PubMed

Phase II Study of Flavopiridol in Relapsed Chronic Lymphocytic Leukemia Demonstrating High Response Rates in Genetically High-Risk Disease.

Lin TS, Ruppert AS, Johnson AJ, Fischer B, Heerema NA, Andritsos LA, Blum KA, Flynn JM, Jones JA, Hu W, Moran ME, Mitchell SM, Smith LL, Wagner AJ, Raymond CA, Schaaf LJ, Phelps MA, Villalona-Calero MA, Grever MR, Byrd JC.

J Clin Oncol. 2009 Oct 13. [Epub ahead of print]PMID: 19826119 [PubMed - as supplied by publisher]Related articles

High frequencies of elevated alkaline phosphatase activity and rickets exist in extremely low birth weight infants despite current nutritional support.

Mitchell SM, Rogers SP, Hicks PD, Hawthorne KM, Parker BR, Abrams SA.

BMC Pediatr. 2009 Jul 29;9:47.PMID: 19640269 [PubMed - indexed for MEDLINE]Related articlesFree article

Development and ultrastructure of Cystoisospora canis Nemeséri, 1959 (syn. Isospora canis) monozoitc cysts in two non-canine cell lines.

Mitchell SM, Zajac AM, Lindsay DS.

J Parasitol. 2009 Jan 16:1. [Epub ahead of print]PMID: 19152237 [PubMed - as supplied by publisher]Related articles

Clinical response and pharmacokinetics from a phase 1 study of an active dosing schedule of flavopiridol in relapsed chronic lymphocytic leukemia.

Phelps MA, Lin TS, Johnson AJ, Hurh E, Rozewski DM, Farley KL, Wu D, Blum KA, Fischer B, Mitchell SM, Moran ME, Brooker-McEldowney M, Heerema NA, Jarjoura D, Schaaf LJ, Byrd JC, Grever MR, Dalton JT.

Blood. 2009 Mar 19;113(12):2637-45. Epub 2008 Nov 3.PMID: 18981292 [PubMed - indexed for MEDLINE]Related articles

Inhibition of Toxoplasma gondii and Plasmodium falciparum infections in vitro by NSC3852, a redox active antiproliferative and tumor cell differentiation agent.

Strobl JS, Seibert CW, Li Y, Nagarkatti R, Mitchell SM, Rosypal AC, Rathore D, Lindsay DS.

J Parasitol. 2009 Feb;95(1):215-23.PMID: 18837587 [PubMed - indexed for MEDLINE]Related articles

Effect of diathermy on muscle temperature, electromyography, and mechanomyography.

Mitchell SM, Trowbridge CA, Fincher AL, Cramer JT.

Muscle Nerve. 2008 Aug;38(2):992-1004.PMID: 18642378 [PubMed - indexed for MEDLINE]Related articles

Effects of high pressure processing on Toxoplasma gondii oocysts on raspberries.

Lindsay DS, Holliman D, Flick GJ, Goodwin DG, Mitchell SM, Dubey JP.

J Parasitol. 2008 Jun;94(3):757-8.PMID: 18605805 [PubMed - indexed for MEDLINE]Related articles

Evaluation of the mood-stabilizing agent valproic acid as a preventative for toxoplasmosis in mice and activity against tissue cysts in mice.

Goodwin DG, Strobl J, Mitchell SM, Zajac AM, Lindsay DS.

J Parasitol. 2008 Apr;94(2):555-7.PMID: 18564764 [PubMed - indexed for MEDLINE]Related articles

Gauging the gaps in student problem-solving skills: assessment of individual and group use of problem-solving strategies using online discussions.

Anderson WL, Mitchell SM, Osgood MP.

CBE Life Sci Educ. 2008 Summer;7(2):254-62.PMID: 18519617 [PubMed - indexed for MEDLINE]Related articlesFree article

Bisulphite differential denaturation PCR for analysis of DNA methylation.

Rand KN, Mitchell SM, Clark SJ, Molloy PL.

Epigenetics. 2006 Apr-Jun;1(2):94-100. Epub 2006 Mar 7.PMID: 17998815 [PubMed - indexed for MEDLINE]Related articlesFree article

A prospective study of change in visual function in patients treated with pegylated interferon alpha for hepatitis C in the UK.

Malik NN, Sheth HG, Ackerman N, Davies N, Mitchell SM.

Br J Ophthalmol. 2008 Feb;92(2):256-8. Epub 2007 Oct 25.PMID: 17962387 [PubMed - indexed for MEDLINE]Related articles

Scriptaid and suberoylanilide hydroxamic acid are histone deacetylase inhibitors with potent anti-Toxoplasma gondii activity in vitro.

Strobl JS, Cassell M, Mitchell SM, Reilly CM, Lindsay DS.

