PubMed

Recessive Mutations of the Gene TRPM1 Abrogate ON Bipolar Cell Function and Cause Complete Congenital Stationary Night Blindness in Humans.

Li Z, Sergouniotis PI, Michaelides M, Mackay DS, Wright GA, Devery S, Moore AT, Holder GE, Robson AG, Webster AR.

Am J Hum Genet. 2009 Nov;85(5):711-9. Epub 2009 Oct 29.PMID: 19878917 [PubMed - in process]Related articles

A Randomized Controlled Trial Comparing Everting Sutures with Everting Sutures and a Lateral Tarsal Strip for Involutional Entropion.

Scheepers MA, Singh R, James N, Zuercher D, Gibson A, Catey B, Fong K, Michaelides M, Olver J.

Ophthalmology. 2009 Oct 27. [Epub ahead of print]PMID: 19875173 [PubMed - as supplied by publisher]Related articles

Dopamine D4 receptor (D4R) deletion in mice does not affect operant responding for food or cocaine.

Thanos PK, Habibi R, Michaelides M, Patel UB, Suchland K, Anderson BJ, Robinson JK, Wang GJ, Grandy DK, Volkow ND.

Behav Brain Res. 2009 Oct 22. [Epub ahead of print]PMID: 19853629 [PubMed - as supplied by publisher]Related articles

CT and MRI of intraperitoneal splenosis.

Tsitouridis I, Michaelides M, Sotiriadis C, Arvaniti M.

Diagn Interv Radiol. 2009 Oct 19. doi: 10.4261/1305-3825.DIR.1855-08.1. [Epub ahead of print]PMID: 19838993 [PubMed - as supplied by publisher]Related articlesFree article

Renal emphysema in diabetic patients: CT evaluation.

Tsitouridis I, Michaelides M, Sidiropoulos D, Arvanity M.

Diagn Interv Radiol. 2009 Oct 19. doi: 10.4261/1305-3825.DIR.2130-08.1. [Epub ahead of print]PMID: 19838984 [PubMed - as supplied by publisher]Related articlesFree article

Dissociation between spontaneously hypertensive (SHR) and Wistar-Kyoto (WKY) rats in baseline performance and methylphenidate response on measures of attention, impulsivity and hyperactivity in a Visual Stimulus Position Discrimination Task.

Thanos PK, Ivanov I, Robinson JK, Michaelides M, Wang GJ, Swanson JM, Newcorn JH, Volkow ND.

Pharmacol Biochem Behav. 2009 Oct 8. [Epub ahead of print]PMID: 19818805 [PubMed - as supplied by publisher]Related articles

Novel Mutations and Electrophysiologic Findings in RGS9- andR9AP-Associated Retinal Dysfunction (Bradyopsia).

Michaelides M, Li Z, Rana NA, Richardson EC, Hykin PG, Moore AT, Holder GE, Webster AR.

Ophthalmology. 2009 Oct 7. [Epub ahead of print]PMID: 19818506 [PubMed - as supplied by publisher]Related articles

Intrahepatic portosystemic venous shunts: radiological evaluation.

Tsitouridis I, Sotiriadis C, Michaelides M, Dimarelos V, Tsitouridis K, Stratilati S.

Diagn Interv Radiol. 2009 Sep;15(3):182-7.PMID: 19728264 [PubMed - in process]Related articlesFree article

Endotracheal and tracheostomy tube-related complications: imaging with three-dimensional spiral computed tomography.

Tsitouridis I, Michaelides M, Dimarelos V, Arvaniti M.

Hippokratia. 2009 Apr;13(2):97-100.PMID: 19561779 [PubMed - in process]Related articlesFree article

Blue cone monochromacy: causative mutations and associated phenotypes.

Gardner JC, Michaelides M, Holder GE, Kanuga N, Webb TR, Mollon JD, Moore AT, Hardcastle AJ.

Mol Vis. 2009;15:876-84. Epub 2009 May 1.PMID: 19421413 [PubMed - indexed for MEDLINE]Related articlesFree article

Sonographic evaluation of epignathus.

Tsitouridis I, Sidiropoulos D, Michaelides M.

Hippokratia. 2009 Jan;13(1):55-7.PMID: 19240824 [PubMed - in process]Related articlesFree article

Mutations in CNNM4 cause Jalili syndrome, consisting of autosomal-recessive cone-rod dystrophy and amelogenesis imperfecta.

