PubMed

Nephrin is expressed on the surface of insulin vesicles and facilitates glucose stimulated insulin release.

Fornoni A, Jeon J, Santos JV, Cobianchi L, Jauregui A, Inverardi L, Mandic SA, Bark C, Johnson K, McNamara G, Pileggi A, Molano RD, Reiser J, Tryggvason K, Kerjaschki D, Berggren PO, Mundel P, Ricordi C.

Diabetes. 2009 Oct 28. [Epub ahead of print]PMID: 19833886 [PubMed - as supplied by publisher]Related articles

Effects of pancreas cold ischemia on islet function and quality.

Pileggi A, Ribeiro MM, Hogan AR, Molano RD, Embury JE, Ichii H, Cobianchi L, Fornoni A, Ricordi C, Pastori RL.

Transplant Proc. 2009 Jun;41(5):1808-9.PMID: 19545733 [PubMed - indexed for MEDLINE]Related articles

Impact of pancreatic cold preservation on rat islet recovery and function.

Pileggi A, Ribeiro MM, Hogan AR, Molano RD, Cobianchi L, Ichii H, Embury J, Inverardi L, Fornoni A, Ricordi C, Pastori RL.

Transplantation. 2009 May 27;87(10):1442-50.PMID: 19461479 [PubMed - indexed for MEDLINE]Related articles

Ischemic preconditioning improves islet recovery after pancreas cold preservation.

Hogan AR, Doni M, Ribeiro MM, Molano RD, Cobianchi L, Molina J, Zahr E, Ricordi C, Pastori RL, Pileggi A.

Transplant Proc. 2009 Jan-Feb;41(1):354-5.PMID: 19249556 [PubMed - indexed for MEDLINE]Related articles

Effects of systemic immunosuppression on islet engraftment and function into a subcutaneous biocompatible device.

Marzorati S, Bocca N, Molano RD, Hogan AR, Doni M, Cobianchi L, Inverardi L, Ricordi C, Pileggi A.

Transplant Proc. 2009 Jan-Feb;41(1):352-3.PMID: 19249555 [PubMed - indexed for MEDLINE]Related articles

Inhibition of C-jun N-terminal kinase improves insulin sensitivity but worsens albuminuria in experimental diabetes.

Ijaz A, Tejada T, Catanuto P, Xia X, Elliot SJ, Lenz O, Jauregui A, Saenz MO, Molano RD, Pileggi A, Ricordi C, Fornoni A.

Kidney Int. 2009 Feb;75(4):381-8. Epub 2008 Oct 29.PMID: 18971923 [PubMed - indexed for MEDLINE]Related articles

c-Jun N-terminal kinase 1 is deleterious to the function and survival of murine pancreatic islets.

Varona-Santos JL, Pileggi A, Molano RD, Sanabria NY, Ijaz A, Atsushi M, Ichii H, Pastori RL, Inverardi L, Ricordi C, Fornoni A.

Diabetologia. 2008 Dec;51(12):2271-80. Epub 2008 Oct 14.PMID: 18853132 [PubMed - indexed for MEDLINE]Related articles

Characterization of pancreatic ductal cells in human islet preparations.

Ichii H, Miki A, Yamamoto T, Molano RD, Barker S, Mita A, Rodriguez-Diaz R, Klein D, Pastori R, Alejandro R, Inverardi L, Pileggi A, Ricordi C.

Lab Invest. 2008 Nov;88(11):1167-77. Epub 2008 Sep 8.PMID: 18779781 [PubMed - indexed for MEDLINE]Related articlesFree article

Human alpha 1-antitrypsin therapy induces fatal anaphylaxis in non-obese diabetic mice.

Lu Y, Parker M, Pileggi A, Zhang B, Choi YK, Molano RD, Wasserfall C, Ricordi C, Inverardi L, Brantly M, Schatz D, Atkinson M, Song S.

Clin Exp Immunol. 2008 Oct;154(1):15-21. Epub 2008 Aug 28.PMID: 18759852 [PubMed - indexed for MEDLINE]Related articlesFree article

Riboflavin inhibits IL-6 expression and p38 activation in islet cells.

