PubMed

Rho directs widespread termination of intragenic and stable RNA transcription.

Peters JM, Mooney RA, Kuan PF, Rowland JL, Keles S, Landick R.

Proc Natl Acad Sci U S A. 2009 Sep 8;106(36):15406-11. Epub 2009 Aug 20.PMID: 19706412 [PubMed - in process]Related articles

Loss of Kupffer cells in diet-induced obesity is associated with increased hepatic steatosis, STAT3 signaling, and further decreases in insulin signaling.

Clementi AH, Gaudy AM, van Rooijen N, Pierce RH, Mooney RA.

Biochim Biophys Acta. 2009 Nov;1792(11):1062-72. Epub 2009 Aug 20.PMID: 19699298 [PubMed - in process]Related articles

Two structurally independent domains of E. coli NusG create regulatory plasticity via distinct interactions with RNA polymerase and regulators.

Mooney RA, Schweimer K, Rösch P, Gottesman M, Landick R.

J Mol Biol. 2009 Aug 14;391(2):341-58. Epub 2009 Jun 3.PMID: 19500594 [PubMed - indexed for MEDLINE]Related articles

Regulator trafficking on bacterial transcription units in vivo.

Mooney RA, Davis SE, Peters JM, Rowland JL, Ansari AZ, Landick R.

Mol Cell. 2009 Jan 16;33(1):97-108.PMID: 19150431 [PubMed - indexed for MEDLINE]Related articles

Functional specialization of transcription elongation factors.

Belogurov GA, Mooney RA, Svetlov V, Landick R, Artsimovitch I.

EMBO J. 2009 Jan 21;28(2):112-22. Epub 2008 Dec 18.PMID: 19096362 [PubMed - indexed for MEDLINE]Related articles

Maternal serum alpha-fetoprotein values in type 1 and type 2 diabetic patients.

Thornburg LL, Knight KM, Peterson CJ, McCall KB, Mooney RA, Pressman EK.

Am J Obstet Gynecol. 2008 Aug;199(2):135.e1-5. Epub 2008 May 2.PMID: 18455133 [PubMed - indexed for MEDLINE]Related articles

Rapid isolation and identification of bacteriophage T4-encoded modifications of Escherichia coli RNA polymerase: a generic method to study bacteriophage/host interactions.

Westblade LF, Minakhin L, Kuznedelov K, Tackett AJ, Chang EJ, Mooney RA, Vvedenskaya I, Wang QJ, Fenyö D, Rout MP, Landick R, Chait BT, Severinov K, Darst SA.

J Proteome Res. 2008 Mar;7(3):1244-50. Epub 2008 Feb 14.PMID: 18271525 [PubMed - indexed for MEDLINE]Related articlesFree article

Counterpoint: Interleukin-6 does not have a beneficial role in insulin sensitivity and glucose homeostasis.

Mooney RA.

J Appl Physiol. 2007 Feb;102(2):816-8; discussion 818-9. No abstract available. PMID: 17284655 [PubMed - indexed for MEDLINE]Related articles

Altered glucose homeostasis in mice lacking the receptor protein tyrosine phosphatase sigma.

Chagnon MJ, Elchebly M, Uetani N, Dombrowski L, Cheng A, Mooney RA, Marette A, Tremblay ML.

Can J Physiol Pharmacol. 2006 Jul;84(7):755-63.PMID: 16998539 [PubMed - indexed for MEDLINE]Related articles

Sequence-resolved detection of pausing by single RNA polymerase molecules.

Herbert KM, La Porta A, Wong BJ, Mooney RA, Neuman KC, Landick R, Block SM.

Cell. 2006 Jun 16;125(6):1083-94.PMID: 16777599 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional interplay between the jaw domain of bacterial RNA polymerase and allele-specific residues in the product RNA-binding pocket.

Ederth J, Mooney RA, Isaksson LA, Landick R.