J Parasitol. 2007 Jun;93(3):694-700.PMID: 17626366 [PubMed - indexed for MEDLINE]Related articles

Cystoisospora canis Nemeséri, 1959 (syn. Isospora canis), infections in dogs: clinical signs, pathogenesis, and reproducible clinical disease in beagle dogs fed oocysts.

Mitchell SM, Zajac AM, Charles S, Duncan RB, Lindsay DS.

J Parasitol. 2007 Apr;93(2):345-52.PMID: 17539419 [PubMed - indexed for MEDLINE]Related articles

Acute retinal necrosis: a national population-based study to assess the incidence, methods of diagnosis, treatment strategies and outcomes in the UK.

Muthiah MN, Michaelides M, Child CS, Mitchell SM.

Br J Ophthalmol. 2007 Nov;91(11):1452-5. Epub 2007 May 15.PMID: 17504853 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevention of recrudescent toxoplasmic encephalitis using ponazuril in an immunodeficient mouse model.

Mitchell SM, Zajac AM, Kennedy T, Davis W, Dubey JP, Lindsay DS.

J Eukaryot Microbiol. 2006;53 Suppl 1:S164-5. No abstract available. PMID: 17169046 [PubMed - indexed for MEDLINE]Related articles

Dynamic changes in the cervical epithelial tight junction complex and differentiation occur during cervical ripening and parturition.

Timmons BC, Mitchell SM, Gilpin C, Mahendroo MS.

Endocrinology. 2007 Mar;148(3):1278-87. Epub 2006 Nov 30.PMID: 17138657 [PubMed - indexed for MEDLINE]Related articlesFree article

A study of association between common variation in the growth hormone-chorionic somatomammotropin hormone gene cluster and adult fasting insulin in a UK Caucasian population.

Freathy RM, Mitchell SM, Knight B, Shields B, Weedon MN, Hattersley AT, Frayling TM.

J Negat Results Biomed. 2006 Nov 24;5:18.PMID: 17125497 [PubMed - indexed for MEDLINE]Related articlesFree article

Seroprevalence of Toxoplasma gondii, Sarcocystis neurona, and Encephalitozoon cuniculi in three species of lemurs from St. Catherines Island, GA, USA.

Yabsley MJ, Jordan CN, Mitchell SM, Norton TM, Lindsay DS.

Vet Parasitol. 2007 Mar 15;144(1-2):28-32. Epub 2006 Oct 18.PMID: 17052854 [PubMed - indexed for MEDLINE]Related articles

Prevalence of agglutinating antibodies to Toxoplasma gondii in striped skunks (Mephitis mephitis), opossums (Didelphis virginiana), and raccoons (Procyon lotor) from Connecticut.

Mitchell SM, Richardson DJ, Lindsay DS.

J Parasitol. 2006 Jun;92(3):664-5.PMID: 16884022 [PubMed - indexed for MEDLINE]Related articles

Evaluation of zinc salt based fixatives for preserving antigenic determinants for immunohistochemical demonstration of murine immune system cell markers.

Hicks DJ, Johnson L, Mitchell SM, Gough J, Cooley WA, La Ragione RM, Spencer YI, Wangoo A.

Biotech Histochem. 2006 Jan-Feb;81(1):23-30.PMID: 16760124 [PubMed - indexed for MEDLINE]Related articles

Buprenorphine does not affect acute murine toxoplasmosis and is recommended as an analgesic in Toxoplasma gondii studies in mice.

Lindsay DS, Kaur T, Mitchell SM, Goodwin DG, Strobl J, Dubey JP.

J Parasitol. 2005 Dec;91(6):1488-90.PMID: 16544426 [PubMed - indexed for MEDLINE]Related articles

Didanosine-induced retinopathy in adults can be reversible.

Fernando AI, Anderson OA, Holder GE, Mitchell SM.

Eye (Lond). 2006 Dec;20(12):1435-7. Epub 2006 Mar 10. No abstract available. PMID: 16531973 [PubMed - indexed for MEDLINE]Related articles

Penetration of equine leukocytes by merozoites of Sarcocystis neurona.

Lindsay DS, Mitchell SM, Yang J, Dubey JP, Gogal RM Jr, Witonsky SG.

Vet Parasitol. 2006 Jun 15;138(3-4):371-6. Epub 2006 Mar 6.PMID: 16517080 [PubMed - indexed for MEDLINE]Related articles

Bilateral panuveitis in HIV-1-infected patients with CD8 lymphocytosis.

De Silva DJ, Obi AA, Mitchell SM.

Ocul Immunol Inflamm. 2005 Jul-Aug;13(4):311-6.PMID: 16159723 [PubMed - indexed for MEDLINE]Related articles

Headloop suppression PCR and its application to selective amplification of methylated DNA sequences.