Cobianchi L, Fornoni A, Pileggi A, Molano RD, Sanabria NY, Gonzalez-Quintana J, Bocca N, Marzorati S, Zahr E, Hogan AR, Ricordi C, Inverardi L.

Cell Transplant. 2008;17(5):559-66.PMID: 18714675 [PubMed - indexed for MEDLINE]Related articles

Soft corticosteroids for local immunosuppression: exploring the possibility for the use of loteprednol etabonate for islet transplantation.

Bocca N, Pileggi A, Molano RD, Marzorati S, Wu W, Bodor N, Ricordi C, Buchwald P.

Pharmazie. 2008 Mar;63(3):226-32.PMID: 18444512 [PubMed - indexed for MEDLINE]Related articles

Alpha-1 antitrypsin treatment of spontaneously diabetic nonobese diabetic mice receiving islet allografts.

Pileggi A, Molano RD, Song S, Zahr E, SanJose S, Villate S, Wasserfall C, Ricordi C, Atkinson MA, Inverardi L.

Transplant Proc. 2008 Mar;40(2):457-8.PMID: 18374100 [PubMed - indexed for MEDLINE]Related articles

Prolonged islet allograft survival by alpha-1 antitrypsin: the role of humoral immunity.

Molano RD, Pileggi A, Song S, Zahr E, San Jose S, Molina J, Fort A, Wasserfall C, Ricordi C, Atkinson MA, Inverardi L.

Transplant Proc. 2008 Mar;40(2):455-6.PMID: 18374099 [PubMed - indexed for MEDLINE]Related articles

Rapamycin impairs beta-cell proliferation in vivo.

Zahr E, Molano RD, Pileggi A, Ichii H, San Jose S, Bocca N, An W, Gonzalez-Quintana J, Fraker C, Ricordi C, Inverardi L.

Transplant Proc. 2008 Mar;40(2):436-7.PMID: 18374093 [PubMed - indexed for MEDLINE]Related articles

beta-Cell specific cytoprotection by prolactin on human islets.

Yamamoto T, Ricordi C, Mita A, Miki A, Sakuma Y, Molano RD, Fornoni A, Pileggi A, Inverardi L, Ichii H.

Transplant Proc. 2008 Mar;40(2):382-3.PMID: 18374075 [PubMed - indexed for MEDLINE]Related articlesFree article

Noninvasive in vivo imaging of pancreatic islet cell biology.

Speier S, Nyqvist D, Cabrera O, Yu J, Molano RD, Pileggi A, Moede T, Köhler M, Wilbertz J, Leibiger B, Ricordi C, Leibiger IB, Caicedo A, Berggren PO.

Nat Med. 2008 May;14(5):574-8. Epub 2008 Mar 7.PMID: 18327249 [PubMed - indexed for MEDLINE]Related articles

Rapamycin impairs in vivo proliferation of islet beta-cells.

Zahr E, Molano RD, Pileggi A, Ichii H, Jose SS, Bocca N, An W, Gonzalez-Quintana J, Fraker C, Ricordi C, Inverardi L.

Transplantation. 2007 Dec 27;84(12):1576-83.PMID: 18165767 [PubMed - indexed for MEDLINE]Related articles

Quantitative differential expression analysis reveals miR-7 as major islet microRNA.

Bravo-Egana V, Rosero S, Molano RD, Pileggi A, Ricordi C, Domínguez-Bendala J, Pastori RL.

Biochem Biophys Res Commun. 2008 Feb 22;366(4):922-6. Epub 2007 Dec 18.PMID: 18086561 [PubMed - indexed for MEDLINE]Related articles

Inhibition of c-jun N terminal kinase (JNK) improves functional beta cell mass in human islets and leads to AKT and glycogen synthase kinase-3 (GSK-3) phosphorylation.

Fornoni A, Pileggi A, Molano RD, Sanabria NY, Tejada T, Gonzalez-Quintana J, Ichii H, Inverardi L, Ricordi C, Pastori RL.

Diabetologia. 2008 Feb;51(2):298-308. Epub 2007 Dec 8.PMID: 18066521 [PubMed - indexed for MEDLINE]Related articles

The l-isoform but not d-isoforms of a JNK inhibitory peptide protects pancreatic beta-cells.

