PubMed

Blocking LFA-1 activation with lovastatin prevents graft-versus-host disease in mouse bone marrow transplantation.

Wang Y, Li D, Jones D, Bassett R, Sale GE, Khalili J, Komanduri KV, Couriel DR, Champlin RE, Molldrem JJ, Ma Q.

Biol Blood Marrow Transplant. 2009 Dec;15(12):1513-22. Epub 2009 Oct 7.PMID: 19896074 [PubMed - in process]Related articles

LFA-1 regulates CD8+ T cell activation via T cell receptor-mediated and LFA-1-mediated Erk1/2 signal pathways.

Li D, Molldrem JJ, Ma Q.

J Biol Chem. 2009 Jul 31;284(31):21001-10. Epub 2009 May 29.PMID: 19483086 [PubMed - indexed for MEDLINE]Related articles

Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral epitopes.

Hanley PJ, Cruz CR, Savoldo B, Leen AM, Stanojevic M, Khalil M, Decker W, Molldrem JJ, Liu H, Gee AP, Rooney CM, Heslop HE, Dotti G, Brenner MK, Shpall EJ, Bollard CM.

Blood. 2009 Aug 27;114(9):1958-67. Epub 2009 May 14.PMID: 19443656 [PubMed - indexed for MEDLINE]Related articles

LFA-1 affinity regulation is necessary for the activation and proliferation of naive T cells.

Wang Y, Li D, Nurieva R, Yang J, Sen M, Carreño R, Lu S, McIntyre BW, Molldrem JJ, Legge GB, Ma Q.

J Biol Chem. 2009 May 8;284(19):12645-53. Epub 2009 Mar 18.PMID: 19297325 [PubMed - indexed for MEDLINE]Related articles

Phosphatidylinositol 3-kinase mediates bronchioalveolar stem cell expansion in mouse models of oncogenic K-ras-induced lung cancer.

Yang Y, Iwanaga K, Raso MG, Wislez M, Hanna AE, Wieder ED, Molldrem JJ, Wistuba II, Powis G, Demayo FJ, Kim CF, Kurie JM.

PLoS One. 2008 May 21;3(5):e2220.PMID: 18493606 [PubMed - indexed for MEDLINE]Related articlesFree article

High titer autoantibodies to GM-CSF in patients with AML, CML and MDS are associated with active disease.

Sergeeva A, Ono Y, Rios R, Molldrem JJ.

Leukemia. 2008 Apr;22(4):783-90. Epub 2008 Jan 24.PMID: 18216869 [PubMed - indexed for MEDLINE]Related articles

A novel strategy for rapid and efficient isolation of human tumor-specific CD4(+) and CD8(+) T-cell clones.

Lee ST, Liu S, Radvanyi L, Sukhumalchandra P, Molldrem JJ, Wieder ED, Hwu P, Liu YJ, Kwak LW, Lizée G, Neelapu SS.

J Immunol Methods. 2008 Feb 29;331(1-2):13-26. Epub 2007 Oct 9.PMID: 17959194 [PubMed - indexed for MEDLINE]Related articlesFree article

Delayed immune reconstitution after cord blood transplantation is characterized by impaired thymopoiesis and late memory T-cell skewing.

Komanduri KV, St John LS, de Lima M, McMannis J, Rosinski S, McNiece I, Bryan SG, Kaur I, Martin S, Wieder ED, Worth L, Cooper LJ, Petropoulos D, Molldrem JJ, Champlin RE, Shpall EJ.

Blood. 2007 Dec 15;110(13):4543-51. Epub 2007 Aug 1.PMID: 17671230 [PubMed - indexed for MEDLINE]Related articlesFree article

Risk factors associated with late cytomegalovirus reactivation after allogeneic stem cell transplantation for hematological malignancies.

Ozdemir E, Saliba RM, Champlin RE, Couriel DR, Giralt SA, de Lima M, Khouri IF, Hosing C, Kornblau SM, Anderlini P, Shpall EJ, Qazilbash MH, Molldrem JJ, Chemaly RF, Komanduri KV.

Bone Marrow Transplant. 2007 Jul;40(2):125-36. Epub 2007 May 28.PMID: 17530009 [PubMed - indexed for MEDLINE]Related articles

Display technologies: application for the discovery of drug and gene delivery agents.

Sergeeva A, Kolonin MG, Molldrem JJ, Pasqualini R, Arap W.

Adv Drug Deliv Rev. 2006 Dec 30;58(15):1622-54. Epub 2006 Oct 6. Review.PMID: 17123658 [PubMed - indexed for MEDLINE]Related articlesFree article

Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals.

Leen AM, Myers GD, Sili U, Huls MH, Weiss H, Leung KS, Carrum G, Krance RA, Chang CC, Molldrem JJ, Gee AP, Brenner MK, Heslop HE, Rooney CM, Bollard CM.

