, Singh M, Rapthap CC, Kumar N, Katoch K, Mehra NK, Huang D.

    Tissue Antigens. 2007 Apr;69 Suppl 1:234-6.PMID: 17445208 [PubMed - indexed for MEDLINE]Related articles

    22.

    Mapping of QTLs for oral alcohol self-administration in B6.C and B6.I quasi-congenic RQI strains.

    Vadasz C, Saito M, Gyetvai BM, Oros M, Szakall I, Kovacs KM, Prasad VV, Morahan G, Toth R.

    Neurochem Res. 2007 Jul;32(7):1099-112. Epub 2007 Feb 2.PMID: 17273929 [PubMed - indexed for MEDLINE]Related articlesFree article

    23.

    Ventral tegmental transcriptome response to intermittent nicotine treatment and withdrawal in BALB/cJ, C57BL/6ByJ, and quasi-congenic RQI mice.

    Vadasz C, Saito M, O'Brien D, Zavadil J, Morahan G, Chakraborty G, Wang R.

    Neurochem Res. 2007 Mar;32(3):457-80.PMID: 17268848 [PubMed - indexed for MEDLINE]Related articles

    24.

    The Type 1 Diabetes Genetics Consortium.

    Rich SS, Concannon P, Erlich H, Julier C, Morahan G, Nerup J, Pociot F, Todd JA.

    Ann N Y Acad Sci. 2006 Oct;1079:1-8. Review.PMID: 17130525 [PubMed - indexed for MEDLINE]Related articles

    25.

    Proinsulin is encoded by an RNA splice variant in human blood myeloid cells.

    Narendran P, Neale AM, Lee BH, Ngui K, Steptoe RJ, Morahan G, Madsen O, Dromey JA, Jensen KP, Harrison LC.

    Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16430-5. Epub 2006 Oct 19.PMID: 17053071 [PubMed - indexed for MEDLINE]Related articlesFree article

    26.

    IL10 and IL12B polymorphisms each influence IL-12p70 secretion by dendritic cells in response to LPS.

    Peng JC, Abu Bakar S, Richardson MM, Jonsson JJ, Frazer IH, Nielsen LK, Morahan G, Thomas R.

    Immunol Cell Biol. 2006 Apr;84(2):227-32.PMID: 16519741 [PubMed - indexed for MEDLINE]Related articles

    27.

    Localization of Idd11 is not associated with thymus and nkt cell abnormalities in NOD mice.

    Brodnicki TC, Fletcher AL, Pellicci DG, Berzins SP, McClive P, Quirk F, Webster KE, Scott HS, Boyd RL, Godfrey DI, Morahan G.

    Diabetes. 2005 Dec;54(12):3453-7.PMID: 16306361 [PubMed - indexed for MEDLINE]Related articlesFree article

    28.

    Type 1 diabetes: evidence for susceptibility loci from four genome-wide linkage scans in 1,435 multiplex families.

    Concannon P, Erlich HA, Julier C, Morahan G, Nerup J, Pociot F, Todd JA, Rich SS; Type 1 Diabetes Genetics Consortium.

    Diabetes. 2005 Oct;54(10):2995-3001.PMID: 16186404 [PubMed - indexed for MEDLINE]Related articlesFree article

    29.

    Diabetes induces Na/H exchange activity and hypertrophy of rat mesenteric but not basilar arteries.

    Dilley RJ, Farrelly CA, Allen TJ, Jandeleit-Dahm K, Cooper ME, Morahan G, Little PJ.

    Diabetes Res Clin Pract. 2005 Dec;70(3):201-8. Epub 2005 Jun 8.PMID: 15949863 [PubMed - indexed for MEDLINE]Related articles

    30.

    Fms-like tyrosine kinase 3 ligand administration overcomes a genetically determined dendritic cell deficiency in NOD mice and protects against diabetes development.

    O'Keeffe M, Brodnicki TC, Fancke B, Vremec D, Morahan G, Maraskovsky E, Steptoe R, Harrison LC, Shortman K.

    Int Immunol. 2005 Mar;17(3):307-14. Epub 2005 Jan 31.PMID: 15684037 [PubMed - indexed for MEDLINE]Related articlesFree article

    31.

    Insulin expressing hepatocytes not destroyed in transgenic NOD mice.

    Tabiin MT, White CP, Morahan G, Tuch BE.

    J Autoimmune Dis. 2004 Nov 8;1(1):3.PMID: 15679918 [PubMed - as supplied by publisher]Related articlesFree article

    32.

    Alleles of the IL12B 3'UTR associate with late onset of type 1 diabetes.

    Windsor L, Morahan G, Huang D, McCann V, Jones T, James I, Christiansen FT, Price P.