Fornoni A, Cobianchi L, Sanabria NY, Pileggi A, Molano RD, Ichii H, Rosero S, Inverardi L, Ricordi C, Pastori RL.

Biochem Biophys Res Commun. 2007 Mar 2;354(1):227-33. Epub 2007 Jan 2.PMID: 17222390 [PubMed - indexed for MEDLINE]Related articles

Reversal of diabetes by pancreatic islet transplantation into a subcutaneous, neovascularized device.

Pileggi A, Molano RD, Ricordi C, Zahr E, Collins J, Valdes R, Inverardi L.

Transplantation. 2006 May 15;81(9):1318-24.PMID: 16699461 [PubMed - indexed for MEDLINE]Related articles

Systemic overexpression of interleukin-10 fails to protect allogeneic islet transplants in nonobese diabetic mice.

Zhang YC, Pileggi A, Molano RD, Wasserfall C, Campbell-Thompson M, Ricordi C, Atkinson MA, Inverardi L.

Transplantation. 2005 Aug 27;80(4):530-3.PMID: 16123729 [PubMed - indexed for MEDLINE]Related articles

Delivery of TAT/PTD-fused proteins/peptides to islets via pancreatic duct.

Klein D, Mendoza V, Pileggi A, Molano RD, Barbé-Tuana FM, Inverardi L, Ricordi C, Pastori RL.

Cell Transplant. 2005;14(5):241-8.PMID: 16052906 [PubMed - indexed for MEDLINE]Related articles

A novel method for the assessment of cellular composition and beta-cell viability in human islet preparations.

Ichii H, Inverardi L, Pileggi A, Molano RD, Cabrera O, Caicedo A, Messinger S, Kuroda Y, Berggren PO, Ricordi C.

Am J Transplant. 2005 Jul;5(7):1635-45.PMID: 15943621 [PubMed - indexed for MEDLINE]Related articles

Prolonged allogeneic islet graft survival by protoporphyrins.

Pileggi A, Molano RD, Berney T, Ichii H, San Jose S, Zahr E, Poggioli R, Linetsky E, Ricordi C, Inverardi L.

Cell Transplant. 2005;14(2-3):85-96.PMID: 15881418 [PubMed - indexed for MEDLINE]Related articles

A functional CD40 receptor is expressed in pancreatic beta cells.

Klein D, Barbé-Tuana F, Pugliese A, Ichii H, Garza D, Gonzalez M, Molano RD, Ricordi C, Pastori RL.

Diabetologia. 2005 Feb;48(2):268-76. Epub 2005 Feb 3.PMID: 15690148 [PubMed - indexed for MEDLINE]Related articles

Rescue purification maximizes the use of human islet preparations for transplantation.

Ichii H, Pileggi A, Molano RD, Baidal DA, Khan A, Kuroda Y, Inverardi L, Goss JA, Alejandro R, Ricordi C.

Am J Transplant. 2005 Jan;5(1):21-30.PMID: 15636608 [PubMed - indexed for MEDLINE]Related articles

Delivery of Bcl-XL or its BH4 domain by protein transduction inhibits apoptosis in human islets.

Klein D, Ribeiro MM, Mendoza V, Jayaraman S, Kenyon NS, Pileggi A, Molano RD, Inverardi L, Ricordi C, Pastori RL.

Biochem Biophys Res Commun. 2004 Oct 15;323(2):473-8.PMID: 15369775 [PubMed - indexed for MEDLINE]Related articles

Targeted bone marrow radioablation with 153Samarium-lexidronam promotes allogeneic hematopoietic chimerism and donor-specific immunologic hyporesponsiveness.

Inverardi L, Linetsky E, Pileggi A, Molano RD, Serafini A, Paganelli G, Ricordi C.

Transplantation. 2004 Mar 15;77(5):647-55.PMID: 15021823 [PubMed - indexed for MEDLINE]Related articles

Adenoviral gene transfer of erythropoietin confers cytoprotection to isolated pancreatic islets.

Fenjves ES, Ochoa MS, Gay-Rabinstein C, Molano RD, Pileggi A, Mendez AJ, Inverardi L, Ricordi C.