Parry DA, Mighell AJ, El-Sayed W, Shore RC, Jalili IK, Dollfus H, Bloch-Zupan A, Carlos R, Carr IM, Downey LM, Blain KM, Mansfield DC, Shahrabi M, Heidari M, Aref P, Abbasi M, Michaelides M, Moore AT, Kirkham J, Inglehearn CF.

Am J Hum Genet. 2009 Feb;84(2):266-73. Epub 2009 Feb 5.PMID: 19200525 [PubMed - indexed for MEDLINE]Related articlesFree article

Predicting performance on a firefighter's ability test from fitness parameters.

Michaelides MA, Parpa KM, Thompson J, Brown B.

Res Q Exerc Sport. 2008 Dec;79(4):468-75.PMID: 19177948 [PubMed - indexed for MEDLINE]Related articles

Evaluation of the X-linked high-grade myopia locus (MYP1) with cone dysfunction and color vision deficiencies.

Metlapally R, Michaelides M, Bulusu A, Li YJ, Schwartz M, Rosenberg T, Hunt DM, Moore AT, Züchner S, Rickman CB, Young TL.

Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1552-8. Epub 2008 Dec 20.PMID: 19098318 [PubMed - indexed for MEDLINE]Related articles

Skills acquisition and assessment after a microsurgical skills course for ophthalmology residents.

Ezra DG, Aggarwal R, Michaelides M, Okhravi N, Verma S, Benjamin L, Bloom P, Darzi A, Sullivan P.

Ophthalmology. 2009 Feb;116(2):257-62. Epub 2008 Dec 16.PMID: 19091411 [PubMed - indexed for MEDLINE]Related articles

Delusional disorder and alcohol abuse in a patient with Wilson's disease.

Spyridi S, Diakogiannis I, Michaelides M, Sokolaki S, Iacovides A, Kaprinis G.

Gen Hosp Psychiatry. 2008 Nov-Dec;30(6):585-6. Epub 2008 Jul 23.PMID: 19061688 [PubMed - indexed for MEDLINE]Related articles

Bromocriptine administration reduces hyperphagia and adiposity and differentially affects dopamine D2 receptor and transporter binding in leptin-receptor-deficient Zucker rats and rats with diet-induced obesity.

Davis LM, Michaelides M, Cheskin LJ, Moran TH, Aja S, Watkins PA, Pei Z, Contoreggi C, McCullough K, Hope B, Wang GJ, Volkow ND, Thanos PK.

Neuroendocrinology. 2009;89(2):152-62. Epub 2008 Nov 4.PMID: 18984941 [PubMed - indexed for MEDLINE]Related articles

CT guided percutaneous adrenal biopsy for lesions with equivocal findings in chemical shift MR imaging.

Tsitouridis I, Michaelides M, Stratilati S, Sidiropoulos D, Bintoudi A, Rodokalakis G.

Hippokratia. 2008 Jan;12(1):37-42.PMID: 18923755 [PubMed - in process]Related articlesFree article

Automated method for small-animal PET image registration with intrinsic validation.

Pascau J, Gispert JD, Michaelides M, Thanos PK, Volkow ND, Vaquero JJ, Soto-Montenegro ML, Desco M.

Mol Imaging Biol. 2009 Mar-Apr;11(2):107-13. Epub 2008 Aug 1.PMID: 18670824 [PubMed - indexed for MEDLINE]Related articles

Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice.

Yang Z, Chen Y, Lillo C, Chien J, Yu Z, Michaelides M, Klein M, Howes KA, Li Y, Kaminoh Y, Chen H, Zhao C, Chen Y, Al-Sheikh YT, Karan G, Corbeil D, Escher P, Kamaya S, Li C, Johnson S, Frederick JM, Zhao Y, Wang C, Cameron DJ, Huttner WB, Schorderet DF, Munier FL, Moore AT, Birch DG, Baehr W, Hunt DM, Williams DS, Zhang K.

J Clin Invest. 2008 Aug;118(8):2908-16.PMID: 18654668 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin receptor deficiency is associated with upregulation of cannabinoid 1 receptors in limbic brain regions.

Thanos PK, Ramalhete RC, Michaelides M, Piyis YK, Wang GJ, Volkow ND.

Synapse. 2008 Sep;62(9):637-42.PMID: 18563836 [PubMed - indexed for MEDLINE]Related articlesFree article

7-Aminopyrazolo[1,5-a]pyrimidines as potent multitargeted receptor tyrosine kinase inhibitors.

