PubMed

Chemokine CXCL16 Regulates Neutrophil and Macrophage Infiltration into Injured Muscle, Promoting Muscle Regeneration.

Zhang L, Ran L, Garcia GE, Wang XH, Han S, Du J, Mitch WE.

Am J Pathol. 2009 Nov 5. [Epub ahead of print]PMID: 19893053 [PubMed - as supplied by publisher]Related articles

Endogenous glucocorticoids and impaired insulin signaling are both required to stimulate muscle wasting under pathophysiological conditions in mice.

Hu Z, Wang H, Lee IH, Du J, Mitch WE.

J Clin Invest. 2009 Oct;119(10):3059-69. doi: 10.1172/JCI38770. Epub 2009 Sep 14.PMID: 19759515 [PubMed - in process]Related articlesFree article

Exercise ameliorates chronic kidney disease-induced defects in muscle protein metabolism and progenitor cell function.

Wang XH, Du J, Klein JD, Bailey JL, Mitch WE.

Kidney Int. 2009 Oct;76(7):751-9. Epub 2009 Jul 29.PMID: 19641484 [PubMed - in process]Related articles

Navigating between the Scylla and Charybdis of prescribing dietary protein for chronic kidney diseases.

Franch HA, Mitch WE.

Annu Rev Nutr. 2009;29:341-64. Review.PMID: 19575595 [PubMed - indexed for MEDLINE]Related articles

Influence of renal function and diet on acid-base status in chronic kidney disease patients.

Leal VO, Delgado AG, Leite M Jr, Mitch WE, Mafra D.

J Ren Nutr. 2009 Mar;19(2):178-82.PMID: 19218046 [PubMed - indexed for MEDLINE]Related articles

IL-6 and serum amyloid A synergy mediates angiotensin II-induced muscle wasting.

Zhang L, Du J, Hu Z, Han G, Delafontaine P, Garcia G, Mitch WE.

J Am Soc Nephrol. 2009 Mar;20(3):604-12. Epub 2009 Jan 21.PMID: 19158350 [PubMed - indexed for MEDLINE]Related articles

OPPORTUNITY: a randomized clinical trial of growth hormone on outcome in hemodialysis patients.

Kopple JD, Cheung AK, Christiansen JS, Djurhuus CB, El Nahas M, Feldt-Rasmussen B, Lange M, Mitch WE, Wanner C, Wiedemann J, Ikizler TA.

Clin J Am Soc Nephrol. 2008 Nov;3(6):1741-51.PMID: 18945992 [PubMed - indexed for MEDLINE]Related articlesFree article

Ubiquitin, proteasomes and proteolytic mechanisms activated by kidney disease.

Rajan V, Mitch WE.

Biochim Biophys Acta. 2008 Dec;1782(12):795-9. Epub 2008 Aug 5. Review.PMID: 18723090 [PubMed - indexed for MEDLINE]Related articles

Cachexia: a new definition.

Evans WJ, Morley JE, Argilés J, Bales C, Baracos V, Guttridge D, Jatoi A, Kalantar-Zadeh K, Lochs H, Mantovani G, Marks D, Mitch WE, Muscaritoli M, Najand A, Ponikowski P, Rossi Fanelli F, Schambelan M, Schols A, Schuster M, Thomas D, Wolfe R, Anker SD.

Clin Nutr. 2008 Dec;27(6):793-9. Epub 2008 Aug 21.PMID: 18718696 [PubMed - indexed for MEDLINE]Related articles

Ghrelin treatment of chronic kidney disease: improvements in lean body mass and cytokine profile.

Deboer MD, Zhu X, Levasseur PR, Inui A, Hu Z, Han G, Mitch WE, Taylor JE, Halem HA, Dong JZ, Datta R, Culler MD, Marks DL.

Endocrinology. 2008 Feb;149(2):827-35. Epub 2007 Nov 26.PMID: 18039782 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscle wasting in chronic kidney disease: the role of the ubiquitin proteasome system and its clinical impact.

Rajan VR, Mitch WE.

Pediatr Nephrol. 2008 Apr;23(4):527-35. Epub 2007 Nov 7. Review.PMID: 17987322 [PubMed - indexed for MEDLINE]Related articlesFree article

Risk scores for predicting outcomes in patients with type 2 diabetes and nephropathy: the RENAAL study.