Transplantation. 2004 Jan 15;77(1):13-8.PMID: 14724429 [PubMed - indexed for MEDLINE]Related articles

The effect of simultaneous CD154 and LFA-1 blockade on the survival of allogeneic islet grafts in nonobese diabetic mice.

Berney T, Pileggi A, Molano RD, Poggioli R, Zahr E, Ricordi C, Inverardi L.

Transplantation. 2003 Dec 27;76(12):1669-74.PMID: 14688513 [PubMed - indexed for MEDLINE]Related articles

Long-term islet allograft survival in nonobese diabetic mice treated with tacrolimus, rapamycin, and anti-interleukin-2 antibody.

Molano RD, Pileggi A, Berney T, Poggioli R, Zahr E, Oliver R, Malek TR, Ricordi C, Inverardi L.

Transplantation. 2003 Jun 15;75(11):1812-9.PMID: 12811239 [PubMed - indexed for MEDLINE]Related articles

Heme oxygenase-1 fused to a TAT peptide transduces and protects pancreatic beta-cells.

Ribeiro MM, Klein D, Pileggi A, Molano RD, Fraker C, Ricordi C, Inverardi L, Pastori RL.

Biochem Biophys Res Commun. 2003 Jun 13;305(4):876-81.PMID: 12767912 [PubMed - indexed for MEDLINE]Related articles

Nonlethal conditioning for the induction of allogeneic chimerism and tolerance to islet allografts.

Li H, Inverardi L, Molano RD, Pileggi A, Ricordi C.

Transplantation. 2003 Apr 15;75(7):966-70.PMID: 12698081 [PubMed - indexed for MEDLINE]Related articles

Prolonged islet allograft survival in diabetic NOD mice by targeting CD45RB and CD154.

Molano RD, Pileggi A, Berney T, Poggioli R, Zahr E, Oliver R, Ricordi C, Rothstein DM, Basadonna GP, Inverardi L.

Diabetes. 2003 Apr;52(4):957-64.PMID: 12663467 [PubMed - indexed for MEDLINE]Related articlesFree article

Adeno-associated virus-mediated IL-10 gene therapy inhibits diabetes recurrence in syngeneic islet cell transplantation of NOD mice.

Zhang YC, Pileggi A, Agarwal A, Molano RD, Powers M, Brusko T, Wasserfall C, Goudy K, Zahr E, Poggioli R, Scott-Jorgensen M, Campbell-Thompson M, Crawford JM, Nick H, Flotte T, Ellis TM, Ricordi C, Inverardi L, Atkinson MA.

Diabetes. 2003 Mar;52(3):708-16.PMID: 12606512 [PubMed - indexed for MEDLINE]Related articlesFree article

Adeno-associated virus transduction of islets with interleukin-4 results in impaired metabolic function in syngeneic marginal islet mass transplantation.

Zhang YC, Molano RD, Pileggi A, Powers M, Cross J, Wasserfall C, Scott-Jorgensen M, Campbell-Thompson M, Crawford JM, Flotte T, Ellis TM, Ricordi C, Atkinson MA, Inverardi L.

Transplantation. 2002 Oct 27;74(8):1184-6.PMID: 12438968 [PubMed - indexed for MEDLINE]Related articles

Efficient transduction of pancreatic islets by feline immunodeficiency virus vectors1.

Curran MA, Ochoa MS, Molano RD, Pileggi A, Inverardi L, Kenyon NS, Nolan GP, Ricordi C, Fenjves ES.

Transplantation. 2002 Aug 15;74(3):299-306.PMID: 12177606 [PubMed - indexed for MEDLINE]Related articles

Neonatal porcine pancreatic cell clusters as a potential source for transplantation in humans: characterization of proliferation, apoptosis, xenoantigen expression and gene delivery with recombinant AAV.

Vizzardelli C, Molano RD, Pileggi A, Berney T, Cattan P, Fenjves ES, Peel A, Fraker C, Ricordi C, Inverardi L.

Xenotransplantation. 2002 Jan;9(1):14-24.PMID: 12005100 [PubMed - indexed for MEDLINE]Related articles

Transduction of human and mouse pancreatic islet cells using a bicistronic recombinant adeno-associated viral vector.