    Hum Immunol. 2004 Dec;65(12):1432-6.PMID: 15603869 [PubMed - indexed for MEDLINE]Related articles

    33.

    The Collaborative Cross, a community resource for the genetic analysis of complex traits.

    Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD, Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ, Buckler E, Burmeister M, Chesler EJ, Cheverud JM, Clapcote S, Cook MN, Cox RD, Crabbe JC, Crusio WE, Darvasi A, Deschepper CF, Doerge RW, Farber CR, Forejt J, Gaile D, Garlow SJ, Geiger H, Gershenfeld H, Gordon T, Gu J, Gu W, de Haan G, Hayes NL, Heller C, Himmelbauer H, Hitzemann R, Hunter K, Hsu HC, Iraqi FA, Ivandic B, Jacob HJ, Jansen RC, Jepsen KJ, Johnson DK, Johnson TE, Kempermann G, Kendziorski C, Kotb M, Kooy RF, Llamas B, Lammert F, Lassalle JM, Lowenstein PR, Lu L, Lusis A, Manly KF, Marcucio R, Matthews D, Medrano JF, Miller DR, Mittleman G, Mock BA, Mogil JS, Montagutelli X, Morahan G, Morris DG, Mott R, Nadeau JH, Nagase H, Nowakowski RS, O'Hara BF, Osadchuk AV, Page GP, Paigen B, Paigen K, Palmer AA, Pan HJ, Peltonen-Palotie L, Peirce J, Pomp D, Pravenec M, Prows DR, Qi Z, Reeves RH, Roder J, Rosen GD, Schadt EE, Schalkwyk LC, Seltzer Z, Shimomura K, Shou S, Sillanpää MJ, Siracusa LD, Snoeck HW, Spearow JL, Svenson K, Tarantino LM, Threadgill D, Toth LA, Valdar W, de Villena FP, Warden C, Whatley S, Williams RW, Wiltshire T, Yi N, Zhang D, Zhang M, Zou F; Complex Trait Consortium.

    Nat Genet. 2004 Nov;36(11):1133-7.PMID: 15514660 [PubMed - indexed for MEDLINE]Related articles

    34.

    Deficient IL-12p70 secretion by dendritic cells based on IL12B promoter genotype.

    Müller-Berghaus J, Kern K, Paschen A, Nguyen XD, Klüter H, Morahan G, Schadendorf D.

    Genes Immun. 2004 Aug;5(5):431-4.PMID: 15175646 [PubMed - indexed for MEDLINE]Related articles

    35.

    Persistence of recipient lymphocytes in NOD mice after irradiation and bone marrow transplantation.

    Steptoe RJ, Stankovic S, Lopaticki S, Jones LK, Harrison LC, Morahan G.

    J Autoimmun. 2004 Mar;22(2):131-8.PMID: 14987741 [PubMed - indexed for MEDLINE]Related articles

    36.

    The nature and identification of quantitative trait loci: a community's view.

    Abiola O, Angel JM, Avner P, Bachmanov AA, Belknap JK, Bennett B, Blankenhorn EP, Blizard DA, Bolivar V, Brockmann GA, Buck KJ, Bureau JF, Casley WL, Chesler EJ, Cheverud JM, Churchill GA, Cook M, Crabbe JC, Crusio WE, Darvasi A, de Haan G, Dermant P, Doerge RW, Elliot RW, Farber CR, Flaherty L, Flint J, Gershenfeld H, Gibson JP, Gu J, Gu W, Himmelbauer H, Hitzemann R, Hsu HC, Hunter K, Iraqi FF, Jansen RC, Johnson TE, Jones BC, Kempermann G, Lammert F, Lu L, Manly KF, Matthews DB, Medrano JF, Mehrabian M, Mittlemann G, Mock BA, Mogil JS, Montagutelli X, Morahan G, Mountz JD, Nagase H, Nowakowski RS, O'Hara BF, Osadchuk AV, Paigen B, Palmer AA, Peirce JL, Pomp D, Rosemann M, Rosen GD, Schalkwyk LC, Seltzer Z, Settle S, Shimomura K, Shou S, Sikela JM, Siracusa LD, Spearow JL, Teuscher C, Threadgill DW, Toth LA, Toye AA, Vadasz C, Van Zant G, Wakeland E, Williams RW, Zhang HG, Zou F; Complex Trait Consortium.

    Nat Rev Genet. 2003 Nov;4(11):911-6. Review.PMID: 14634638 [PubMed - indexed for MEDLINE]Related articlesFree article

    37.