Keane WF, Zhang Z, Lyle PA, Cooper ME, de Zeeuw D, Grunfeld JP, Lash JP, McGill JB, Mitch WE, Remuzzi G, Shahinfar S, Snapinn SM, Toto R, Brenner BM; RENAAL Study Investigators.

Clin J Am Soc Nephrol. 2006 Jul;1(4):761-7. Epub 2006 May 17.PMID: 17699284 [PubMed - indexed for MEDLINE]Related articlesFree article

PTEN expression contributes to the regulation of muscle protein degradation in diabetes.

Hu Z, Lee IH, Wang X, Sheng H, Zhang L, Du J, Mitch WE.

Diabetes. 2007 Oct;56(10):2449-56. Epub 2007 Jul 10.PMID: 17623817 [PubMed - indexed for MEDLINE]Related articlesFree article

Malnutrition is an unusual cause of decreased muscle mass in chronic kidney disease.

Mitch WE.

J Ren Nutr. 2007 Jan;17(1):66-9.PMID: 17198936 [PubMed - indexed for MEDLINE]Related articles

Evidence that C-reactive protein or IL-6 are not surrogates for all inflammatory cardiovascular risk factors in hemodialysis patients.

Kaysen GA, Levin NW, Mitch WE, Chapman AL, Kubala L, Eiserich JP.

Blood Purif. 2006;24(5-6):508-16. Epub 2006 Oct 23.PMID: 17077623 [PubMed - indexed for MEDLINE]Related articles

Development of a diagnostic method for detecting increased muscle protein degradation in patients with catabolic conditions.

Workeneh BT, Rondon-Berrios H, Zhang L, Hu Z, Ayehu G, Ferrando A, Kopple JD, Wang H, Storer T, Fournier M, Lee SW, Du J, Mitch WE.

J Am Soc Nephrol. 2006 Nov;17(11):3233-9. Epub 2006 Sep 27.PMID: 17005936 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue-specific regulation of ubiquitin (UbC) transcription by glucocorticoids: in vivo and in vitro analyses.

Marinovic AC, Zheng B, Mitch WE, Price SR.

Am J Physiol Renal Physiol. 2007 Feb;292(2):F660-6. Epub 2006 Sep 5.PMID: 16954342 [PubMed - indexed for MEDLINE]Related articlesFree article

Is cystatin C more effective than creatinine in predicting adverse cardiovascular outcomes in elderly people?

Mandayam S, Mitch WE.

Nat Clin Pract Nephrol. 2005 Nov;1(1):8-9. No abstract available. PMID: 16932354 [PubMed]Related articles

Effect of bicarbonate on muscle protein in patients receiving hemodialysis.

Löfberg E, Gutierrez A, Anderstam B, Wernerman J, Bergström J, Price SR, Mitch WE, Alvestrand A.

Am J Kidney Dis. 2006 Sep;48(3):419-29.PMID: 16931215 [PubMed - indexed for MEDLINE]Related articles

Proteolytic mechanisms, not malnutrition, cause loss of muscle mass in kidney failure.

Mitch WE.

J Ren Nutr. 2006 Jul;16(3):208-11. Review.PMID: 16825021 [PubMed - indexed for MEDLINE]Related articles

Insulin resistance accelerates muscle protein degradation: Activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling.

Wang X, Hu Z, Hu J, Du J, Mitch WE.

Endocrinology. 2006 Sep;147(9):4160-8. Epub 2006 Jun 15.PMID: 16777975 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein degradation by the ubiquitin-proteasome pathway in normal and disease states.

Lecker SH, Goldberg AL, Mitch WE.

J Am Soc Nephrol. 2006 Jul;17(7):1807-19. Epub 2006 May 31. Review. No abstract available. PMID: 16738015 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic and clinical consequences of metabolic acidosis.

Mitch WE.

J Nephrol. 2006 Mar-Apr;19 Suppl 9:S70-5. Review.PMID: 16736444 [PubMed - indexed for MEDLINE]Related articles

Regulation of epithelial sodium channels by the ubiquitin-proteasome proteolytic pathway.

Malik B, Price SR, Mitch WE, Yue Q, Eaton DC.

Am J Physiol Renal Physiol. 2006 Jun;290(6):F1285-94. Review.PMID: 16682484 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic kidney disease causes defects in signaling through the insulin receptor substrate/phosphatidylinositol 3-kinase/Akt pathway: implications for muscle atrophy.