Nat Med. 2006 Oct;12(10):1160-6. Epub 2006 Sep 24.PMID: 16998485 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial DNA sequence variation in single cells from leukemia patients.

Yao YG, Ogasawara Y, Kajigaya S, Molldrem JJ, Falcão RP, Pintão MC, McCoy JP Jr, Rizzatti EG, Young NS.

Blood. 2007 Jan 15;109(2):756-62. Epub 2006 Aug 31.PMID: 16946307 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunotherapeutic peptide vaccination with leukemia-associated antigens.

Rusakiewicz S, Molldrem JJ.

Curr Opin Immunol. 2006 Oct;18(5):599-604. Epub 2006 Jul 25. Review.PMID: 16870418 [PubMed - indexed for MEDLINE]Related articles

Hookworm infection of sigmoid colon masquerading as graft-versus-host disease in an allogeneic stem cell transplant recipient after donor lymphocyte infusion for refractory acute promyelocytic leukemia.

Ozdemir E, Molldrem JJ.

Bone Marrow Transplant. 2006 Apr;37(8):785-6. No abstract available. PMID: 16501592 [PubMed - indexed for MEDLINE]Related articles

Vaccination for leukemia.

Molldrem JJ.

Biol Blood Marrow Transplant. 2006 Jan;12(1 Suppl 1):13-8. Review.PMID: 16399579 [PubMed - indexed for MEDLINE]Related articles

Vaccinating transplant recipients.

Molldrem JJ.

Nat Med. 2005 Nov;11(11):1162-3. No abstract available. PMID: 16270072 [PubMed - indexed for MEDLINE]Related articles

Assembly of the kappa preB receptor requires a V kappa-like protein encoded by a germline transcript.

Rangel R, McKeller MR, Sims-Mourtada JC, Kashi C, Cain K, Wieder ED, Molldrem JJ, Pham LV, Ford RJ, Yotnda P, Guret C, Francés V, Martinez-Valdez H.

J Biol Chem. 2005 May 6;280(18):17807-14. Epub 2005 Mar 9.PMID: 15757909 [PubMed - indexed for MEDLINE]Related articlesFree article

Vaccines in leukemia.

Lu S, Wieder E, Komanduri K, Ma Q, Molldrem JJ.

Adv Pharmacol. 2004;51:255-70. Review. No abstract available. PMID: 15464913 [PubMed - indexed for MEDLINE]Related articles

Functional assessment and specific depletion of alloreactive human T cells using flow cytometry.

Martins SL, St John LS, Champlin RE, Wieder ED, McMannis J, Molldrem JJ, Komanduri KV.

Blood. 2004 Dec 1;104(12):3429-36. Epub 2004 Jul 29.PMID: 15284108 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunity to chronic myelogenous leukemia.

Kurbegov D, Molldrem JJ.

Hematol Oncol Clin North Am. 2004 Jun;18(3):733-52, xi-xii. Review.PMID: 15271403 [PubMed - indexed for MEDLINE]Related articles

Immune-induced cytopenia: bone marrow failure syndrome.

Kondo Y, Molldrem JJ.

Curr Hematol Rep. 2004 May;3(3):178-83. Review.PMID: 15087065 [PubMed - indexed for MEDLINE]Related articles

Immunotherapy of hematologic malignancy.

Heslop HE, Stevenson FK, Molldrem JJ.

Hematology Am Soc Hematol Educ Program. 2003:331-49. Review.PMID: 14633789 [PubMed - indexed for MEDLINE]Related articlesFree article

CD25 expression on donor CD4+ or CD8+ T cells is associated with an increased risk for graft-versus-host disease after HLA-identical stem cell transplantation in humans.

Stanzani M, Martins SL, Saliba RM, St John LS, Bryan S, Couriel D, McMannis J, Champlin RE, Molldrem JJ, Komanduri KV.

Blood. 2004 Feb 1;103(3):1140-6. Epub 2003 Aug 7.PMID: 12907445 [PubMed - indexed for MEDLINE]Related articlesFree article

T-large granular lymphocyte lymphoproliferative disorder: expression of CD26 as a marker of clinically aggressive disease and characterization of marrow inhibition.

Dang NH, Aytac U, Sato K, O'Brien S, Melenhorst J, Morimoto C, Barrett AJ, Molldrem JJ.

Br J Haematol. 2003 Jun;121(6):857-65.PMID: 12786796 [PubMed - indexed for MEDLINE]Related articles

Selective depletion of donor alloreactive T cells without loss of antiviral or antileukemic responses.

Amrolia PJ, Muccioli-Casadei G, Yvon E, Huls H, Sili U, Wieder ED, Bollard C, Michalek J, Ghetie V, Heslop HE, Molldrem JJ, Rooney CM, Schlinder J, Vitetta E, Brenner MK.

Blood. 2003 Sep 15;102(6):2292-9. Epub 2003 May 22. Erratum in: Blood. 2004 Sep 15;104(6):1605. PMID: 12763937 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic myelogenous leukemia shapes host immunity by selective deletion of high-avidity leukemia-specific T cells.

