PubMed

Activated polyamine catabolism leads to low cholesterol levels by enhancing bile acid synthesis.

Pirinen E, Gylling H, Itkonen P, Yaluri N, Heikkinen S, Pietilä M, Kuulasmaa T, Tusa M, Cerrada-Gimenez M, Pihlajamäki J, Alhonen L, Jänne J, Miettinen TA, Laakso M.

Amino Acids. 2009 Dec 3. [Epub ahead of print]PMID: 19956992 [PubMed - as supplied by publisher]Related articles

Very high plant stanol intake and serum plant stanols and non-cholesterol sterols.

Gylling H, Hallikainen M, Nissinen MJ, Simonen P, Miettinen TA.

Eur J Nutr. 2009 Sep 23. [Epub ahead of print]PMID: 19774436 [PubMed - as supplied by publisher]Related articles

The effect of a very high daily plant stanol ester intake on serum lipids, carotenoids, and fat-soluble vitamins.

Gylling H, Hallikainen M, Nissinen MJ, Miettinen TA.

Clin Nutr. 2009 Aug 25. [Epub ahead of print]PMID: 19709787 [PubMed - as supplied by publisher]Related articles

Applicability of non-cholesterol sterols in predicting response in cholesterol metabolism to simvastatin and fluvastatin treatment among hypercholesterolemic men.

Nissinen MJ, Miettinen TE, Gylling H, Miettinen TA.

Nutr Metab Cardiovasc Dis. 2009 Aug 18. [Epub ahead of print]PMID: 19695854 [PubMed - as supplied by publisher]Related articles

Cholesterol, non-cholesterol sterols and bile acids in paediatric gallstones.

Koivusalo AI, Pakarinen MP, Sittiwet C, Gylling H, Miettinen TA, Miettinen TE, Nissinen MJ.

Dig Liver Dis. 2009 Jul 23. [Epub ahead of print]PMID: 19632165 [PubMed - as supplied by publisher]Related articles

Explaining the obesity paradox: cardiovascular risk, weight change, and mortality during long-term follow-up in men.

Strandberg TE, Strandberg AY, Salomaa VV, Pitkälä KH, Tilvis RS, Sirola J, Miettinen TA.

Eur Heart J. 2009 Jul;30(14):1720-7. Epub 2009 May 9.PMID: 19429917 [PubMed - indexed for MEDLINE]Related articles

The metabolism of plant sterols is disturbed in postmenopausal women with coronary artery disease.

Gylling H, Hallikainen M, Rajaratnam RA, Simonen P, Pihlajamäki J, Laakso M, Miettinen TA.

Metabolism. 2009 Mar;58(3):401-7.PMID: 19217458 [PubMed - indexed for MEDLINE]Related articles

Twenty-one year tracking of serum non-cholesterol sterols. The Cardiovascular Risk in Young Finns study.

Miettinen TA, Hallikainen M, Raitakari OT, Viikari J, Gylling H.

Nutr Metab Cardiovasc Dis. 2009 Oct;19(8):525-31. Epub 2009 Jan 29.PMID: 19185477 [PubMed - in process]Related articles

The effects of statins and sitosterols: benefit or not?

Miettinen TA, Gylling H.

Curr Atheroscler Rep. 2009 Jan;11(1):23-7.PMID: 19080724 [PubMed - indexed for MEDLINE]Related articles

Long-term consumption of plant stanol and sterol esters, vascular function and genetic regulation.

Gylling H, Hallikainen M, Raitakari OT, Laakso M, Vartiainen E, Salo P, Korpelainen V, Sundvall J, Miettinen TA.

Br J Nutr. 2009 Jun;101(11):1688-95. Epub 2008 Nov 19.PMID: 19019257 [PubMed - indexed for MEDLINE]Related articles

Plant stanol ester spreads as components of a balanced diet for pregnant and breast-feeding women: evaluation of clinical safety.

Laitinen K, Isolauri E, Kaipiainen L, Gylling H, Miettinen TA.

Br J Nutr. 2009 Jun;101(12):1797-804. Epub 2008 Nov 19.PMID: 19017423 [PubMed - indexed for MEDLINE]Related articles

Serum sterols in patients with primary biliary cirrhosis and acute liver failure before and after liver transplantation.

Nikkilä K, Nissinen MJ, Gylling H, Isoniemi H, Miettinen TA.

J Hepatol. 2008 Dec;49(6):936-45. Epub 2008 Sep 26.PMID: 18926587 [PubMed - indexed for MEDLINE]Related articles

The effect of smoking in midlife on health-related quality of life in old age: a 26-year prospective study.