Bailey JL, Zheng B, Hu Z, Price SR, Mitch WE.

J Am Soc Nephrol. 2006 May;17(5):1388-94. Epub 2006 Apr 12.PMID: 16611720 [PubMed - indexed for MEDLINE]Related articlesFree article

Dietary protein restriction benefits patients with chronic kidney disease.

Mandayam S, Mitch WE.

Nephrology (Carlton). 2006 Feb;11(1):53-7. Review.PMID: 16509933 [PubMed - indexed for MEDLINE]Related articles

Cellular signals activating muscle proteolysis in chronic kidney disease: a two-stage process.

Du J, Hu Z, Mitch WE.

Int J Biochem Cell Biol. 2005 Oct;37(10):2147-55. Review.PMID: 15982920 [PubMed - indexed for MEDLINE]Related articles

Cachexia in chronic kidney disease: a link to defective central nervous system control of appetite.

Mitch WE.

J Clin Invest. 2005 Jun;115(6):1476-8.PMID: 15931387 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of pathways controlling muscle protein metabolism in uremia and other catabolic conditions.

Du J, Mitch WE.

Curr Opin Nephrol Hypertens. 2005 Jul;14(4):378-82. Review.PMID: 15931008 [PubMed - indexed for MEDLINE]Related articles

Role of Nedd4-2 and polyubiquitination in epithelial sodium channel degradation in untransfected renal A6 cells expressing endogenous ENaC subunits.

Malik B, Yue Q, Yue G, Chen XJ, Price SR, Mitch WE, Eaton DC.

Am J Physiol Renal Physiol. 2005 Jul;289(1):F107-16. Epub 2005 Mar 15.PMID: 15769939 [PubMed - indexed for MEDLINE]Related articlesFree article

A report with consensus statements of the International Society of Nephrology 2004 Consensus Workshop on Prevention of Progression of Renal Disease, Hong Kong, June 29, 2004.

Li PK, Weening JJ, Dirks J, Lui SL, Szeto CC, Tang S, Atkins RC, Mitch WE, Chow KM, D'Amico G, Freedman BI, Harris DC, Hooi LS, Jong PE, Kincaid-Smith P, Lai KN, Lee E, Li FK, Lin SY, Lo WK, Mani MK, Mathew T, Murakami M, Qian JQ, Ramirez S, Reiser T, Tomino Y, Tong MK, Tsang WK, Tungsanga K, Wang H, Wong AK, Wong KM, Yang WC, Zeeuw D, Yu AW, Remuzzi G; Participants of ISN Consensus Workshop on Prevention of Progression of Renal Disease.

Kidney Int Suppl. 2005 Apr;(94):S2-7. Review.PMID: 15752234 [PubMed - indexed for MEDLINE]Related articles

Beneficial responses to modified diets in treating patients with chronic kidney disease.

Mitch WE.

Kidney Int Suppl. 2005 Apr;(94):S133-5. Review.PMID: 15752230 [PubMed - indexed for MEDLINE]Related articles

Molecular mechanisms activating muscle protein degradation in chronic kidney disease and other catabolic conditions.

Du J, Hu Z, Mitch WE.

Eur J Clin Invest. 2005 Mar;35(3):157-63. Review.PMID: 15733069 [PubMed - indexed for MEDLINE]Related articles

2004 Presidential Address: An evaluation of progress toward goals.

Mitch WE.

J Am Soc Nephrol. 2005 Mar;16(3):576-82. Epub 2005 Jan 26. No abstract available. PMID: 15677306 [PubMed - indexed for MEDLINE]Related articlesFree article

The evidence against malnutrition as a prominent problem for chronic dialysis patients.

Ahuja TS, Mitch WE.

Semin Dial. 2004 Nov-Dec;17(6):427-31. Review.PMID: 15660572 [PubMed - indexed for MEDLINE]Related articles

Muscle-specific expression of IGF-1 blocks angiotensin II-induced skeletal muscle wasting.

Song YH, Li Y, Du J, Mitch WE, Rosenthal N, Delafontaine P.

J Clin Invest. 2005 Feb;115(2):451-8.PMID: 15650772 [PubMed - indexed for MEDLINE]Related articlesFree article

Strategies for suppressing muscle atrophy in chronic kidney disease: mechanisms activating distinct proteolytic systems.