J Mol Biol. 2006 Mar 10;356(5):1163-79. Epub 2005 Dec 13.PMID: 16405998 [PubMed - indexed for MEDLINE]Related articles

Sigma and RNA polymerase: an on-again, off-again relationship?

Mooney RA, Darst SA, Landick R.

Mol Cell. 2005 Nov 11;20(3):335-45. Review.PMID: 16285916 [PubMed - indexed for MEDLINE]Related articles

Interleukin-6 depletion selectively improves hepatic insulin action in obesity.

Klover PJ, Clementi AH, Mooney RA.

Endocrinology. 2005 Aug;146(8):3417-27. Epub 2005 Apr 21.PMID: 15845623 [PubMed - indexed for MEDLINE]Related articlesFree article

A hydrophobic patch on the flap-tip helix of E.coli RNA polymerase mediates sigma(70) region 4 function.

Geszvain K, Gruber TM, Mooney RA, Gross CA, Landick R.

J Mol Biol. 2004 Oct 22;343(3):569-87.PMID: 15465046 [PubMed - indexed for MEDLINE]Related articles

New developments in prenatal screening for Down syndrome.

Baliff JP, Mooney RA.

Am J Clin Pathol. 2003 Dec;120 Suppl:S14-24. Review.PMID: 15298140 [PubMed - indexed for MEDLINE]Related articles

EGF-dependent cell cycle progression is controlled by density-dependent regulation of Akt activation.

LeVea CM, Reeder JE, Mooney RA.

Exp Cell Res. 2004 Jul 1;297(1):272-84.PMID: 15194442 [PubMed - indexed for MEDLINE]Related articles

Hepatocytes: critical for glucose homeostasis.

Klover PJ, Mooney RA.

Int J Biochem Cell Biol. 2004 May;36(5):753-8. Review.PMID: 15061128 [PubMed - indexed for MEDLINE]Related articles

Tethering sigma70 to RNA polymerase reveals high in vivo activity of sigma factors and sigma70-dependent pausing at promoter-distal locations.

Mooney RA, Landick R.

Genes Dev. 2003 Nov 15;17(22):2839-51.PMID: 14630944 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice.

Klover PJ, Zimmers TA, Koniaris LG, Mooney RA.

Diabetes. 2003 Nov;52(11):2784-9.PMID: 14578297 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma amino acids profiles in children with autism: potential risk of nutritional deficiencies.

Arnold GL, Hyman SL, Mooney RA, Kirby RS.

J Autism Dev Disord. 2003 Aug;33(4):449-54.PMID: 12959424 [PubMed - indexed for MEDLINE]Related articles

Second-trimester maternal serum placental growth factor and vascular endothelial growth factor for predicting severe, early-onset preeclampsia.

Polliotti BM, Fry AG, Saller DN, Mooney RA, Cox C, Miller RK.

Obstet Gynecol. 2003 Jun;101(6):1266-74.PMID: 12798535 [PubMed - indexed for MEDLINE]Related articles

Altered amino acid levels in sera of a mouse model for juvenile neuronal ceroid lipofuscinoses.

Pearce DA, McCall K, Mooney RA, Chattopadhyay S, Curran TM.

Clin Chim Acta. 2003 Jun;332(1-2):145-8. No abstract available. PMID: 12763292 [PubMed - indexed for MEDLINE]Related articles

RNA polymerase mutations that impair conversion to a termination-resistant complex by Q antiterminator proteins.

Santangelo TJ, Mooney RA, Landick R, Roberts JW.

Genes Dev. 2003 May 15;17(10):1281-92.PMID: 12756229 [PubMed - indexed for MEDLINE]Related articlesFree article

The leukocyte common antigen-related protein LAR: candidate PTP for inhibitory targeting.

Mooney RA, LeVea CM.

Curr Top Med Chem. 2003;3(7):809-19. Review.PMID: 12678846 [PubMed - indexed for MEDLINE]Related articles

Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes.

Senn JJ, Klover PJ, Nowak IA, Zimmers TA, Koniaris LG, Furlanetto RW, Mooney RA.