Strandberg AY, Strandberg TE, Pitkälä K, Salomaa VV, Tilvis RS, Miettinen TA.

Arch Intern Med. 2008 Oct 13;168(18):1968-74.PMID: 18852397 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphism of the hepatic influx transporter organic anion transporting polypeptide 1B1 is associated with increased cholesterol synthesis rate.

Pasanen MK, Miettinen TA, Gylling H, Neuvonen PJ, Niemi M.

Pharmacogenet Genomics. 2008 Oct;18(10):921-6.PMID: 18794729 [PubMed - indexed for MEDLINE]Related articles

Adolescent cholesterol metabolism predicts coronary risk factors at middle age: the Cardiovascular Risk in Young Finns Study.

Miettinen TA, Gylling H, Raitakari OT, Hallikainen M, Viikari J.

Transl Res. 2008 May;151(5):260-6. Epub 2008 Mar 27.PMID: 18433708 [PubMed - indexed for MEDLINE]Related articles

Vascular effects of diets, especially plant sterol ester consumption.

Miettinen TA, Gylling H.

J Am Coll Cardiol. 2008 Apr 22;51(16):1562-3. No abstract available. PMID: 18420098 [PubMed - indexed for MEDLINE]Related articles

Effects of dietary cholesterol and fat on serum non-cholesterol sterols according to different apolipoprotein E subgroups among healthy men.

Nissinen MJ, Gylling H, Miettinen TA.

Br J Nutr. 2008 Aug;100(2):373-9. Epub 2008 Feb 18.PMID: 18279555 [PubMed - indexed for MEDLINE]Related articles

Plant stanol ester consumption and arterial elasticity and endothelial function.

Raitakari OT, Salo P, Gylling H, Miettinen TA.

Br J Nutr. 2008 Sep;100(3):603-8. Epub 2008 Feb 18.PMID: 18279553 [PubMed - indexed for MEDLINE]Related articles

Synthesis and absorption of cholesterol in Finnish boys by serum non-cholesterol sterols: the cardiovascular risk in Young Finns Study.

Miettinen TA, Gylling H, Viikari J, Lehtimäki T, Raitakari OT.

Atherosclerosis. 2008 Sep;200(1):177-83. Epub 2008 Feb 21.PMID: 18178213 [PubMed - indexed for MEDLINE]Related articles

Effects of plant stanol esters on serum cholesterol concentrations, relative markers of cholesterol metabolism and endothelial function in type 1 diabetes.

Hallikainen M, Lyyra-Laitinen T, Laitinen T, Moilanen L, Miettinen TA, Gylling H.

Atherosclerosis. 2008 Aug;199(2):432-9. Epub 2007 Dec 11.PMID: 18062976 [PubMed - indexed for MEDLINE]Related articles

The association between weight gain up to midlife, 30-year mortality, and quality of life in older men.

Strandberg TE, Strandberg A, Salomaa VV, Pitkälä K, Tilvis RS, Miettinen TA.

Arch Intern Med. 2007 Nov 12;167(20):2260-1. No abstract available. PMID: 17998501 [PubMed - indexed for MEDLINE]Related articles

The validity of serum squalene and non-cholesterol sterols as surrogate markers of cholesterol synthesis and absorption in type 2 diabetes.

Simonen P, Gylling H, Miettinen TA.

Atherosclerosis. 2008 Apr;197(2):883-8. Epub 2007 Sep 17.PMID: 17875306 [PubMed - indexed for MEDLINE]Related articles

Responses of surrogate markers of cholesterol absorption and synthesis to changes in cholesterol metabolism during various amounts of fat and cholesterol feeding among healthy men.

Nissinen MJ, Gylling H, Miettinen TA.

Br J Nutr. 2008 Feb;99(2):370-8. Epub 2007 Aug 15.PMID: 17697430 [PubMed - indexed for MEDLINE]Related articles

Serum adipokines are associated with cholesterol metabolism in the metabolic syndrome.

Hallikainen M, Kolehmainen M, Schwab U, Laaksonen DE, Niskanen L, Rauramaa R, Pihlajamäki J, Uusitupa M, Miettinen TA, Gylling H.

Clin Chim Acta. 2007 Aug;383(1-2):126-32. Epub 2007 May 18.PMID: 17573060 [PubMed - indexed for MEDLINE]Related articles

Respective hydrolysis and esterification of esterified and free plant stanols occur rapidly in human intestine after their duodenal infusion in triacyl- or diacylglycerol.

Nissinen MJ, Vuoristo M, Gylling H, Miettinen TA.