Mitch WE, Hu Z, Lee SW, Du J.

J Ren Nutr. 2005 Jan;15(1):23-7.PMID: 15648002 [PubMed - indexed for MEDLINE]Related articles

The dilemma of diagnosing the cause of hypernatraemia: drinking habits vs diabetes insipidus.

Workeneh B, Balakumaran A, Bichet DG, Mitch WE.

Nephrol Dial Transplant. 2004 Dec;19(12):3165-7. No abstract available. PMID: 15575005 [PubMed - indexed for MEDLINE]Related articlesFree article

Treating diabetic nephropathy--are there only economic issues?

Mitch WE.

N Engl J Med. 2004 Nov 4;351(19):1934-6. Epub 2004 Oct 31. No abstract available. PMID: 15516698 [PubMed - indexed for MEDLINE]Related articles

Protein catabolism in chronic uremia: is it due to malnutrition?

Ahuja TS, Mitch WE.

Arch Immunol Ther Exp (Warsz). 2004 Sep-Oct;52(5):326-31. Review.PMID: 15507873 [PubMed - indexed for MEDLINE]Related articles

Cellular mechanisms causing loss of muscle mass in kidney disease.

Mitch WE, Du J.

Semin Nephrol. 2004 Sep;24(5):484-7. Review.PMID: 15490416 [PubMed - indexed for MEDLINE]Related articles

Detecting and managing patients with type 2 diabetic kidney disease: proteinuria and cardiovascular disease.

Mitch WE, Shahinfar S, Dickson TZ, de Zeeuw D, Zhang Z.

Kidney Int Suppl. 2004 Nov;(92):S97-8. Review.PMID: 15485428 [PubMed - indexed for MEDLINE]Related articles

Albuminuria, a therapeutic target for cardiovascular protection in type 2 diabetic patients with nephropathy.

de Zeeuw D, Remuzzi G, Parving HH, Keane WF, Zhang Z, Shahinfar S, Snapinn S, Cooper ME, Mitch WE, Brenner BM.

Circulation. 2004 Aug 24;110(8):921-7. Epub 2004 Aug 9.PMID: 15302780 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of muscle protein degradation: coordinated control of apoptotic and ubiquitin-proteasome systems by phosphatidylinositol 3 kinase.

Lee SW, Dai G, Hu Z, Wang X, Du J, Mitch WE.

J Am Soc Nephrol. 2004 Jun;15(6):1537-45.PMID: 15153564 [PubMed - indexed for MEDLINE]Related articlesFree article

Proteinuria, a target for renoprotection in patients with type 2 diabetic nephropathy: lessons from RENAAL.

de Zeeuw D, Remuzzi G, Parving HH, Keane WF, Zhang Z, Shahinfar S, Snapinn S, Cooper ME, Mitch WE, Brenner BM.

Kidney Int. 2004 Jun;65(6):2309-20.PMID: 15149345 [PubMed - indexed for MEDLINE]Related articles

Inflammation and reduced albumin synthesis associated with stable decline in serum albumin in hemodialysis patients.

Kaysen GA, Dubin JA, Müller HG, Rosales L, Levin NW, Mitch WE; HEMO Study Group NIDDK.

Kidney Int. 2004 Apr;65(4):1408-15.PMID: 15086482 [PubMed - indexed for MEDLINE]Related articles

Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression.

Lecker SH, Jagoe RT, Gilbert A, Gomes M, Baracos V, Bailey J, Price SR, Mitch WE, Goldberg AL.

FASEB J. 2004 Jan;18(1):39-51.PMID: 14718385 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions.

Du J, Wang X, Miereles C, Bailey JL, Debigare R, Zheng B, Price SR, Mitch WE.

J Clin Invest. 2004 Jan;113(1):115-23.PMID: 14702115 [PubMed - indexed for MEDLINE]Related articlesFree article

Diets for patients with chronic kidney disease, still worth prescribing.

Mitch WE, Remuzzi G.

J Am Soc Nephrol. 2004 Jan;15(1):234-7. Review. No abstract available. PMID: 14694178 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension.

Landmesser U, Dikalov S, Price SR, McCann L, Fukai T, Holland SM, Mitch WE, Harrison DG.

J Clin Invest. 2003 Apr;111(8):1201-9.PMID: 12697739 [PubMed - indexed for MEDLINE]Related articlesFree article