Rand KN, Ho T, Qu W, Mitchell SM, White R, Clark SJ, Molloy PL.

Nucleic Acids Res. 2005 Aug 9;33(14):e127.PMID: 16091627 [PubMed - indexed for MEDLINE]Related articlesFree article

The effects of ponazuril on development of apicomplexans in vitro.

Mitchell SM, Zajac AM, Davis WL, Kennedy TJ, Lindsay DS.

J Eukaryot Microbiol. 2005 May-Jun;52(3):231-5.PMID: 15926999 [PubMed - indexed for MEDLINE]Related articles

Survival of Toxoplasma gondii oocysts in Eastern oysters (Crassostrea virginica).

Lindsay DS, Collins MV, Mitchell SM, Wetch CN, Rosypal AC, Flick GJ, Zajac AM, Lindquist A, Dubey JP.

J Parasitol. 2004 Oct;90(5):1054-7.PMID: 15562605 [PubMed - indexed for MEDLINE]Related articles

Sarcocystis neurona (Protozoa: Apicomplexa): description of oocysts, sporocysts, sporozoites, excystation, and early development.

Lindsay DS, Mitchell SM, Vianna MC, Dubey JP.

J Parasitol. 2004 Jun;90(3):461-5.PMID: 15272465 [PubMed - indexed for MEDLINE]Related articles

Efficacy of ponazuril in vitro and in preventing and treating Toxoplasma gondii infections in mice.

Mitchell SM, Zajac AM, Davis WL, Lindsay DS.

J Parasitol. 2004 Jun;90(3):639-42.PMID: 15270113 [PubMed - indexed for MEDLINE]Related articles

Structure and function of extracellular loop 4 of the serotonin transporter as revealed by cysteine-scanning mutagenesis.

Mitchell SM, Lee E, Garcia ML, Stephan MM.

J Biol Chem. 2004 Jun 4;279(23):24089-99. Epub 2004 Mar 31.PMID: 15140876 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytomegalovirus Retinitis in infancy.

Wren SM, Fielder AR, Bethell D, Lyall EG, Tudor-Williams G, Cocker KD, Mitchell SM.

Eye (Lond). 2004 Apr;18(4):389-92. Review.PMID: 15069436 [PubMed - indexed for MEDLINE]Related articles

Mode of action of ponazuril against Toxoplasma gondii tachyzoites in cell culture.

Mitchell SM, Zajac AM, Davis WL, Lindsay DS.

J Eukaryot Microbiol. 2003;50 Suppl:689-90.PMID: 14736221 [PubMed - indexed for MEDLINE]Related articles

Sporulation and survival of Toxoplasma gondii oocysts in seawater.

Lindsay DS, Collins MV, Mitchell SM, Cole RA, Flick GJ, Wetch CN, Lindquist A, Dubey JP.

J Eukaryot Microbiol. 2003;50 Suppl:687-8.PMID: 14736220 [PubMed - indexed for MEDLINE]Related articles

Lack of support for a role of the insulin gene variable number of tandem repeats minisatellite (INS-VNTR) locus in fetal growth or type 2 diabetes-related intermediate traits in United Kingdom populations.

Mitchell SM, Hattersley AT, Knight B, Turner T, Metcalf BS, Voss LD, Davies D, McCarthy A, Wilkin TJ, Smith GD, Ben-Shlomo Y, Frayling TM.

J Clin Endocrinol Metab. 2004 Jan;89(1):310-7.PMID: 14715866 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevalence of antibodies to Neospora caninum, Sarcocystis neurona, and Toxoplasma gondii in wild horses from central Wyoming.

Dubey JP, Mitchell SM, Morrow JK, Rhyan JC, Stewart LM, Granstrom DE, Romand S, Thulliez P, Saville WJ, Lindsay DS.

J Parasitol. 2003 Aug;89(4):716-20.PMID: 14533680 [PubMed - indexed for MEDLINE]Related articles

Genetic variation in the small heterodimer partner gene and young-onset type 2 diabetes, obesity, and birth weight in U.K. subjects.

Mitchell SM, Weedon MN, Owen KR, Shields B, Wilkins-Wall B, Walker M, McCarthy MI, Frayling TM, Hattersley AT.

Diabetes. 2003 May;52(5):1276-9.PMID: 12716764 [PubMed - indexed for MEDLINE]Related articlesFree article

Reactivity against Sarcocystis neurona and Neospora by serum antibodies in healthy French horses from two farms with previous equine protozoal myeloencephalitis-like cases.

Pitel PH, Lindsay DS, Caure S, Romand S, Pronost S, Gargala G, Mitchell SM, Hary C, Thulliez P, Fortier G, Ballet JJ.

Vet Parasitol. 2003 Jan 20;111(1):1-7.PMID: 12523974 [PubMed - indexed for MEDLINE]Related articles

Successful treatment of varicella zoster virus retinitis with aggressive intravitreal and systemic antiviral therapy.