Lipids. 2007 Jul;42(7):603-12. Epub 2007 Jun 6.PMID: 17551763 [PubMed - indexed for MEDLINE]Related articles

Cholesterol synthesis prevails over absorption in metabolic syndrome.

Gylling H, Hallikainen M, Kolehmainen M, Toppinen L, Pihlajamäki J, Mykkänen H, Agren JJ, Rauramaa R, Laakso M, Miettinen TA.

Transl Res. 2007 Jun;149(6):310-6. Epub 2007 May 23.PMID: 17543849 [PubMed - indexed for MEDLINE]Related articles

Alcoholic beverage preference, 29-year mortality, and quality of life in men in old age.

Strandberg TE, Strandberg AY, Salomaa VV, Pitkälä K, Tilvis RS, Miettinen TA.

J Gerontol A Biol Sci Med Sci. 2007 Feb;62(2):213-8.PMID: 17339649 [PubMed - indexed for MEDLINE]Related articles

Chocolate, well-being and health among elderly men.

Strandberg TE, Strandberg AY, Pitkälä K, Salomaa VV, Tilvis RS, Miettinen TA.

Eur J Clin Nutr. 2008 Feb;62(2):247-53. Epub 2007 Feb 28.PMID: 17327862 [PubMed - indexed for MEDLINE]Related articles

Blood glucose and the metabolism of cholesterol in coronary patients with and without simvastatin treatment.

Miettinen TA, Gylling H; Subgroup analysis of Scandinavian Simvastatin Survival Study (4S).

Clin Chim Acta. 2007 Apr;379(1-2):53-8. Epub 2006 Dec 22.PMID: 17258182 [PubMed - indexed for MEDLINE]Related articles

Interaction between cholesterol and glucose metabolism during dietary carbohydrate modification in subjects with the metabolic syndrome.

Hallikainen M, Toppinen L, Mykkänen H, Agren JJ, Laaksonen DE, Miettinen TA, Niskanen L, Poutanen KS, Gylling H.

Am J Clin Nutr. 2006 Dec;84(6):1385-92.PMID: 17158421 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiovascular risk in midlife and psychological well-being among older men.

Strandberg TE, Strandberg AY, Pitkälä KH, Salomaa VV, Tilvis RS, Miettinen TA.

Arch Intern Med. 2006 Nov 13;166(20):2266-71.PMID: 17101946 [PubMed - indexed for MEDLINE]Related articlesFree article

Markers of absorption and synthesis of cholesterol in men with type 1 diabetes.

Gylling H, Laaksonen DE, Atalay M, Hallikainen M, Niskanen L, Miettinen TA.

Diabetes Metab Res Rev. 2007 Jul;23(5):372-7.PMID: 17080398 [PubMed - indexed for MEDLINE]Related articles

Cholesterol absorption and synthesis in children with type 1 diabetes.

Järvisalo M, Raitakari O, Gylling H, Miettinen TA.

Diabetes Care. 2006 Oct;29(10):2300-4.PMID: 17003310 [PubMed - indexed for MEDLINE]Related articlesFree article

Cholesterol metabolism and non-cholesterol sterol distribution in lipoproteins of type 1 diabetes: the effect of improved glycemic control.

Sittiwet C, Gylling H, Hallikainen M, Pihlajamäki J, Moilanen L, Laaksonen DE, Niskanen L, Agren JJ, Laakso M, Miettinen TA.

Atherosclerosis. 2007 Oct;194(2):465-72. Epub 2006 Sep 25.PMID: 16996519 [PubMed - indexed for MEDLINE]Related articles

The distribution of squalene and non-cholesterol sterols in lipoproteins in type 2 diabetes.

Simonen PP, Gylling H, Miettinen TA.

Atherosclerosis. 2007 Sep;194(1):222-9. Epub 2006 Sep 11.PMID: 16963050 [PubMed - indexed for MEDLINE]Related articles

Effects of plant stanol esters supplied in a fat free milieu by pastilles on cholesterol metabolism in colectomized human subjects.

Nissinen MJ, Gylling H, Miettinen TA.

Nutr Metab Cardiovasc Dis. 2006 Sep;16(6):426-35. Epub 2005 Nov 28.PMID: 16935701 [PubMed - indexed for MEDLINE]Related articles

Cholesterol and glucose metabolism and recurrent cardiovascular events among the elderly: a prospective study.

Strandberg TE, Tilvis RS, Pitkala KH, Miettinen TA.

J Am Coll Cardiol. 2006 Aug 15;48(4):708-14. Epub 2006 Jul 24.PMID: 16904538 [PubMed - indexed for MEDLINE]Related articles

Visceral obesity is associated with high levels of serum squalene.