Frey RR, Curtin ML, Albert DH, Glaser KB, Pease LJ, Soni NB, Bouska JJ, Reuter D, Stewart KD, Marcotte P, Bukofzer G, Li J, Davidsen SK, Michaelides MR.

J Med Chem. 2008 Jul 10;51(13):3777-87. Epub 2008 Jun 17.PMID: 18557606 [PubMed - indexed for MEDLINE]Related articles

Posterior mediastinal arteriovenous malformation: report of a case.

Tsitouridis I, Michaelides M, Pervana S.

J Thorac Imaging. 2008 May;23(2):127-30.PMID: 18520571 [PubMed - indexed for MEDLINE]Related articles

Differences in response to food stimuli in a rat model of obesity: in-vivo assessment of brain glucose metabolism.

Thanos PK, Michaelides M, Gispert JD, Pascau J, Soto-Montenegro ML, Desco M, Wang R, Wang GJ, Volkow ND.

Int J Obes (Lond). 2008 Jul;32(7):1171-9. Epub 2008 May 13.PMID: 18475275 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterisation of the macular dystrophy in patients with the A3243G mitochondrial DNA point mutation with fundus autofluorescence.

Rath PP, Jenkins S, Michaelides M, Smith A, Sweeney MG, Davis MB, Fitzke FW, Bird AC.

Br J Ophthalmol. 2008 May;92(5):623-9.PMID: 18441172 [PubMed - indexed for MEDLINE]Related articlesFree article

Phenotypic variation in enhanced S-cone syndrome.

Audo I, Michaelides M, Robson AG, Hawlina M, Vaclavik V, Sandbach JM, Neveu MM, Hogg CR, Hunt DM, Moore AT, Bird AC, Webster AR, Holder GE.

Invest Ophthalmol Vis Sci. 2008 May;49(5):2082-93.PMID: 18436841 [PubMed - indexed for MEDLINE]Related articlesFree article

D2R DNA transfer into the nucleus accumbens attenuates cocaine self-administration in rats.

Thanos PK, Michaelides M, Umegaki H, Volkow ND.

Synapse. 2008 Jul;62(7):481-6.PMID: 18418874 [PubMed - indexed for MEDLINE]Related articlesFree article

A non-invasive method for detecting the metabolic stress response in rodents: characterization and disruption of the circadian corticosterone rhythm.

Thanos PK, Cavigelli SA, Michaelides M, Olvet DM, Patel U, Diep MN, Volkow ND.

Physiol Res. 2009;58(2):219-28. Epub 2008 Apr 1.PMID: 18380537 [PubMed - indexed for MEDLINE]Related articlesFree article

Scaffold oriented synthesis. Part 2: Design, synthesis and biological evaluation of pyrimido-diazepines as receptor tyrosine kinase inhibitors.

Gracias V, Ji Z, Akritopoulou-Zanze I, Abad-Zapatero C, Huth JR, Song D, Hajduk PJ, Johnson EF, Glaser KB, Marcotte PA, Pease L, Soni NB, Stewart KD, Davidsen SK, Michaelides MR, Djuric SW.

Bioorg Med Chem Lett. 2008 Apr 15;18(8):2691-5. Epub 2008 Mar 10.PMID: 18362070 [PubMed - indexed for MEDLINE]Related articles

Post-preeclampsia acute myocardial infarction during puerperium in a woman with normal coronary vessels.

Skoura A, Michaelides M, Trikas A.

Hellenic J Cardiol. 2008 Jan-Feb;49(1):55-8.PMID: 18350784 [PubMed - indexed for MEDLINE]Related articlesFree article

Macular dystrophy associated with the A3243G mitochondrial DNA mutation. Distinct retinal and associated features, disease variability, and characterization of asymptomatic family members.

Michaelides M, Jenkins SA, Bamiou DE, Sweeney MG, Davis MB, Luxon L, Bird AC, Rath PP.

Arch Ophthalmol. 2008 Mar;126(3):320-8.PMID: 18332310 [PubMed - indexed for MEDLINE]Related articlesFree article

The effects of two highly selective dopamine D3 receptor antagonists (SB-277011A and NGB-2904) on food self-administration in a rodent model of obesity.

Thanos PK, Michaelides M, Ho CW, Wang GJ, Newman AH, Heidbreder CA, Ashby CR Jr, Gardner EL, Volkow ND.

Pharmacol Biochem Behav. 2008 Jun;89(4):499-507. Epub 2008 Feb 8.PMID: 18329700 [PubMed - indexed for MEDLINE]Related articlesFree article

The effects of cocaine on regional brain glucose metabolism is attenuated in dopamine transporter knockout mice.