J Biol Chem. 2003 Apr 18;278(16):13740-6. Epub 2003 Jan 30.PMID: 12560330 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin-6 induces cellular insulin resistance in hepatocytes.

Senn JJ, Klover PJ, Nowak IA, Mooney RA.

Diabetes. 2002 Dec;51(12):3391-9.PMID: 12453891 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutations of bacterial RNA polymerase leading to resistance to microcin j25.

Yuzenkova J, Delgado M, Nechaev S, Savalia D, Epshtein V, Artsimovitch I, Mooney RA, Landick R, Farias RN, Salomon R, Severinov K.

J Biol Chem. 2002 Dec 27;277(52):50867-75. Epub 2002 Oct 24.PMID: 12401787 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of the leucocyte common antigen-related (LAR) tyrosine phosphatase is regulated by cell density through functional E-cadherin complexes.

Symons JR, LeVea CM, Mooney RA.

Biochem J. 2002 Jul 15;365(Pt 2):513-9.PMID: 12095414 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor. A potential mechanism for cytokine-mediated insulin resistance.

Mooney RA, Senn J, Cameron S, Inamdar N, Boivin LM, Shang Y, Furlanetto RW.

J Biol Chem. 2001 Jul 13;276(28):25889-93. Epub 2001 May 7.PMID: 11342531 [PubMed - indexed for MEDLINE]Related articlesFree article

PTP LAR expression compared to prognostic indices in metastatic and non-metastatic breast cancer.

Levea CM, Mcgary CT, Symons JR, Mooney RA.

Breast Cancer Res Treat. 2000 Nov;64(2):221-8.PMID: 11194458 [PubMed - indexed for MEDLINE]Related articles

Direct localization of a beta-subunit domain on the three-dimensional structure of Escherichia coli RNA polymerase.

Opalka N, Mooney RA, Richter C, Severinov K, Landick R, Darst SA.

Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):617-22.PMID: 10639128 [PubMed - indexed for MEDLINE]Related articlesFree article

Dissociation of PTPase levels from their modulation of insulin receptor signal transduction.

Bleyle LA, Peng Y, Ellis C, Mooney RA.

Cell Signal. 1999 Oct;11(10):719-25.PMID: 10574326 [PubMed - indexed for MEDLINE]Related articles

RNA polymerase unveiled.

Mooney RA, Landick R.

Cell. 1999 Sep 17;98(6):687-90. Review. No abstract available. PMID: 10499791 [PubMed - indexed for MEDLINE]Related articles

Information processing by RNA polymerase: recognition of regulatory signals during RNA chain elongation.

Mooney RA, Artsimovitch I, Landick R.

J Bacteriol. 1998 Jul;180(13):3265-75. Review. No abstract available. PMID: 9642176 [PubMed - indexed for MEDLINE]Related articlesFree article

Maternal serum analyte levels in pregnancies with fetal Down syndrome resulting from translocations.

Saller DN Jr, Canick JA, Kellner LH, Rose NC, Garza J, French CA, Mooney RA.

Am J Obstet Gynecol. 1997 Oct;177(4):879-81.PMID: 9369838 [PubMed - indexed for MEDLINE]Related articles

Suppression of the protein tyrosine phosphatase LAR reduces apolipoprotein B secretion by McA-RH7777 rat hepatoma cells.

Phung TL, Mooney RA, Kulas DT, Sparks CE, Sparks JD.

Biochem Biophys Res Commun. 1997 Aug 18;237(2):367-71.PMID: 9268718 [PubMed - indexed for MEDLINE]Related articles

The protein tyrosine phosphatase LAR has a major impact on insulin receptor dephosphorylation.

Mooney RA, Kulas DT, Bleyle LA, Novak JS.

Biochem Biophys Res Commun. 1997 Jun 27;235(3):709-12.PMID: 9207225 [PubMed - indexed for MEDLINE]Related articles

The transmembrane protein-tyrosine phosphatase CD45 is associated with decreased insulin receptor signaling.