Molldrem JJ, Lee PP, Kant S, Wieder E, Jiang W, Lu S, Wang C, Davis MM.

J Clin Invest. 2003 Mar;111(5):639-47.PMID: 12618518 [PubMed - indexed for MEDLINE]Related articlesFree article

The basis of T-cell-mediated immunity to chronic myelogenous leukemia.

Molldrem JJ, Kant S, Jiang W, Lu S.

Oncogene. 2002 Dec 9;21(56):8668-73. Review. No abstract available. PMID: 12476312 [PubMed - indexed for MEDLINE]Related articlesFree article

Antigen-specific lymphocyte therapies.

Molldrem JJ.

Cytotherapy. 2002;4(4):315-6. No abstract available. PMID: 12396830 [PubMed - indexed for MEDLINE]Related articles

Overexpressed differentiation antigens as targets of graft-versus-leukemia reactions.

Molldrem JJ, Komanduri K, Wieder E.

Curr Opin Hematol. 2002 Nov;9(6):503-8. Review.PMID: 12394172 [PubMed - indexed for MEDLINE]Related articles

Loss of T-lymphocyte clonal dominance in patients with myelodysplastic syndrome responsive to immunosuppression.

Kochenderfer JN, Kobayashi S, Wieder ED, Su C, Molldrem JJ.

Blood. 2002 Nov 15;100(10):3639-45. Epub 2002 Jul 5.PMID: 12393644 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytomegalovirus reactivation following allogeneic stem cell transplantation is associated with the presence of dysfunctional antigen-specific CD8+ T cells.

Ozdemir E, St John LS, Gillespie G, Rowland-Jones S, Champlin RE, Molldrem JJ, Komanduri KV.

Blood. 2002 Nov 15;100(10):3690-7. Epub 2002 Jul 5.PMID: 12393402 [PubMed - indexed for MEDLINE]Related articlesFree article

Antithymocyte globulin for treatment of the bone marrow failure associated with myelodysplastic syndromes.

Molldrem JJ, Leifer E, Bahceci E, Saunthararajah Y, Rivera M, Dunbar C, Liu J, Nakamura R, Young NS, Barrett AJ.

Ann Intern Med. 2002 Aug 6;137(3):156-63.PMID: 12160363 [PubMed - indexed for MEDLINE]Related articlesFree article

A human Mix-like homeobox gene MIXL shows functional similarity to Xenopus Mix.1.

Guo W, Chan AP, Liang H, Wieder ED, Molldrem JJ, Etkin LD, Nagarajan L.

Blood. 2002 Jul 1;100(1):89-95.PMID: 12070013 [PubMed - indexed for MEDLINE]Related articlesFree article

Leukemia vaccines.

Kochenderfer JN, Molldrem JJ.

Curr Oncol Rep. 2001 May;3(3):193-200. Review.PMID: 11296128 [PubMed - indexed for MEDLINE]Related articles

Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia.

Molldrem JJ, Lee PP, Wang C, Felio K, Kantarjian HM, Champlin RE, Davis MM.

Nat Med. 2000 Sep;6(9):1018-23.PMID: 10973322 [PubMed - indexed for MEDLINE]Related articles

A PR1-human leukocyte antigen-A2 tetramer can be used to isolate low-frequency cytotoxic T lymphocytes from healthy donors that selectively lyse chronic myelogenous leukemia.

Molldrem JJ, Lee PP, Wang C, Champlin RE, Davis MM.

Cancer Res. 1999 Jun 1;59(11):2675-81.PMID: 10363991 [PubMed - indexed for MEDLINE]Related articlesFree article

Haematological response of patients with myelodysplastic syndrome to antithymocyte globulin is associated with a loss of lymphocyte-mediated inhibition of CFU-GM and alterations in T-cell receptor Vbeta profiles.

Molldrem JJ, Jiang YZ, Stetler-Stevenson M, Mavroudis D, Hensel N, Barrett AJ.

Br J Haematol. 1998 Sep;102(5):1314-22.PMID: 9753062 [PubMed - indexed for MEDLINE]Related articles

Antithymocyte globulin for patients with myelodysplastic syndrome.

Molldrem JJ, Caples M, Mavroudis D, Plante M, Young NS, Barrett AJ.

Br J Haematol. 1997 Dec;99(3):699-705.PMID: 9401087 [PubMed - indexed for MEDLINE]Related articles

Cytotoxic T lymphocytes specific for a nonpolymorphic proteinase 3 peptide preferentially inhibit chronic myeloid leukemia colony-forming units.

Molldrem JJ, Clave E, Jiang YZ, Mavroudis D, Raptis A, Hensel N, Agarwala V, Barrett AJ.

Blood. 1997 Oct 1;90(7):2529-34.PMID: 9326217 [PubMed - indexed for MEDLINE]Related articlesFree article