Kapturczak M, Zolotukhin S, Cross J, Pileggi A, Molano RD, Jorgensen M, Byrne B, Flotte TR, Ellis T, Inverardi L, Ricordi C, Nick H, Atkinson M, Agarwal A.

Mol Ther. 2002 Feb;5(2):154-60.PMID: 11829522 [PubMed - indexed for MEDLINE]Related articlesFree article

Absence of CSF-1-dependent macrophages does not improve function of transplanted islets of Langerhans.

Berney T, Molano RD, Pileggi A, Cattan P, Vizzardelli C, Ricordi C, Inverardi L.

Cell Transplant. 2001;10(7):633-7.PMID: 11714198 [PubMed - indexed for MEDLINE]Related articles

Heme oxygenase-1 induction in islet cells results in protection from apoptosis and improved in vivo function after transplantation.

Pileggi A, Molano RD, Berney T, Cattan P, Vizzardelli C, Oliver R, Fraker C, Ricordi C, Pastori RL, Bach FH, Inverardi L.

Diabetes. 2001 Sep;50(9):1983-91.PMID: 11522663 [PubMed - indexed for MEDLINE]Related articlesFree article

Proteins linked to a protein transduction domain efficiently transduce pancreatic islets.

Embury J, Klein D, Pileggi A, Ribeiro M, Jayaraman S, Molano RD, Fraker C, Kenyon N, Ricordi C, Inverardi L, Pastori RL.

Diabetes. 2001 Aug;50(8):1706-13.PMID: 11473028 [PubMed - indexed for MEDLINE]Related articlesFree article

Patterns of engraftment in different strains of immunodeficient mice reconstituted with human peripheral blood lymphocytes.

Berney T, Molano RD, Pileggi A, Cattan P, Li H, Ricordi C, Inverardi L.

Transplantation. 2001 Jul 15;72(1):133-40.PMID: 11468548 [PubMed - indexed for MEDLINE]Related articles

Early assessment of apoptosis in isolated islets of Langerhans.

Cattan P, Berney T, Schena S, Molano RD, Pileggi A, Vizzardelli C, Ricordi C, Inverardi L.

Transplantation. 2001 Apr 15;71(7):857-62.PMID: 11349716 [PubMed - indexed for MEDLINE]Related articles

Prolonged islet graft survival in NOD mice by blockade of the CD40-CD154 pathway of T-cell costimulation.

Molano RD, Berney T, Li H, Cattan P, Pileggi A, Vizzardelli C, Kenyon NS, Ricordi C, Burkly LC, Inverardi L.

Diabetes. 2001 Feb;50(2):270-6.PMID: 11272136 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential engraftment of human peripheral blood lymphocytes in various strains of immunodeficient mice.

Berney T, Molano RD, Pileggi A, Ricordi C, Inverardi L.

Transplant Proc. 2001 Feb-Mar;33(1-2):764-5. No abstract available. PMID: 11267059 [PubMed - indexed for MEDLINE]Related articles

Absence of M-CSF-dependent tissue macrophages does not improve delayed function of islet of Langerhans grafts.

Berney T, Molano RD, Pileggi A, Cattan P, Vizzardelli C, Ricordi C, Inverardi L.

Transplant Proc. 2001 Feb-Mar;33(1-2):356-7. No abstract available. PMID: 11266859 [PubMed - indexed for MEDLINE]Related articles

HO-1 upregulation protects the pancreatic cell line betaTC3 from cytokines and Fas-induced apoptosis.

Pileggi A, Cattan P, Berney T, Molano RD, Vizzardelli C, Ricordi C, Bach FH, Inverardi L.

Transplant Proc. 2001 Feb-Mar;33(1-2):266-7. No abstract available. PMID: 11266812 [PubMed - indexed for MEDLINE]Related articles

Early assessment of apoptosis in isolated islets of Langerhans.

Cattan P, Berney T, Schena S, Molano RD, Pileggi A, Vizzardelli C, Ricordi C, Inverardi L.

Transplant Proc. 2001 Feb-Mar;33(1-2):264-5. No abstract available. PMID: 11266811 [PubMed - indexed for MEDLINE]Related articles