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2008 1
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2020 12
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2023 22
2024 7

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Page 1
Probiotic mechanisms of action.
Bermudez-Brito M, Plaza-Díaz J, Muñoz-Quezada S, Gómez-Llorente C, Gil A. Bermudez-Brito M, et al. Ann Nutr Metab. 2012;61(2):160-74. doi: 10.1159/000342079. Epub 2012 Oct 2. Ann Nutr Metab. 2012. PMID: 23037511 Free article. Review.
Accumulating evidence demonstrates that probiotics communicate with the host by pattern recognition receptors, such as toll-like receptors and nucleotide-binding oligomerization domain-containing protein-like receptors, which modulate key signaling pathways, such as nuclea …
Accumulating evidence demonstrates that probiotics communicate with the host by pattern recognition receptors, such as toll-like receptors a …
Clinical Activity of Mitogen-Activated Protein Kinase-Targeted Therapies in Patients With Non-V600 BRAF-Mutant Tumors.
Dankner M, Wang Y, Fazelzad R, Johnson B, Nebhan CA, Dagogo-Jack I, Myall NJ, Richtig G, Bracht JWP, Gerlinger M, Shinozaki E, Yoshino T, Kotani D, Fangusaro JR, Gautschi O, Mazieres J, Sosman JA, Kopetz S, Subbiah V, Davies MA, Groover AL, Sullivan RJ, Flaherty KT, Johnson DB, Benedetti A, Cescon DW, Spreafico A, Zogopoulos G, Rose AAN. Dankner M, et al. JCO Precis Oncol. 2022 Aug;6:e2200107. doi: 10.1200/PO.22.00107. JCO Precis Oncol. 2022. PMID: 35977349 Free PMC article.
METHODS: We performed a systematic review and meta-analysis with published reports of individual patients with cancer harboring class 2 or 3 BRAF mutations from 2010 to 2021, to assess treatment outcomes with US Food and Drug Administration-approved mitogen-activated
METHODS: We performed a systematic review and meta-analysis with published reports of individual patients with cancer harboring class 2 or 3 …
A systematic review of p53 regulation of oxidative stress in skeletal muscle.
Beyfuss K, Hood DA. Beyfuss K, et al. Redox Rep. 2018 Dec;23(1):100-117. doi: 10.1080/13510002.2017.1416773. Epub 2018 Jan 3. Redox Rep. 2018. PMID: 29298131 Free PMC article. Review.
BACKGROUND: p53 is a tumor suppressor protein involved in regulating a wide array of signaling pathways. ...ABBREVIATIONS: Acadl: acyl-CoA dehydrogenase, long chain; Acadm: acyl-CoA dehydrogenase, C-4 to C-12 straight chain; AIF: apoptosis-inducing factor; Akt: protein
BACKGROUND: p53 is a tumor suppressor protein involved in regulating a wide array of signaling pathways. ...ABBREVIATIONS: Acadl: acy …
Time Course Evaluation of Mitogen-Activated Protein Kinase Phosphorylation to Resistance Exercise: A Systematic Review.
Lee CJ, Nicoll JX. Lee CJ, et al. J Strength Cond Res. 2023 Mar 1;37(3):710-725. doi: 10.1519/JSC.0000000000004409. Epub 2023 Jan 18. J Strength Cond Res. 2023. PMID: 36727997
Lee, CJ and Nicoll, JX. Time course evaluation of mitogen-activated protein kinase phosphorylation to resistance exercise: a systematic review. J Strength Cond Res 37(3): 710-725, 2023-Resistance exercise (RE) can increase the signaling activities of …
Lee, CJ and Nicoll, JX. Time course evaluation of mitogen-activated protein kinase phosphorylation to resistance …
Systematic review of p38 mitogen-activated kinase and its functional role in reproductive tissues.
Sheller-Miller S, Richardson L, Martin L, Jin J, Menon R. Sheller-Miller S, et al. Am J Reprod Immunol. 2018 Dec;80(6):e13047. doi: 10.1111/aji.13047. Epub 2018 Sep 4. Am J Reprod Immunol. 2018. PMID: 30178469 Free PMC article.
Oxidative stress (OS) plays a role in uterine tissue remodeling during pregnancy and parturition. While p38 MAPK is an OS-response kinase, a precise functional role is unknown. Therefore, we conducted a systematic review of literature on p38 MAPK expression, activation, an …
Oxidative stress (OS) plays a role in uterine tissue remodeling during pregnancy and parturition. While p38 MAPK is an OS-response kinase
Mitogen-activated protein kinase (MEK) inhibitors to treat melanoma alone or in combination with other kinase inhibitors.
Faghfuri E, Nikfar S, Niaz K, Faramarzi MA, Abdollahi M. Faghfuri E, et al. Expert Opin Drug Metab Toxicol. 2018 Mar;14(3):317-330. doi: 10.1080/17425255.2018.1432593. Epub 2018 Jan 30. Expert Opin Drug Metab Toxicol. 2018. PMID: 29363351 Review.
Areas covered: The aim of the current review is to present an update on the role of MEK in progressive melanomas and summarize latest results of clinical studies with innovative MEK inhibitors and/or combined approaches with other kinase inhibitors such as BRAF inhibitors …
Areas covered: The aim of the current review is to present an update on the role of MEK in progressive melanomas and summarize latest result …
Lipid metabolism in cancer: A systematic review.
Khan W, Augustine D, Rao RS, Patil S, Awan KH, Sowmya SV, Haragannavar VC, Prasad K. Khan W, et al. J Carcinog. 2021 May 6;20:4. doi: 10.4103/jcar.JCar_15_20. eCollection 2021. J Carcinog. 2021. PMID: 34321955 Free PMC article. Review.
The pathway most commonly involved in lipid metabolism in cancer was the phosphoinositide 3-kinase/protein kinase B (PI3K/Akt) signaling pathway, followed by the mitogen activated protein kinase (MAPK) pathway. SCD1 and FASN play s …
The pathway most commonly involved in lipid metabolism in cancer was the phosphoinositide 3-kinase/protein kinase B (PI …
Curcumin and rheumatoid arthritis: A systematic review of literature.
Pourhabibi-Zarandi F, Shojaei-Zarghani S, Rafraf M. Pourhabibi-Zarandi F, et al. Int J Clin Pract. 2021 Oct;75(10):e14280. doi: 10.1111/ijcp.14280. Epub 2021 May 24. Int J Clin Pract. 2021. PMID: 33914984 Review.
RESULTS: Most studies have shown the curative effects of curcumin on clinical and inflammatory parameters of RA and reported different mechanisms; inhibition of mitogen-activated protein kinase family, extracellular signal-regulated protein k
RESULTS: Most studies have shown the curative effects of curcumin on clinical and inflammatory parameters of RA and reported different mecha …
Systematic review to establish the safety profiles for direct and indirect inhibitors of p38 Mitogen-activated protein kinases for treatment of cancer. A systematic review of the literature.
Noel JK, Crean S, Claflin JE, Ranganathan G, Linz H, Lahn M. Noel JK, et al. Med Oncol. 2008;25(3):323-30. doi: 10.1007/s12032-008-9039-1. Epub 2008 Jan 19. Med Oncol. 2008. PMID: 18204822 Review.
OBJECTIVE: To identify potential tolerability issues for a novel selective p38 Mitogen-activated Protein Kinases (p38MAPK) inhibitor, we performed a systematic review of published studies and abstracts reporting safety outcomes for indirect inhibitors …
OBJECTIVE: To identify potential tolerability issues for a novel selective p38 Mitogen-activated Protein Kinases
95 results