Thanos PK, Michaelides M, Benveniste H, Wang GJ, Volkow ND.

Synapse. 2008 May;62(5):319-24.PMID: 18286542 [PubMed - indexed for MEDLINE]Related articlesFree article

3-amino-benzo[d]isoxazoles as novel multitargeted inhibitors of receptor tyrosine kinases.

Ji Z, Ahmed AA, Albert DH, Bouska JJ, Bousquet PF, Cunha GA, Diaz G, Glaser KB, Guo J, Harris CM, Li J, Marcotte PA, Moskey MD, Oie T, Pease L, Soni NB, Stewart KD, Davidsen SK, Michaelides MR.

J Med Chem. 2008 Mar 13;51(5):1231-41. Epub 2008 Feb 9.PMID: 18260617 [PubMed - indexed for MEDLINE]Related articles

A chemical genomics screen highlights the essential role of mitochondria in HIF-1 regulation.

Lin X, David CA, Donnelly JB, Michaelides M, Chandel NS, Huang X, Warrior U, Weinberg F, Tormos KV, Fesik SW, Shen Y.

Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):174-9. Epub 2008 Jan 2.PMID: 18172210 [PubMed - indexed for MEDLINE]Related articlesFree article

ABCA4 mutations and discordant ABCA4 alleles in patients and siblings with bull's-eye maculopathy.

Michaelides M, Chen LL, Brantley MA Jr, Andorf JL, Isaak EM, Jenkins SA, Holder GE, Bird AC, Stone EM, Webster AR.

Br J Ophthalmol. 2007 Dec;91(12):1650-5.PMID: 18024811 [PubMed - indexed for MEDLINE]Related articles

Identification of aminopyrazolopyridine ureas as potent VEGFR/PDGFR multitargeted kinase inhibitors.

Dai Y, Hartandi K, Soni NB, Pease LJ, Reuter DR, Olson AM, Osterling DJ, Doktor SZ, Albert DH, Bouska JJ, Glaser KB, Marcotte PA, Stewart KD, Davidsen SK, Michaelides MR.

Bioorg Med Chem Lett. 2008 Jan 1;18(1):386-90. Epub 2007 Oct 17.PMID: 18023347 [PubMed - indexed for MEDLINE]Related articles

Functional characteristics of patients with retinal dystrophy that manifest abnormal parafoveal annuli of high density fundus autofluorescence; a review and update.

Robson AG, Michaelides M, Saihan Z, Bird AC, Webster AR, Moore AT, Fitzke FW, Holder GE.

Doc Ophthalmol. 2008 Mar;116(2):79-89. Epub 2007 Nov 6. Review.PMID: 17985165 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional correlates of fundus autofluorescence abnormalities in patients with RPGR or RIMS1 mutations causing cone or cone rod dystrophy.

Robson AG, Michaelides M, Luong VA, Holder GE, Bird AC, Webster AR, Moore AT, Fitzke FW.

Br J Ophthalmol. 2008 Jan;92(1):95-102. Epub 2007 Oct 25.PMID: 17962389 [PubMed - indexed for MEDLINE]Related articles

Food restriction markedly increases dopamine D2 receptor (D2R) in a rat model of obesity as assessed with in-vivo muPET imaging ([11C] raclopride) and in-vitro ([3H] spiperone) autoradiography.

Thanos PK, Michaelides M, Piyis YK, Wang GJ, Volkow ND.

Synapse. 2008 Jan;62(1):50-61.PMID: 17960763 [PubMed - indexed for MEDLINE]Related articles

Glaucoma following congenital cataract surgery--the role of early surgery and posterior capsulotomy.

Michaelides M, Bunce C, Adams GG.

BMC Ophthalmol. 2007 Sep 11;7:13.PMID: 17848200 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of chronic oral methylphenidate on cocaine self-administration and striatal dopamine D2 receptors in rodents.

Thanos PK, Michaelides M, Benveniste H, Wang GJ, Volkow ND.

Pharmacol Biochem Behav. 2007 Oct;87(4):426-33. Epub 2007 Jun 5.PMID: 17599397 [PubMed - indexed for MEDLINE]Related articles

Acute retinal necrosis: a national population-based study to assess the incidence, methods of diagnosis, treatment strategies and outcomes in the UK.

Muthiah MN, Michaelides M, Child CS, Mitchell SM.