Peltola P, Pihlajamäki J, Koutnikova H, Ruotsalainen E, Salmenniemi U, Vauhkonen I, Kainulainen S, Gylling H, Miettinen TA, Auwerx J, Laakso M.

Obesity (Silver Spring). 2006 Jul;14(7):1155-63.PMID: 16899796 [PubMed - indexed for MEDLINE]Related articles

Postprandial behavior of plasma squalene and non-cholesterol sterols in men with varying cholesterol absorption.

Hallikainen M, Vidgren H, Agren JJ, Kiviniemi V, Miettinen TA, Gylling H.

Clin Chim Acta. 2006 Dec;374(1-2):63-8. Epub 2006 May 25.PMID: 16814761 [PubMed - indexed for MEDLINE]Related articles

Plant stanol and sterol esters in prevention of cardiovascular diseases: a review.

Miettinen TA, Gylling H.

Int J Clin Pharmacol Ther. 2006 Jun;44(6):247-50. Review.PMID: 16800096 [PubMed - indexed for MEDLINE]Related articles

Changes in serum level and metabolism of cholesterol with plant stanol esters in postmenopausal women with and without coronary artery disease.

Gylling H, Rajaratnam RA, Vartiainen E, Puska P, Miettinen TA.

Menopause. 2006 Mar-Apr;13(2):286-93.PMID: 16645542 [PubMed - indexed for MEDLINE]Related articles

Drug-induced effects on cholesterol catabolism and bile acids.

Gylling H, Miettinen TA.

Curr Opin Investig Drugs. 2006 Mar;7(3):214-8. Review.PMID: 16555681 [PubMed - indexed for MEDLINE]Related articles

Altered hepatic lipid status and apolipoprotein A-I metabolism in mice lacking phospholipid transfer protein.

Siggins S, Bykov I, Hermansson M, Somerharju P, Lindros K, Miettinen TA, Jauhiainen M, Olkkonen VM, Ehnholm C.

Atherosclerosis. 2007 Jan;190(1):114-23. Epub 2006 Mar 22.PMID: 16554055 [PubMed - indexed for MEDLINE]Related articles

Serum noncholesterol sterols in children with heterozygous familial hypercholesterolemia undergoing pravastatin therapy.

Hedman M, Miettinen TA, Gylling H, Ketomäki A, Antikainen M.

J Pediatr. 2006 Feb;148(2):241-6.PMID: 16492436 [PubMed - indexed for MEDLINE]Related articles

Cholesterol absorption and synthesis in pediatric kidney, liver, and heart transplant recipients.

Siirtola A, Ketomäki A, Miettinen TA, Gylling H, Lehtimäki T, Holmberg C, Salo MK, Antikainen M.

Transplantation. 2006 Feb 15;81(3):327-34.PMID: 16477216 [PubMed - indexed for MEDLINE]Related articles

Liver transplantation in a patient with sitosterolemia and cirrhosis.

Miettinen TA, Klett EL, Gylling H, Isoniemi H, Patel SB.

Gastroenterology. 2006 Feb;130(2):542-7.PMID: 16472606 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelial function in hypercholesterolemic subjects: Effects of plant stanol and sterol esters.

Hallikainen M, Lyyra-Laitinen T, Laitinen T, Agren JJ, Pihlajamäki J, Rauramaa R, Miettinen TA, Gylling H.

Atherosclerosis. 2006 Oct;188(2):425-32. Epub 2005 Dec 28.PMID: 16386259 [PubMed - indexed for MEDLINE]Related articles

Postprandial lipemic response and lipoprotein composition in subjects with low or high cholesterol absorption efficiency.

Agren JJ, Hallikainen M, Vidgren H, Miettinen TA, Gylling H.

Clin Chim Acta. 2006 Apr;366(1-2):309-15. Epub 2005 Dec 20.PMID: 16364276 [PubMed - indexed for MEDLINE]Related articles

Cholesterol absorption: influence of body weight and the role of plant sterols.

Gylling H, Miettinen TA.

Curr Atheroscler Rep. 2005 Nov;7(6):466-71. Review.PMID: 16256005 [PubMed - indexed for MEDLINE]Related articles

Ester percentages of plant sterols and cholesterol in chylomicrons and VLDL of humans with low and high sterol absorption.

Gylling HK, Hallikainen M, Vidgren H, Agren J, Miettinen TA.

Atherosclerosis. 2006 Jul;187(1):150-2. Epub 2005 Oct 3.PMID: 16207489 [PubMed - indexed for MEDLINE]Related articles