Zambarakji HJ, Obi AA, Mitchell SM.

Ocul Immunol Inflamm. 2002 Mar;10(1):41-6.PMID: 12461702 [PubMed - indexed for MEDLINE]Related articles

Prevalence of agglutinating antibodies to Sarcocystis neurona in skunks (Mephitis Mephitis), raccoons (Procyon lotor), and opossums (Didelphis Virginiana) from Connecticut.

Mitchell SM, Richardson DJ, Cheadle MA, Zajac AM, Lindsay DS.

J Parasitol. 2002 Oct;88(5):1027-9.PMID: 12435152 [PubMed - indexed for MEDLINE]Related articles

The role of transcription factors in maturity-onset diabetes of the young.

Mitchell SM, Frayling TM.

Mol Genet Metab. 2002 Sep-Oct;77(1-2):35-43. Review.PMID: 12359128 [PubMed - indexed for MEDLINE]Related articles

Rare variants identified in the HNF- 4 alpha beta-cell-specific promoter and alternative exon 1 lack biological significance in maturity onset diabetes of the young and young onset Type II diabetes.

Mitchell SM, Vaxillaire M, Thomas H, Parrizas M, Benmezroua Y, Costa A, Hansen T, Owen KR, Tuomi T, Pirie F, Ryffel GU, Ferrer J, Froguel P, Hattersley AT, Frayling TM.

Diabetologia. 2002 Sep;45(9):1344-8. Epub 2002 Jul 19.PMID: 12242469 [PubMed - indexed for MEDLINE]Related articles

A putative functional polymorphism in the IGF-I gene: association studies with type 2 diabetes, adult height, glucose tolerance, and fetal growth in U.K. populations.

Frayling TM, Hattersley AT, McCarthy A, Holly J, Mitchell SM, Gloyn AL, Owen K, Davies D, Smith GD, Ben-Shlomo Y.

Diabetes. 2002 Jul;51(7):2313-6.PMID: 12086966 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of the HNF4alpha enhancer in type 2 diabetes.

Mitchell SM, Gloyn AL, Owen KR, Hattersley AT, Frayling TM.

Mol Genet Metab. 2002 Jun;76(2):148-51.PMID: 12083813 [PubMed - indexed for MEDLINE]Related articles

New insights into heparin binding to vitronectin: studies with monoclonal antibodies.

Underwood PA, Kirkpatrick A, Mitchell SM.

Biochem J. 2002 Jul 1;365(Pt 1):57-67.PMID: 12071840 [PubMed - indexed for MEDLINE]Related articlesFree article

The pharmacokinetics of methadone following co-administration with a lamivudine/zidovudine combination tablet in opiate-dependent subjects.

Rainey PM, Friedland GH, Snidow JW, McCance-Katz EF, Mitchell SM, Andrews L, Lane B, Jatlow P.

Am J Addict. 2002 Winter;11(1):66-74.PMID: 11876585 [PubMed - indexed for MEDLINE]Related articles

Failure of accommodation in patients with HIV infection.

Westcott MC, Ward M, Mitchell SM.

Eye (Lond). 2001 Aug;15(Pt 4):474-8.PMID: 11767022 [PubMed - indexed for MEDLINE]Related articles

A distant upstream promoter of the HNF-4alpha gene connects the transcription factors involved in maturity-onset diabetes of the young.

Thomas H, Jaschkowitz K, Bulman M, Frayling TM, Mitchell SM, Roosen S, Lingott-Frieg A, Tack CJ, Ellard S, Ryffel GU, Hattersley AT.

Hum Mol Genet. 2001 Sep 15;10(19):2089-97.PMID: 11590126 [PubMed - indexed for MEDLINE]Related articlesFree article

Visual outcome after silicone oil removal and recurrent retinal detachment repair.

Flaxel CJ, Mitchell SM, Aylward GW.

Eye (Lond). 2000 Dec;14(Pt 6):834-8.PMID: 11584838 [PubMed - indexed for MEDLINE]Related articles

Electrophysiological abnormalities following intravitreal vitravene (ISIS 2922) in two patients with CMV retinitis.

Zambarakji HJ, Mitchell SM, Lightman S, Holder GE.

Br J Ophthalmol. 2001 Sep;85(9):1142. No abstract available. PMID: 11561556 [PubMed - indexed for MEDLINE]Related articlesFree article

CMVR diagnoses and progression of CD4 cell counts and HIV viral load measurements in HIV patients on HAART.

Zambarakji HJ, Newson RB, Mitchell SM.

Br J Ophthalmol. 2001 Jul;85(7):837-41.PMID: 11423459 [PubMed - indexed for MEDLINE]Related articlesFree article