Br J Ophthalmol. 2007 Nov;91(11):1452-5. Epub 2007 May 15.PMID: 17504853 [PubMed - indexed for MEDLINE]Related articlesFree article

Residual cone vision without alpha-transducin.

Stockman A, Smithson HE, Michaelides M, Moore AT, Webster AR, Sharpe LT.

J Vis. 2007 Mar 23;7(4):8.PMID: 17461692 [PubMed - indexed for MEDLINE]Related articlesFree article

1,4-Dihydroindeno[1,2-c]pyrazoles with acetylenic side chains as novel and potent multitargeted receptor tyrosine kinase inhibitors with low affinity for the hERG ion channel.

Dinges J, Albert DH, Arnold LD, Ashworth KL, Akritopoulou-Zanze I, Bousquet PF, Bouska JJ, Cunha GA, Davidsen SK, Diaz GJ, Djuric SW, Gasiecki AF, Gintant GA, Gracias VJ, Harris CM, Houseman KA, Hutchins CW, Johnson EF, Li H, Marcotte PA, Martin RL, Michaelides MR, Nyein M, Sowin TJ, Su Z, Tapang PH, Xia Z, Zhang HQ.

J Med Chem. 2007 May 3;50(9):2011-29. Epub 2007 Apr 11.PMID: 17425296 [PubMed - indexed for MEDLINE]Related articles

Discovery of N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea (ABT-869), a 3-aminoindazole-based orally active multitargeted receptor tyrosine kinase inhibitor.

Dai Y, Hartandi K, Ji Z, Ahmed AA, Albert DH, Bauch JL, Bouska JJ, Bousquet PF, Cunha GA, Glaser KB, Harris CM, Hickman D, Guo J, Li J, Marcotte PA, Marsh KC, Moskey MD, Martin RL, Olson AM, Osterling DJ, Pease LJ, Soni NB, Stewart KD, Stoll VS, Tapang P, Reuter DR, Davidsen SK, Michaelides MR.

J Med Chem. 2007 Apr 5;50(7):1584-97. Epub 2007 Mar 8.PMID: 17343372 [PubMed - indexed for MEDLINE]Related articles

Bilateral epiretinal membranes in Gorlin syndrome associated with a novel PTCH mutation.

Scott A, Strouthidis NG, Robson AG, Forsyth J, Maher ER, Schlottmann PG, Michaelides M.

Am J Ophthalmol. 2007 Feb;143(2):346-8. Epub 2006 Oct 23.PMID: 17258529 [PubMed - indexed for MEDLINE]Related articles

Genetic enhancement of cognition in a kindred with cone-rod dystrophy due to RIMS1 mutation.

Sisodiya SM, Thompson PJ, Need A, Harris SE, Weale ME, Wilkie SE, Michaelides M, Free SL, Walley N, Gumbs C, Gerrelli D, Ruddle P, Whalley LJ, Starr JM, Hunt DM, Goldstein DB, Deary IJ, Moore AT.

J Med Genet. 2007 Jun;44(6):373-80. Epub 2007 Jan 19.PMID: 17237123 [PubMed - indexed for MEDLINE]Related articles

ABT-869, a multitargeted receptor tyrosine kinase inhibitor: inhibition of FLT3 phosphorylation and signaling in acute myeloid leukemia.

Shankar DB, Li J, Tapang P, Owen McCall J, Pease LJ, Dai Y, Wei RQ, Albert DH, Bouska JJ, Osterling DJ, Guo J, Marcotte PA, Johnson EF, Soni N, Hartandi K, Michaelides MR, Davidsen SK, Priceman SJ, Chang JC, Rhodes K, Shah N, Moore TB, Sakamoto KM, Glaser KB.

Blood. 2007 Apr 15;109(8):3400-8. Epub 2007 Jan 5.PMID: 17209055 [PubMed - indexed for MEDLINE]Related articlesFree article

Thienopyridine urea inhibitors of KDR kinase.

Heyman HR, Frey RR, Bousquet PF, Cunha GA, Moskey MD, Ahmed AA, Soni NB, Marcotte PA, Pease LJ, Glaser KB, Yates M, Bouska JJ, Albert DH, Black-Schaefer CL, Dandliker PJ, Stewart KD, Rafferty P, Davidsen SK, Michaelides MR, Curtin ML.

Bioorg Med Chem Lett. 2007 Mar 1;17(5):1246-9. Epub 2006 Dec 9.PMID: 17188869 [PubMed - indexed for MEDLINE]Related articles