    Plasma interleukin-12 in malaria-tolerant papua new guineans: inverse correlation with Plasmodium falciparum parasitemia and peripheral blood mononuclear cell nitric oxide synthase activity.

    Boutlis CS, Lagog M, Chaisavaneeyakorn S, Misukonis MA, Bockarie MJ, Mgone CS, Wang Z, Morahan G, Weinberg JB, Udhayakumar V, Anstey NM.

    Infect Immun. 2003 Nov;71(11):6354-7.PMID: 14573655 [PubMed - indexed for MEDLINE]Related articlesFree article

    38.

    Identification of a T1D susceptibility gene.

    Morahan G.

    ScientificWorldJournal. 2001 May 1;1:198-9. Review.PMID: 12805669 [PubMed - indexed for MEDLINE]Related articles

    40.

    HLA genes associated with autoimmunity and progression to disease in type 1 diabetes.

    Tait BD, Colman PG, Morahan G, Marchinovska L, Dore E, Gellert S, Honeyman MC, Stephen K, Loth A.

    Tissue Antigens. 2003 Feb;61(2):146-53.PMID: 12694582 [PubMed - indexed for MEDLINE]Related articles

    41.

    A susceptibility allele from a non-diabetes-prone mouse strain accelerates diabetes in NOD congenic mice.

    Brodnicki TC, Quirk F, Morahan G.

    Diabetes. 2003 Jan;52(1):218-22.PMID: 12502517 [PubMed - indexed for MEDLINE]Related articlesFree article

    42.

    A promoter polymorphism in the gene encoding interleukin-12 p40 (IL12B) is associated with mortality from cerebral malaria and with reduced nitric oxide production.

    Morahan G, Boutlis CS, Huang D, Pain A, Saunders JR, Hobbs MR, Granger DL, Weinberg JB, Peshu N, Mwaikambo ED, Marsh K, Roberts DJ, Anstey NM.

    Genes Immun. 2002 Nov;3(7):414-8.PMID: 12424623 [PubMed - indexed for MEDLINE]Related articlesFree article

    43.

    Genetics of autoimmune diseases in humans and in animal models.

    Morahan G, Morel L.

    Curr Opin Immunol. 2002 Dec;14(6):803-11. Review.PMID: 12413533 [PubMed - indexed for MEDLINE]Related articles

    44.

    Polymorphisms in cytokine genes define subpopulations of HIV-1 patients who experienced immune restoration diseases.

    Price P, Morahan G, Huang D, Stone E, Cheong KY, Castley A, Rodgers M, McIntyre MQ, Abraham LJ, French MA.

    AIDS. 2002 Oct 18;16(15):2043-7.PMID: 12370503 [PubMed - indexed for MEDLINE]Related articles

    45.

    Association of IL12B promoter polymorphism with severity of atopic and non-atopic asthma in children.

    Morahan G, Huang D, Wu M, Holt BJ, White GP, Kendall GE, Sly PD, Holt PG.

    Lancet. 2002 Aug 10;360(9331):455-9. Erratum in: Lancet 2002 Dec 7;360(9348):1892. PMID: 12241719 [PubMed - indexed for MEDLINE]Related articles

    46.

    Polymorphisms in the Il12b gene affect structure and expression of IL-12 in NOD and other autoimmune-prone mouse strains.

    Ymer SI, Huang D, Penna G, Gregori S, Branson K, Adorini L, Morahan G.

    Genes Immun. 2002 May;3(3):151-7.PMID: 12070779 [PubMed - indexed for MEDLINE]Related articlesFree article

    47.

    A locus affecting immunoglobulin isotype selection (Igis1) maps to the MHC region in C57BL, BALB/c and NOD mice.

    Matthews VB, Morahan G, Price P.

    Immunol Cell Biol. 2001 Dec;79(6):576-82.PMID: 11903616 [PubMed - indexed for MEDLINE]Related articlesFree article

    48.

    Effect of localized cytokine dysregulation: accelerated rejection of IL-2-expressing skin grafts.

    Blackburn C, Grogan JL, Augustine CL, Miller JF, Varigos G, Morahan G.

    Immunol Cell Biol. 2001 Apr;79(2):128-31.PMID: 11264705 [PubMed - indexed for MEDLINE]Related articlesFree article

    50.

    Linkage disequilibrium of a type 1 diabetes susceptibility locus with a regulatory IL12B allele.

    Morahan G, Huang D, Ymer SI, Cancilla MR, Stephen K, Dabadghao P, Werther G, Tait BD, Harrison LC, Colman PG.

    Nat Genet. 2001 Feb;27(2):218-21. Erratum in: Nat Genet 2001 Mar;27(3):346. PMID: 11175794 [PubMed - indexed for MEDLINE]Related articles

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