Kulas DT, Freund GG, Mooney RA.

J Biol Chem. 1996 Jan 12;271(2):755-60.PMID: 8557683 [PubMed - indexed for MEDLINE]Related articlesFree article

The transmembrane protein-tyrosine phosphatase LAR modulates signaling by multiple receptor tyrosine kinases.

Kulas DT, Goldstein BJ, Mooney RA.

J Biol Chem. 1996 Jan 12;271(2):748-54.PMID: 8557682 [PubMed - indexed for MEDLINE]Related articlesFree article

Decreased maternal serum hCG levels with increasing gravidity and parity.

Mooney RA, Arvan DA, Saller DN Jr, French CA, Peterson CJ.

Obstet Gynecol. 1995 Dec;86(6):900-5.PMID: 7501336 [PubMed - indexed for MEDLINE]Related articles

Insulin receptor signaling is augmented by antisense inhibition of the protein tyrosine phosphatase LAR.

Kulas DT, Zhang WR, Goldstein BJ, Furlanetto RW, Mooney RA.

J Biol Chem. 1995 Feb 10;270(6):2435-8.PMID: 7852302 [PubMed - indexed for MEDLINE]Related articlesFree article

The PI3-kinase serine kinase phosphorylates its p85 subunit and IRS-1 in PI3-kinase/IRS-1 complexes.

Freund GG, Wittig JG, Mooney RA.

Biochem Biophys Res Commun. 1995 Jan 5;206(1):272-8.PMID: 7818531 [PubMed - indexed for MEDLINE]Related articles

Differential effects of phosphotyrosine phosphatase expression on hormone-dependent and independent pp60c-src activity.

Way BA, Mooney RA.

Mol Cell Biochem. 1994 Oct 26;139(2):167-75.PMID: 7532275 [PubMed - indexed for MEDLINE]Related articles

Effectiveness of combining maternal serum alpha-fetoprotein and hCG in a second-trimester screening program for Down syndrome.

Mooney RA, Peterson CJ, French CA, Saller DN Jr, Arvan DA.

Obstet Gynecol. 1994 Aug;84(2):298-303.PMID: 7518896 [PubMed - indexed for MEDLINE]Related articles

Functional insulin and insulin-like growth factor-1 receptors are preferentially expressed in multiple myeloma cell lines as compared to B-lymphoblastoid cell lines.

Freund GG, Kulas DT, Way BA, Mooney RA.

Cancer Res. 1994 Jun 15;54(12):3179-85.PMID: 8205537 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of phosphatidylinositol-3-kinase by platelet-derived growth factor and insulin-like growth factor-1 is inhibited by a transmembrane phosphotyrosine phosphatase.

Way BA, Mooney RA.

J Biol Chem. 1993 Dec 15;268(35):26409-15.PMID: 8253766 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin and IGF-1 increase mitogenesis and glucose metabolism in the multiple myeloma cell line, RPMI 8226.

Freund GG, Kulas DT, Mooney RA.

J Immunol. 1993 Aug 15;151(4):1811-20.PMID: 7688386 [PubMed - indexed for MEDLINE]Related articles

Establishing a continence service using AHCPR guidelines.

Mooney RA, Newman DK, Smith DA, Grey M.

Ostomy Wound Manage. 1993 Apr;39(3):28-30, 32.PMID: 8507339 [PubMed - indexed for MEDLINE]Related articles

Expression of a transmembrane phosphotyrosine phosphatase inhibits cellular response to platelet-derived growth factor and insulin-like growth factor-1.

Mooney RA, Freund GG, Way BA, Bordwell KL.

J Biol Chem. 1992 Nov 25;267(33):23443-6.PMID: 1429686 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential dephosphorylation of the insulin receptor and its 160-kDa substrate (pp160) in rat adipocytes.

Mooney RA, Bordwell KL.

J Biol Chem. 1992 Jul 15;267(20):14054-60.PMID: 1321133 [PubMed - indexed for MEDLINE]Related articlesFree article